dihydroxyphenylalanine has been researched along with Chorea in 31 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects." | 1.26 | CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977) |
| "A case of paroxysmal kinesigenic choreoathetosis is described." | 1.25 | Paroxysmal kinesigenic choreoathetosis. Report of a case relieved by L-dopa. ( Loong, SC; Ong, YY, 1973) |
| " On the basis of this experience it seems that the drug can be used safely and effectively on an outpatient basis provided that dosage increments are introduced gradually, maximum dosage is limited to 4 g." | 1.25 | Metabolic studies and clinical observations during L-dopa treatment of Parkinson's disease. ( Bianchine, JR; Peaston, MJ, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (96.77) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HIRSCHMANN, J | 1 |
| MAYER, K | 1 |
| SOURKES, TL | 1 |
| PIVNICKI, D | 1 |
| BROWN, WT | 1 |
| WISEMAN-DISTLER, H | 1 |
| MURPHY, GF | 1 |
| SANKOFF, I | 1 |
| SAINTCYR, S | 1 |
| Otsuka, M | 1 |
| Ichiya, Y | 1 |
| Kuwabara, Y | 1 |
| Hosokawa, S | 1 |
| Sasaki, M | 1 |
| Fukumura, T | 1 |
| Masuda, K | 1 |
| Goto, I | 1 |
| Kato, M | 1 |
| Davidson, DL | 1 |
| Yates, CM | 1 |
| Mawdsley, C | 1 |
| Pullar, IA | 1 |
| Wilson, H | 1 |
| Proctor, P | 1 |
| McGinness, JE | 1 |
| Bulandra, R | 1 |
| Serbanesco, A | 1 |
| Calne, DB | 1 |
| Stern, GM | 1 |
| Laurence, DR | 1 |
| Sharkey, J | 1 |
| Armitage, P | 1 |
| Crawford, JP | 2 |
| Godwin-Austen, RB | 1 |
| Frears, CC | 1 |
| Bergmann, S | 1 |
| Parkes, JD | 1 |
| Knill-Jones, RP | 1 |
| Birkmayer, W | 4 |
| Hartmann-von Monakow, K | 1 |
| Klawans, HL | 1 |
| Constantinidis, J | 1 |
| Mentasti, M | 1 |
| Sigwald, J | 1 |
| Chomette, G | 1 |
| Raymondeaud, C | 1 |
| Tarsy, D | 1 |
| Leopold, N | 1 |
| Sax, DS | 1 |
| Gordon, N | 1 |
| Neumayer, E | 1 |
| Presthus, J | 1 |
| Barbeau, A | 1 |
| Loong, SC | 1 |
| Ong, YY | 1 |
| Markham, C | 1 |
| Diamond, SG | 1 |
| Treciokas, LJ | 1 |
| Degkwitz, R | 1 |
| Narabayashi, H | 1 |
| Cools, AR | 1 |
| Duvoisin, RC | 1 |
| Yahr, MD | 1 |
| Coté, LD | 1 |
| Peaston, MJ | 1 |
| Bianchine, JR | 1 |
| Sacks, OW | 1 |
| Messeloff, CR | 1 |
| Schwartz, WF | 1 |
| Tissot, R | 1 |
| Gaillard, JM | 1 |
| Guggisberg, M | 1 |
| Gauthier, G | 1 |
| de Ajuriaguerra, J | 1 |
4 reviews available for dihydroxyphenylalanine and Chorea
| Article | Year |
|---|---|
The pharmacology of extrapyramidal movement disorders.
Topics: Basal Ganglia Diseases; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Hep | 1973 |
The importance of monoamine metabolism for the pathology of the extrapyramidal system.
Topics: Aged; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Catechol Oxidase; Catecholamines | 1969 |
[Long term treatment of a parkinsonism with l-dopa].
Topics: Administration, Oral; Athetosis; Chorea; Dihydroxyphenylalanine; Humans; Nausea; Parkinson Disease; | 1973 |
[l-dopa treatment of Parkinson's syndrome and mechanism of action of neuroleptics].
Topics: Acetylcholine; Basal Ganglia; Butyrophenones; Chorea; Dihydroxyphenylalanine; Dopamine; Extrapyramid | 1969 |
2 trials available for dihydroxyphenylalanine and Chorea
| Article | Year |
|---|---|
L-dopa in postencephalitic parkinsonism.
Topics: Aged; Athetosis; Chorea; Clinical Trials as Topic; Delusions; Dihydroxyphenylalanine; Female; Humans | 1969 |
Combined treatment of parkinsonism with L-dopa and amantadine.
Topics: Aged; Amantadine; Chorea; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Hypotens | 1970 |
25 other studies available for dihydroxyphenylalanine and Chorea
| Article | Year |
|---|---|
[ON THE CONTROL OF AKINESIA AND OTHER EXTRAPYRAMIDAL MOTOR DISORDERS WITH L-DOPA (L-DIHYDROXYPHENYLALANINE)].
Topics: Chorea; Dihydroxyphenylalanine; Electromyography; Extrapyramidal Tracts; Humans; Levodopa; Monoamine | 1964 |
A CLINICAL AND METABOLIC STUDY OF DOPA (3, 4-DIHYDROXYPHENYLALANINE) AND METHYLDOPA IN HUNTINGTON'S CHOREA.
Topics: Body Fluids; Chorea; Dihydroxyphenylalanine; Drug Therapy; Electroencephalography; Fluids and Secret | 1965 |
Cerebral glucose metabolism and striatal 18F-dopa uptake by PET in cases of chorea with or without dementia.
Topics: Adult; Aged; Brain; Caudate Nucleus; Chorea; Corpus Striatum; Dementia; Dihydroxyphenylalanine; Fema | 1993 |
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; | 1977 |
Levodopa side-effects and the Lesch-Nyhan syndrome.
Topics: Athetosis; Chorea; Compulsive Behavior; Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Int | 1970 |
[Dopamine and the parkinsonism-chorea antagonism].
Topics: Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disorders; Parkinson Disease; Phenothiazi | 1972 |
Dopa in parkinson's disease.
Topics: Chorea; Dihydroxyphenylalanine; Humans; Parkinson Disease; Schizophrenia | 1969 |
Side-effects of L-dopa in postencephalitic parkinsonism.
Topics: Chorea; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Myoclonus; Parkinson Disease, Postencep | 1970 |
[Experimental findings and new aspects in extrapyramidal diseases].
Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Do | 1966 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1969 |
[Monoamines and choreic syndromes].
Topics: Amines; Butyrophenones; Chorea; Diazepam; Dihydroxyphenylalanine; Dopamine; Ganglia; Globus Pallidus | 1972 |
[Further experimental studies on the catecholamine metabolism in extrapyramidal diseases (Parkinson and chorea syndromes)].
Topics: Aged; Carboxy-Lyases; Catecholamines; Chorea; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Ma | 1967 |
[Antagonism and competition between Parkinson's syndrome and the chorea and athetosis syndrome. Clinical cases of the association (including an anatomoclinical case). The abnormal movements provoked by levodopa in Parkinsonian patients].
Topics: Adult; Athetosis; Basal Ganglia; Brain; Chorea; Dihydroxyphenylalanine; Female; Globus Pallidus; Hum | 1972 |
Physostigmine in choreiform movement disorders.
Topics: Acetylcholine; Adult; Aged; Art; Athetosis; Chorea; Corpus Striatum; Dihydroxyphenylalanine; Female; | 1974 |
Drugs and motor functions.
Topics: Athetosis; Catecholamines; Cholinesterase Inhibitors; Chorea; Dihydroxyphenylalanine; Dopamine; Extr | 1971 |
[L-tryptophan therapy of DOPA psychoses].
Topics: Aged; Athetosis; Cardiovascular Diseases; Chorea; Constipation; Dihydroxyphenylalanine; Feeding and | 1972 |
[The use of levodopa in diseases other than Parkinsonism].
Topics: Chorea; Coma; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Endocrine System Diseases; Hear | 1972 |
Paroxysmal kinesigenic choreoathetosis. Report of a case relieved by L-dopa.
Topics: Adult; Amitriptyline; Athetosis; Chlordiazepoxide; Chorea; Dihydroxyphenylalanine; Humans; Male; Phe | 1973 |
Carbidopa in Parkinson disease and in nausea and vomiting of levodopa.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Hum | 1974 |
[Present status and future problems of stereoencephalotomy].
Topics: Athetosis; Brain; Brain Neoplasms; Chorea; Dihydroxyphenylalanine; Epilepsy; Humans; Myoclonus; Park | 1971 |
Athetoid and choreiform hyperkinesias produced by caudate application of dopamine in cats.
Topics: Animals; Athetosis; Behavior, Animal; Cats; Caudate Nucleus; Chorea; Dextroamphetamine; Dihydroxyphe | 1972 |
Pyridoxine reversal of L-dopa effects in Parkinsonism.
Topics: Chorea; Dihydroxyphenylalanine; Humans; Parkinson Disease; Pyridoxine | 1969 |
Metabolic studies and clinical observations during L-dopa treatment of Parkinson's disease.
Topics: Age Factors; Aged; Athetosis; Carbon Isotopes; Chorea; Dihydroxyphenylalanine; Female; Humans; Intes | 1970 |
Long-term effects of levodopa in the severely disabled patient.
Topics: Chorea; Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders; Parkinson Disease; Parkins | 1970 |
[Treatment of Parkinsonism with oral L-DOPA combined with a decarboxylase inhibitor (Ro IV 46.02)].
Topics: Adult; Aged; Anemia, Hemolytic; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Cell Count; Carb | 1969 |