dihydroxyphenylalanine has been researched along with Childhood Torsion Disease in 37 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Striatal 18F-Dopa uptake and glucose metabolism were studied by positron emission tomography with 6-L-[18F]fluorodopa and [18F]fluorodeoxyglucose, respectively, in 8 patients with idiopathic dystonia." | 3.68 | Increased striatal 18F-dopa uptake and normal glucose metabolism in idiopathic dystonia syndrome. ( Fukumura, T; Goto, I; Ichiya, Y; Kato, M; Kuwabara, Y; Masuda, K; Otsuka, M; Sasaki, M; Shima, F, 1992) |
| "Many different disorders have dystonia as the only or primary sign." | 2.40 | Dystonia. ( Bressman, SB, 1998) |
| "The cause of Dystonia Musculorum Deformans (DMD) is most frequently unknown, therefore the treatment can only be symptomatic and often disappointing." | 2.40 | [Recessive dopa-responsive form of dystonia due to a mutation of the tyrosine hydroxylase gene]. ( Rondot, P; Wevers, RA, 1999) |
| "It is known that most cases of idiopathic torsion dystonia (ITD) are inherited in an autosomal dominant fashion." | 1.29 | Striatal [18F]dopa uptake in familial idiopathic dystonia. ( Brooks, DJ; Fletcher, NA; Marsden, CD; Playford, ED; Sawle, GV, 1993) |
| "Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects." | 1.26 | CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977) |
| " This study was initiated following significant symptomatic worsening by the patient with supplemental ascorbic acid at a dosage of 2 g/day." | 1.26 | Effect of supplemental ascorbic acid in a case of torsion dystonia. ( Mars, H, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (86.49) | 18.7374 |
| 1990's | 5 (13.51) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arushanian, EB | 1 |
| Dutov, AA | 1 |
| Playford, ED | 1 |
| Fletcher, NA | 1 |
| Sawle, GV | 1 |
| Marsden, CD | 1 |
| Brooks, DJ | 1 |
| Gasser, T | 1 |
| Bressman, SB | 1 |
| Rondot, P | 1 |
| Wevers, RA | 1 |
| Davidson, DL | 1 |
| Yates, CM | 1 |
| Mawdsley, C | 1 |
| Pullar, IA | 1 |
| Wilson, H | 1 |
| Barkatova, VP | 1 |
| Barkhatova, VP | 1 |
| Markova, ED | 1 |
| Mosunova, TG | 1 |
| Mars, H | 1 |
| Otsuka, M | 1 |
| Ichiya, Y | 1 |
| Shima, F | 1 |
| Kuwabara, Y | 1 |
| Sasaki, M | 1 |
| Fukumura, T | 1 |
| Kato, M | 1 |
| Masuda, K | 1 |
| Goto, I | 1 |
| Cooper, IS | 3 |
| Rajput, AH | 2 |
| Hongladarom, T | 1 |
| Eldridge, R | 2 |
| Kanter, W | 1 |
| Koerber, T | 1 |
| Keegan, DL | 1 |
| Hartmann-von Monakow, K | 1 |
| Papeschi, R | 1 |
| Molina-Negro, P | 1 |
| Sourkes, TL | 1 |
| Erba, G | 1 |
| Chase, TN | 2 |
| Gordon, EK | 1 |
| Ng, LK | 1 |
| Klawans, HL | 1 |
| Coleman, MP | 1 |
| Barnet, A | 1 |
| Saïd, G | 1 |
| Barbeau, A | 2 |
| Hare, TA | 1 |
| Beasley, BL | 1 |
| Chambers, RA | 1 |
| Boehme, DH | 1 |
| Vogel, WH | 1 |
| Andrews, CJ | 1 |
| Mel'nichuk, PV | 1 |
| Sosnovskaia, LS | 1 |
| Coleman, M | 2 |
| Samler, L | 1 |
| Herishanu, Y | 1 |
| Loewinger, E | 1 |
| North, RR | 1 |
| Guggenheim, MA | 1 |
| Dodge, PR | 1 |
| Mandell, S | 1 |
| Barrett, RE | 1 |
| Yahr, MD | 1 |
| Duvoisin, RC | 1 |
5 reviews available for dihydroxyphenylalanine and Childhood Torsion Disease
| Article | Year |
|---|---|
[Nigrostriatal system as a source of torsion extrapyramidal disorders (review)].
Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Basal Ganglia Diseases; Cats; Caudate Nucleus; Corpus S | 1980 |
Idiopathic, myoclonic and Dopa-responsive dystonia.
Topics: Dihydroxyphenylalanine; Dystonia; Dystonia Musculorum Deformans; Humans; Myoclonus; Phenotype | 1997 |
Dystonia.
Topics: Age of Onset; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Dystonia Musculorum Deformans; Gene | 1998 |
[Recessive dopa-responsive form of dystonia due to a mutation of the tyrosine hydroxylase gene].
Topics: Dihydroxyphenylalanine; Dopamine Agents; Dystonia Musculorum Deformans; Genes, Recessive; Humans; Mu | 1999 |
The pharmacology of extrapyramidal movement disorders.
Topics: Basal Ganglia Diseases; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Hep | 1973 |
2 trials available for dihydroxyphenylalanine and Childhood Torsion Disease
| Article | Year |
|---|---|
A double-blind crossover study of the L-dopa treatment of torsion dystonia in identical twins.
Topics: Adult; Clinical Trials as Topic; Dihydroxyphenylalanine; Diseases in Twins; Dystonia Musculorum Defo | 1970 |
Preliminary remarks on the L-dopa therapy of dystonia.
Topics: Activities of Daily Living; Adolescent; Adult; Child; Dihydroxyphenylalanine; Diseases in Twins; Dys | 1970 |
30 other studies available for dihydroxyphenylalanine and Childhood Torsion Disease
| Article | Year |
|---|---|
Striatal [18F]dopa uptake in familial idiopathic dystonia.
Topics: Adult; Corpus Striatum; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Fluorine Radi | 1993 |
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; | 1977 |
[Catecholamine excretion in torsion dystonia].
Topics: Adolescent; Adult; Aged; Catecholamines; Child; Dihydroxyphenylalanine; Dopamine; Dystonia Musculoru | 1978 |
[Pathogenesis and treatment of torsion dystonia].
Topics: Carbidopa; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Epinephrine; Homovanilli | 1978 |
[Catecholamines metabolism in extrapyramidal disorders in children].
Topics: Adolescent; Ataxia Telangiectasia; Basal Ganglia Diseases; Catecholamines; Child; Child, Preschool; | 1977 |
Effect of supplemental ascorbic acid in a case of torsion dystonia.
Topics: Adult; Ascorbic Acid; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Epinephrine; | 1976 |
Increased striatal 18F-dopa uptake and normal glucose metabolism in idiopathic dystonia syndrome.
Topics: Adult; Caudate Nucleus; Deoxyglucose; Dihydroxyphenylalanine; Dopamine; Dystonia; Dystonia Musculoru | 1992 |
Levodopa-induced dystonia.
Topics: Adolescent; Adult; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Humans; Mal | 1972 |
Levodopa in dystonia musculorum deformans.
Topics: Adolescent; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Humans | 1973 |
Levodopa in dystonia musculorum deformans.
Topics: Adolescent; Child; Child, Preschool; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Follow-U | 1973 |
Letter: Levodopa in dystonia.
Topics: Age Factors; Dihydroxyphenylalanine; Drug Evaluation; Dystonia Musculorum Deformans; Humans; Sex Fac | 1973 |
Drug induced dystonia tarda: treatment with L-dopa.
Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Diazepam; Dihydroxyphenylalanine; Dystonia Mu | 1973 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1969 |
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp | 1972 |
Norepinephrine metabolism in the central nervous system of man: studies using 3-methoxy-4-hydroxyphenylethylene glycol levels in cerebrospinal fluid.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Carbon Radioisotopes; Cerebrospinal Fluid; Child; | 1973 |
L-dopa reversal of muscular spasm, vomiting and insomnia in a patient with an atypical form of familial dystonia.
Topics: Adolescent; Blood Platelets; Child; Diarrhea; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; | 1969 |
[Symposium on diseases of the basal ganglia. Physiological and clinical implications of thalamic surgery for dystonia and torticollis. II].
Topics: Adolescent; Adult; Basal Ganglia; Catecholamines; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1968 |
[Dystonias].
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Extra | 1972 |
[The use of levodopa in diseases other than Parkinsonism].
Topics: Chorea; Coma; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Endocrine System Diseases; Hear | 1972 |
DOPA and amino acid levels in plasma and cerebrospinal fluid of patients with Parkinson's disease before and during treatment with L-DOPA.
Topics: Administration, Oral; Adult; Aged; Amino Acids; Animals; Autoanalysis; Child; Dihydroxyphenylalanine | 1973 |
Influence of dystonia on the response to long-term L-dopa therapy in Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Electromyography; Evaluation Studies as | 1973 |
[L-DOPA therapy of deforming muscular dystonia in children].
Topics: Adolescent; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Humans; Hyperkines | 1973 |
Rationale for the use of L-dopa in the torsion dystonias.
Topics: Animals; Basal Ganglia; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Haplorhini; | 1970 |
'Torsion dystony' and abnormal copper metabolism.
Topics: Adult; Ceruloplasmin; Copper; Diagnosis, Differential; Diazepam; Dihydroxyphenylalanine; Dystonia Mu | 1972 |
Drug-induced movement disorders.
Topics: Amphetamine; Contraceptives, Oral; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Hu | 1971 |
Unusual arm movements with onset in childhood--a nosologic entity?
Topics: Child; Diagnosis, Differential; Diazepam; Dihydroxyphenylalanine; Diphenhydramine; Dystonia Musculor | 1970 |
The treatment of dystonia with L-dopa and haloperidol.
Topics: Adolescent; Adult; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Haloperidol | 1970 |
Torsion dystonia and spasmodic torticollis--results of treatment with L-dopa.
Topics: Acute Disease; Adolescent; Adult; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Fema | 1970 |
Biochemical and pharmacologic studies of dystonia.
Topics: Adult; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Humans; Hydroxyindoleac | 1970 |
Neurosurgical treatment of dystonia.
Topics: Adolescent; Adult; Child; Cryosurgery; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female | 1970 |