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dihydroxyphenylalanine and Cerebral Palsy

dihydroxyphenylalanine has been researched along with Cerebral Palsy in 6 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"Strategies in treatment of movement disorders are discussed with the illustration of three patients with dystonia."1.33Treatment strategies in movement disorders. ( Speelman, JD, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Speelman, JD1
Papeschi, R1
Molina-Negro, P1
Sourkes, TL1
Erba, G1
Papavasiliou, PS1
Cotzias, GC1
Düby, SE1
Steck, AJ1
Fehling, C1
Bell, MA1
Rosenthal, RK1
McDowell, FH1
Cooper, W1
Chyatte, SB1
Birdsong, JH1
Mrozek, K1
Kamińska, A1
Marciniak, M1

Trials

2 trials available for dihydroxyphenylalanine and Cerebral Palsy

ArticleYear
Levodopa in Parkinsonism: potentiation of central effects with a peripheral inhibitor.
    The New England journal of medicine, 1972, Jan-06, Volume: 286, Issue:1

    Topics: Administration, Oral; Adult; Biotransformation; Brain; Carbon Monoxide Poisoning; Cerebral Palsy; Ch

1972
Levodopa therapy in athetoid cerebral palsy. A preliminary report.
    Neurology, 1972, Volume: 22, Issue:1

    Topics: Activities of Daily Living; Adolescent; Adult; Cerebral Palsy; Clinical Trials as Topic; Dihydroxyph

1972

Other Studies

4 other studies available for dihydroxyphenylalanine and Cerebral Palsy

ArticleYear
Treatment strategies in movement disorders.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:3

    Topics: Adult; Botulinum Toxins; Cerebral Palsy; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female;

2005
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
    Neurology, 1972, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp

1972
Methods-time measurement in assessment of motor performance.
    Archives of physical medicine and rehabilitation, 1972, Volume: 53, Issue:1

    Topics: Central Nervous System Diseases; Cerebral Palsy; Dihydroxyphenylalanine; Hemiplegia; Humans; Methods

1972
[Attempt at Larodopa and Viregyt treatment in a case of progressive supranuclear palsy].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1972, Jul-01, Volume: 25, Issue:11

    Topics: Amantadine; Cerebral Palsy; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Middle Aged

1972