dihydroxyphenylalanine has been researched along with Cataract in 5 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ability of N-beta-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine (5-S-GAD)-a novel catechol derivative isolated from an insect as an antibacterial substance-to scavenge free radicals and prevent cataract progression was examined." | 3.75 | 5-S-GAD, a novel radical scavenging compound, prevents lens opacity development. ( Akiyama, N; Natori, S; Nishigori, H; Sogo, S; Tsujimoto, M; Umeda, IO, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akiyama, N | 1 |
| Umeda, IO | 1 |
| Sogo, S | 1 |
| Nishigori, H | 1 |
| Tsujimoto, M | 1 |
| Natori, S | 2 |
| Kawada, H | 1 |
| Kojima, M | 1 |
| Kimura, T | 1 |
| Sasaki, K | 1 |
| Sasaki, H | 1 |
| Molnár, GA | 1 |
| Nemes, V | 1 |
| Biró, Z | 1 |
| Ludány, A | 1 |
| Wagner, Z | 1 |
| Wittmann, I | 1 |
| Truscott, RJ | 1 |
| Martinez, MG | 1 |
| Pirie, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Single Center, Randomized, Placebo-controlled, Double-blind, Parallel Group Study to Evaluate Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis[NCT03278730] | Phase 2 | 296 participants (Anticipated) | Interventional | 2025-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for dihydroxyphenylalanine and Cataract
| Article | Year |
|---|---|
5-S-GAD, a novel radical scavenging compound, prevents lens opacity development.
Topics: alpha-Crystallins; Animals; Biphenyl Compounds; Carnosine; Cataract; Cells, Cultured; Chick Embryo; | 2009 |
Effect of 5-S-GAD on UV-B-induced cataracts in rats.
Topics: Administration, Topical; Animals; Antioxidants; Cataract; Chromatography, High Pressure Liquid; Dihy | 2009 |
Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase.
Topics: Aged; Cataract; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dihydroxyphenylalanine; Eye Prot | 2005 |
Decolouration of the lens pigment in senile nuclear cataract.
Topics: 3-Hydroxyanthranilic Acid; Animals; Borohydrides; Cataract; Cattle; Crystallins; Dihydroxyphenylalan | 1990 |
Reaction of tyrosine oxidation products with proteins of the lens.
Topics: Animals; Ascorbic Acid; Cataract; Catechol Oxidase; Cattle; Chemical Phenomena; Chemistry; Chromatog | 1968 |