dihydroxyphenylalanine has been researched along with Cardiac Failure in 17 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following an outline of the medicinal chemistry bases of the development of these prodrugs, laboratory and clinical pharmacology of ibopamine, levodopa, gludopa, and TA-870 are reviewed, pointing out the interesting indications of various preliminary studies in heart failure, essential hypertension, and renal failure on the one hand, and the extensive therapeutic experience with ibopamine as an "inodilator" in the chronic treatment of congestive heart failure on the other hand." | 4.77 | Cardiovascular and renal action of dopaminergic prodrugs. ( Casagrande, C; Ferrini, R; Merlo, L; Miragoli, G; Semeraro, C, 1989) |
| "05), indicative of increased central nervous system turnover of both catecholamines, occurred in cardiac failure and was quantitatively linked to the degree of activation of the cardiac sympathetic nervous outflow, as was the jugular overflow of the principal serotonin metabolite, 5-hydroxyindoleacetic acid." | 3.69 | Increased central nervous system monoamine neurotransmitter turnover and its association with sympathetic nervous activity in treated heart failure patients. ( Cox, HS; Esler, MD; Jennings, GL; Kaye, DM; Lambert, GW; Lefkovits, J; Turner, AG, 1995) |
| "Although heart failure is generally accompanied by sympathoexcitation, the integrity of cardiac sympathetic nerve function in heart failure remains controversial, particularly in relation to nerve firing activity and to the capacity of sympathetic nerves to recapture norepinephrine." | 1.29 | Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure. ( Esler, MD; Jennings, G; Kaye, DM; Lambert, GW; Lefkovits, J; Morris, M, 1994) |
| "Subjects with and without congestive heart failure received intravenous infusions of [(3)H]NE." | 1.29 | Cardiac sympathetic nerve function in congestive heart failure. ( Eisenhofer, G; Esler, MD; Friberg, P; Goldstein, DS; Kaye, DM; Kopin, IJ; Lambert, G; Quyyumi, AA; Rundqvist, B, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, X | 1 |
| Hou, Q | 1 |
| Li, X | 1 |
| Yu, Z | 1 |
| Dong, X | 1 |
| Yan, F | 1 |
| Nigmatullina, RR | 1 |
| Kirillova, VV | 2 |
| Jourjikiya, RK | 1 |
| Mukhamedyarov, MA | 1 |
| Kudrin, VS | 2 |
| Klodt, PM | 2 |
| Palotás, A | 1 |
| Nigmatullin, RR | 1 |
| Dzhordzhikiia, RK | 1 |
| Lambert, GW | 3 |
| Kaye, DM | 3 |
| Lefkovits, J | 2 |
| Jennings, GL | 2 |
| Turner, AG | 1 |
| Cox, HS | 1 |
| Esler, MD | 4 |
| Wang, ZQ | 1 |
| Way, D | 1 |
| Shimizu, K | 1 |
| Fong, F | 1 |
| Trigg, L | 1 |
| McGrath, BP | 1 |
| Morris, M | 1 |
| Jennings, G | 1 |
| Meredith, IT | 1 |
| Eisenhofer, G | 2 |
| Dewar, EM | 1 |
| Friberg, P | 1 |
| Rundqvist, B | 1 |
| Quyyumi, AA | 1 |
| Lambert, G | 1 |
| Kopin, IJ | 1 |
| Goldstein, DS | 1 |
| Hartmann, C | 1 |
| McIntire, WS | 1 |
| Casagrande, C | 1 |
| Merlo, L | 1 |
| Ferrini, R | 1 |
| Miragoli, G | 1 |
| Semeraro, C | 1 |
| Alousi, AA | 1 |
| Beards, JA | 1 |
| Bock, KD | 1 |
| Jenkins, RB | 1 |
| Mendelson, SH | 1 |
| Lamid, S | 1 |
| Klawans, HL | 1 |
| Goldberg, LI | 2 |
| Valori, C | 1 |
| Alicandri, C | 1 |
| Renzini, V | 1 |
| Sotskova, TV | 1 |
| Finlay, GD | 1 |
| Whitsett, TL | 1 |
| Cucinell, EA | 1 |
4 reviews available for dihydroxyphenylalanine and Cardiac Failure
| Article | Year |
|---|---|
Prenatal two-and three-dimensional echocardiographic diagnosis of ductal anomalous origin of the left pulmonary artery: Case report and literature review.
Topics: Dihydroxyphenylalanine; Echocardiography; Echocardiography, Three-Dimensional; Female; Fetal Heart; | 2023 |
Cardiovascular and renal action of dopaminergic prodrugs.
Topics: Animals; Cardiotonic Agents; Cats; Chemical Phenomena; Chemistry; Deoxyepinephrine; Dihydroxyphenyla | 1989 |
Cardiovascular and renal actions of dopamine: potential clinical applications.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Cats; Coronary Circulation; Dihydroxyphenylalanine; Do | 1972 |
[The 3d catecholamine--dopamine].
Topics: Animals; Asthma; Brain Chemistry; Brain Injuries; Cardiovascular Diseases; Dihydroxyphenylalanine; D | 1970 |
1 trial available for dihydroxyphenylalanine and Cardiac Failure
| Article | Year |
|---|---|
Augmentation of sodium and potassium excretion, glomerular filtration rate and renal plasma flow by levodopa.
Topics: Administration, Oral; Aged; Aminohippuric Acids; Blood Pressure; Clinical Trials as Topic; Dihydroxy | 1971 |
12 other studies available for dihydroxyphenylalanine and Cardiac Failure
| Article | Year |
|---|---|
Disrupted serotonergic and sympathoadrenal systems in patients with chronic heart failure may serve as new therapeutic targets and novel biomarkers to assess severity, progression and response to treatment.
Topics: Adrenal Glands; Adrenergic beta-Antagonists; Adult; Biomarkers; Chronic Disease; Dihydroxyphenylalan | 2009 |
[The state of sympathetic-adrenal system in patients with chronic cardiac insufficiency].
Topics: Adrenal Glands; Chronic Disease; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Heart Failur | 2009 |
Increased central nervous system monoamine neurotransmitter turnover and its association with sympathetic nervous activity in treated heart failure patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Cardiotonic Agents; Case-Control Studies; | 1995 |
Beneficial acute effects of selective modulation of renal dopamine system by gamma-L-glutamyl-L-dopa in rabbits with congestive heart failure.
Topics: Animals; Benzazepines; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Doxorubicin; Heart Failure; | 1993 |
Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure.
Topics: Brain; Dihydroxyphenylalanine; Heart; Heart Failure; Humans; Methoxyhydroxyphenylglycol; Middle Aged | 1994 |
Cardiac sympathetic nervous activity in congestive heart failure. Evidence for increased neuronal norepinephrine release and preserved neuronal uptake.
Topics: Coronary Disease; Desipramine; Dihydroxyphenylalanine; Heart; Heart Failure; Humans; Male; Middle Ag | 1993 |
Cardiac sympathetic nerve function in congestive heart failure.
Topics: Adolescent; Adult; Aged; Catecholamines; Dihydroxyphenylalanine; Exercise Test; Female; Heart; Heart | 1996 |
Amine-oxidizing quinoproteins.
Topics: Amino Acid Sequence; Coenzymes; Copper; Diabetes Mellitus; Dihydroxyphenylalanine; Electron Spin Res | 1997 |
Catecholamine, protein, and RNA content in advanced congestive heart failure in the Syrian hamster.
Topics: Animals; Cardiomegaly; Cricetinae; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Heart; | 1972 |
[Conservative treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aniline Compounds; Dihydroxyphenylalanine; Female; Guaneth | 1970 |
Levodopa therapy of patients with Parkinsonism and heart disease.
Topics: Aged; Angina Pectoris; Anti-Arrhythmia Agents; Aortic Valve Stenosis; Arrhythmias, Cardiac; Coronary | 1972 |
[Tissue depletion of catecholamines in congestive heart failure].
Topics: Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Heart Failure; Humans; Norepinephrine | 1972 |