Compounds > dihydroxyphenylalanine
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dihydroxyphenylalanine and Cancer of Gastrointestinal Tract

dihydroxyphenylalanine has been researched along with Cancer of Gastrointestinal Tract in 9 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Research Excerpts

ExcerptRelevanceReference
"The greatest impact was observed for carcinoid tumors (50%: 11 of 22) and was clinically relevant in every case, followed by occult endocrine tumors (16%: four of 25), and was clinically relevant in three of the four cases, and noncarcinoid tumors (13%: 3 of 22), clinically relevant in only one case."1.35Impact of fluorodihydroxyphenylalanine-18F positron emission tomography on management of adult patients with documented or occult digestive endocrine tumors. ( Bouchard, P; Duron, F; Grangé, JD; Houry, S; Huchet, V; Kerrou, K; Lotz, JP; Montravers, F; Nataf, V; Rougier, P; Ruszniewski, P; Talbot, JN, 2009)
"The localization of carcinoids in the gastrointestinal tract is frequently difficult if not impossible with the imaging procedures used to date."1.30Imaging of a metastatic gastrointestinal carcinoid by F-18-DOPA positron emission tomography. ( Hoegerle, S; Kraft, A; Moser, E; Nitzsche, EU; Schneider, B, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Barachini, O1
Bernt, R1
Mirzaei, S1
Pirich, C1
Hergan, K1
Zandieh, S1
Leroy Freschini, B1
Addeo, P1
Averous, G1
Goichot, B1
Bachellier, P1
Imperiale, A1
Shamim, SA1
Kumar, A1
Kumar, R1
Montravers, F1
Kerrou, K1
Nataf, V1
Huchet, V1
Lotz, JP1
Ruszniewski, P1
Rougier, P1
Duron, F1
Bouchard, P1
Grangé, JD1
Houry, S1
Talbot, JN1
Koopmans, KP2
Brouwers, AH1
De Hooge, MN1
Van der Horst-Schrivers, AN1
Kema, IP1
Wolffenbuttel, BH1
De Vries, EG2
Jager, PL2
Ambrosini, V1
Tomassetti, P1
Castellucci, P1
Campana, D1
Montini, G1
Rubello, D1
Nanni, C1
Rizzello, A1
Franchi, R1
Fanti, S1
Hoegerle, S2
Schneider, B1
Kraft, A1
Moser, E2
Nitzsche, EU1
Altehoefer, C1
Ghanem, N1
Koehler, G1
Waller, CF1
Scheruebl, H1
Nitzsche, E1

Reviews

1 review available for dihydroxyphenylalanine and Cancer of Gastrointestinal Tract

ArticleYear
PET/Computed Tomography in Neuroendocrine Tumor: Value to Patient Management and Survival Outcomes.
    PET clinics, 2015, Volume: 10, Issue:3

    Topics: Adrenal Gland Neoplasms; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Gallium Radioisotopes; Gast

2015

Other Studies

8 other studies available for dihydroxyphenylalanine and Cancer of Gastrointestinal Tract

ArticleYear
The impact of 18F-FDOPA-PET/MRI image fusion in detecting liver metastasis in patients with neuroendocrine tumors of the gastrointestinal tract.
    BMC medical imaging, 2020, 02-24, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Diffusion Tensor Imaging; Dihydroxyphenylalanine; Female; Gastrointe

2020
18F-FDOPA PET/CT of Nonfunctioning Paraganglioma of the Gastroepiploic Pedicle.
    Clinical nuclear medicine, 2018, Volume: 43, Issue:9

    Topics: Diagnosis, Differential; Dihydroxyphenylalanine; Female; Gastrointestinal Neoplasms; Humans; Mesente

2018
Impact of fluorodihydroxyphenylalanine-18F positron emission tomography on management of adult patients with documented or occult digestive endocrine tumors.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:4

    Topics: Adult; Biopsy; Carcinoid Tumor; Dihydroxyphenylalanine; Endocrine Gland Neoplasms; Fluorodeoxyglucos

2009
Carcinoid crisis after injection of 6-18F-fluorodihydroxyphenylalanine in a patient with metastatic carcinoid.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:7

    Topics: Dihydroxyphenylalanine; Female; Gastrointestinal Neoplasms; Humans; Injections, Intravenous; Liver N

2005
[Gastroenteropancreatic neuroendocrine tumours (carcinoid tumours): definition, clinical aspects, diagnosis and therapy].
    Nederlands tijdschrift voor geneeskunde, 2006, Oct-28, Volume: 150, Issue:43

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Gastrointestinal Neoplasms; Humans; Pancreatic Neoplasms; P

2006
Comparison between 68Ga-DOTA-NOC and 18F-DOPA PET for the detection of gastro-entero-pancreatic and lung neuro-endocrine tumours.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:8

    Topics: Aged; Aged, 80 and over; Dihydroxyphenylalanine; Female; Gastrointestinal Neoplasms; Humans; Lung Ne

2008
Imaging of a metastatic gastrointestinal carcinoid by F-18-DOPA positron emission tomography.
    Nuklearmedizin. Nuclear medicine, 1999, Volume: 38, Issue:4

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Fluorine Radioisotopes; Gastrointestinal Neoplasms; Humans;

1999
Whole-body 18F dopa PET for detection of gastrointestinal carcinoid tumors.
    Radiology, 2001, Volume: 220, Issue:2

    Topics: Adult; Aged; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Fluorodeoxyglu

2001