dihydroxyphenylalanine has been researched along with Brain Neoplasms in 93 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aims of the present study were to: 1- critically assess the utility of L-3,4- dihydroxy-6-18Ffluoro-phenyl-alanine (18F-DOPA) and O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) Positron Emission Tomography (PET)/Computed Tomography (CT) in patients with high grade glioma (HGG) and 2- describe the results of 18F-DOPA and 18F-FET PET/CT in a case series of patients with recurrent HGG." | 5.01 | Comparison Between 18F-Dopa and 18F-Fet PET/CT in Patients with Suspicious Recurrent High Grade Glioma: A Literature Review and Our Experience. ( Bellu, L; Bertin, D; Caccese, M; Cuppari, L; Evangelista, L; Lombardi, G; Reccia, P; Zagonel, V, 2019) |
| "We report the finding of increased F-3,4-dihydroxyphenylalanine uptake of the brain parenchyma adjacent to developmental venous anomalies, incidentally discovered in 3 pediatric patients with diffusely infiltrating gliomas." | 3.83 | 18F-DOPA Uptake of Developmental Venous Anomalies in Children With Brain Tumors. ( Cabria, M; Garrè, ML; Morana, G; Piccardo, A; Rossi, A, 2016) |
| "To compare MRI using perfusion and diffusion techniques with 6-[(18)F]-fluoro-L-3,4-dihydroxyphenylalanine ((18)F-FDOPA) positron emission tomography (PET) in the follow-up of low-grade gliomas (LGGs) and to identify the best imaging parameter to differentiate patients with different prognosis." | 3.83 | Multiparametric evaluation of low grade gliomas at follow-up: comparison between diffusion and perfusion MR with (18)F-FDOPA PET. ( Bozzao, A; Cicone, F; Mancuso, V; Minniti, G; Napolitano, A; Romano, A; Rossi Espagnet, MC; Scaringi, C, 2016) |
| "We assessed the performance of 6-[(18)F]-fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET for differentiating radionecrosis (RN) from tumour progression (PD) in a population of patients with brain metastases, treated with stereotactic radiosurgery." | 3.81 | Accuracy of F-DOPA PET and perfusion-MRI for differentiating radionecrotic from progressive brain metastases after radiosurgery. ( Bozzao, A; Cicone, F; Maurizi Enrici, R; Minniti, G; Papa, A; Romano, A; Scaringi, C; Scopinaro, F; Tavanti, F, 2015) |
| "To compare the diagnostic information obtained with 6-[(18)F]-fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET and relative cerebral blood volume (rCBV) maps in recurrent or progressive glioma." | 3.81 | Volumetric assessment of recurrent or progressive gliomas: comparison between F-DOPA PET and perfusion-weighted MRI. ( Bozzao, A; Cicone, F; Filss, CP; Galldiks, N; Langen, KJ; Minniti, G; Papa, A; Rossi-Espagnet, C; Scaringi, C; Scopinaro, F; Shah, NJ, 2015) |
| "We report the finding of late persistent increased putaminal F-3,4-dihydroxyphenylalanine (DOPA) uptake following resection of a high-grade glioma involving the lateral portion of the ipsilateral precentral gyrus." | 3.81 | Late Persistent Increased Putaminal 18F-DOPA Uptake Following Ipsilateral Frontal Resection: Evidence for Corticostriatal Synaptic Plasticity? ( Garrè, ML; Morana, G; Nobili, F; Piccardo, A; Rossi, A, 2015) |
| "For recurrent malignant glioma treated with bevacizumab and irinotecan, FLT kinetic parameters obtained early after the start of treatment (absolute values and their associated changes) can provide sufficient information to predict OS with reasonable confidence using MLR." | 3.80 | ¹⁸F-FLT and ¹⁸F-FDOPA PET kinetics in recurrent brain tumors. ( Cloughesy, TF; Dahlbom, M; Huang, SC; Phelps, ME; Schiepers, C; Wardak, M, 2014) |
| "Nineteen patients with newly diagnosed high-grade gliomas underwent computed tomography (CT), gadolinium contrast-enhanced MRI, and (18)F-FDOPA PET/CT." | 3.79 | High-grade glioma radiation therapy target volumes and patterns of failure obtained from magnetic resonance imaging and 18F-FDOPA positron emission tomography delineations from multiple observers. ( Benard, F; Chan, EK; Cheung, A; Hsu, F; Kosztyla, R; Ma, R; Moiseenko, V; Nichol, A; Wilson, D; Zhang, S, 2013) |
| "Tc-GH SPECT/CT was positive for recurrence in 22 and negative in 8 patients." | 2.79 | Prospective comparison of (99m)Tc-GH SPECT/CT and (18)F-FDOPA PET/CT for detection of recurrent glioma: a pilot study. ( Bal, C; Bandopadhyaya, GP; Gupta, DK; Karunanithi, S; Kumar, A; Malhotra, A; Sharma, P; Singla, S, 2014) |
| "Differentiation between recurrence and radiation necrosis in patients with glioma is crucial, since the two entities have completely different management and prognosis." | 2.78 | 18F-FDOPA PET/CT for detection of recurrence in patients with glioma: prospective comparison with 18F-FDG PET/CT. ( Bal, C; Bandopadhyaya, GP; Gupta, DK; Karunanithi, S; Khangembam, BC; Kumar, A; Kumar, R; Malhotra, A; Sharma, P, 2013) |
| "Information on evaluation of brain metastases is limited but encouraging." | 2.48 | Molecular imaging of brain tumors with 18F-DOPA PET and PET/CT. ( Calabria, F; Chiaravalloti, A; Di Pietro, B; Grasso, C; Schillaci, O, 2012) |
| "Adult medulloblastoma is extremely rare." | 1.72 | Case of Adult Metastatic Medulloblastoma Demonstrated on 18F-DOPA PET/CT. ( Esmail, A; Marafi, F; Sadeq, A; Usmani, S, 2022) |
| "The power of (18)F-FDOPA PET to predict disease progression was evaluated with the Kaplan-Meier and Cox regression methods." | 1.40 | (18)F-FDOPA PET for differentiating recurrent or progressive brain metastatic tumors from late or delayed radiation injury after radiation treatment. ( Allen-Auerbach, M; Chen, W; Czernin, J; DeSalles, AA; Lizarraga, KJ; Phelps, ME; Yong, WH, 2014) |
| "Here, the kinetics of (18)F-FDOPA in brain tumors were investigated." | 1.34 | 18F-FDOPA kinetics in brain tumors. ( Chen, W; Cloughesy, T; Dahlbom, M; Huang, SC; Schiepers, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (10.75) | 18.7374 |
| 1990's | 3 (3.23) | 18.2507 |
| 2000's | 12 (12.90) | 29.6817 |
| 2010's | 49 (52.69) | 24.3611 |
| 2020's | 19 (20.43) | 2.80 |
| Authors | Studies |
|---|---|
| Marafi, F | 1 |
| Sadeq, A | 1 |
| Esmail, A | 1 |
| Usmani, S | 1 |
| Langen, KJ | 3 |
| Mottaghy, FM | 1 |
| Bertaux, M | 2 |
| Berenbaum, A | 1 |
| Di Stefano, AL | 1 |
| Rozenblum, L | 2 |
| Soret, M | 2 |
| Bergeret, S | 1 |
| Hoang-Xuan, K | 1 |
| Tainturier, LE | 1 |
| Sgard, B | 1 |
| Habert, MO | 1 |
| Delattre, JY | 1 |
| Dehais, C | 1 |
| Idbaih, A | 1 |
| Pyatigorskaya, N | 1 |
| Kas, A | 3 |
| Zaragori, T | 2 |
| Verger, A | 5 |
| Fiz, F | 1 |
| Bini, F | 1 |
| Gabriele, E | 1 |
| Bottoni, G | 2 |
| Garrè, ML | 6 |
| Marinozzi, F | 1 |
| Milanaccio, C | 2 |
| Verrico, A | 2 |
| Massollo, M | 2 |
| Bosio, V | 1 |
| Lattuada, M | 1 |
| Rossi, A | 6 |
| Ramaglia, A | 1 |
| Puntoni, M | 3 |
| Morana, G | 7 |
| Piccardo, A | 7 |
| Breen, WG | 1 |
| Youland, RS | 4 |
| Giri, S | 1 |
| Jacobson, SB | 1 |
| Pafundi, DH | 5 |
| Brown, PD | 1 |
| Hunt, CH | 3 |
| Mahajan, A | 1 |
| Ruff, MW | 1 |
| Kizilbash, SH | 1 |
| Uhm, JH | 1 |
| Routman, DM | 1 |
| Jones, JE | 1 |
| Brinkmann, DH | 5 |
| Laack, NN | 6 |
| Lersy, F | 1 |
| Kremer, S | 2 |
| Chibbaro, S | 2 |
| Namer, IJ | 3 |
| Bund, C | 3 |
| Lakehayli, Z | 1 |
| Phlips, P | 1 |
| Margoum, A | 1 |
| Saoudi, A | 1 |
| Hmaid, L | 1 |
| Nejjar, I | 1 |
| Oueslati, H | 1 |
| Bourgois, N | 1 |
| Dao, S | 1 |
| Belkhir, F | 1 |
| Darcourt, J | 3 |
| Chardin, D | 1 |
| Bourg, V | 1 |
| Gal, J | 1 |
| Schiappa, R | 1 |
| Blonski, M | 2 |
| Koulibaly, PM | 1 |
| Almairac, F | 3 |
| Mondot, L | 1 |
| Le Jeune, F | 1 |
| Collombier, L | 1 |
| Taillandier, L | 2 |
| Todeschi, J | 1 |
| Cebula, H | 1 |
| Lhermitte, B | 2 |
| Pin, Y | 1 |
| Lefebvre, F | 2 |
| Proust, F | 2 |
| Bielle, F | 1 |
| Ollivier, M | 1 |
| Choquet, S | 1 |
| Garcilazo, Y | 1 |
| Mokhtari, K | 2 |
| Cicone, F | 7 |
| Carideo, L | 4 |
| Villani, V | 3 |
| Scaringi, C | 8 |
| Bozzao, A | 5 |
| Scopinaro, F | 6 |
| Minniti, G | 9 |
| Qian, J | 1 |
| Herman, MG | 1 |
| Kemp, BJ | 3 |
| Lowe, V | 2 |
| Castello, A | 1 |
| Guedj, E | 2 |
| Girard, A | 1 |
| Galldiks, N | 3 |
| Albert, NL | 1 |
| Lopci, E | 2 |
| Tatekawa, H | 2 |
| Yao, J | 2 |
| Oughourlian, TC | 2 |
| Hagiwara, A | 2 |
| Wang, C | 1 |
| Raymond, C | 2 |
| Lai, A | 5 |
| Cloughesy, TF | 5 |
| Nghiemphu, PL | 3 |
| Liau, LM | 3 |
| Salamon, N | 2 |
| Ellingson, BM | 4 |
| Romano, A | 3 |
| Mamede, M | 2 |
| Papa, A | 3 |
| Tofani, A | 1 |
| Cascini, GL | 1 |
| Louarn, N | 1 |
| Kauv, P | 1 |
| Capelle, L | 2 |
| Itti, E | 1 |
| Uetani, H | 1 |
| Ueda, I | 1 |
| Bahri, S | 1 |
| Pope, WB | 4 |
| Pafundi, D | 1 |
| Anderson, SK | 1 |
| Kaufmann, T | 1 |
| Hunt, C | 1 |
| Vogen, D | 1 |
| Yan, E | 1 |
| Sarkaria, J | 1 |
| Brown, P | 1 |
| Kizilbash, S | 1 |
| Uhm, J | 1 |
| Ruff, M | 1 |
| Zakhary, M | 1 |
| Zhang, Y | 1 |
| Seaberg, M | 1 |
| Wan Chan Tseung, HS | 1 |
| Kabat, B | 1 |
| Kemp, B | 1 |
| Brinkmann, D | 1 |
| Jena, A | 1 |
| Taneja, S | 1 |
| Khan, AA | 1 |
| Sogani, SK | 1 |
| Dadone-Montaudié, B | 1 |
| Ambrosetti, D | 1 |
| Dufour, M | 2 |
| Coyne, J | 1 |
| Virolle, T | 2 |
| Humbert, O | 1 |
| Burel-Vandenbos, F | 2 |
| Condon, L | 1 |
| Blazak, J | 1 |
| Russo, I | 1 |
| Lowe, VJ | 3 |
| Morris, JM | 2 |
| Giannini, C | 3 |
| Parney, IF | 3 |
| Mancardi, MM | 1 |
| Yu, J | 1 |
| Zheng, J | 1 |
| Xu, W | 1 |
| Weng, J | 1 |
| Gao, L | 1 |
| Tao, L | 1 |
| Liang, F | 1 |
| Zhang, J | 1 |
| Arcella, A | 1 |
| Giangaspero, F | 1 |
| Evangelista, L | 1 |
| Cuppari, L | 1 |
| Bellu, L | 1 |
| Bertin, D | 1 |
| Caccese, M | 1 |
| Reccia, P | 1 |
| Zagonel, V | 1 |
| Lombardi, G | 1 |
| Chiaravalloti, A | 5 |
| Esposito, V | 2 |
| Ursini, F | 1 |
| Di Giorgio, E | 1 |
| Zinzi, M | 2 |
| Calabria, F | 2 |
| Cimini, A | 1 |
| Schillaci, O | 5 |
| Sipos, D | 1 |
| Tóth, Z | 1 |
| Lukács, G | 1 |
| Bajzik, G | 1 |
| Hadjiev, J | 1 |
| Cselik, Z | 1 |
| Repa, I | 1 |
| Kovács, Á | 1 |
| Grams, MP | 1 |
| Hoover, JM | 1 |
| Hu, LS | 1 |
| Sarkaria, JN | 2 |
| Karunanithi, S | 4 |
| Sharma, P | 4 |
| Kumar, A | 4 |
| Khangembam, BC | 3 |
| Bandopadhyaya, GP | 3 |
| Kumar, R | 4 |
| Gupta, DK | 4 |
| Malhotra, A | 3 |
| Bal, C | 4 |
| Singla, S | 1 |
| Goenka, A | 1 |
| Kosztyla, R | 1 |
| Chan, EK | 1 |
| Hsu, F | 1 |
| Wilson, D | 1 |
| Ma, R | 1 |
| Cheung, A | 1 |
| Zhang, S | 1 |
| Moiseenko, V | 1 |
| Benard, F | 1 |
| Nichol, A | 1 |
| Lizarraga, KJ | 2 |
| Allen-Auerbach, M | 1 |
| Czernin, J | 8 |
| DeSalles, AA | 1 |
| Yong, WH | 2 |
| Phelps, ME | 5 |
| Chen, W | 9 |
| Ballal, S | 1 |
| Kratochwil, C | 1 |
| Combs, SE | 1 |
| Leotta, K | 1 |
| Afshar-Oromieh, A | 1 |
| Rieken, S | 1 |
| Debus, J | 1 |
| Haberkorn, U | 1 |
| Giesel, FL | 1 |
| Wardak, M | 1 |
| Schiepers, C | 4 |
| Dahlbom, M | 2 |
| Huang, SC | 2 |
| Nozza, P | 2 |
| Cama, A | 1 |
| Zefiro, D | 1 |
| Cabria, M | 2 |
| Schwarzenberg, J | 1 |
| Grogan, T | 1 |
| Elashoff, D | 1 |
| Geist, C | 1 |
| Silverman, DH | 4 |
| De Salles, AA | 1 |
| Pretze, M | 1 |
| Wängler, C | 1 |
| Wängler, B | 1 |
| Lapa, C | 1 |
| Linsenmann, T | 1 |
| Monoranu, CM | 1 |
| Samnick, S | 1 |
| Buck, AK | 1 |
| Bluemel, C | 1 |
| Kessler, AF | 1 |
| Homola, GA | 1 |
| Ernestus, RI | 1 |
| Löhr, M | 1 |
| Herrmann, K | 1 |
| Tavanti, F | 1 |
| Maurizi Enrici, R | 1 |
| Karavaeva, E | 1 |
| Harris, RJ | 1 |
| Leu, K | 1 |
| Shabihkhani, M | 1 |
| Fiorentini, A | 1 |
| Carapella, C | 1 |
| Pace, A | 2 |
| Di Pietro, B | 2 |
| Di Russo, C | 1 |
| Palumbo, B | 1 |
| Floris, R | 2 |
| Filss, CP | 1 |
| Rossi-Espagnet, C | 1 |
| Shah, NJ | 1 |
| Nobili, F | 1 |
| Janvier, L | 1 |
| Olivier, P | 1 |
| Morel, O | 1 |
| Vignaud, JM | 1 |
| Karcher, G | 1 |
| Carapella, CM | 1 |
| Terrenato, I | 1 |
| Piludu, F | 1 |
| Vidiri, A | 1 |
| Marzi, S | 1 |
| Fabi, A | 1 |
| Wartski, M | 1 |
| Jehanno, N | 1 |
| Michon, J | 1 |
| de Labriolle-Vaylet, C | 1 |
| Montravers, F | 2 |
| Naseri, M | 1 |
| Severino, M | 1 |
| Tortora, D | 1 |
| Papin-Michault, C | 1 |
| Bonnetaud, C | 1 |
| Coutts, M | 1 |
| Patouraux, S | 1 |
| Calabria, FF | 1 |
| Jaffrain-Rea, ML | 1 |
| Sannino, P | 1 |
| Rubello, D | 1 |
| Rossi Espagnet, MC | 1 |
| Mancuso, V | 1 |
| Napolitano, A | 1 |
| Heimburger, C | 1 |
| Imperiale, A | 1 |
| Chenard, MP | 1 |
| Law, I | 1 |
| Arbizu, J | 1 |
| Metellus, P | 1 |
| Sala, Q | 1 |
| Colin, C | 1 |
| Bialecki, E | 1 |
| Taieb, D | 1 |
| Chinot, O | 1 |
| Figarella-Branger, D | 1 |
| Ledezma, CJ | 1 |
| Sai, V | 1 |
| Freitas, B | 1 |
| Cloughesy, T | 5 |
| Pope, W | 2 |
| Fischman, AJ | 1 |
| Alheit, H | 1 |
| Oehme, L | 1 |
| Winkler, C | 1 |
| Füchtner, F | 2 |
| Hoepping, A | 1 |
| Grabowski, J | 1 |
| Kotzerke, J | 2 |
| Beuthien-Baumann, B | 2 |
| Tripathi, M | 1 |
| Sharma, R | 1 |
| D'Souza, M | 1 |
| Jaimini, A | 1 |
| Panwar, P | 1 |
| Varshney, R | 1 |
| Datta, A | 1 |
| Kumar, N | 1 |
| Garg, G | 1 |
| Singh, D | 1 |
| Grover, RK | 1 |
| Mishra, AK | 1 |
| Mondal, A | 1 |
| Fueger, BJ | 1 |
| Geist, CL | 1 |
| Walter, MA | 2 |
| Nghiemphu, P | 2 |
| Dowson, N | 1 |
| Bourgeat, P | 1 |
| Rose, S | 1 |
| Daglish, M | 1 |
| Smith, J | 1 |
| Fay, M | 1 |
| Coulthard, A | 1 |
| Winter, C | 1 |
| MacFarlane, D | 1 |
| Thomas, P | 1 |
| Crozier, S | 1 |
| Salvado, O | 1 |
| Walter, F | 1 |
| Wagle, N | 1 |
| Fueger, B | 1 |
| Satyamurthy, N | 2 |
| Grasso, C | 1 |
| Kitange, GJ | 1 |
| Peterson, TE | 1 |
| Ramiscal, JA | 1 |
| Pokorny, JL | 1 |
| De Sanctis, V | 1 |
| Lanzetta, G | 1 |
| Falco, T | 1 |
| Di Stefano, D | 1 |
| Enrici, RM | 1 |
| Consales, A | 1 |
| Nioche, C | 1 |
| Gontier, E | 1 |
| Lahutte, M | 1 |
| Dutertre, G | 1 |
| Dulou, R | 1 |
| Guillevin, R | 1 |
| Foehrenbach, H | 1 |
| Buvat, I | 1 |
| Bredow, J | 1 |
| Burchert, W | 1 |
| Bergmann, R | 1 |
| Alheit, HD | 1 |
| Reiss, G | 1 |
| Hliscs, R | 1 |
| Steinmeier, R | 1 |
| Franke, WG | 1 |
| Johannsen, B | 1 |
| Pimpinelli, F | 1 |
| Redaelli, E | 1 |
| Restano-Cassulini, R | 1 |
| Curia, G | 1 |
| Giacobini, P | 1 |
| Cariboni, A | 1 |
| Wanke, E | 1 |
| Bondiolotti, GP | 1 |
| Piva, F | 1 |
| Maggi, R | 1 |
| Becherer, A | 1 |
| Karanikas, G | 1 |
| Szabó, M | 1 |
| Zettinig, G | 1 |
| Asenbaum, S | 1 |
| Marosi, C | 1 |
| Henk, C | 1 |
| Wunderbaldinger, P | 1 |
| Czech, T | 1 |
| Wadsak, W | 1 |
| Kletter, K | 1 |
| Delaloye, S | 1 |
| Kamdar, N | 1 |
| Talbot, JN | 1 |
| Kerrou, K | 1 |
| Gault, N | 1 |
| Gutman, F | 1 |
| Grahek, D | 1 |
| Touboul, E | 1 |
| Schlienger, M | 1 |
| Makrides, V | 1 |
| Bauer, R | 1 |
| Weber, W | 1 |
| Wester, HJ | 1 |
| Fischer, S | 1 |
| Hinz, R | 1 |
| Huggel, K | 1 |
| Opfermann, T | 1 |
| Herzau, M | 1 |
| Ganapathy, V | 1 |
| Verrey, F | 1 |
| Brust, P | 1 |
| Seibyl, JP | 1 |
| Jönsson, PE | 1 |
| Agrup, G | 1 |
| Arnbjörnsson, E | 1 |
| Hafström, L | 1 |
| Rorsman, H | 1 |
| Helson, L | 1 |
| Johnson, GA | 1 |
| Smith, R | 1 |
| Ikeda, H | 1 |
| Matsuyama, S | 1 |
| Suzuki, N | 1 |
| Takahashi, A | 1 |
| Kuroiwa, M | 1 |
| Heiss, WD | 1 |
| Wienhard, K | 1 |
| Wagner, R | 1 |
| Lanfermann, H | 1 |
| Thiel, A | 1 |
| Herholz, K | 1 |
| Pietrzyk, U | 1 |
| Lelong, IH | 1 |
| Rebel, G | 1 |
| Boyar, RM | 1 |
| Kapen, S | 1 |
| Finkelstein, JW | 1 |
| Perlow, M | 1 |
| Sassin, JF | 1 |
| Fukushima, DK | 1 |
| Weitzman, ED | 1 |
| Hellman, L | 1 |
| Stellar, S | 1 |
| Cooper, IS | 1 |
| Griffith, D | 1 |
| Narotzky, R | 1 |
| McLone, D | 1 |
| Turkington, RW | 1 |
| Goldstein, M | 1 |
| Paini, GP | 1 |
| Passoni, M | 1 |
| Narabayashi, H | 1 |
| Greer, M | 1 |
| Anton, AH | 1 |
| Williams, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating the Impact of 18F-DOPA-PET on Radiotherapy Planning for Newly Diagnosed Gliomas[NCT01991977] | Phase 2 | 91 participants (Actual) | Interventional | 2013-12-31 | Active, not recruiting | ||
| Evaluation of 18F-Fluciclovine PET-MRI to Differentiate Tumor Progression From Post-treatment Changes in Pediatric High-grade Glioma (HGG)[NCT05553041] | Early Phase 1 | 30 participants (Anticipated) | Interventional | 2023-08-07 | Recruiting | ||
| Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)[NCT05555550] | Early Phase 1 | 30 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| A Phase II Study of Hypofractionated Stereotactic Radiotherapy Combined With Anlotinib in Patients With Recurrent High-Grade Glioma[NCT04197492] | Phase 2 | 32 participants (Anticipated) | Interventional | 2019-12-16 | Recruiting | ||
| Imaging After Stereotactic Radiosurgery for Brain Metastases or Primary Tumor Can Hybrid PET-MRI Differentiate Between Radiation Effects and Disease ?[NCT03068520] | 140 participants (Anticipated) | Interventional | 2017-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The proportion of Grade IV MGMT un-methylated patients that experience confirmed-progression-free survival at 6 months (CPFS6). Progression is defined by any of the following:~≥25% increase in the sum of products of perpendicular diameters of enhancing lesions compared to the smallest tumor measurement obtained either at baseline or best response, on stable or increasing doses of corticosteroids~Significant increase in T2/FLAIR non-enhancing lesion on stable or increasing doses of corticosteroids compared to baseline scan or best response following initiation of therapy, not due to co-morbid events~Any new lesion~Clear clinical deterioration not attributable to other causes apart from the tumor or changes in corticosteroid dose.~Failure to return for evaluation due to death or deteriorating condition~Clear progression of non-measurable disease" (NCT01991977)
Timeframe: Time from registration to the confirmed disease progression, assessed at 6 months
| Intervention | proportion of participants (Number) |
|---|---|
| Diagnostic (PET, pMRI, DTI, IMRT, Temozolomide) | 0.795 |
10 reviews available for dihydroxyphenylalanine and Brain Neoplasms
| Article | Year |
|---|---|
Accuracy of
Topics: Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Neoplasm Recurrence, Local | 2018 |
Comparison Between 18F-Dopa and 18F-Fet PET/CT in Patients with Suspicious Recurrent High Grade Glioma: A Literature Review and Our Experience.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Neoplasm Recurrence, Local; Positron Emissi | 2019 |
6-[18F]fluoro-L-DOPA: a well-established neurotracer with expanding application spectrum and strongly improved radiosyntheses.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Humans; Mental Disorders; Movement Disorders; Radioactive T | 2014 |
The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy.
Topics: Amino Acids; Brain Neoplasms; Dihydroxyphenylalanine; Humans; Methionine; Positron-Emission Tomograp | 2017 |
The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy.
Topics: Amino Acids; Brain Neoplasms; Dihydroxyphenylalanine; Humans; Methionine; Positron-Emission Tomograp | 2017 |
The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy.
Topics: Amino Acids; Brain Neoplasms; Dihydroxyphenylalanine; Humans; Methionine; Positron-Emission Tomograp | 2017 |
The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy.
Topics: Amino Acids; Brain Neoplasms; Dihydroxyphenylalanine; Humans; Methionine; Positron-Emission Tomograp | 2017 |
PET imaging of brain tumors.
Topics: Biopsy; Brain; Brain Neoplasms; Cell Proliferation; Diagnostic Imaging; Dihydroxyphenylalanine; Fluo | 2008 |
Molecular imaging of brain tumors with 18F-DOPA PET and PET/CT.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; | 2012 |
[PET and malignant cerebral tumors].
Topics: Brain Neoplasms; Choline; Dideoxynucleosides; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Glioma | 2006 |
3,4-dihydroxy-6-[18f]-fluoro-L-phenylalanine positron emission tomography in patients with central motor disorders and in evaluation of brain and other tumors.
Topics: Adrenal Gland Neoplasms; Amino Acids; Brain Neoplasms; Caudate Nucleus; Dihydroxyphenylalanine; Fluo | 2007 |
The clinical endocrinology of prolactin.
Topics: Amenorrhea; Biological Assay; Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Fema | 1972 |
Brain research and violent behavior. A summary and evaluation of the status of biomedical research on brain and aggressive violent behavior.
Topics: Aggression; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Bipolar Disorder; Bra | 1974 |
10 trials available for dihydroxyphenylalanine and Brain Neoplasms
| Article | Year |
|---|---|
Initial results of a phase II trial of
Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Magnetic Resonance Imaging; Neoplasm | 2022 |
Initial Results of a Phase 2 Trial of
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunologi | 2021 |
[18F] FDOPA standardized uptake values of brain tumors are not exclusively dependent on LAT1 expression.
Topics: Adult; Aged; Amino Acid Transport Systems, Basic; Brain; Brain Neoplasms; Dihydroxyphenylalanine; Fe | 2017 |
Prospective trial evaluating the sensitivity and specificity of 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (18F-DOPA) PET and MRI in patients with recurrent gliomas.
Topics: Adolescent; Adult; Brain; Brain Neoplasms; Contrast Media; Dihydroxyphenylalanine; Female; Glioma; H | 2018 |
18F-FDOPA PET/CT for detection of recurrence in patients with glioma: prospective comparison with 18F-FDG PET/CT.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; G | 2013 |
Prospective comparison of (99m)Tc-GH SPECT/CT and (18)F-FDOPA PET/CT for detection of recurrent glioma: a pilot study.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Male; Multimodal Imaging; Organotec | 2014 |
Factors affecting ¹⁸F FDOPA standardized uptake value in patients with primary brain tumors after treatment.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Brain Neoplasms; Dihydroxyphenylalanine; Femal | 2015 |
3-O-methyl-6-[18F]fluoro-L-DOPA and its evaluation in brain tumour imaging.
Topics: Adult; Aged; Body Burden; Brain Neoplasms; Dihydroxyphenylalanine; Female; Humans; Male; Metabolic C | 2003 |
Brain tumour imaging with PET: a comparison between [18F]fluorodopa and [11C]methionine.
Topics: Adult; Aged; Brain Neoplasms; Dihydroxyphenylalanine; Female; Humans; Male; Methionine; Middle Aged; | 2003 |
18F-FDOPA PET imaging of brain tumors: comparison study with 18F-FDG PET and evaluation of diagnostic accuracy.
Topics: Adult; Aged; Brain Neoplasms; California; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Hu | 2006 |
73 other studies available for dihydroxyphenylalanine and Brain Neoplasms
| Article | Year |
|---|---|
Case of Adult Metastatic Medulloblastoma Demonstrated on 18F-DOPA PET/CT.
Topics: Adult; Brain Neoplasms; Cerebellar Neoplasms; Dihydroxyphenylalanine; Humans; Male; Medulloblastoma; | 2022 |
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Neoplasm Recurrence, Local; Positron-Emissi | 2022 |
Hybrid [
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Follow-Up Studies; Glioma; Humans; Magnetic Resonance Imagi | 2022 |
Reply:
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Positron-Emission Tomography | 2022 |
Role of Dynamic Parameters of 18F-DOPA PET/CT in Pediatric Gliomas.
Topics: Brain Neoplasms; Child; Dihydroxyphenylalanine; Glioma; Humans; Positron Emission Tomography Compute | 2022 |
18 F-FDOPA and MRI Findings in a Case of Multiple Sclerosis.
Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Humans; Magnetic Res | 2022 |
What effective technique to differentiate radiation brain necrosis from a tumor progression in patients treated with radiation: A monocentric retrospective study combining the MRI TRAMs technique and the (
Topics: Brain; Brain Neoplasms; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Necrosis; Neopla | 2023 |
Added value of [
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Neoplasm Recurrence, Local; Positron-Emissi | 2023 |
Diagnostic value of fusion of metabolic and structural images for stereotactic biopsy of brain tumors without enhancement after contrast medium injection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Brain Neoplasms; Child; Contrast Media; Dihydrox | 2019 |
18F-FDOPA PET/CT Findings in a Patient With Primary Cerebral Amyloidoma.
Topics: Aged; Amyloidosis; Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Glioma; | 2020 |
Metabolic Evolution of Brain Metastasis After Stereotactic Radiosurgery: Mismatch Between F-DOPA and FDG PET.
Topics: Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Hu | 2020 |
Prediction of MGMT Status for Glioblastoma Patients Using Radiomics Feature Extraction From
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Brain Neoplasms; Dihydroxyphenylalanine; DNA Modificatio | 2020 |
Photopenic Defects in Gliomas With Amino-Acid PET and Relative Prognostic Value: A Multicentric 11C-Methionine and 18F-FDOPA PET Experience.
Topics: Adult; Aged; Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Male; Methionine; Midd | 2021 |
Maximum Uptake and Hypermetabolic Volume of 18F-FDOPA PET Estimate Molecular Status and Overall Survival in Low-Grade Gliomas: A PET and MRI Study.
Topics: Adult; Biological Transport; Brain Neoplasms; Diffusion Magnetic Resonance Imaging; Dihydroxyphenyla | 2020 |
Long-term metabolic evolution of brain metastases with suspected radiation necrosis following stereotactic radiosurgery: longitudinal assessment by F-DOPA PET.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Humans; Necrosis; Positron Emission Tomography Computed Tom | 2021 |
Illustration of the Added Value of 18F-DOPA PET to Multimodal MRI to Distinguish Low- and High-Grade Gliomas.
Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Magnetic Resonance Imaging; Male; Mu | 2021 |
Preferential tumor localization in relation to
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Isocitrate Dehydrogenase; Neoplasm Grading; | 2021 |
Recurrent Glioma: Does Qualitative Simultaneous 18F-DOPA PET/mp-MRI Improve Diagnostic Workup? An Initial Experience.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Magnetic Resonance Imaging; Multiparametric | 2021 |
Focal 18F-DOPA Uptake in Brain Parenchyma Surrounding Developmental Venous Anomalies.
Topics: Biological Transport; Brain; Brain Neoplasms; Dihydroxyphenylalanine; Female; Humans; Middle Aged; P | 2018 |
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine; Female; Gli | 2018 |
Seizure-Induced Increased 18F-DOPA Uptake in a Child With Diffuse Astrocytoma and Transient Brain MRI Abnormalities Related to Status Epilepticus.
Topics: Astrocytoma; Brain; Brain Neoplasms; Child, Preschool; Dihydroxyphenylalanine; Humans; Magnetic Reso | 2018 |
Topics: Biological Transport; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, | 2019 |
Overall survival and progression-free survival in patients with primary brain tumors after treatment: is the outcome of [
Topics: Adult; Brain Neoplasms; Cohort Studies; Dihydroxyphenylalanine; Female; Humans; Male; Positron Emiss | 2019 |
[F-DOPA PET/MR based target definiton in the 3D based radiotherapy treatment of glioblastoma multiforme patients. First Hungarian experiences].
Topics: Brain Neoplasms; Cross-Sectional Studies; Dihydroxyphenylalanine; Glioblastoma; Humans; Hungary; Mag | 2019 |
Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study.
Topics: Adult; Aged; Brain Neoplasms; Dihydroxyphenylalanine; Female; Follow-Up Studies; Glioma; Humans; Imm | 2013 |
Comparative diagnostic accuracy of contrast-enhanced MRI and (18)F-FDOPA PET-CT in recurrent glioma.
Topics: Adult; Brain Neoplasms; Contrast Media; Dihydroxyphenylalanine; Female; Glioma; Humans; Image Proces | 2013 |
High-grade glioma radiation therapy target volumes and patterns of failure obtained from magnetic resonance imaging and 18F-FDOPA positron emission tomography delineations from multiple observers.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Contrast Media; Dihydroxyphenylalanine; Female; Fluorine | 2013 |
(18)F-FDOPA PET for differentiating recurrent or progressive brain metastatic tumors from late or delayed radiation injury after radiation treatment.
Topics: Adult; Aged; Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Disease Progression; | 2014 |
Can (18)F-FDOPA PET/CT predict survival in patients with suspected recurrent glioma? A prospective study.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Dihydroxyphenylalanine; Female; Glioma; Humans; India; Ma | 2014 |
Intra-individual comparison of ¹⁸F-FET and ¹⁸F-DOPA in PET imaging of recurrent brain tumors.
Topics: Astrocytoma; Brain Neoplasms; Dihydroxyphenylalanine; Glioblastoma; Humans; Neoplasm Recurrence, Loc | 2014 |
¹⁸F-FLT and ¹⁸F-FDOPA PET kinetics in recurrent brain tumors.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasm | 2014 |
Value of 18F-3,4-dihydroxyphenylalanine PET/MR image fusion in pediatric supratentorial infiltrative astrocytomas: a prospective pilot study.
Topics: Adolescent; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Child; Dihydroxyphenylalanine; Disease | 2014 |
Treatment response evaluation using 18F-FDOPA PET in patients with recurrent malignant glioma on bevacizumab therapy.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Anti | 2014 |
¹⁸F-fluorodopa positron-emission tomography: an emerging imaging modality for patients with brain metastases.
Topics: Biopsy; Brain Neoplasms; Dihydroxyphenylalanine; Disease Progression; Humans; Neoplasm Recurrence, L | 2014 |
Comparison of the amino acid tracers 18F-FET and 18F-DOPA in high-grade glioma patients.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Basal Ganglia; Biopsy; Brain; Brain Neoplasms; Dihydrox | 2014 |
Accuracy of F-DOPA PET and perfusion-MRI for differentiating radionecrotic from progressive brain metastases after radiosurgery.
Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Fe | 2015 |
Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas.
Topics: Adult; Aged; Brain Neoplasms; Cell Proliferation; Contrast Media; Diffusion; Dihydroxyphenylalanine; | 2015 |
Volumetric assessment of recurrent or progressive gliomas: comparison between F-DOPA PET and perfusion-weighted MRI.
Topics: Adult; Aged; Brain Neoplasms; Cone-Beam Computed Tomography; Dihydroxyphenylalanine; Female; Glioma; | 2015 |
Late Persistent Increased Putaminal 18F-DOPA Uptake Following Ipsilateral Frontal Resection: Evidence for Corticostriatal Synaptic Plasticity?
Topics: Adolescent; Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Male; Neuronal Plasticity; Puta | 2015 |
Correlation of SUV-Derived Indices With Tumoral Aggressiveness of Gliomas in Static 18F-FDOPA PET: Use in Clinical Practice.
Topics: Adult; Aged; Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Male; Middle Aged; Pos | 2015 |
The Role of PET [18F]FDOPA in Evaluating Low-grade Glioma.
Topics: Adult; Aged; Brain Neoplasms; Demography; Dihydroxyphenylalanine; Disease Progression; Female; Fluor | 2015 |
Weak uptake of 123I-MIBG and 18F-FDOPA contrasting with high 18F-FDG uptake in stage I neuroblastoma.
Topics: 3-Iodobenzylguanidine; Brain Neoplasms; Child; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F1 | 2015 |
18F-DOPA Uptake of Developmental Venous Anomalies in Children With Brain Tumors.
Topics: Brain; Brain Neoplasms; Child; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Glioma; Humans; Magne | 2016 |
Ability of (18)F-DOPA PET/CT and fused (18)F-DOPA PET/MRI to assess striatal involvement in paediatric glioma.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Dihydroxyphenylalanine; False Negative Reactio | 2016 |
Study of LAT1 Expression in Brain Metastases: Towards a Better Understanding of the Results of Positron Emission Tomography Using Amino Acid Tracers.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Female; Gene Expression Regulation, Neoplastic; Humans; Lar | 2016 |
18F-DOPA PET/CT Physiological Distribution and Pitfalls: Experience in 215 Patients.
Topics: Adult; Aged; Biological Transport; Brain Neoplasms; Dihydroxyphenylalanine; Female; Fluorine Radiois | 2016 |
Multiparametric evaluation of low grade gliomas at follow-up: comparison between diffusion and perfusion MR with (18)F-FDOPA PET.
Topics: Adult; Aged; Brain Neoplasms; Diffusion Magnetic Resonance Imaging; Dihydroxyphenylalanine; Female; | 2016 |
FDOPA PET-CT of Nonenhancing Brain Tumors.
Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Magnetic Resonance Imaging; | 2017 |
IDH mutation is paradoxically associated with higher
Topics: Adult; Biological Transport; Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Isocit | 2017 |
18F-FDOPA PET/MRI fusion in patients with primary/recurrent gliomas: initial experience.
Topics: Adult; Aged; Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Image Enhancement; Mag | 2009 |
Radiation treatment planning in brain tumours: potential impact of 3-O-methyl-6-[(18)F]fluoro-L-DOPA and PET.
Topics: Biopsy; Brain Neoplasms; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Glioma; Humans; Mag | 2008 |
Comparative evaluation of F-18 FDOPA, F-18 FDG, and F-18 FLT-PET/CT for metabolic imaging of low grade gliomas.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Dideoxynucleosides; Dihydroxyphenylalan | 2009 |
Correlation of 6-18F-fluoro-L-dopa PET uptake with proliferation and tumor grade in newly diagnosed and recurrent gliomas.
Topics: Adult; Aged; Brain Neoplasms; Dihydroxyphenylalanine; Glioma; Humans; Male; Middle Aged; Neoplasm Re | 2010 |
Joint factor and kinetic analysis of dynamic FDOPA PET scans of brain cancer patients.
Topics: Algorithms; Brain Neoplasms; Computer Simulation; Dihydroxyphenylalanine; Factor Analysis, Statistic | 2010 |
Impact of 3,4-dihydroxy-6-18F-fluoro-L-phenylalanine PET/CT on managing patients with brain tumors: the referring physician's perspective.
Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Dihydroxyphenylalanine; Female; Follow | 2012 |
The role of LAT1 in (18)F-DOPA uptake in malignant gliomas.
Topics: Animals; Biological Transport; Blotting, Western; Brain Neoplasms; Dihydroxyphenylalanine; Fluoresce | 2013 |
Hypofractionated stereotactic radiotherapy and continuous low-dose temozolomide in patients with recurrent or progressive malignant gliomas.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine | 2013 |
Multimodal magnetic resonance imaging and 18F-L-dihydroxyphenylalanine positron emission tomography in early characterization of pseudoresponse and nonenhancing tumor progression in a pediatric patient with malignant transformation of ganglioglioma treate
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai | 2013 |
Evaluation of quantitative criteria for glioma grading with static and dynamic 18F-FDopa PET/CT.
Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Dihydroxyphenylalanine; Female; Glioma; Humans; Ima | 2013 |
Depolarization differentially affects the secretory and migratory properties of two cell lines of immortalized luteinizing hormone-releasing hormone (LHRH) neurons.
Topics: Anesthetics, Local; Animals; Biogenic Monoamines; Brain Neoplasms; Calcium Channel Blockers; Cell Cu | 2003 |
Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain.
Topics: Adult; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Neoplasms; Contrast Media; D | 2007 |
18F-FDOPA kinetics in brain tumors.
Topics: Adult; Aged; Brain; Brain Neoplasms; Computer Simulation; Dihydroxyphenylalanine; Female; Humans; Im | 2007 |
Treatment of malignant melanoma with dacarbazin (DTIC-DOME) with special reference to urinary excretion of 5-S-cysteinyldopa.
Topics: Adult; Aged; Brain Neoplasms; Cysteinyldopa; Dacarbazine; Digestive System; Dihydroxyphenylalanine; | 1980 |
DOPA metabolism in neuroblastoma.
Topics: Adolescent; Bone Neoplasms; Brain Neoplasms; Child; Dihydroxyphenylalanine; False Negative Reactions | 1980 |
3,4-dihydroxyphenylalanine (DOPA) decarboxylase deficiency and resultant high levels of plasma DOPA and dopamine in unfavorable neuroblastoma.
Topics: Biomarkers, Tumor; Brain Neoplasms; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Humans; Ne | 1995 |
F-Dopa as an amino acid tracer to detect brain tumors.
Topics: Brain; Brain Neoplasms; Deoxyglucose; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Fluoro | 1996 |
pH drift of "physiological buffers" and culture media used for cell incubation during in vitro studies.
Topics: Bicarbonates; Brain Neoplasms; Buffers; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Di | 1998 |
Hypothalamic-pituitary function in diverse hyperprolactinemic states.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Brain Neoplasms; Dihydroxyphenylalanine; Erectile Dysf | 1974 |
Recent advances in neurosurgical treatment for the elderly.
Topics: Aged; Animals; Brain Neoplasms; Cats; Central Nervous System Diseases; Cerebral Angiography; Cryosur | 1970 |
Effect of L-DOPA on motor behavior in a rat with a unilateral striatal neoplasm.
Topics: Animals; Basal Ganglia; Behavior, Animal; Brain Neoplasms; Caudate Nucleus; Corpus Striatum; Dihydro | 1972 |
[Results obtained with L-DOPA and amantadine in the treatment of patients with disorders of consciousness and of the vigilant state].
Topics: Adult; Aged; Amantadine; Attention; Brain Diseases; Brain Injuries; Brain Neoplasms; Cognition Disor | 1973 |
[Present status and future problems of stereoencephalotomy].
Topics: Athetosis; Brain; Brain Neoplasms; Chorea; Dihydroxyphenylalanine; Epilepsy; Humans; Myoclonus; Park | 1971 |
Failure of enzyme inhibition therapy for malignant melanoma.
Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Dopamine; Enzyme Repression; Epinephrine; Humans; Ma | 1969 |