dihydroxyphenylalanine has been researched along with Blood Pressure, Low in 65 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Excerpt | Relevance | Reference |
---|---|---|
" All patients entering the trial were taking anticholinergic drugs in stable dosage and these were continued throughout." | 2.64 | L-dopa in Parkinsonism and the influence of previous thalamotomy. ( Hughes, RC; Polgar, JG; Walton, JN; Weightman, D, 1971) |
"The blood pressure and pulse rate have been compared in a 'double blind, cross over' study involving twenty patients with idiopathic Parkinsonism receiving maximum tolerated dosage of levodopa with and without an extracerebral decarboxylase inhibitor, L-alpha-methyldopahydrazine." | 2.64 | Action of L- -methyldopa-hydrazine on the blood pressure of patients receiving levodopa. ( Calne, DB; Petrie, A; Rao, S; Reid, JL; Vakil, SD, 1972) |
"One problem with DOPA therapy for Parkinson's disease is its cardiovascular side effects including hypotension and syncope, the underlying mechanisms of which are largely unknown." | 2.50 | Cardiovascular actions of DOPA mediated by the gene product of ocular albinism 1. ( Chen, S; Goshima, Y; Koga, M; Masukawa, D; Nakamura, F, 2014) |
"Heatstroke was induced by exposing the anesthetized rabbits to a high blanket temperature (T(blanket)) of 45 degrees C." | 1.33 | Dopamine overload visualized in the basal ganglia of rabbit brain during heatstroke can be suppressed by hypothermia. ( Chang, CW; Chen, JC; Chou, KL; Chou, YT; Lin, MT; Liu, RS, 2005) |
"Nausea and cardiac arrhythmias are lessened, as are the incidence and severity of hypotension." | 1.25 | Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease. ( Barbeau, A; Botez, MI; Joubert, M; Mars, H, 1972) |
"Low blood pressure is frequent in the akinetic form of Parkinson's disease." | 1.25 | Renin-aldosterone system in Parkinson's disease. ( Barbeau, A; Boucher, R; Genest, J; Gillo-Joffroy, L; Nowaczynski, W, 1969) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 62 (95.38) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (3.08) | 29.6817 |
2010's | 1 (1.54) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Goshima, Y | 1 |
Nakamura, F | 1 |
Masukawa, D | 1 |
Chen, S | 1 |
Koga, M | 1 |
PERRICONI, H | 1 |
DEL RIO, CA | 1 |
MAZZEI, CM | 1 |
SCHAER, H | 1 |
ZIEGLER, WH | 1 |
ALEKSANDROW, D | 1 |
JANUSZEWICZ, W | 1 |
WOCIAL, B | 1 |
SCHMITT, H | 2 |
Lu, CC | 1 |
Diedrich, A | 1 |
Tung, CS | 1 |
Paranjape, SY | 1 |
Harris, PA | 1 |
Byrne, DW | 1 |
Jordan, J | 1 |
Robertson, D | 2 |
Chou, YT | 1 |
Chen, JC | 1 |
Liu, RS | 1 |
Chou, KL | 1 |
Chang, CW | 1 |
Lin, MT | 1 |
Man'shikov, VV | 1 |
Rudoĭ, BD | 1 |
Bol'shakova, TD | 1 |
Shekhter, IM | 1 |
Lukicheva, TI | 1 |
Conlay, LA | 1 |
Maher, TJ | 1 |
Godley, BF | 1 |
Wurtman, RJ | 1 |
Hunter, KR | 2 |
Stern, GM | 3 |
Laurence, DR | 1 |
Glogner, P | 1 |
Fazio, C | 1 |
Agnoli, A | 1 |
Casacchia, M | 1 |
Reitano, M | 1 |
Ruggieri, S | 1 |
Barba, C | 1 |
Volante, F | 1 |
Desjacques, P | 1 |
Moret, P | 1 |
Gauthier, G | 2 |
Godwin-Austen, RB | 2 |
Lind, NA | 1 |
Turner, P | 1 |
Frears, CC | 1 |
Bergmann, S | 1 |
Parkes, JD | 1 |
Knill-Jones, RP | 1 |
Robson, RD | 1 |
Bolme, P | 1 |
Fuxe, K | 1 |
Lidbrink, P | 1 |
Boudin, G | 1 |
Pépin, B | 1 |
Guillard, A | 2 |
Fabiani, JM | 1 |
Haguenau, M | 1 |
Völler, GW | 1 |
Muschard, F | 1 |
Wälzholz, U | 1 |
Boshes, B | 1 |
Iisalo, E | 1 |
Vetrova, LP | 1 |
Studnitsyna, LA | 1 |
Frenkel', ID | 2 |
Groneberg, P | 1 |
Struppler, A | 1 |
Bevan, DR | 1 |
Monks, PS | 1 |
Calne, DB | 3 |
Schneider, E | 1 |
Fischer, PA | 1 |
Jacobi, P | 1 |
Maxion, H | 1 |
Battista, AF | 1 |
Wolff, BB | 1 |
Hirschmann, J | 1 |
Sutcliffe, RL | 1 |
Brennan, J | 1 |
Spiers, AS | 1 |
Hughes, RC | 1 |
Polgar, JG | 1 |
Weightman, D | 1 |
Walton, JN | 1 |
Finlay, GD | 1 |
Whitsett, TL | 1 |
Cucinell, EA | 1 |
Goldberg, LI | 1 |
Rinne, UK | 1 |
Sonninen, V | 1 |
Siirtola, T | 1 |
Reef, HE | 1 |
Joffe, R | 1 |
Milletz, H | 1 |
Weiss, JL | 1 |
Chase, TN | 1 |
Petrie, A | 1 |
Rao, S | 1 |
Reid, JL | 1 |
Vakil, SD | 1 |
Barbeau, A | 3 |
Mars, H | 2 |
Botez, MI | 1 |
Joubert, M | 1 |
Libman, I | 1 |
Schwartz, AM | 1 |
Gillo-Joffroy, L | 2 |
MacIntyre, IM | 1 |
Strange, DM | 1 |
Beavis, JP | 1 |
Reveno, WS | 1 |
Bauer, RB | 1 |
Rosenbaum, H | 1 |
Guidetti, B | 1 |
Giuffrè, R | 1 |
Jenkins, AC | 1 |
Schwieger, AC | 1 |
O'Doherty, DS | 1 |
Skobba, TJ | 1 |
Newkirk, TA | 1 |
Magee, KR | 1 |
Düby, SE | 1 |
Dahl, LK | 1 |
Cotzias, GC | 1 |
Hashimoto, Y | 1 |
Lydtin, H | 1 |
Klawans, HL | 1 |
Garvin, JS | 1 |
Mones, RJ | 1 |
Duvoisin, RC | 2 |
Burn, JH | 1 |
McDowell, FH | 1 |
Lee, JE | 1 |
Shanks, RG | 1 |
Michelakis, AM | 1 |
Siegfried, J | 1 |
Landy, PJ | 1 |
Whitnack, E | 1 |
Leff, A | 1 |
Mohammed, S | 1 |
Gaffney, TE | 1 |
Jelsma, F | 1 |
Roth, R | 1 |
Ross, P | 1 |
Davis, J | 1 |
Kalandarov, SK | 1 |
Studnitsina, LA | 1 |
Tissot, R | 1 |
Gaillard, JM | 1 |
Guggisberg, M | 1 |
de Ajuriaguerra, J | 1 |
Boucher, R | 1 |
Nowaczynski, W | 1 |
Genest, J | 1 |
Yahr, MD | 1 |
Schear, MJ | 1 |
Barrett, RE | 1 |
Hoehn, MM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Drinking Water on the Pressor Response to Pseudoephedrine in Patients With Autonomic Failure[NCT02149901] | Early Phase 1 | 35 participants (Anticipated) | Interventional | 2014-10-31 | Terminated (stopped due to funding terminated) | ||
The Effect of Water Carbonation on Orthostatic Tolerance[NCT05621460] | 25 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 reviews available for dihydroxyphenylalanine and Blood Pressure, Low
Article | Year |
---|---|
Cardiovascular actions of DOPA mediated by the gene product of ocular albinism 1.
Topics: Animals; Baroreflex; Dihydroxyphenylalanine; Eye Proteins; Humans; Hypotension; Membrane Glycoprotei | 2014 |
On the function of central catecholamine neurons--their role in cardiovascular and arousal mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Bradycardia; Brain; Cardiovascular Physiological Phenomena; C | 1972 |
Therapeutic uses and side effects of L-dopa.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Barbiturates; Dihydroxyphenylalanine; Drug Synergism; | 1972 |
[Cardiovascular side effects of drugs].
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Contraceptives, Oral; Dihydroxyphenylalanine; Female; H | 1974 |
Levodopa in Parkinsonism.
Topics: Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Humans; Hypotension; Movem | 1971 |
9 trials available for dihydroxyphenylalanine and Blood Pressure, Low
Article | Year |
---|---|
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Combined treatment of parkinsonism with L-dopa and amantadine.
Topics: Aged; Amantadine; Chorea; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Hypotens | 1970 |
[Management of Parkinson's syndrome using levadopa. Results of a long-term study].
Topics: Administration, Oral; Adult; Aged; Antiparkinson Agents; Clinical Trials as Topic; Depression; Dihyd | 1972 |
Hypotension caused by L-dopa.
Topics: Central Nervous System; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Humans; Hypotens | 1970 |
L-dopa in Parkinsonism and the influence of previous thalamotomy.
Topics: Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Hypertension; Hypotension; M | 1971 |
Augmentation of sodium and potassium excretion, glomerular filtration rate and renal plasma flow by levodopa.
Topics: Administration, Oral; Aged; Aminohippuric Acids; Blood Pressure; Clinical Trials as Topic; Dihydroxy | 1971 |
L-Dopa treatment in Parkinson's Disease.
Topics: Age Factors; Anorexia Nervosa; Cardiovascular Diseases; Clinical Trials as Topic; Dihydroxyphenylala | 1970 |
Treatment of severe parkinsonism with L-dopa.
Topics: Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Hypotension; Male; Middle Aged; Pa | 1971 |
Action of L- -methyldopa-hydrazine on the blood pressure of patients receiving levodopa.
Topics: Adult; Aged; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydrazines; Hypotensi | 1972 |
51 other studies available for dihydroxyphenylalanine and Blood Pressure, Low
Article | Year |
---|---|
[Methyl-dopa and mebutamate. Hypotensive action of guanethidine. Comparative study].
Topics: Anti-Anxiety Agents; Antihypertensive Agents; Carbamates; Dihydroxyphenylalanine; Guanethidine; Hype | 1963 |
[The effect of intravenously administered DOPA on the blood pressure in pretreated alpha-methyl-DOPA hypertensives. Studies on the blood pressure-lowering mechanism of alpha-methyl-DOPA].
Topics: Antihypertensive Agents; Blood Pressure; Carboxy-Lyases; Dihydroxyphenylalanine; Hypertension; Hypot | 1962 |
[Evaluation of the hypotensive effect of aldomet (alpha-methyl DOPA) in the treatment of arterial hypertension, with reference to its effect on the metabolism of catecholamines].
Topics: Catecholamines; Dihydroxyphenylalanine; Hypertension; Hypotension; Methyldopa | 1962 |
[ACTION OF 5-HYDROXYTRYPTAMINE AND ITS ANTAGONISTS ON THE VASOMOTOR CENTERS].
Topics: Blood Pressure; Bradycardia; Cats; Dihydroxyphenylalanine; Hypotension; Hypothalamus; Lysergic Acid | 1964 |
Dopamine overload visualized in the basal ganglia of rabbit brain during heatstroke can be suppressed by hypothermia.
Topics: Animals; Basal Ganglia; Blood Pressure; Body Temperature; Cerebellum; Dihydroxyphenylalanine; Diseas | 2005 |
[Functional state of the cortical and medullary layers of the adrenals in primary arterial hypotension].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenal Medu | 1976 |
Spinal cord noradrenergic neurons are activated in hypotension.
Topics: Animals; Catecholamines; Dihydroxyphenylalanine; Hypotension; Male; Neurons; Norepinephrine; Rats; R | 1986 |
Use of levodopa with other drugs.
Topics: Adult; Aged; Antidepressive Agents; Antiemetics; Digoxin; Dihydroxyphenylalanine; Diuretics; Drug An | 1970 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphe | 1970 |
Treatment of Parkinson's disease with L-DOPA and an association L-DOPA plus a DOPA decarboxylase inhibitor.
Topics: Administration, Oral; Dihydroxyphenylalanine; Drug Synergism; Female; Gastrointestinal Diseases; Hum | 1972 |
[Cardiovascular effects of L-dopa and decarboxylase inhibitor on patients with Parkinson's disease].
Topics: Aged; Atrial Fibrillation; Bundle-Branch Block; Carboxy-Lyases; Cardiac Complexes, Premature; Cardio | 1973 |
Mydriatic responses to sympathomimetic amines in patients treated with L-dopa.
Topics: Adrenergic alpha-Antagonists; Dihydroxyphenylalanine; Humans; Hypotension; Mydriatics; Norepinephrin | 1969 |
Modification of the cardiovascular effects of L-dopa in anesthetized dogs by inhibitors of enzymes involved in catecholamine metabolism.
Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Carboxy-Lyases; Cresols; Dihydroxyphenylalanin | 1971 |
Parkinsonism and the hypotension caused by L-dopa.
Topics: Adrenergic alpha-Antagonists; Blood-Brain Barrier; Dihydroxyphenylalanine; Dilatation; Drug Synergis | 1971 |
[Indications and results of monoamine treatment in parkinsonian syndromes].
Topics: Aged; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; | 1972 |
Efficacy of and possible differences in tolerance to L-dopa tablets with different rates of release of the active substance.
Topics: Administration, Oral; Arrhythmias, Cardiac; Dihydroxyphenylalanine; Drug Tolerance; Feeding and Eati | 1974 |
[The state of the sympathetic-adrenal system in patients with primary arterial hypotension].
Topics: Adrenal Medulla; Adult; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Human | 1972 |
[Treatment of Parkinson syndromes with L-Dopa and the association of L-Dopa and a decarboxylase inhibitor].
Topics: Aged; Arrhythmias, Cardiac; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Synergism; Female; Gastroin | 1972 |
[The therapeutic effect of L-dopa].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Asthma; Brain; Dihydroxyphenylalanine; Dopamine; Human | 1972 |
Cardiovascular reactions to anaesthesia during treatment with levodopa.
Topics: Anesthesia, Dental; Anesthesia, General; Dihydroxyphenylalanine; Female; Halothane; Humans; Hyperten | 1973 |
[Comparison of the effect of L-Dopa and of an L-Dopa+decarboxylase inhibitor combination in Parkinson's disease].
Topics: Aged; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Drug Synergism; Female; Gastrointes | 1973 |
Levodopa and related drugs.
Topics: Amantadine; Apomorphine; Dihydroxyphenylalanine; Humans; Hydrazines; Hypotension; Mental Disorders; | 1973 |
Levodopa and induced-pain response. A study of patients with Parkinsonian and pain syndromes.
Topics: Aged; Cold Temperature; Dihydroxyphenylalanine; Electric Stimulation; Female; Hot Temperature; Human | 1973 |
[Therapy of Parkinson's syndrome].
Topics: Amantadine; Blood-Brain Barrier; Dihydroxyphenylalanine; Humans; Hypotension; Parkinson Disease | 1973 |
The treatment of parkinsonism with levodopa.
Topics: Aged; Anorexia Nervosa; Basal Ganglia Diseases; Depression; Dihydroxyphenylalanine; Extrapyramidal T | 1974 |
Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Arrhythmias, Cardiac; Benzyl Compounds; D | 1972 |
L-DOPA in Parkinson's disease. Results of a co-operative study in the Montreal area.
Topics: Administration, Oral; Aged; Basal Ganglia Diseases; Constipation; Dihydroxyphenylalanine; Evaluation | 1972 |
L-dopa and general anaesthesia.
Topics: Anesthesia, General; Dihydroxyphenylalanine; Female; Humans; Hypotension; Middle Aged; Parkinson Dis | 1971 |
L-dopa treatment of parkinsonism. Clinical observations on the use of amantadine hydrochloride.
Topics: Aged; Amantadine; Chlorides; Depression; Dihydroxyphenylalanine; Drug Hypersensitivity; Female; Foll | 1971 |
A year's experience of L-DOPA in the treatment of Parkinson's disease.
Topics: Adult; Age Factors; Aged; Dihydroxyphenylalanine; Female; Functional Laterality; Humans; Hypotension | 1971 |
Therapeutic guidelines and side effects encountered during L-dopa therapy in 100 cases of parkinsonism.
Topics: Carboxy-Lyases; Circadian Rhythm; Dihydroxyphenylalanine; Drug Resistance; Female; Gastrointestinal | 1971 |
Levodopa in treating Parkinsonism.
Topics: Adult; Aged; Athetosis; Dihydroxyphenylalanine; Female; Humans; Hypotension; Male; Middle Aged; Naus | 1971 |
[Adverse effects of interest].
Topics: Amenorrhea; Contraceptives, Oral; Dihydroxyphenylalanine; Female; Humans; Hypotension; Jaundice; Pos | 1971 |
Treatment of parkinsonism with levo-dopa: results in 302 cases.
Topics: Aged; Dihydroxyphenylalanine; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Hypotens | 1971 |
Coupling of hypotensive and anit-Parkinson effects with two dopaminergic drugs.
Topics: Apomorphine; Blood Pressure; Brain; Carbidopa; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Synergis | 1971 |
Effect of dopa on the catecholamine content of dog heart after hemorrhagic hypotension.
Topics: Animals; Dihydroxyphenylalanine; Dogs; Epinephrine; Heart; Hypotension; In Vitro Techniques; Myocard | 1965 |
Treatment of parkinsonism with L-dopa (study of 105 patients).
Topics: Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Anorexia Nervosa; Aspartate Aminotransfe | 1969 |
An evaluation of L-dopa in Parkinson patients.
Topics: Deglutition; Dihydroxyphenylalanine; Gait; Humans; Hypotension; Movement Disorders; Parkinson Diseas | 1969 |
Hypotension caused by L-dopa.
Topics: Dihydroxyphenylalanine; Female; Humans; Hypotension; Middle Aged; Parkinson Disease; Propranolol | 1970 |
Hypotension caused by L-dopa.
Topics: Animals; Blood Pressure; Cats; Dihydroxyphenylalanine; Dopamine; Guinea Pigs; Humans; Hypotension; R | 1970 |
Levodopa, Parkinson's disease, and hypotension.
Topics: Dihydroxyphenylalanine; Humans; Hypotension; Hypotension, Orthostatic; Parkinson Disease | 1970 |
Hypotension caused by L-dopa.
Topics: Dihydroxyphenylalanine; Humans; Hypotension; Propranolol | 1970 |
Plasma renin activity and levodopa in Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Female; Humans; Hypotension; Male; Middle Aged; Parkinson Disease; Pos | 1970 |
[Two years experience with L-DOPA in association with a decarboxylase inhibitor].
Topics: Acute Disease; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Humans; Hypoten | 1970 |
L-Dopa in the treatment of Parkinson's disease.
Topics: Activities of Daily Living; Aged; Dihydroxyphenylalanine; Hallucinations; Humans; Hypotension; Middl | 1970 |
The effect of L-dopa on chronotropic responses to cardioaccelerator nerve stimulation in dogs.
Topics: Acidosis; Animals; Arteries; Blood Pressure; Dihydroxyphenylalanine; Disease Models, Animal; Dogs; E | 1971 |
Preliminary observations on L-dopa in the treatment of Parkinson's disease.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aspartate Aminotransferases; Dihydroxyphenylalanine; | 1971 |
[Urinary excretion of catecholamines and their precursors in hypotensive patients].
Topics: Adult; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Humans; Hypotension; Male; Middle Aged | 1968 |
[Treatment of Parkinsonism with oral L-DOPA combined with a decarboxylase inhibitor (Ro IV 46.02)].
Topics: Adult; Aged; Anemia, Hemolytic; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Cell Count; Carb | 1969 |
Renin-aldosterone system in Parkinson's disease.
Topics: Aldosterone; Catecholamines; Dihydroxyphenylalanine; Female; Humans; Hypotension; Male; Middle Aged; | 1969 |
Treatment of parkinsonism with levodopa.
Topics: Adult; Aged; Anorexia Nervosa; Arrhythmias, Cardiac; Dihydroxyphenylalanine; Female; Gait; Humans; H | 1969 |