dihydroxyphenylalanine has been researched along with Bipolar Disorder in 32 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to investigate possible disturbances of the blood-brain transport mechanisms of monoamine precursors in manic-depressive illness and schizophrenia, we have measured the brain arterio-venous difference of DOPA, or 5-HTP, or tyrosine and tryptophan in 36 patients, during the infusion of either L-DOPA or L-5-HTP." | 7.66 | Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia. ( Gaillard, JM; Tissot, R, 1979) |
| "In order to investigate possible disturbances of the blood-brain transport mechanisms of monoamine precursors in manic-depressive illness and schizophrenia, we have measured the brain arterio-venous difference of DOPA, or 5-HTP, or tyrosine and tryptophan in 36 patients, during the infusion of either L-DOPA or L-5-HTP." | 3.66 | Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia. ( Gaillard, JM; Tissot, R, 1979) |
| "The probenecid technique was used in study of the central dopamine DA metabolism in patients with depressions, psychotic disorders, and Parkinson's disease." | 3.65 | Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders. ( Korf, J; Praag, HM; Schut, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (93.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jauhar, S | 1 |
| Nour, MM | 1 |
| Veronese, M | 1 |
| Rogdaki, M | 1 |
| Bonoldi, I | 1 |
| Azis, M | 1 |
| Turkheimer, F | 1 |
| McGuire, P | 1 |
| Young, AH | 1 |
| Howes, OD | 1 |
| Yatham, LN | 1 |
| Liddle, PF | 1 |
| Shiah, IS | 1 |
| Lam, RW | 1 |
| Ngan, E | 1 |
| Scarrow, G | 1 |
| Imperial, M | 1 |
| Stoessl, J | 1 |
| Sossi, V | 1 |
| Ruth, TJ | 1 |
| Gaillard, JM | 1 |
| Tissot, R | 2 |
| Mato, M | 1 |
| Uchiyama, Y | 1 |
| Kurihara, K | 1 |
| Karasawa, T | 1 |
| Praag, HM | 1 |
| Korf, J | 1 |
| Schut, T | 1 |
| Murphy, DL | 10 |
| Goodwin, FK | 12 |
| Bunney, WE | 8 |
| Paul, MI | 2 |
| Cramer, H | 2 |
| Post, RM | 1 |
| Brodie, HK | 4 |
| House, KM | 1 |
| Gordon, EK | 1 |
| Sachar, EJ | 1 |
| Frantz, AG | 1 |
| Altman, N | 1 |
| Sassin, J | 1 |
| Mandell, AJ | 1 |
| Spooner, CE | 1 |
| Matussek, N | 1 |
| Goldstein, M | 1 |
| Sack, RL | 1 |
| Henry, GM | 1 |
| Weingartner, H | 1 |
| Brown, WA | 1 |
| Bora, SS | 1 |
| Radichevich, I | 1 |
| Werner, SC | 1 |
| Rysánek, K | 1 |
| Gershon, ES | 1 |
| Takahashi, R | 1 |
| Pearlman, CA | 1 |
| Matlina, ESh | 1 |
| Osipova, MS | 1 |
| Ryback, RS | 1 |
| Schwab, RS | 1 |
| Muenter, MD | 1 |
| Tyce, GM | 1 |
8 reviews available for dihydroxyphenylalanine and Bipolar Disorder
| Article | Year |
|---|---|
The common pathophysiology of monaminergic psychoses: a new hypothesis.
Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrie | 1975 |
Psychochemical research studies in man.
Topics: Animals; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Depression; Dihydroxyphenylalanine; Hal | 1968 |
[Biochemistry of depression].
Topics: Animals; Bipolar Disorder; Brain; Central Nervous System; Depression; Dihydroxyphenylalanine; Glycol | 1972 |
Brain research and violent behavior. A summary and evaluation of the status of biomedical research on brain and aggressive violent behavior.
Topics: Aggression; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Bipolar Disorder; Bra | 1974 |
Central dopamine function in affective illness: evidence from precursors, enzyme inhibitors, and studies of central dopamine turnover.
Topics: Adult; Affective Symptoms; Anger; Bipolar Disorder; Central Nervous System; Depression; Diagnosis, D | 1974 |
L-dopa, behavioral activation and psychopathology.
Topics: Anger; Animals; Arousal; Behavior; Behavior, Animal; Bipolar Disorder; Brain; Catecholamines; Cerebr | 1972 |
[Relation of monoamines to mental disorders].
Topics: Amines; Animals; Bipolar Disorder; Catecholamines; Central Nervous System; Depression; Dihydroxyphen | 1970 |
L-DOPA, catecholamines, and behavior: a clinical and biochemical study in depressed patients.
Topics: Aged; Aggression; Anger; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Carboxy-Lyases; Catecho | 1970 |
7 trials available for dihydroxyphenylalanine and Bipolar Disorder
| Article | Year |
|---|---|
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; | 1974 |
Regular induction of hypomania by L-dopa in "bipolar" manic-depressive patients.
Topics: Antidepressive Agents; Bipolar Disorder; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylal | 1971 |
The "switch process" in manic-depressive illness. II. Relationship to catecholamines, REM sleep, and drugs.
Topics: Affective Symptoms; Antidepressive Agents; Bipolar Disorder; Catecholamines; Catechols; Dihydroxyphe | 1972 |
L-dopa, dopamine, and hypomania.
Topics: Adult; Bipolar Disorder; Brain; Brain Chemistry; Depression; Dihydroxyphenylalanine; Dopamine; Dose- | 1973 |
Artifactual elevation of PBI from an iodinated dye used to stain medicinal capsules pink.
Topics: Bipolar Disorder; Blood Proteins; Capsules; Carbonates; Chromatography, Paper; Clinical Trials as To | 1969 |
L-DOPA, catecholamines, and behavior: a clinical and biochemical study in depressed patients.
Topics: Aged; Aggression; Anger; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Carboxy-Lyases; Catecho | 1970 |
Studies of alpha-methyl-para-tyrosine, L-dopa, and L-tryptophan in depression and mania.
Topics: Bipolar Disorder; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Humans | 1971 |
18 other studies available for dihydroxyphenylalanine and Bipolar Disorder
| Article | Year |
|---|---|
A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Cross-Sectional Studies; Dihydroxyphenylalanine; Dopa | 2017 |
PET study of [(18)F]6-fluoro-L-dopa uptake in neuroleptic- and mood-stabilizer-naive first-episode nonpsychotic mania: effects of treatment with divalproex sodium.
Topics: Adult; Age Factors; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Corpus Striatum; Dihydr | 2002 |
Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia.
Topics: Adult; Bipolar Disorder; Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Humans; Middle Aged; Sc | 1979 |
Fluorescent substance in leukocytes and platelets of psychiatric patients.
Topics: Bipolar Disorder; Blood Platelets; Depression; Dihydroxyphenylalanine; Dopamine; Histocytochemistry; | 1977 |
Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders.
Topics: Adjustment Disorders; Bipolar Disorder; Brain; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; D | 1975 |
Clinical and pharmacological investigations of the psychobiology of the affective disorders.
Topics: Antidepressive Agents; Behavior; Bipolar Disorder; Catecholamines; Depression; Dihydroxyphenylalanin | 1971 |
Urinary cyclic A.M.P. in affective illness.
Topics: Adenine Nucleotides; Bipolar Disorder; Cyclic AMP; Dihydroxyphenylalanine; Humans; Lithium | 1970 |
Urinary cyclic AMP excretion in depression and mania. Effects of levodopa and lithium carbonate.
Topics: Acute Disease; Adenine Nucleotides; Adult; Affective Symptoms; Bipolar Disorder; Cyclic AMP; Depress | 1971 |
Growth hormone and prolactin in unipolar and bipolar depressed patients: responses to hypoglycemia and L-dopa.
Topics: Age Factors; Aged; Bipolar Disorder; Blood Glucose; Catecholamines; Depression; Dihydroxyphenylalani | 1973 |
Influence of affective states and psychoactive drugs on verbal learning and memory.
Topics: Bipolar Disorder; Carbonates; Depression; Dihydroxyphenylalanine; Humans; Imipramine; Lithium; Memor | 1973 |
Letter: Sex differences in growth hormone response.
Topics: Age Factors; Bipolar Disorder; Blood Glucose; Depression; Depression, Chemical; Dihydroxyphenylalani | 1974 |
The "switch process" in manic-depressive illness. 3. Theoretical implications.
Topics: Biological Transport, Active; Bipolar Disorder; Brain; Brain Chemistry; Calcium; Carbonates; Catecho | 1972 |
Psychobiological and pharmacological studies of manic-depressive illness.
Topics: Adult; Aged; Bipolar Disorder; Catechols; Depression; Dihydroxyphenylalanine; Dopamine; Female; Glyc | 1972 |
[Amine precursors and manic-depressive illness].
Topics: Amines; Bipolar Disorder; Catecholamines; Circadian Rhythm; Dihydroxyphenylalanine; Humans; Tyrosine | 1971 |
Manic behavior and levodopa.
Topics: Bipolar Disorder; Dihydroxyphenylalanine; Humans; Lithium; Male; Middle Aged; Parkinson Disease | 1971 |
[The effect of aminazine on the excretion of adrenaline noradrenaline, dopamine and dopa in healthy subjects and in the manic phase of manic-depressive psychosis].
Topics: Bipolar Disorder; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Norepinephr | 1970 |
Manic response to levodopa therapy. Report of a case.
Topics: Aged; Bipolar Disorder; Dihydroxyphenylalanine; Humans; Lithium; Male; Parkinson Disease; Psychoses, | 1971 |
L-dopa therapy of Parkinson's disease: plasma L-dopa concentration, therapeutic response, and side effects.
Topics: Bipolar Disorder; Body Weight; Dihydroxyphenylalanine; Fasting; Humans; Muscular Diseases; Neurologi | 1971 |