dihydroxyphenylalanine has been researched along with Atrophy in 8 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Striatal 18F-Dopa uptake and brain glucose metabolism were studied by PET with 6-L-[18F]flurodopa and [18F]fluorodeoxyglucose in 11 patients with syndrome of progressive ataxia." | 5.07 | Striatal 18F-dopa uptake and brain glucose metabolism by PET in patients with syndrome of progressive ataxia. ( Akashi, Y; Fukumura, T; Goto, I; Hosokawa, S; Ichiya, Y; Kato, M; Kuwabara, Y; Masuda, K; Otsuka, M; Yoshida, T, 1994) |
| "We estimated regional and global metabolic rates for glucose using 18F-fluorodeoxyglucose (FDG) and PET in six patients with hemiparkinsonism-hemiatrophy syndrome (HPHA; mean age, 41." | 3.69 | Metabolic topography of the hemiparkinsonism-hemiatrophy syndrome. ( Chaly, T; Dhawan, V; Eidelberg, D; Fahn, S; Giladi, N; Ishikawa, T; Przedborski, S; Spetsieris, P; Takikawa, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| da Silva Schmitt, G | 1 |
| Martinez, ARM | 1 |
| da Graça, FF | 1 |
| de Lima, FD | 1 |
| Bonadia, LC | 1 |
| Amorim, BJ | 1 |
| Nucci, A | 1 |
| França, MC | 1 |
| Hilker, R | 1 |
| Thomas, AV | 1 |
| Klein, JC | 1 |
| Weisenbach, S | 1 |
| Kalbe, E | 1 |
| Burghaus, L | 1 |
| Jacobs, AH | 1 |
| Herholz, K | 1 |
| Heiss, WD | 1 |
| Jokinen, P | 1 |
| Brück, A | 1 |
| Aalto, S | 1 |
| Forsback, S | 1 |
| Parkkola, R | 1 |
| Rinne, JO | 1 |
| Gosset, A | 1 |
| Pellissier, JF | 1 |
| Delpuech, F | 1 |
| Khalil, R | 1 |
| Przedborski, S | 1 |
| Giladi, N | 1 |
| Takikawa, S | 1 |
| Ishikawa, T | 1 |
| Dhawan, V | 1 |
| Spetsieris, P | 1 |
| Chaly, T | 1 |
| Fahn, S | 1 |
| Eidelberg, D | 1 |
| Otsuka, M | 1 |
| Ichiya, Y | 1 |
| Kuwabara, Y | 1 |
| Hosokawa, S | 1 |
| Akashi, Y | 1 |
| Yoshida, T | 1 |
| Fukumura, T | 1 |
| Masuda, K | 1 |
| Goto, I | 1 |
| Kato, M | 1 |
| Nagasawa, H | 1 |
| Tanji, H | 1 |
| Nomura, H | 1 |
| Saito, H | 1 |
| Itoyama, Y | 1 |
| Kimura, I | 1 |
| Tuji, S | 1 |
| Fujiwara, T | 1 |
| Iwata, R | 1 |
| Itoh, M | 1 |
| Ido, T | 1 |
| Brooks, DJ | 1 |
| Salmon, EP | 1 |
| Mathias, CJ | 1 |
| Quinn, N | 1 |
| Leenders, KL | 1 |
| Bannister, R | 1 |
| Marsden, CD | 1 |
| Frackowiak, RS | 1 |
2 trials available for dihydroxyphenylalanine and Atrophy
| Article | Year |
|---|---|
Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways.
Topics: Acetates; Acetylcholine; Acetylcholinesterase; Aged; Atrophy; Binding, Competitive; Brain; Brain Map | 2005 |
Striatal 18F-dopa uptake and brain glucose metabolism by PET in patients with syndrome of progressive ataxia.
Topics: Adult; Aged; Ataxia; Atrophy; Brain Chemistry; Brain Stem; Cerebellum; Deoxyglucose; Dihydroxyphenyl | 1994 |
6 other studies available for dihydroxyphenylalanine and Atrophy
| Article | Year |
|---|---|
Dopa-Responsive Parkinsonism in a Patient With Homozygous RFC1 Expansions.
Topics: Atrophy; Dihydroxyphenylalanine; Homozygote; Humans; Multiple System Atrophy; Parkinsonian Disorders | 2020 |
Impaired cognitive performance in Parkinson's disease is related to caudate dopaminergic hypofunction and hippocampal atrophy.
Topics: Aged; Analysis of Variance; Atrophy; Caudate Nucleus; Cognition Disorders; Dihydroxyphenylalanine; D | 2009 |
[Striatonigral degeneration associated with olivopontocerebellar atrophy. Anatomo-clinical study of 3 cases. Nosologic discussion].
Topics: Adult; Atrophy; Brain Diseases; Cerebellar Diseases; Corpus Striatum; Dihydroxyphenylalanine; Female | 1983 |
Metabolic topography of the hemiparkinsonism-hemiatrophy syndrome.
Topics: Adult; Atrophy; Brain; Deoxyglucose; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Glucose | 1994 |
PET study of cerebral glucose metabolism and fluorodopa uptake in patients with corticobasal degeneration.
Topics: Aged; Apraxias; Atrophy; Basal Ganglia; Basal Ganglia Diseases; Brain Diseases; Cerebral Cortex; Cer | 1996 |
The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET.
Topics: Adult; Aged; Atrophy; Autonomic Nervous System; Autonomic Nervous System Diseases; Brain Diseases; C | 1990 |