dihydroxyphenylalanine has been researched along with Atherosclerotic Parkinsonism in 82 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Transient exposure to the toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) produces a syndrome resembling idiopathic parkinsonism (IP)." | 3.69 | Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions. ( Calne, DB; Langston, JW; Schulzer, M; Snow, BJ; Tetrud, JW; Vingerhoets, FJ, 1994) |
| "Susceptibility to Parkinson's disease (PD) is believed to involve an interaction between genetic and environmental factors." | 1.51 | The role of exposure to pesticides in the etiology of Parkinson's disease: a ( Djaldetti, R; Greenbaum, L; Lorberboym, M; Poewe, W; Rigbi, A; Roditi, Y; Scherfler, C; Steinmetz, A, 2019) |
| " We retrospectively analyzed data from 17 stable HP rhesus monkeys treated long-term with chronic intermittent dosing of levodopa (LD) in an attempt to induce choreoathetoid and dystonic dyskinesias." | 1.37 | Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys. ( Bakay, RA; Deogaonkar, M; Lieu, CA; Subramanian, T, 2011) |
| "Parkinsonism without dystonia has been reported in several older members of families with DRD." | 1.29 | Clinical heterogeneity of dopa-responsive dystonia: PET observations. ( Calne, DB; Nygaard, TG; Snow, BJ; Takahashi, H, 1993) |
| "Two patients with Parkinson's disease who underwent implantation of fetal mesencephalic tissue into the putamen were serially studied using positron emission tomography and [18F]6-L-fluorodopa ([18F]dopa)." | 1.28 | Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants. ( Björklund, A; Bloomfield, PM; Brooks, DJ; Brundin, P; Leenders, KL; Lindvall, O; Marsden, CD; Rehncrona, S; Sawle, GV; Widner, H, 1992) |
| "To investigate the relation between "on-off" fluctuations in symptomatology and bioavailability of dopa in patients with Parkinson's disease, five Parkinsonian patients with pronounced "on-off" symptoms were studied." | 1.27 | "On-off" phenomenon in Parkinson's disease: correlation to the concentration of dopa in plasma. ( Carlsson, A; Eriksson, T; Granérus, AK; Linde, A; Magnusson, T, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (60.98) | 18.7374 |
| 1990's | 25 (30.49) | 18.2507 |
| 2000's | 2 (2.44) | 29.6817 |
| 2010's | 5 (6.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Djaldetti, R | 1 |
| Steinmetz, A | 1 |
| Rigbi, A | 1 |
| Scherfler, C | 1 |
| Poewe, W | 2 |
| Roditi, Y | 1 |
| Greenbaum, L | 1 |
| Lorberboym, M | 1 |
| Kanazawa, M | 1 |
| Ohba, H | 1 |
| Harada, N | 1 |
| Kakiuchi, T | 1 |
| Muramatsu, S | 1 |
| Tsukada, H | 1 |
| Becker, G | 1 |
| Bahri, MA | 1 |
| Michel, A | 1 |
| Hustadt, F | 1 |
| Garraux, G | 1 |
| Luxen, A | 1 |
| Lemaire, C | 1 |
| Plenevaux, A | 1 |
| Lieu, CA | 1 |
| Deogaonkar, M | 1 |
| Bakay, RA | 1 |
| Subramanian, T | 1 |
| Kita, H | 1 |
| Kita, T | 1 |
| Eriksson, T | 1 |
| Magnusson, T | 1 |
| Carlsson, A | 3 |
| Linde, A | 1 |
| Granérus, AK | 1 |
| Lang, AE | 1 |
| Tranchant, C | 1 |
| Ruh, D | 1 |
| Warter, JM | 1 |
| Cordes, M | 1 |
| Richard, MG | 1 |
| Bennett, JP | 1 |
| Vingerhoets, FJ | 1 |
| Snow, BJ | 3 |
| Tetrud, JW | 1 |
| Langston, JW | 2 |
| Schulzer, M | 1 |
| Calne, DB | 4 |
| Miletich, RS | 1 |
| Comi, G | 1 |
| Bankiewicz, K | 1 |
| Plunkett, R | 1 |
| Adams, R | 1 |
| Di Chiro, G | 1 |
| Kopin, IJ | 2 |
| Takahashi, H | 1 |
| Nygaard, TG | 1 |
| Okada, A | 1 |
| Nakamura, K | 1 |
| Bhatt, MH | 1 |
| Nomoto, M | 1 |
| Osame, M | 1 |
| Burn, DJ | 1 |
| Brooks, DJ | 4 |
| Miyagi, Y | 1 |
| Morioka, T | 1 |
| Otsuka, M | 2 |
| Fukui, M | 1 |
| Hume, SP | 1 |
| Lammertsma, AA | 1 |
| Myers, R | 1 |
| Rajeswaran, S | 1 |
| Bloomfield, PM | 2 |
| Ashworth, S | 1 |
| Fricker, RA | 1 |
| Torres, EM | 1 |
| Watson, I | 1 |
| Jones, T | 1 |
| Katayama, Y | 1 |
| Schneider, JS | 2 |
| Leff, SE | 1 |
| Rendahl, KG | 1 |
| Spratt, SK | 1 |
| Kang, UJ | 1 |
| Mandel, RJ | 1 |
| Doudet, DJ | 2 |
| Chan, GL | 1 |
| Holden, JE | 1 |
| McGeer, EG | 1 |
| Aigner, TA | 1 |
| Wyatt, RJ | 1 |
| Ruth, TJ | 2 |
| Rudnicki, SA | 1 |
| Harik, SI | 1 |
| Dhodapkar, M | 1 |
| Barlogie, B | 1 |
| Eidelberg, D | 1 |
| Fernández-Ruiz, J | 1 |
| Doudet, D | 1 |
| Aigner, TG | 2 |
| Poyot, T | 1 |
| Condé, F | 1 |
| Grégoire, MC | 1 |
| Frouin, V | 1 |
| Coulon, C | 1 |
| Fuseau, C | 1 |
| Hinnen, F | 1 |
| Dollé, F | 1 |
| Hantraye, P | 1 |
| Bottlaender, M | 1 |
| Thobois, S | 1 |
| Guillouet, S | 1 |
| Broussolle, E | 1 |
| Loos, D | 1 |
| Halbhübner, K | 1 |
| Kehr, W | 1 |
| Herken, H | 1 |
| Kandel', EI | 1 |
| Iadgarov, IS | 1 |
| Janzik, HH | 1 |
| Ryzhkova, MN | 1 |
| Tarasova, LA | 1 |
| McLellan, CA | 1 |
| Cohen, RM | 1 |
| Mierau, J | 1 |
| Schingnitz, G | 1 |
| Widner, H | 2 |
| Tetrud, J | 1 |
| Rehncrona, S | 2 |
| Snow, B | 1 |
| Brundin, P | 2 |
| Gustavii, B | 1 |
| Björklund, A | 2 |
| Lindvall, O | 2 |
| Sawle, GV | 1 |
| Leenders, KL | 1 |
| Marsden, CD | 1 |
| Ichiya, Y | 1 |
| Hosokawa, S | 1 |
| Kuwabara, Y | 1 |
| Tahara, T | 1 |
| Fukumura, T | 1 |
| Kato, M | 1 |
| Masuda, K | 1 |
| Goto, I | 1 |
| Barrio, JR | 1 |
| Huang, SC | 1 |
| Melega, WP | 1 |
| Yu, DC | 1 |
| Hoffman, JM | 1 |
| Satyamurthy, N | 1 |
| Mazziotta, JC | 1 |
| Phelps, ME | 1 |
| Rosenberg, NL | 1 |
| Myers, JA | 1 |
| Martin, WR | 1 |
| Wolters, EC | 1 |
| Huang, CC | 1 |
| Clark, C | 1 |
| Peppard, RF | 1 |
| Okada, J | 1 |
| Chu, NS | 1 |
| Adam, MJ | 1 |
| Li, D | 1 |
| Chiueh, CC | 1 |
| Firnau, G | 1 |
| Burns, RS | 1 |
| Nahmias, C | 1 |
| Chirakal, R | 1 |
| Garnett, ES | 1 |
| Dumont, M | 1 |
| Lamarre, Y | 1 |
| Klawans, HL | 3 |
| Goetz, C | 1 |
| Westheimer, R | 1 |
| Steg, G | 1 |
| Vogt, M | 1 |
| Martin, WE | 1 |
| Resch, JA | 1 |
| Baker, AB | 1 |
| Shimomura, SK | 1 |
| Hornykiewicz, O | 1 |
| Atadzhanov, M | 1 |
| Glabb, J | 1 |
| Hübner, W | 1 |
| Glabb, S | 1 |
| Metzel, E | 1 |
| Brion, S | 1 |
| Guérin, R | 1 |
| Albert, E | 2 |
| Cernacek, J | 1 |
| Brezny, I | 1 |
| Jagr, J | 1 |
| Fischer, PA | 2 |
| Horst, WD | 1 |
| Pool, WR | 1 |
| Spiegel, HE | 1 |
| Strelkova, NI | 1 |
| Zeĭnalov, RK | 1 |
| Tret'iakova, KA | 2 |
| Samoĭlova, ZT | 3 |
| Cincă, I | 1 |
| Bulandra, R | 1 |
| Serbănesco, A | 1 |
| Ninosu, N | 1 |
| Schneider, E | 1 |
| Jacobi, P | 1 |
| Maxion, H | 1 |
| Presthus, J | 1 |
| Stoliarova, LG | 1 |
| Kistenev, BA | 1 |
| Ballivet, J | 1 |
| Marin, A | 1 |
| Gisselmann, A | 1 |
| Khaliutina, LV | 1 |
| Lieberman, AN | 1 |
| Gauthier, G | 1 |
| Juge, O | 1 |
| Birchler, A | 1 |
| Shavolina, VA | 1 |
| Degkwitz, R | 2 |
| Ringel, SP | 1 |
| Guggenheim, MA | 1 |
| Couch, JR | 1 |
| Weinberg, W | 1 |
| Kimura, N | 1 |
| Tsukue, I | 1 |
| Cotzias, GC | 1 |
| Bruno, A | 1 |
| Bruno, SC | 1 |
| Hornykiewicz, OD | 1 |
| Hippius, H | 1 |
| Logemann, G | 1 |
| Gjerris, F | 1 |
| Oehme, P | 1 |
| Schwarz, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PET Whole Body Biodistribution and Test Retest Brain Imaging Studies Using a Dopamine Transporter Ligand [18F]FECNT[NCT00083629] | Phase 1 | 30 participants | Interventional | 2004-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for dihydroxyphenylalanine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Hemiatrophy, juvenile-onset exertional alternating leg paresis, hypotonia, and hemidystonia and adult-onset hemiparkinsonism: the spectrum of hemiparkinsonism-hemiatrophy syndrome.
Topics: Antiparkinson Agents; Blood Glucose; Carbidopa; Contrast Media; Deoxyglucose; Dihydroxyphenylalanine | 1995 |
[Type II Charcot-Marie-Tooth and dopa-sensitive Parkinson disease].
Topics: Charcot-Marie-Tooth Disease; Dihydroxyphenylalanine; Humans; Male; Middle Aged; Parkinson Disease, S | 1994 |
[Functional neurosurgery with an implantable and programmable pulse-generator: control of involuntary movement disorders].
Topics: Brain; Dihydroxyphenylalanine; Electric Stimulation; Electrodes, Implanted; Humans; Movement Disorde | 1997 |
Contributions of PET and SPECT to the understanding of the pathophysiology of Parkinson's disease.
Topics: Aging; Animals; Antiparkinson Agents; Basal Ganglia; Brain Tissue Transplantation; Cell Transplantat | 2001 |
Pathophysiology of schizophrenia and the striatum.
Topics: Adult; Amphetamine; Animals; Basal Ganglia; Catalepsy; Caudate Nucleus; Dihydroxyphenylalanine; Dopa | 1972 |
Pathological aspects on Parkinson's syndrome.
Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Central Nervous System; Chlorpromazine; Corpus Stria | 1972 |
Drug-induced changes in brain dopamine and their relation to parkinsonism.
Topics: Animals; Basal Ganglia; Brain; Cerebral Ventricles; Dihydroxyphenylalanine; Dopamine; Electric Stimu | 1970 |
Biochemical and pharmacological aspects of Parkinsonism.
Topics: Animals; Blood-Brain Barrier; Brain; Central Nervous System; Chemoreceptor Cells; Chlorpromazine; Co | 1972 |
The pharmacology of parkinsonism (a review).
Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa | 1968 |
Dopamine and extrapyramidal motor function and dysfunction.
Topics: Animals; Apomorphine; Basal Ganglia Diseases; Butyrophenones; Caudate Nucleus; Dihydroxyphenylalanin | 1972 |
[Hereditary aspects of Parkinson's disease (review of the literature)].
Topics: Adolescent; Adult; Aged; Catecholamines; Child; Dihydroxyphenylalanine; Diseases in Twins; Female; G | 1973 |
[Treatment of Parkinson's syndrome using L-dopa. 2].
Topics: Adult; Aged; Arrhythmias, Cardiac; Dihydroxyphenylalanine; Electrocardiography; Electromyography; Ha | 1973 |
Parkinson's syndrome--modern therapy, known facts and unanswered questions.
Topics: Brain; Brain Stem; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Dopamine; Extrapyramidal T | 1973 |
[Therapy of Parkinsonian syndrome using L-dopa. Current state and problems].
Topics: Administration, Oral; Basal Ganglia Diseases; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Dr | 1974 |
[l-dopa treatment of Parkinson's syndrome and mechanism of action of neuroleptics].
Topics: Acetylcholine; Basal Ganglia; Butyrophenones; Chorea; Dihydroxyphenylalanine; Dopamine; Extrapyramid | 1969 |
[Therapy and problems of parkinsonism].
Topics: Adult; Aged; Amantadine; Animals; Antidepressive Agents; Apomorphine; Brain Chemistry; Brain Stem; D | 1971 |
4 trials available for dihydroxyphenylalanine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Caudate Nucleus; Corpus Striatum; Dihydroxyphen | 1992 |
[Combination of L-dopa and sulpiride in the treatment of Parkinson's disease].
Topics: Aged; Antiparkinson Agents; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Interactions; Dru | 1973 |
Stabilographic evaluation of dopaminergic and anticholinergic treatment of parkinsonism.
Topics: Adult; Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Synergism; Humans; Middle Aged; | 1973 |
Effects of L-DOPA on pharmacological parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Haloper | 1966 |
62 other studies available for dihydroxyphenylalanine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
The role of exposure to pesticides in the etiology of Parkinson's disease: a
Topics: Aged; Austria; Cohort Studies; Dihydroxyphenylalanine; Environmental Exposure; Female; Humans; Israe | 2019 |
Evaluation of 6-11C-Methyl-m-Tyrosine as a PET Probe for Presynaptic Dopaminergic Activity: A Comparison PET Study with β-11C-l-DOPA and 18F-FDOPA in Parkinson Disease Monkeys.
Topics: Animals; Brain; Carbidopa; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Dopa | 2016 |
Comparative assessment of 6-[
Topics: Animals; Apomorphine; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Disease Models, | 2017 |
Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Carot | 2011 |
Cortical stimulation evokes abnormal responses in the dopamine-depleted rat basal ganglia.
Topics: Action Potentials; Animals; Basal Ganglia; Cerebral Cortex; Dihydroxyphenylalanine; Male; Motor Acti | 2011 |
"On-off" phenomenon in Parkinson's disease: correlation to the concentration of dopa in plasma.
Topics: Aged; Amino Acids; Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Female; Humans; Levodopa; Mal | 1984 |
[Presynaptic nigrostriatal function in Parkinson disease and Parkinson-plus syndromes. Comparative studies using positron emission tomography with L-6-(18F)fluorodopa].
Topics: Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihydroxyphenylalanine; Dominance, Cerebral; Dopami | 1994 |
Regulation by D2 dopamine receptors of in vivo dopamine synthesis in striata of rats and mice with experimental parkinsonism.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Dihydroxyphenylalanine; Dopa | 1994 |
Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihyd | 1994 |
6-[18F]fluoro-L-dihydroxyphenylalanine metabolism and positron emission tomography after catechol-O-methyltransferase inhibition in normal and hemiparkinsonian monkeys.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catechols; Dihydroxyphenylalanine; Fluorine Radioi | 1993 |
Clinical heterogeneity of dopa-responsive dystonia: PET observations.
Topics: Adult; Aged; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dystonia; Female; Hum | 1993 |
PET scan study on the dopaminergic system in a Japanese patient with hereditary progressive dystonia (Segawa's disease). Case report.
Topics: Corpus Striatum; Dihydroxyphenylalanine; Dystonia; Female; Humans; Japan; Levodopa; Middle Aged; Neu | 1993 |
Nigral dysfunction in drug-induced parkinsonism: an 18F-dopa PET study.
Topics: Adult; Aged; Animals; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Femal | 1993 |
Striatal glucose metabolism and [18F]fluorodopa uptake in a patient with tumor-induced hemiparkinsonism.
Topics: Blood Glucose; Corpus Striatum; Dihydroxyphenylalanine; Dominance, Cerebral; Dopamine; Electromyogra | 1993 |
The potential of high-resolution positron emission tomography to monitor striatal dopaminergic function in rat models of disease.
Topics: Animals; Carbidopa; Carbon Isotopes; Carrier Proteins; Cerebellum; Dihydroxyphenylalanine; Disease M | 1996 |
Preservation of autoreceptor-mediated increases in dopamine synthesis in aged mice with experimentally-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromat | 1997 |
In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase.
Topics: 3T3 Cells; Animals; Antioxidants; Antiparkinson Agents; Apomorphine; Behavior, Animal; Biopterins; C | 1998 |
6-[18F]Fluoro-L-DOPA PET studies of the turnover of dopamine in MPTP-induced parkinsonism in monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Corpus | 1998 |
Nervous system dysfunction in Waldenström's macroglobulinemia: response to treatment.
Topics: Antibodies, Monoclonal; Bone Marrow Transplantation; Dihydroxyphenylalanine; Fluorine Radioisotopes; | 1998 |
Spatial memory improvement by levodopa in parkinsonian MPTP-treated monkeys.
Topics: Animals; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine Agents; Fluorine Radioisotopes; Levo | 1999 |
Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates: comparison with 6-[18F]fluoro-L-dopa.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; | 2001 |
Action of dopamine agonists on parkinson-like muscle rigidity induced by 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Animals; Brain Chemistry; Corpus Striatum; Diencephalon; Dihydroxyphenylalanine | 1979 |
[Catecholamine excretion and treatment of parkinsonism with midantan].
Topics: Adult; Aged; Amantadine; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Huma | 1976 |
[Drug-induced extrapyramidal symptoms].
Topics: Anticonvulsants; Antidepressive Agents; Antihypertensive Agents; Basal Ganglia Diseases; Contracepti | 1975 |
[Pathogenesis and treatment of manganese induced Parkinsonism].
Topics: Adult; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Manganese Poisoning; Norepinephrine; | 1975 |
Positron emission tomography with 18F-dopa: interpretation and biological correlates in nonhuman primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbidopa; Cerebral Cortex; Corpus Striatum; | 1992 |
Biochemical and pharmacological studies on pramipexole, a potent and selective dopamine D2 receptor agonist.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzothiazoles; Corpus Striatum; Dihydroxyphenylalanine; Do | 1992 |
Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Brain Tissue Transplantation; Caudate Nucleus; Dihydro | 1992 |
Striatal blood flow, glucose metabolism and 18F-dopa uptake: difference in Parkinson's disease and atypical parkinsonism.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain Mapping; Corpus Striatum; Diagnosis, Differential; Dih | 1991 |
Detection of preclinical Parkinson's disease with PET.
Topics: Adult; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Diseases in Twins; Dopamine; Female | 1991 |
Detection of preclinical Parkinson's disease with PET.
Topics: Adult; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Diseases in Twins; Dopamine; Female | 1991 |
6-[18F]fluoro-L-dopa probes dopamine turnover rates in central dopaminergic structures.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanin | 1990 |
Cyanide-induced parkinsonism: clinical, MRI, and 6-fluorodopa PET studies.
Topics: Cyanides; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson D | 1989 |
Positron emission tomography in manganese intoxication.
Topics: Adult; Brain; Chronic Disease; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Manganese | 1989 |
Determination and visualization of damage to striatal dopaminergic terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by [18F]-labeled 6-fluoro-L-dopa and positron emission tomography.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Maca | 1987 |
Experimental tremor following CNS lesions in monkeys.
Topics: Animals; Cerebellar Nuclei; Dihydroxyphenylalanine; Disease Models, Animal; Haplorhini; Mesencephalo | 1973 |
Basic concepts underlying recent developments in the field of Parkinson's disease.
Topics: Biogenic Amines; Brain; Dihydroxyphenylalanine; Disease Models, Animal; Humans; Parkinson Disease; P | 1971 |
Juvenile parkinsonism.
Topics: Adult; Age Factors; Aged; Diagnosis, Differential; Dihydroxyphenylalanine; Dopamine; Humans; Male; M | 1971 |
Parkinsonism.
Topics: Amantadine; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Parasympatholytics; Parkinson | 1972 |
[Surgical management of parkinsonism].
Topics: Age Factors; Basal Ganglia; Brain; Caudate Nucleus; Cerebellar Nuclei; Corpus Striatum; Dihydroxyphe | 1974 |
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain; | 1973 |
[Correlation of biochemical findings and the state of the neuromuscular apparatus in patients with parkinsonism during use of decimeter wave therapy].
Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Electromagnetic Phenomena; Electromyography; Epinephr | 1973 |
[The reserpine model of parkinsonism and changes in the metabolism of mediators].
Topics: Animals; Brain; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Epinephrine; Male; Norepin | 1973 |
[Current medical treatment of Parkinsonian syndromes].
Topics: Adult; Age Factors; Aged; Amantadine; Antiparkinson Agents; Dihydroxyphenylalanine; Drug Combination | 1973 |
[Combination therapy of Parkinson's syndrome using L-dopa and a decarboxylase inhibitor].
Topics: Aged; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Female; Humans; Hyperkinesis; Male; | 1973 |
[The Parkinson syndrome].
Topics: Acetylcholine; Amino Acids; Dihydroxyphenylalanine; Dopamine; Humans; Parkinson Disease, Secondary | 1973 |
[Treatment of parkinsonism with the drug L-DOPA].
Topics: Brain Diseases; Dihydroxyphenylalanine; Hepatolenticular Degeneration; Humans; Movement Disorders; P | 1973 |
[Aspects of hypersexuality observed in parkinsonian patients treated by L-dopa].
Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Gonadal Steroid Hormones; Humans; Hypothalamo-Hypophyse | 1973 |
[Effect of l-dopa on the development of reserpine parkinsonism and the metabolism of catecholamines in rats].
Topics: Animals; Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Drug Interactions; Male; Parkinson | 1973 |
Parkinson's disease: a clinical review.
Topics: Adult; Aged; Brain Diseases; Bulbar Palsy, Progressive; Dementia; Diagnosis, Differential; Dihydroxy | 1974 |
Parkinsonian syndromes. Treatment by association of L-dopa plus decarboxylase inhibitor.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Decarboxylation; Depression; Depressio | 1974 |
[Changes of catecholamine metabolism and symptoms of parkinsonism in rats with manganotoxicosis].
Topics: Animals; Brain; Catecholamines; Chlorides; Dihydroxyphenylalanine; Dopamine; Epinephrine; Male; Mang | 1974 |
[Drug-induced Parkinson's syndrome].
Topics: Acetylcholinesterase; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disor | 1972 |
Carbon monoxide-induced Parkinsonism.
Topics: Carbon Monoxide Poisoning; Dihydroxyphenylalanine; Electroencephalography; Humans; Male; Middle Aged | 1972 |
Motor dysfunction as a permanent complication of methanol ingestion. Presentation of a case with a beneficial response to levodopa treatment.
Topics: Adolescent; Dihydroxyphenylalanine; Female; Humans; Methanol; Motor Cortex; Movement Disorders; Opti | 1971 |
L-DOPA therapy in drug-induced parkinsonism evaluated by the method measuring the facial expression.
Topics: Adult; Dihydroxyphenylalanine; Facial Expression; Female; Humans; Male; Movement; Parkinson Disease; | 1971 |
Levodopa in the treatment of Parkinsonism.
Topics: Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenylalanine; D | 1971 |
Physiologic, biochemical, and pathological backgrounds of levodopa and possibilities for the future.
Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Humans; Injections, Intraperitoneal; Injections, I | 1970 |
[Effect of dioxyphenylalanine (L-DOPA) on extrapyramidal motoric hyperkineses after prolonged neuroleptic therapy].
Topics: Depression, Chemical; Dihydroxyphenylalanine; Drive; Emotions; Extrapyramidal Tracts; Female; Humans | 1970 |
Transitory procaine-induced Parkinsonism.
Topics: Chronic Disease; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Parkinson Disease; Parkinson D | 1971 |
Differentiation of tardive dyskinesias and drug-induced Parkinsonism.
Topics: Amantadine; Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Hyperkinesis; Movement Disorder | 1971 |
[Etiology and therapy of Parkinson's syndrome and related pharmacological concepts shown in experimental models].
Topics: Animals; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Humans; Hypothermia; Mic | 1966 |