dihydroxyphenylalanine has been researched along with Astrocytoma in 7 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nineteen patients with newly diagnosed high-grade gliomas underwent computed tomography (CT), gadolinium contrast-enhanced MRI, and (18)F-FDOPA PET/CT." | 3.79 | High-grade glioma radiation therapy target volumes and patterns of failure obtained from magnetic resonance imaging and 18F-FDOPA positron emission tomography delineations from multiple observers. ( Benard, F; Chan, EK; Cheung, A; Hsu, F; Kosztyla, R; Ma, R; Moiseenko, V; Nichol, A; Wilson, D; Zhang, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Morana, G | 2 |
| Bottoni, G | 1 |
| Mancardi, MM | 1 |
| Verrico, A | 1 |
| Piccardo, A | 2 |
| Decazes, P | 1 |
| Hapdey, S | 1 |
| Humbert, O | 1 |
| Marie-Cardine, A | 1 |
| Vera, P | 1 |
| Kosztyla, R | 1 |
| Chan, EK | 1 |
| Hsu, F | 1 |
| Wilson, D | 1 |
| Ma, R | 1 |
| Cheung, A | 1 |
| Zhang, S | 1 |
| Moiseenko, V | 1 |
| Benard, F | 1 |
| Nichol, A | 1 |
| Kratochwil, C | 1 |
| Combs, SE | 1 |
| Leotta, K | 1 |
| Afshar-Oromieh, A | 1 |
| Rieken, S | 1 |
| Debus, J | 1 |
| Haberkorn, U | 1 |
| Giesel, FL | 1 |
| Milanaccio, C | 1 |
| Puntoni, M | 1 |
| Nozza, P | 1 |
| Cama, A | 1 |
| Zefiro, D | 1 |
| Cabria, M | 1 |
| Rossi, A | 1 |
| Garrè, ML | 1 |
| Walter, F | 1 |
| Cloughesy, T | 1 |
| Walter, MA | 1 |
| Lai, A | 1 |
| Nghiemphu, P | 1 |
| Wagle, N | 1 |
| Fueger, B | 1 |
| Satyamurthy, N | 1 |
| Phelps, ME | 1 |
| Czernin, J | 1 |
| De Bault, LE | 1 |
| Millard, SA | 1 |
7 other studies available for dihydroxyphenylalanine and Astrocytoma
| Article | Year |
|---|---|
Seizure-Induced Increased 18F-DOPA Uptake in a Child With Diffuse Astrocytoma and Transient Brain MRI Abnormalities Related to Status Epilepticus.
Topics: Astrocytoma; Brain; Brain Neoplasms; Child, Preschool; Dihydroxyphenylalanine; Humans; Magnetic Reso | 2018 |
Uptake of Pineal Gland Visible on 18F-DOPA PET/CT With Last Generation of SiPM PET/CT.
Topics: Adolescent; Astrocytoma; Biological Transport; Dihydroxyphenylalanine; Female; Humans; Pineal Gland; | 2020 |
High-grade glioma radiation therapy target volumes and patterns of failure obtained from magnetic resonance imaging and 18F-FDOPA positron emission tomography delineations from multiple observers.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Contrast Media; Dihydroxyphenylalanine; Female; Fluorine | 2013 |
Intra-individual comparison of ¹⁸F-FET and ¹⁸F-DOPA in PET imaging of recurrent brain tumors.
Topics: Astrocytoma; Brain Neoplasms; Dihydroxyphenylalanine; Glioblastoma; Humans; Neoplasm Recurrence, Loc | 2014 |
Value of 18F-3,4-dihydroxyphenylalanine PET/MR image fusion in pediatric supratentorial infiltrative astrocytomas: a prospective pilot study.
Topics: Adolescent; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Child; Dihydroxyphenylalanine; Disease | 2014 |
Impact of 3,4-dihydroxy-6-18F-fluoro-L-phenylalanine PET/CT on managing patients with brain tumors: the referring physician's perspective.
Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Dihydroxyphenylalanine; Female; Follow | 2012 |
Inhibition of growth by 6-hydroxydopamine in cultured cells of neuronal and nonneuronal origin.
Topics: Alcohol Oxidoreductases; Animals; Astrocytoma; Carbon Isotopes; Cell Division; Cell Line; Cell Membr | 1973 |