Page last updated: 2024-10-18

dihydroxyphenylalanine and Argentaffinoma

dihydroxyphenylalanine has been researched along with Argentaffinoma in 28 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Research Excerpts

ExcerptRelevanceReference
"In Canada, staging of carcinoid tumors is largely based on computed tomography (CT) imaging sometimes complemented with somatostatin receptor scintigraphy (SRS)."1.38PET/CT using ¹⁸F-FDOPA provides improved staging of carcinoid tumor patients in a Canadian setting. ( Chirakal, R; Gulenchyn, KY; Jager, PL; Major, P; Reid, R; Yakemchuk, VN, 2012)
"Seventy-seven consecutive carcinoid patients who underwent an 18F-dopa PET scan in two previously published studies were analysed."1.37Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour. ( Brouwers, AH; de Jong, JR; de Vries, EG; Dierckx, RA; Fiebrich, HB; Kema, IP; Koopmans, KP; Links, TP; Sluiter, W; Walenkamp, AM, 2011)
"We report the case of a carcinoid tumor with suspicion of recurrence on biology."1.36[Recurrent carcinoid tumor and 18F-DOPA PET]. ( Cavet, M; Dousset, B; Faraggi, M; Hignette, C; Modis, C; Richard, B; Tenenbaum, F, 2010)
"The greatest impact was observed for carcinoid tumors (50%: 11 of 22) and was clinically relevant in every case, followed by occult endocrine tumors (16%: four of 25), and was clinically relevant in three of the four cases, and noncarcinoid tumors (13%: 3 of 22), clinically relevant in only one case."1.35Impact of fluorodihydroxyphenylalanine-18F positron emission tomography on management of adult patients with documented or occult digestive endocrine tumors. ( Bouchard, P; Duron, F; Grangé, JD; Houry, S; Huchet, V; Kerrou, K; Lotz, JP; Montravers, F; Nataf, V; Rougier, P; Ruszniewski, P; Talbot, JN, 2009)
"Distinguishing a SPM from carcinoid lesions is therefore important."1.35Combining 6-fluoro-[18F]l-dihydroxyphenylalanine and [18F]fluoro-2-deoxy-d-glucose positron emission tomography for distinction of non-carcinoid malignancies in carcinoid patients. ( Brouwers, AH; de Vries, EG; Fiebrich, HB; Koopmans, KP, 2009)
"In all carcinoid patients (18)F-DOPA PET and (11)C-5-HTP PET detected more lesions than SRS (P < ."1.35Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography. ( Brouwers, AH; de Vries, EG; Elsinga, PH; Jager, PL; Kema, IP; Koopmans, KP; Neels, OC; Sluiter, WJ; Vanghillewe, K, 2008)
"Conversely, in noncarcinoid tumors, the extent of the disease was more accurately evaluated in all cases by (111)In-pentetreotide SRS than by (18)F-FDOPA PET."1.33Can fluorodihydroxyphenylalanine PET replace somatostatin receptor scintigraphy in patients with digestive endocrine tumors? ( Aide, N; de Beco, V; Grahek, D; Grangé, JD; Gutman, F; Kerrou, K; Lotz, JP; Montravers, F; Ruszniewski, P; Talbot, JN, 2006)
"The localization of carcinoids in the gastrointestinal tract is frequently difficult if not impossible with the imaging procedures used to date."1.30Imaging of a metastatic gastrointestinal carcinoid by F-18-DOPA positron emission tomography. ( Hoegerle, S; Kraft, A; Moser, E; Nitzsche, EU; Schneider, B, 1999)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19908 (28.57)18.7374
1990's1 (3.57)18.2507
2000's11 (39.29)29.6817
2010's8 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El Ghannudi, S1
Ben Abdelghani, M1
Germain, P1
Blondet, C1
Romain, B1
Imperiale, A2
Zanzi, I1
Warner, RR1
Santhanam, P1
Taïeb, D1
Acevedo-Báñez, I1
Tirado-Hospital, JL1
Muñiz-Grijalvo, O1
Mangas-Cruz, MA1
García-Gómez, FJ1
Helali, M1
Heimburger, C1
Rohr, S1
Goichot, B1
Koornstra, JJ1
de Vries, EG7
Porte, RJ1
Fiebrich, HB3
Brouwers, AH4
Links, TP2
Montravers, F3
Kerrou, K3
Nataf, V2
Huchet, V1
Lotz, JP2
Ruszniewski, P2
Rougier, P1
Duron, F1
Bouchard, P1
Grangé, JD2
Houry, S1
Talbot, JN3
Koopmans, KP5
Cavet, M1
Tenenbaum, F1
Hignette, C1
Modis, C1
Richard, B1
Faraggi, M1
Dousset, B1
de Jong, JR1
Kema, IP3
Sluiter, W1
Dierckx, RA1
Walenkamp, AM1
Yakemchuk, VN1
Jager, PL4
Chirakal, R1
Reid, R1
Major, P1
Gulenchyn, KY1
SJOERDSMA, A1
OATES, JA1
ZALTZMAN, P1
UDENFRIEND, S1
GEFFROY, Y1
CARTIER, P1
LEMOINE, P1
FABLET, J1
MOREAU, J1
MALANDRIN, C1
LEGRAND, M1
HAGEN, P1
GJESSING, LR1
NICHOLSON, GI1
IRVINE, RO1
Elsinga, PH2
Neels, OC2
Sluiter, WJ2
van der Horst-Schrivers, AN1
Grahek, D2
de Beco, V2
Aide, N1
Gutman, F2
Balard, M1
Dubois, S1
Morel, O1
Rodien, P1
Illouz, F1
Girault, S1
Cahouet, A1
Lacoeuille, F1
Brousseau, M1
Picquet, J1
Rohmer, V1
Vanghillewe, K1
Sharma, BK1
Smits, BJ1
Robinson, R1
Burns, S1
Trounson, EN1
Hoegerle, S2
Schneider, B1
Kraft, A1
Moser, E2
Nitzsche, EU1
Altehoefer, C1
Ghanem, N1
Koehler, G1
Waller, CF1
Scheruebl, H1
Nitzsche, E1
Feldman, JM1
Butler, SS1
Chapman, BA1
Simpson, AJ1

Reviews

2 reviews available for dihydroxyphenylalanine and Argentaffinoma

ArticleYear
Role of (18) F-FDOPA PET/CT imaging in endocrinology.
    Clinical endocrinology, 2014, Volume: 81, Issue:6

    Topics: Adrenal Gland Neoplasms; Carbidopa; Carcinoid Tumor; Carcinoma, Neuroendocrine; Dihydroxyphenylalani

2014
The carcinoid tumor, syndrome and spectrum. A review of the literature.
    North Carolina medical journal, 1969, Volume: 30, Issue:11

    Topics: Antineoplastic Agents; Carcinoid Tumor; Cyproheptadine; Dihydroxyphenylalanine; Epinephrine; Ergolin

1969

Other Studies

26 other studies available for dihydroxyphenylalanine and Argentaffinoma

ArticleYear
Cardiac Metastases of Small-Bowel Carcinoid
    Circulation. Cardiovascular imaging, 2019, Volume: 12, Issue:2

    Topics: Adult; Carcinoid Heart Disease; Carcinoid Tumor; Dihydroxyphenylalanine; Humans; Intestinal Neoplasm

2019
Observations on the effects of lithium on carcinoid tumors.
    Pancreas, 2013, Volume: 42, Issue:6

    Topics: Bone Neoplasms; Carcinoid Tumor; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Humans; Lithium Com

2013
18F-DOPA vs. 18F-FDG PET/CT in the ectopic ACTH syndrome due to pulmonary carcinoid tumor.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2015, Volume: 62, Issue:4

    Topics: ACTH Syndrome, Ectopic; Adult; Carcinoid Tumor; Dihydroxyphenylalanine; Fluorine Radioisotopes; Fluo

2015
Small Bowel Carcinoid: The "Dancing Bowel Sign" on 18F-FDOPA PET/CT.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:12

    Topics: Adult; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Intestinal N

2016
Improvements in small bowel carcinoid diagnosis and staging: 18F-DOPA PET, capsule endoscopy and double balloon enteroscopy.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2009, Volume: 41, Issue:7

    Topics: Capsule Endoscopy; Carcinoid Tumor; Cone-Beam Computed Tomography; Dihydroxyphenylalanine; Fluorine

2009
Images in cardiovascular medicine: myocardial metastases of carcinoid visualized by 18F-dihydroxy-phenyl-alanine positron emission tomography.
    Circulation, 2008, Oct-07, Volume: 118, Issue:15

    Topics: Carcinoid Heart Disease; Carcinoid Tumor; Dihydroxyphenylalanine; Dopamine Agents; Fluorodeoxyglucos

2008
Impact of fluorodihydroxyphenylalanine-18F positron emission tomography on management of adult patients with documented or occult digestive endocrine tumors.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:4

    Topics: Adult; Biopsy; Carcinoid Tumor; Dihydroxyphenylalanine; Endocrine Gland Neoplasms; Fluorodeoxyglucos

2009
Combining 6-fluoro-[18F]l-dihydroxyphenylalanine and [18F]fluoro-2-deoxy-d-glucose positron emission tomography for distinction of non-carcinoid malignancies in carcinoid patients.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:13

    Topics: Adenocarcinoma; Aged; Carcinoid Tumor; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluo

2009
[Recurrent carcinoid tumor and 18F-DOPA PET].
    Gastroenterologie clinique et biologique, 2010, Volume: 34, Issue:3

    Topics: Biomarkers, Tumor; Carcinoid Tumor; Colonic Neoplasms; Dihydroxyphenylalanine; Fluorine Radioisotope

2010
Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour.
    European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Biological Transport; Carcinoid Tumor; Dihydroxyphenylalanine; Endocrine Gl

2011
PET/CT using ¹⁸F-FDOPA provides improved staging of carcinoid tumor patients in a Canadian setting.
    Nuclear medicine communications, 2012, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Canada; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Fluorine Ra

2012
Serotonin synthesis in carcinoid patients. Its inhibition by alpha-methyl-dopa, with measurement of associated increases in urinary 5-hydroxytryptophan.
    The New England journal of medicine, 1960, Sep-22, Volume: 263

    Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Carcinoma, Neuroendocrine; Dihydroxyphenylalanine; Humans; Mal

1960
[Trial of alpha-methyl-dopa in a case of carcinoidosis].
    Pathologie et biologie, 1962, Volume: 10

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Humans; Methyldopa; Serotonin; Tryptophan

1962
Observations on the substrate specificity of DOPA decarboxylase from ox adrenal medulla, human phaeochromocytoma and human argentaffinoma.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: 5-Hydroxytryptophan; Adrenal Medulla; Carcinoid Tumor; Dihydroxyphenylalanine; Dopa Decarboxylase; H

1962
STUDIES OF FUNCTIONAL NEURAL TUMORS. V. URINARY EXCRETION OF 3-METHOXY-4HYDROXYPHENYL-LACTIC ACID.
    Scandinavian journal of clinical and laboratory investigation, 1963, Volume: 15

    Topics: Acetates; Adrenal Gland Neoplasms; Butyrates; Carcinoid Tumor; Child; Chromatography; Dihydroxypheny

1963
Effect of methyldopa in carcinoid disease.
    British medical journal, 1962, Oct-13, Volume: 2, Issue:5310

    Topics: Carcinoid Tumor; Carcinoma, Neuroendocrine; Dihydroxyphenylalanine; Humans; Malignant Carcinoid Synd

1962
Staging of carcinoid tumours with 18F-DOPA PET: a prospective, diagnostic accuracy study.
    The Lancet. Oncology, 2006, Volume: 7, Issue:9

    Topics: Adult; Aged; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Humans; Male;

2006
Can fluorodihydroxyphenylalanine PET replace somatostatin receptor scintigraphy in patients with digestive endocrine tumors?
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:9

    Topics: Adult; Aged; Carcinoid Tumor; Digestive System Neoplasms; Dihydroxyphenylalanine; Endocrine Gland Ne

2006
Safety of 18F-DOPA injection for PET of carcinoid tumor.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:10

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Injections, Intravenous; Ma

2006
[Gastroenteropancreatic neuroendocrine tumours (carcinoid tumours): definition, clinical aspects, diagnosis and therapy].
    Nederlands tijdschrift voor geneeskunde, 2006, Oct-28, Volume: 150, Issue:43

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Gastrointestinal Neoplasms; Humans; Pancreatic Neoplasms; P

2006
A Pulmonary adrenocorticotropin-secreting carcinoid tumor localized by 6-Fluoro-[18F]L-dihydroxyphenylalanine positron emission/computed tomography imaging in a patient with Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:12

    Topics: Adolescent; Adrenocorticotropic Hormone; Carcinoid Tumor; Cushing Syndrome; Dihydroxyphenylalanine;

2007
Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Mar-20, Volume: 26, Issue:9

    Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Adult; Aged; Carbon Radioisotopes; Carcinoid Tumor; Dihydr

2008
Carcinoid tumour secreting dopa.
    British medical journal (Clinical research ed.), 1984, Apr-14, Volume: 288, Issue:6424

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Female; Humans; Liver Neoplasms; Middle Aged

1984
Imaging of a metastatic gastrointestinal carcinoid by F-18-DOPA positron emission tomography.
    Nuklearmedizin. Nuclear medicine, 1999, Volume: 38, Issue:4

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Fluorine Radioisotopes; Gastrointestinal Neoplasms; Humans;

1999
Whole-body 18F dopa PET for detection of gastrointestinal carcinoid tumors.
    Radiology, 2001, Volume: 220, Issue:2

    Topics: Adult; Aged; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Fluorodeoxyglu

2001
Interference with measurement of 3-methoxy-4-hydroxymandelic acid and 5-hydroxyindoleacetic acid by reducing metabolites.
    Clinical chemistry, 1974, Volume: 20, Issue:5

    Topics: Aged; Alkaptonuria; Aspirin; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Humans; Indoleacetic A

1974