Page last updated: 2024-10-18

dihydroxyphenylalanine and Anoxemia

dihydroxyphenylalanine has been researched along with Anoxemia in 41 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Research Excerpts

ExcerptRelevanceReference
"The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)."7.67The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986)
"In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia."7.66Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982)
"We examined the effects of hypoxia (8% O2) on in vivo tyrosine hydroxylation, a rate-limiting step for catecholamine synthesis, in the rat adrenal gland."3.68Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions. ( Fujiwara, M; Hamahata, K; Hasegawa, H; Hayashi, Y; Koshimura, K; Lee, K; Miwa, S; Watanabe, Y, 1990)
"The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)."3.67The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986)
" Using this method, we investigated the effects of immobilization stress, reserpine, and hypoxia on in vivo activities of tyrosine hydroxylase in the adrenal gland."3.67A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland. ( Fujiwara, M; Hamahata, K; Hayashi, Y; Kamel, A; Koshimura, K; Lee, K; Miwa, S, 1988)
"In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia."3.66Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199033 (80.49)18.7374
1990's5 (12.20)18.2507
2000's2 (4.88)29.6817
2010's0 (0.00)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Jiang, S1
Li, X1
Zhang, F1
Mao, J1
Cao, M1
Zhang, X1
Huang, S1
Duan, X1
Shen, J1
GRAHAM, P1
KAHLSON, G1
ROSENGREN, E1
Ivanov, AI1
Khitrov, NK2
Alaverdia, AM1
Toloknov, AV1
Tezikov, EB1
Hedner, T4
Lundborg, P4
Gautier, H1
Bonora, M1
Claustre, J1
Peyrin, L2
Sakabe, T1
Dahlgren, N1
Carlsson, A8
Siesjö, BK1
Dalmaz, Y1
Pequignot, JM1
Cottet-Emard, JM1
Tammela, O1
Pastuszko, A1
Lajevardi, NS1
Delivoria-Papadopoulos, M1
Wilson, DF1
Serebrovskaya, TV2
Karaban, IN2
Kolesnikova, EE2
Mishunina, TM2
Kuzminskaya, LA2
Serbrovsky, AN1
Swanson, RJ2
Bauer, R1
Brust, P1
Walter, B1
Vorwieger, G1
Bergmann, R1
Füchtner, F1
Steinbach, J1
el-Hallag, E1
Fritz, A1
Johannsen, B1
Zwiener, U1
Beloshitsky, PV1
Ilyin, VN1
Krasuk, AN1
Safronova, OS1
Engel, J4
Brown, RM3
Kehr, W1
Davis, JN3
Lauweryns, JM1
Cokelaere, M1
Deleersynder, M1
Liebens, M1
Burke, RE1
Reches, A1
Hayashi, Y2
Miwa, S4
Lee, K3
Koshimura, K2
Hamahata, K2
Hasegawa, H1
Fujiwara, M6
Watanabe, Y1
Brokaw, JJ1
Hansen, JT1
Christie, DS1
Inoue, M1
Kamel, A1
Rigual, R1
Gonzalez, E1
Gonzalez, C1
Fidone, S1
Brown, R2
David, JN1
Solov'ev, GM1
Matlina, ESh1
Cymerman, A1
Robinson, SM1
McCullough, D1
Walsh, C1
McLelland, J1
Snider, SR2
Lhermitte, F1
Marteau, R1
Degos, CF1
Kassil', GN1
Beleda, RV1
Artamonov, NN1
Zakharova, SI1
Goncharenko, EN1
Dzhanumova, T1
Zhat'kova, GS1
Kudriashov, IuB1
Yates, RD1
Chen, IL1
Duncan, D1
Mascorro, JA1
Debijadji, R1
Perović, L1
Varagić, V1
Stosić, N1

Reviews

2 reviews available for dihydroxyphenylalanine and Anoxemia

ArticleYear
Measurements of monoamine synthesis and turnover with special reference to 5-hydroxytryptamine.
    Advances in biochemical psychopharmacology, 1974, Volume: 10

    Topics: Acetamides; Animals; Benserazide; Benzyl Compounds; Biogenic Amines; Brain; Carboxy-Lyases; Dibenzaz

1974
[Cardiac catecholamines in stress situations].
    Kardiologiia, 1973, Volume: 13, Issue:1

    Topics: Adrenal Glands; Animals; Brain Injuries; Burns; Catecholamines; Cold Temperature; Dihydroxyphenylala

1973

Trials

1 trial available for dihydroxyphenylalanine and Anoxemia

ArticleYear
Geriatric men at altitude: hypoxic ventilatory sensitivity and blood dopamine changes.
    Respiration; international review of thoracic diseases, 2000, Volume: 67, Issue:3

    Topics: Adaptation, Physiological; Adult; Age Factors; Aging; Altitude; Analysis of Variance; Dihydroxypheny

2000

Other Studies

38 other studies available for dihydroxyphenylalanine and Anoxemia

ArticleYear
Manganese Dioxide-Based Nanocarrier Delivers Paclitaxel to Enhance Chemotherapy against Orthotopic Glioma through Hypoxia Relief.
    Small methods, 2022, Volume: 6, Issue:7

    Topics: Animals; Dihydroxyphenylalanine; Glioma; Hypoxia; Manganese Compounds; Oxides; Paclitaxel; Rats; Tum

2022
HISTAMINE FORMATION IN PHYSICAL EXERCISE, ANOXIA AND UNDER THE INFLUENCE OF ADRENALINE AND RELATED SUBSTANCES.
    The Journal of physiology, 1964, Volume: 172

    Topics: Adrenal Medulla; Adrenalectomy; Altitude; Cortisone; Diaphragm; Dihydroxyphenylalanine; Dopamine; Ep

1964
[Heart function and the mechanisms of its regulation in modelling adaptation to hypoxia by 2,4-dinitrophenol administration].
    Kardiologiia, 1983, Volume: 23, Issue:1

    Topics: Adaptation, Physiological; Animals; Dihydroxyphenylalanine; Dinitrophenols; Disease Models, Animal;

1983
[Trace processes in the circulatory system of rats during prolonged adaptation to hypoxia].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1981, Volume: 67, Issue:2

    Topics: Adaptation, Physiological; Animals; Blood Pressure; Cardiomegaly; Dihydroxyphenylalanine; Heart; Hea

1981
Catecholamine metabolism in neonatal rat brain during asphyxia and recovery.
    Acta physiologica Scandinavica, 1980, Volume: 109, Issue:2

    Topics: Animals; Animals, Newborn; Asphyxia; Brain; Brain Stem; Catecholamines; Diencephalon; Dihydroxypheny

1980
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1980, Volume: 49, Issue:5

    Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; D

1980
Free and conjugated catecholamines and metabolites in cat urine after hypoxia.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1982, Volume: 52, Issue:2

    Topics: Adrenal Medulla; Animals; Catecholamines; Cats; Dihydroxyphenylalanine; Dopamine; Epinephrine; Hypox

1982
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
    Acta physiologica Scandinavica, 1982, Volume: 115, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyph

1982
Adrenal response to long-term hypoxia is still increased after carotid body denervation in rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:3

    Topics: Adrenal Glands; alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carotid

1994
Activity of tyrosine hydroxylase in the striatum of newborn piglets in response to hypocapnic hypoxia.
    Journal of neurochemistry, 1993, Volume: 60, Issue:4

    Topics: Animals; Animals, Newborn; Carbon Dioxide; Cerebral Cortex; Corpus Striatum; Dialysis; Dihydroxyphen

1993
Human hypoxic ventilatory response with blood dopamine content under intermittent hypoxic training.
    Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:12

    Topics: Adaptation, Physiological; Adult; Breath Tests; Breathing Exercises; Dihydroxyphenylalanine; Dopamin

1999
Relation between brain tissue pO2 and dopamine synthesis of basal ganglia--a 18FDOPA-PET study in newborn piglets.
    Journal of perinatal medicine, 2000, Volume: 28, Issue:1

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Basal Ganglia; Blood Pressure; Brain; Dihydroxypheny

2000
Effect of hypoxia on monoamine synthesis in brains of developing rats.
    Biology of the neonate, 1977, Volume: 31, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Benzyl Compounds; Brain; Carboxy-Lyases; Dihydroxyph

1977
Effect of hypoxia on monoamine synthesis in brains of developing rats. II. Different length of exposure.
    Biology of the neonate, 1977, Volume: 32, Issue:3-4

    Topics: Animals; Brain; Dihydroxyphenylalanine; Hypoxia; Rats; Serotonin; Time Factors; Tryptophan; Tryptoph

1977
Effect of hypoxia on monoamine synthesis in brains of developing rats. III. Various O2 levels.
    Biology of the neonate, 1978, Volume: 34, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Female; Hypoxia; Nore

1978
Functional and biochemical aspects of catecholamine metabolism in brain under hypoxia.
    Brain research, 1975, Mar-07, Volume: 85, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Brain; Catecholamin

1975
Adaptation of brain monoamine synthesis to hypoxia in the rat.
    Journal of applied physiology, 1975, Volume: 39, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Brain Chemistry; Chromatography, Ion Exchange;

1975
Intrapulmonary neuro-epithelial bodies in newborn rabbits. Influence of hypoxia, hyperoxia, hypercapnia, nicotine, reserpine, L-DOPA and 5-HTP.
    Cell and tissue research, 1977, Sep-05, Volume: 182, Issue:4

    Topics: Animals; Chemoreceptor Cells; Dihydroxyphenylalanine; Exocytosis; Hypercapnia; Hypoxia; Lung; Micros

1977
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
    Brain research. Developmental brain research, 1991, Aug-19, Volume: 61, Issue:2

    Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; B

1991
Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions.
    Journal of neurochemistry, 1990, Volume: 54, Issue:4

    Topics: Adrenal Glands; Animals; Biopterins; Brain; Denervation; Dihydroxyphenylalanine; Hypoxia; Kinetics;

1990
The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Hyd

1986
The effects of hypoxia on catecholamine dynamics in the rat carotid body.
    Journal of the autonomic nervous system, 1985, Volume: 13, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carotid Body; Catecholamines; Dihydroxyphenylalanine; Dopam

1985
Effects of hypoxia on the activities of noradrenergic and dopaminergic neurons in the rat brain.
    Journal of neurochemistry, 1986, Volume: 47, Issue:1

    Topics: alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenyla

1986
A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland.
    Analytical biochemistry, 1988, Volume: 168, Issue:1

    Topics: Adrenal Glands; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dihydro

1988
Synthesis and release of catecholamines by the cat carotid body in vitro: effects of hypoxic stimulation.
    Brain research, 1986, May-21, Volume: 374, Issue:1

    Topics: Animals; Carotid Body; Carotid Sinus; Catecholamines; Cats; Dihydroxyphenylalanine; Dopamine; Electr

1986
Dopa reversal of hypoxia-induced disruption of the conditioned avoidance response.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:5

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atmosphere; Avoidance Learning; Brain; Dihydr

1973
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
    Journal of neurochemistry, 1973, Volume: 21, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry;

1973
Evidence for catecholamine involvement in the suppression of locomotor activity due to hypoxia.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:10

    Topics: Amphetamine; Animals; Apomorphine; Clonidine; Dihydroxyphenylalanine; Female; Hypoxia; Mice; Motor A

1973
Alteration of rat brain catecholamine metabolism during exposure to hypobaric hypoxia.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:4

    Topics: Altitude; Animals; Brain; Brain Chemistry; Catecholamines; Chromatography, Ion Exchange; Dihydroxyph

1972
Granular "endocrine" cells in avian respiratory epithelia.
    Cell and tissue research, 1974, Volume: 153, Issue:2

    Topics: Animals; Animals, Newborn; Axons; Bronchi; Chick Embryo; Chickens; Cytoplasmic Granules; Dihydroxyph

1974
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. I. The adrenal medulla.
    Journal of neural transmission, 1974, Volume: 35, Issue:4

    Topics: Adrenal Medulla; Animals; Dihydroxyphenylalanine; Dopamine; Electroshock; Epinephrine; Humans; Hyper

1974
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. II. The central nervous system.
    Journal of neural transmission, 1974, Volume: 35, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Depression, Chemi

1974
[Pharmacologic analysis of a new case of postanoxic intention and action myoclonus].
    Revue neurologique, 1972, Volume: 126, Issue:2

    Topics: Adult; Anesthesia, General; Butyrophenones; Catecholamines; Coma; Dihydroxyphenylalanine; Endoscopy;

1972
Effect of hypoxia on tyrosine and tryptophan hydroxylation in unanaesthetized rat brain.
    Journal of neurochemistry, 1973, Volume: 20, Issue:3

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; Dihydroxyphenylalanin

1973
[Prediction of autonomic reactions during extreme actions on the body].
    Doklady Akademii nauk SSSR, 1972, May-11, Volume: 204, Issue:2

    Topics: 17-Hydroxycorticosteroids; Altitude; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine;

1972
[Role of endogenous dopamine in the radiation-protective effect of radioprotectors].
    Doklady Akademii nauk SSSR, 1972, Jul-11, Volume: 205, Issue:2

    Topics: Adrenal Glands; Animals; Cysteamine; Dihydroxyphenylalanine; Dopamine; Hypoxia; Intestine, Small; Li

1972
The mechanism of storage and release of catecholamines from chromaffin cells.
    Texas reports on biology and medicine, 1971, Volume: 29, Issue:2

    Topics: Animals; Carotid Body; Catecholamines; Chromaffin System; Cytoplasmic Granules; Dihydroxyphenylalani

1971
Effect of hypoxic hypoxia on the catecholamine content and some cytochemical changes in the hypothalamus of the cat.
    Aerospace medicine, 1969, Volume: 40, Issue:5

    Topics: Aerospace Medicine; Altitude; Animals; Atmospheric Pressure; Catecholamines; Cats; Dihydroxyphenylal

1969