dihydroxyphenylalanine has been researched along with Amino Acid Metabolism Disorders, Inborn in 3 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, PW | 1 |
| Lee, NC | 2 |
| Chien, YH | 2 |
| Wu, JY | 1 |
| Wang, PC | 1 |
| Hwu, WL | 2 |
| Muramatsu, S | 1 |
| Tseng, SH | 1 |
| Tzen, KY | 1 |
| Snyder, RO | 1 |
| Byrne, BJ | 1 |
| Tai, CH | 1 |
| Wu, RM | 1 |
| Curtius, HC | 1 |
| Baerlocher, K | 1 |
| Völlmin, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| SIngle-Stage, Open-Label, Safety and Efficacy Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase by Magnetic Resonance MR-guided Infusion Into Midbrain in Pediatric Patients With AADC Deficiency[NCT02852213] | Phase 1 | 31 participants (Anticipated) | Interventional | 2016-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dihydroxyphenylalanine and Amino Acid Metabolism Disorders, Inborn
| Article | Year |
|---|---|
Gene therapy for aromatic L-amino acid decarboxylase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Antibodies; Aromatic-L-Amino-Acid Decarboxylases; Child; Child | 2012 |
2 other studies available for dihydroxyphenylalanine and Amino Acid Metabolism Disorders, Inborn
| Article | Year |
|---|---|
Diagnosis of aromatic L-amino acid decarboxylase deficiency by measuring 3-O-methyldopa concentrations in dried blood spots.
Topics: Amino Acid Metabolism, Inborn Errors; Aromatic-L-Amino-Acid Decarboxylases; Calibration; Child; Chil | 2014 |
Pathogenesis of phenylketonuria: inhibition of DOPA and catecholamine synthesis in patients with phenylketonuria.
Topics: Amino Acid Metabolism, Inborn Errors; Catecholamines; Catechols; Child; Child, Preschool; Deuterium; | 1972 |