dihydroxyphenylalanine has been researched along with Ambulation Disorders, Neurologic in 5 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Braak's staging concept of Lewy body disease pathogenesis is based on a spatiotemporal sequence of alpha-synuclein deposition, with autonomic nervous system involvement before synucleinopathy in substantia nigra neurons." | 3.78 | Sympathetic noradrenergic before striatal dopaminergic denervation: relevance to Braak staging of synucleinopathy. ( Goldstein, DS; Holmes, C; Park, MY; Sewell, L; Sharabi, Y, 2012) |
| "Background: Parkinson's disease (PD) patients who develop freezing of gait (FOG) have reduced mobility and independence." | 1.72 | Neurodegeneration of the Globus Pallidus Internus as a Neural Correlate to Dopa-Response in Freezing of Gait. ( Benitez, A; Bonilha, L; Jensen, JH; Keith, K; Lench, DH; Padgett, L; Ramakrishnan, V; Revuelta, GJ; Wilson, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourilhon, J | 2 |
| Olivier, C | 2 |
| You, H | 1 |
| Collomb-Clerc, A | 1 |
| Grabli, D | 2 |
| Belaid, H | 2 |
| Mullie, Y | 2 |
| François, C | 1 |
| Czernecki, V | 2 |
| Lau, B | 1 |
| Pérez-García, F | 1 |
| Bardinet, E | 1 |
| Fernandez-Vidal, S | 1 |
| Karachi, C | 2 |
| Welter, ML | 2 |
| Cherif, S | 1 |
| Lench, DH | 1 |
| Keith, K | 1 |
| Wilson, S | 1 |
| Padgett, L | 1 |
| Benitez, A | 1 |
| Ramakrishnan, V | 1 |
| Jensen, JH | 1 |
| Bonilha, L | 1 |
| Revuelta, GJ | 1 |
| Ehgoetz Martens, KA | 1 |
| Ellard, CG | 1 |
| Almeida, QJ | 1 |
| Goldstein, DS | 1 |
| Holmes, C | 1 |
| Sewell, L | 1 |
| Park, MY | 1 |
| Sharabi, Y | 1 |
3 trials available for dihydroxyphenylalanine and Ambulation Disorders, Neurologic
| Article | Year |
|---|---|
Pedunculopontine and Cuneiform Nuclei Deep Brain Stimulation for Severe Gait and Balance Disorders in Parkinson's Disease: Interim Results from a Randomized Double-Blind Clinical Trial.
Topics: Deep Brain Stimulation; Dihydroxyphenylalanine; Gait; Gait Disorders, Neurologic; Humans; Parkinson | 2022 |
Stimulation of the pedunculopontine and cuneiform nuclei for freezing of gait and falls in Parkinson disease: Cross-over single-blinded study and long-term follow-up.
Topics: Deep Brain Stimulation; Dihydroxyphenylalanine; Follow-Up Studies; Gait; Gait Disorders, Neurologic; | 2022 |
Anxiety-provoked gait changes are selectively dopa-responsive in Parkinson's disease.
Topics: Aged; Anxiety; Biomechanical Phenomena; Case-Control Studies; Dihydroxyphenylalanine; Dopamine Agent | 2015 |
2 other studies available for dihydroxyphenylalanine and Ambulation Disorders, Neurologic
| Article | Year |
|---|---|
Neurodegeneration of the Globus Pallidus Internus as a Neural Correlate to Dopa-Response in Freezing of Gait.
Topics: Dihydroxyphenylalanine; Dopamine; Gait; Gait Disorders, Neurologic; Globus Pallidus; Humans; Parkins | 2022 |
Sympathetic noradrenergic before striatal dopaminergic denervation: relevance to Braak staging of synucleinopathy.
Topics: Aged; alpha-Synuclein; Autonomic Denervation; Dementia; Dihydroxyphenylalanine; Disease Progression; | 2012 |