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dihydroxyphenylalanine and Albinism

dihydroxyphenylalanine has been researched along with Albinism in 22 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Albinism: General term for a number of inherited defects of amino acid metabolism in which there is a deficiency or absence of pigment in the eyes, skin, or hair.

Research Excerpts

ExcerptRelevanceReference
"5-S-cysteinyldopa concentrations were determined by high-pressure liquid chromatography and electrochemical detection in plasma from normally pigmented patients and patients with oculocutaneous albinism, both tyrosinase-positive and tyrosinase-negative."7.67Plasma 5-S-cysteinyldopa concentrations in oculocutaneous albinism. ( Hunter, JA; Jay, B; Nimmo, JE; Percy-Robb, IW; Phillips, CI; Taylor, WO, 1985)
"5-S-cysteinyldopa concentrations were determined by high-pressure liquid chromatography and electrochemical detection in plasma from normally pigmented patients and patients with oculocutaneous albinism, both tyrosinase-positive and tyrosinase-negative."3.67Plasma 5-S-cysteinyldopa concentrations in oculocutaneous albinism. ( Hunter, JA; Jay, B; Nimmo, JE; Percy-Robb, IW; Phillips, CI; Taylor, WO, 1985)
"Pregnancy was therefore continued and a normal male infant was born."1.29Prenatal diagnosis of oculocutaneous albinism by analysis of the fetal tyrosinase gene. ( Aozaki, R; Hikiji, K; Kawaguchi, R; Niizeki, H; Nishikawa, T; Shimizu, H; Suzumori, K, 1994)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199020 (90.91)18.7374
1990's2 (9.09)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HU, F2
FOSNAUGH, RP1
LESNEY, PF1
MISHIMA, Y2
Ehinger, B1
Rosengren, E5
Hansson, C4
Poulsen, J2
Rorsman, H4
Fehling, C1
Murray, M1
Pawelek, JM1
Lamoreux, ML1
Hanifin, JM1
Prescott, GH1
Tongue, AC1
Shimizu, H1
Niizeki, H1
Suzumori, K1
Aozaki, R1
Kawaguchi, R1
Hikiji, K1
Nishikawa, T1
Ilia, M1
Jeffery, G1
Jimbow, K1
Fitzpatrick, TB1
Szabo, G1
Hori, Y1
Nimmo, JE1
Hunter, JA1
Percy-Robb, IW1
Jay, B1
Phillips, CI1
Taylor, WO1
Carstam, R2
Krook, G1
Wirestrand, LE1
Gilhar, A1
Pillar, T1
Eidelman, S1
Etzioni, A1
Riley, PA1
Witkop, CJ1
Hill, CW1
Desnick, S1
Thies, JK1
Thorn, HL1
Jenkins, M1
White, JG1
Smith-Gill, SJ1
Richards, CM1
Nace, GW1
Huriez, C1
Gaudin, D1
Fellman, JH1
Jung, EG2
Anton-Lamprecht, I2

Trials

1 trial available for dihydroxyphenylalanine and Albinism

ArticleYear
[Copper metabolism disorders in vitiligo].
    Annales de dermatologie et de syphiligraphie, 1972, Volume: 99, Issue:1

    Topics: Albinism; Autoimmune Diseases; Catechol Oxidase; Ceruloplasmin; Clinical Trials as Topic; Copper; Di

1972

Other Studies

21 other studies available for dihydroxyphenylalanine and Albinism

ArticleYear
Studies on albinism. The demonstration of dopa-positive melanocytes in albino skin.
    Archives of dermatology, 1961, Volume: 83

    Topics: Albinism; Chromatophores; Dihydroxyphenylalanine; Humans; Melanocytes; Skin

1961
ELECTRON MICROSCOPIC CYTOCHEMISTRY OF MELANOSOMES AND MITOCHONDRIA.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1964, Volume: 12

    Topics: Albinism; Ammonium Compounds; Black People; Dihydroxyphenylalanine; Electrons; Fishes; Histocytochem

1964
DOPA in ocular pigment cells in mammalian albinotic embryos.
    Experientia, 1967, Jun-15, Volume: 23, Issue:6

    Topics: Albinism; Animals; Ciliary Body; Dihydroxyphenylalanine; Eye; Guinea Pigs; Histocytochemistry; Iris;

1967
DOPA in sympathetic nerve tissue--a possible source of serum DOPA in albino animals.
    Acta dermato-venereologica, 1981, Volume: 61, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Albinism; Animals; Dihydroxyphenylalanine; Dopamine; Epinephrine; Ga

1981
Formation of glutathionedopa in albino rats after DOPA injection.
    Acta dermato-venereologica, 1981, Volume: 61, Issue:4

    Topics: Albinism; Animals; Cattle; Choroid; Chromatography, High Pressure Liquid; Cysteinyldopa; Dihydroxyph

1981
New regulatory factors for melanogenesis: developmental changes in neonatal mice of various genotypes.
    Developmental biology, 1983, Volume: 100, Issue:1

    Topics: Albinism; Animals; Animals, Newborn; Dihydroxyphenylalanine; Indoles; Melanins; Mice; Mice, Inbred A

1983
Yellow mutant albinism: cytochemical, ultrastructural, and genetic characterization suggesting multiple allelism.
    American journal of human genetics, 1980, Volume: 32, Issue:3

    Topics: Adult; Aged; Albinism; Alleles; Dihydroxyphenylalanine; Female; Genotype; Hair; Humans; Male; Melani

1980
Prenatal diagnosis of oculocutaneous albinism by analysis of the fetal tyrosinase gene.
    The Journal of investigative dermatology, 1994, Volume: 103, Issue:1

    Topics: Albinism; Base Sequence; Child; Dihydroxyphenylalanine; DNA; Family Health; Female; Fetal Diseases;

1994
Retinal mitosis is regulated by dopa, a melanin precursor that may influence the time at which cells exit the cell cycle: analysis of patterns of cell production in pigmented and albino retinae.
    The Journal of comparative neurology, 1999, Mar-15, Volume: 405, Issue:3

    Topics: Albinism; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Embryo, Mammalian;

1999
Histopathology of functional pigmentary disorders.
    Cutis, 1978, Volume: 21, Issue:2

    Topics: Albinism; Animals; Cricetinae; Dihydroxyphenylalanine; Female; Humans; Infant; Melanocytes; Melanosi

1978
Congenital circumscribed hypomelanosis: a characterization based on electron microscopic study of tuberous sclerosis, nevus depigmentosus, and piebaldism.
    The Journal of investigative dermatology, 1975, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Albinism; Black People; Child; Child, Preschool; Dihydroxyphenylalanine; Female;

1975
Plasma 5-S-cysteinyldopa concentrations in oculocutaneous albinism.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:2

    Topics: Albinism; Animals; Chromatography, High Pressure Liquid; Cysteinyldopa; Dihydroxyphenylalanine; Elec

1985
Oxidation of dopa in human albinism.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:5

    Topics: Adult; Albinism; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Indoles; Osmolar Concentrati

1985
Oxidation of dopa in the skin of black and albino mice.
    Acta dermato-venereologica, 1986, Volume: 66, Issue:5

    Topics: Albinism; Animals; Cysteinyldopa; Dihydroxyphenylalanine; Female; In Vitro Techniques; Male; Melanin

1986
Vitiligo and idiopathic guttate hypomelanosis. Repigmentation of skin following engraftment onto nude mice.
    Archives of dermatology, 1989, Volume: 125, Issue:10

    Topics: Adult; Albinism; Animals; Dihydroxyphenylalanine; Humans; Melanocytes; Mice; Mice, Inbred BALB C; Mi

1989
A study of the distribution of epidermal dendritic cells in pigmented and unpigmented skin.
    The Journal of investigative dermatology, 1967, Volume: 48, Issue:1

    Topics: Adenosine Triphosphatases; Albinism; Animals; Dendrites; Dihydroxyphenylalanine; Guinea Pigs; Histoc

1967
Ophthalmologic, biochemical, platelet, and ultrastructural defects in the various types of oculocutaneous albinism.
    The Journal of investigative dermatology, 1973, Volume: 60, Issue:6

    Topics: Albinism; Blood Platelet Disorders; Blood Platelets; Bone Marrow; Bone Marrow Cells; Dihydroxyphenyl

1973
Genetic and metabolic bases of two "albino" phenotypes in the leopard frog, Rana pipiens.
    The Journal of experimental zoology, 1972, Volume: 180, Issue:2

    Topics: Albinism; Animals; Anura; Catechol Oxidase; Chromatophores; Crosses, Genetic; Culture Techniques; Di

1972
The biosynthesis of DOPA in albino skin.
    Biochimica et biophysica acta, 1967, Jun-13, Volume: 141, Issue:1

    Topics: Albinism; Animals; Carbon Isotopes; Catechol Oxidase; Chelating Agents; Dihydroxyphenylalanine; Elec

1967
Investigation of a case of oculocutaneous albinism.
    Birth defects original article series, 1971, Volume: 7, Issue:8

    Topics: Adult; Albinism; Catechol Oxidase; Catecholamines; Dihydroxyphenylalanine; Eye; Golgi Apparatus; Hum

1971
[Studies on albumin].
    Archiv fur dermatologische Forschung, 1971, Volume: 240, Issue:2

    Topics: Adult; Albinism; Chromatophores; Dihydroxyphenylalanine; Endoplasmic Reticulum; Golgi Apparatus; Hum

1971