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dihydroxyphenylalanine and Aggression

dihydroxyphenylalanine has been researched along with Aggression in 46 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"REM sleep deprivation (REMSD) results in behavioral changes such as the appearance of affective aggression induced by apomorphine (APO) and other dopaminergic agents."3.68Effects of selective adrenoceptor agonists and antagonists on aggressive behavior elicited by apomorphine, DL-dopa and fusaric acid in REM-sleep-deprived rats. ( Troncone, LR; Tufik, S, 1991)
"Fatigue, confusion, and depression were measured on the Profile of Mood States, while barometric pressure and the ANS indices of heart rate and body temperature were also recorded."1.26Alertness and clear thinking as characteristics of high naturally occurring autonomic nervous system arousal. ( Schubert, DS, 1977)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199042 (91.30)18.7374
1990's3 (6.52)18.2507
2000's0 (0.00)29.6817
2010's1 (2.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schlüter, T1
Winz, O1
Henkel, K1
Prinz, S1
Rademacher, L1
Schmaljohann, J1
Dautzenberg, K1
Cumming, P1
Kumakura, Y1
Rex, S1
Mottaghy, FM1
Gründer, G1
Vernaleken, I1
Kantak, KM1
Hegstrand, LR1
Eichelman, B5
Miachon, S1
Rochet, T1
Mathian, B1
Barbagli, B1
Claustrat, B1
Melega, WP1
Raleigh, MJ1
Stout, DB1
Huang, SC1
Phelps, ME1
Pradhan, SN1
Schubert, DS1
Johnson, RL1
Smissman, EE1
Plotnikoff, NP5
Kastin, AJ1
Coy, DH1
Christensen, CW1
Schally, AV1
Spirtes, MA1
Razdan, RK3
Terris, BZ2
Pars, HG2
Dodge, PW2
Dren, AT2
Kyncl, J2
Somani, P1
Handrick, GR2
Dalzell, HC2
Howes, JF2
Plotnikoff, N1
Dodge, P1
Dren, A1
Shoer, L1
Thompson, WR1
Winn, M1
Troncone, LR1
Tufik, S1
Maeda, H1
Maki, S1
Turlapaty, P1
Shibata, S1
Norton, TR1
Kashiwagi, M1
Krsiak, M1
Lycke, E2
Roos, BE2
Dominguez, M1
Longo, VG1
Palermo Neto, J1
Carlini, EA1
Benkert, O2
Renz, A1
Matussek, N2
Senault, B1
Papeschi, R1
Bryson, G2
Reis, DJ1
Butcher, LL1
Dietrich, AP1
Zetler, G1
Otten, U1
Thoa, NB4
Ng, KY1
Kawamura, K1
Yamamoto, H1
Goto, Y1
Kobayashi, M1
Sato, M1
Goldstein, M1
Karczmar, AG1
Scudder, CL1
Richardson, DL1
Johansson, G1
Richardson, JS1
Jacobowitz, D1
Gluba, H1
Eichelman, BS1
Bischoff, F1
Puri, S1
Lal, H2
Patni, SK1
Dandiya, PC1
Randrup, A2
Munkvad, I2
Goodwin, FK1
Murphy, DL1
Brodie, HK1
Bunney, WE1
Ng, LK1
Yen, HC2
Katz, MH2
Krop, S2
Modigh, K1
Nesson, B1
Smith, N1

Reviews

9 reviews available for dihydroxyphenylalanine and Aggression

ArticleYear
Aggression and central neurotransmitters.
    International review of neurobiology, 1975, Volume: 18

    Topics: Acetylcholinesterase; Aggression; Amantadine; Animals; Apomorphine; Brain; Carbachol; Choline O-Acet

1975
Behavioral changes and aggressivity evoked by drugs in mice.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:2

    Topics: Aggression; Animals; Antidepressive Agents; Barbiturates; Behavior, Animal; Benzodiazepinones; Centr

1974
The relationship between brain norepinephrine and aggressive behavior.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Adrenal Glands; Aggression; Amygdala; Animals; Behavior, Animal; Brain; Brain Stem; Cats; Cerebral D

1972
The catecholamines and aggressive behavior.
    Neurosciences research, 1973, Volume: 5, Issue:0

    Topics: Aggression; Amphetamine; Anger; Animals; Behavior, Animal; Brain Stem; Catecholamines; Dihydroxyphen

1973
Brain research and violent behavior. A summary and evaluation of the status of biomedical research on brain and aggressive violent behavior.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Aggression; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Bipolar Disorder; Bra

1974
Interdisciplinary approach to the study of behavior in related mice types.
    Neurosciences research, 1973, Volume: 5, Issue:0

    Topics: Acetylcholine; Acetylcholinesterase; Adaptation, Physiological; Aggression; Animals; Behavior, Anima

1973
Relation of biogenic amines to aggressive behaviour.
    Medical biology, 1974, Volume: 52, Issue:3

    Topics: Acetylcholine; Aggression; Animals; Apomorphine; Cats; Depression, Chemical; Dihydroxyphenylalanine;

1974
Pharmacological studies on the brain mechanisms underlying two forms of behavioral excitation: stereotyped hyperactivity and "rage".
    Annals of the New York Academy of Sciences, 1969, Jul-30, Volume: 159, Issue:3

    Topics: Aggression; Amphetamine; Anger; Animals; Basal Ganglia; Behavior, Animal; Brain; Brain Chemistry; Di

1969
L-DOPA, catecholamines, and behavior: a clinical and biochemical study in depressed patients.
    Biological psychiatry, 1970, Volume: 2, Issue:4

    Topics: Aged; Aggression; Anger; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Carboxy-Lyases; Catecho

1970

Trials

1 trial available for dihydroxyphenylalanine and Aggression

ArticleYear
L-DOPA, catecholamines, and behavior: a clinical and biochemical study in depressed patients.
    Biological psychiatry, 1970, Volume: 2, Issue:4

    Topics: Aged; Aggression; Anger; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Carboxy-Lyases; Catecho

1970

Other Studies

37 other studies available for dihydroxyphenylalanine and Aggression

ArticleYear
The impact of dopamine on aggression: an [18F]-FDOPA PET Study in healthy males.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Oct-23, Volume: 33, Issue:43

    Topics: Adult; Aggression; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; Male; Mesencephalon; P

2013
Facilitation of shock-induced fighting following intraventricular 5,7-dihydroxytryptamine and 6-hydroxydopa.
    Psychopharmacology, 1981, Volume: 74, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Aggression; Analgesics; Animals; Biogenic Amines; Brain Chemistry; Dihydrox

1981
Long-term isolation of Wistar rats alters brain monoamine turnover, blood corticosterone, and ACTH.
    Brain research bulletin, 1993, Volume: 32, Issue:6

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aggression; Animals; Biogenic Monoamines; Brain; C

1993
Ethological and 6-[18F]fluoro-L-DOPA-PET profiles of long-term vulnerability to chronic amphetamine.
    Behavioural brain research, 1997, Volume: 84, Issue:1-2

    Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulan

1997
Alertness and clear thinking as characteristics of high naturally occurring autonomic nervous system arousal.
    The Journal of general psychology, 1977, Volume: 97, Issue:1st Half

    Topics: Adult; Aged; Aggression; Anxiety; Arousal; Atmospheric Pressure; Autonomic Nervous System; Body Temp

1977
Study of the structural requirements for dopa potentiation and oxotremorine antagonism by L-prolyl-L-leucylglycinamide.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:2

    Topics: Aggression; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug Synergism; Humans; Male; Mice; M

1978
Neuropharmacological actions of enkephalin after systemic administration.
    Life sciences, 1976, Oct-15, Volume: 19, Issue:8

    Topics: Aggression; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug Synergism; Humans; Mice; Nerve T

1976
Drugs derived from cannabinoids. 2. Basic esters of nitrogen and carbocyclic analogs.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:4

    Topics: Acoustic Stimulation; Aggression; Analgesics; Animals; Ataxia; Behavior, Animal; Cannabis; Cats; Dih

1976
Drugs derived from cannabinoids. 3. Sulfur analogs, thiopyranobenzopyrans and thienobenzopyrans.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:4

    Topics: Aggression; Analgesics; Animals; Ataxia; Benzopyrans; Cannabis; Cats; Dihydroxyphenylalanine; Dogs;

1976
Drugs derived from cannabinoids. 4. Effect of alkyl substitution in sulfur and carbocyclic analogs.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:4

    Topics: Acoustic Stimulation; Aggression; Analgesics; Animals; Ataxia; Cannabis; Cats; Cyclohexanes; Cyclope

1976
Effects of selective adrenoceptor agonists and antagonists on aggressive behavior elicited by apomorphine, DL-dopa and fusaric acid in REM-sleep-deprived rats.
    Physiology & behavior, 1991, Volume: 50, Issue:1

    Topics: Aggression; Animals; Apomorphine; Brain; Dihydroxyphenylalanine; Fusaric Acid; Isoproterenol; Norepi

1991
Dopaminergic facilitation of recovery from amygdaloid lesions which affect hypothalamic defensive attack in cats.
    Brain research, 1986, Jan-15, Volume: 363, Issue:1

    Topics: Aggression; Amygdala; Animals; Apomorphine; Brain Mapping; Cats; Dihydroxyphenylalanine; Dopamine; E

1986
A possible mechanism of action of a central stimulant substance isolated from the sea anemone Stoichactis kenti.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Adrenergic beta-Antagonists; Aggression; Amino Acids; Animals; Behavior, Animal; Chlorpromazine; Chr

1973
Influence of changes in brain monoamine metabolism on behaviour of herpes simplex-infected mice.
    Journal of the neurological sciences, 1974, Volume: 22, Issue:3

    Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dihydroxyphenylalanine; Diseas

1974
Effects of p-chlorophenylalanine, -methylparatyrosine and of other indol-and catechol-amine depletors on the hyperirritability syndrome of septal rats.
    Physiology & behavior, 1970, Volume: 5, Issue:5

    Topics: Aggression; Animals; Behavior, Animal; Brain; Brain Chemistry; Dihydroxyphenylalanine; Disulfiram; F

1970
Aggressive behaviour elicited in rats by Cannabis sativa: effects of p-chlorophenylalanine and DOPA.
    European journal of pharmacology, 1972, Volume: 17, Issue:2

    Topics: Aggression; Animals; Behavior, Animal; Cannabis; Dihydroxyphenylalanine; Drug Combinations; Drug Int

1972
Dopamine, noradrenaline and 5-hydroxy-trytamine in relation to motor activity, fighting and mounting behaviour. II. L-dopa and DL-threo-dihydroxyphenylserine in combination with Ro 4-4602 and parachlorophenylalanine.
    Neuropharmacology, 1973, Volume: 12, Issue:3

    Topics: Aggression; Animals; Benserazide; Brain; Catechols; Dihydroxyphenylalanine; Dopamine; Drug Interacti

1973
[Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)].
    Psychopharmacologia, 1974, Jan-11, Volume: 34, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Apomorphine; Biogenic Amines; Brain; Brain Chemistry; Clon

1974
An investigation on the behavioral and hypothermic effects of yohimbine: interaction with drugs affecting central and peripheral monoamines.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:1

    Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Bens

1974
Biogenic amines in normal and abnormal behavioral states.
    Clinical chemistry, 1971, Volume: 17, Issue:1

    Topics: Acetylcholine; Aggression; Aminobutyrates; Arousal; Blood-Brain Barrier; Brain; Brain Stem; Catechol

1971
Effects on shock-elicited aggression in mice of preferentially protecting brain monoamines against the depleting action of reserpine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Elec

1973
[Aggressiveness of the rat following combined treatment with monomaime oxidase inhibitors and other psychotropic drugs, especially thymoleptics].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1969, Volume: 264, Issue:1

    Topics: Aggression; Alkaloids; Amitriptyline; Amphetamine; Animals; Anthracenes; Body Temperature; Central N

1969
Aggression in rats treated with dopa and 6-hydroxydopamine.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:4

    Topics: Adrenal Glands; Aggression; Animals; Apomorphine; Dihydroxyphenylalanine; Humans; Hydrazines; Methyl

1972
Proceedings: Effects of L-DOPA, DDC and reserpine on monoamine consumption in brain mitochondria and aggressiveness of mice stressed by long-term isolation.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:0

    Topics: Aggression; Amines; Animals; Brain; Dicarboxylic Acids; Dihydroxyphenylalanine; Humans; Mice; Mitoch

1974
Clorazepate dipotassium, tranxene: anti-anxiety and antidepressant activity.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:1

    Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Benzazepines; Carboxylic Acids; Diazep

1973
6-Hydroxydopa depletion of brain norepinephrine and the function of aggressive behavior.
    Science (New York, N.Y.), 1972, Oct-06, Volume: 178, Issue:4056

    Topics: Aggression; Animals; Brain Chemistry; Brain Stem; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine;

1972
Dopamine, noradrenaline and 5-hydroxy-tryptamine in relation to motor activity, fighting and mounting behavior. I. L-dopa and DL-threo-dihydroxyphenylserine in combination with Ro 4-4602, pargyline and reserpine.
    Neuropharmacology, 1973, Volume: 12, Issue:3

    Topics: Aggression; Animals; Brain; Catechols; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Humans;

1973
The aggressive monoamines.
    Biological psychiatry, 1973, Volume: 6, Issue:2

    Topics: Aggression; Amines; Animals; Apomorphine; Appetitive Behavior; Behavior, Animal; Brain; Brain Chemis

1973
Effect of 6-hydroxydopamine pretreatment upon L-dopa-induced scatter jumping in mice.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Aggression; Animals; Blepharoptosis; Body Weight; Dihydroxyphenylalanine; Female; Humans; Hydroxydop

1973
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
    Psychopharmacologia, 1973, Volume: 32, Issue:2

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Me

1973
Apomorphine induced biting and fighting behaviour in reserpinized rats and an approach to the mechanism of action.
    Life sciences, 1974, Feb-16, Volume: 14, Issue:4

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Chlorpromazine; Clonid

1974
Shock-induced aggression: effects of 6-hydroxydopamine and other pharmacological agents.
    Brain research, 1972, Aug-25, Volume: 43, Issue:2

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Brain; Catecholamines; Desipramine; Dihydroxyphenylal

1972
Effects of some psychoactive drugs on conditioned avoidance response in aggressive mice.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 190, Issue:1

    Topics: Aggression; Animals; Antidepressive Agents; Avoidance Learning; Catecholamines; Conditioning, Psycho

1971
DOPA and other naturally occurring substances as causes of stereotypy and rage in rats.
    Acta psychiatrica Scandinavica. Supplementum, 1966, Volume: 191

    Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Behavior, Animal; Dihydroxyphenylalanine; Hum

1966
Aggression in mice associated with changes in the monoamine metabolism of the brain.
    Experientia, 1969, Sep-15, Volume: 25, Issue:9

    Topics: Aggression; Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Dopamine; Encephalitis; Fluoro

1969
Amphetamine-induced aggression in mice pretreated with dihydroxyphenylalanine (DOPA) and-or reserpine.
    Biological psychiatry, 1970, Volume: 2, Issue:3

    Topics: Aggression; Animals; Dextroamphetamine; Dihydroxyphenylalanine; Drug Synergism; Humans; Male; Mice;

1970
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds;

1970