dihydroxyphenylalanine has been researched along with Adult-Onset Dystonias in 13 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| " By dosage analysis, we were able to detect a mutation in all patients." | 1.36 | High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia. ( Chang, HC; Chen, RS; Huang, CC; Huang, CL; Lai, SC; Lin, JJ; Lu, CS; Wang, CY; Weng, YH; Wu-Chou, YH; Yeh, TH, 2010) |
| "strictly defined dopa-responsive dystonia." | 1.31 | Gene mutation in hereditary progressive dystonia with marked diurnal fluctuation (HPD), strictly defined dopa-responsive dystonia. ( Hagiwara, H; Kakimoto, S; Nishiyama, N; Nomura, Y; Segawa, M; Yukishita, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (69.23) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, C | 2 |
| Shi, W | 1 |
| Zeng, Z | 1 |
| Zhang, M | 1 |
| Ling, C | 1 |
| Chen, L | 1 |
| Zhang, B | 1 |
| Li, WD | 1 |
| Akiyama, T | 1 |
| Hayashi, Y | 1 |
| Hanaoka, Y | 1 |
| Shibata, T | 1 |
| Akiyama, M | 1 |
| Nakamura, K | 1 |
| Tsuyusaki, Y | 1 |
| Kubota, M | 1 |
| Yoshinaga, H | 1 |
| Kobayashi, K | 1 |
| Bobylova, MIu | 1 |
| Mikhaĭlova, SB | 1 |
| Grinio, LP | 1 |
| Wu-Chou, YH | 1 |
| Yeh, TH | 1 |
| Wang, CY | 1 |
| Lin, JJ | 1 |
| Huang, CC | 1 |
| Chang, HC | 1 |
| Lai, SC | 1 |
| Chen, RS | 1 |
| Weng, YH | 1 |
| Huang, CL | 1 |
| Lu, CS | 1 |
| Bertram, KL | 1 |
| Williams, DR | 1 |
| Furukawa, Y | 2 |
| Guttman, M | 1 |
| Wong, H | 1 |
| Farrell, SA | 1 |
| Furtado, S | 1 |
| Kish, SJ | 1 |
| Grötzsch, H | 1 |
| Schnorf, H | 1 |
| Morris, MA | 1 |
| Moix, I | 1 |
| Horvath, J | 1 |
| Prilipko, O | 1 |
| Burkhard, PR | 1 |
| Kang, JH | 1 |
| Kang, SY | 1 |
| Kang, HK | 1 |
| Koh, YS | 1 |
| Im, JH | 1 |
| Lee, MC | 1 |
| Casseron, W | 1 |
| Genton, P | 1 |
| Hui xie, H | 1 |
| Wu, ZY | 1 |
| Wang, N | 1 |
| Murong, SX | 1 |
| Asanuma, K | 1 |
| Carbon-Correll, M | 1 |
| Eidelberg, D | 1 |
| Nishiyama, N | 1 |
| Yukishita, S | 1 |
| Hagiwara, H | 1 |
| Kakimoto, S | 1 |
| Nomura, Y | 1 |
| Segawa, M | 1 |
2 reviews available for dihydroxyphenylalanine and Adult-Onset Dystonias
| Article | Year |
|---|---|
[DOPA-responsive dystonia (Segawa's disease)].
Topics: Dihydroxyphenylalanine; Dopamine Agents; Dystonic Disorders; Humans; Parkinson Disease; Substance-Re | 2009 |
Diagnosis of dystonic syndromes--a new eight-question approach.
Topics: Age of Onset; Brain; Dihydroxyphenylalanine; Dystonic Disorders; Hepatolenticular Degeneration; Huma | 2012 |
11 other studies available for dihydroxyphenylalanine and Adult-Onset Dystonias
| Article | Year |
|---|---|
GTP cyclohydrolase I and tyrosine hydroxylase gene mutations in familial and sporadic dopa-responsive dystonia patients.
Topics: Adult; Aged; Asian People; Dihydroxyphenylalanine; DNA Mutational Analysis; Dystonic Disorders; Exon | 2013 |
Simultaneous measurement of monoamine metabolites and 5-methyltetrahydrofolate in the cerebrospinal fluid of children.
Topics: Aromatic-L-Amino-Acid Decarboxylases; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; | 2017 |
High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia.
Topics: Adult; Asian People; Case-Control Studies; Cohort Studies; Dihydroxyphenylalanine; Dystonia; Dystoni | 2010 |
Genetics and biochemistry of dopa-responsive dystonia: significance of striatal tyrosine hydroxylase protein loss.
Topics: Animals; Biopterins; Dihydroxyphenylalanine; Dopamine; Dystonic Disorders; GTP Cyclohydrolase; Homov | 2003 |
Serum prolactin in symptomatic and asymptomatic dopa-responsive dystonia due to a GCH1 mutation.
Topics: Amino Acid Substitution; Dihydroxyphenylalanine; Dystonic Disorders; Exons; Female; Genes, Dominant; | 2003 |
Phenotypic heterogeneity of dopa-responsive dystonia in monozygotic twins.
Topics: Adult; Benserazide; Biopterins; Clubfoot; Dihydroxyphenylalanine; Disease Progression; Diseases in T | 2004 |
A novel missense mutation of the GTP cyclohydrolase I gene in a Korean family with hereditary progressive dystonia/dopa-responsive dystonia.
Topics: Adolescent; Child; Child, Preschool; Dihydroxyphenylalanine; DNA Mutational Analysis; Dopamine Agent | 2004 |
DOPA-sensitive dystonia-plus syndrome.
Topics: Adolescent; Benserazide; Brain; Child; Child Behavior Disorders; Child, Preschool; Craniofacial Abno | 2005 |
Gene symbol: GTP cyclohydrolase I (GCH-I). Disease: dopa-responsive dystonia.
Topics: Amino Acid Substitution; Dihydroxyphenylalanine; Dystonic Disorders; GTP Cyclohydrolase; Humans; Mut | 2005 |
Neuroimaging in human dystonia.
Topics: Anisotropy; Basal Ganglia; Blepharospasm; Carbon Radioisotopes; Case-Control Studies; Dihydroxypheny | 2005 |
Gene mutation in hereditary progressive dystonia with marked diurnal fluctuation (HPD), strictly defined dopa-responsive dystonia.
Topics: Dihydroxyphenylalanine; DNA Mutational Analysis; Dystonia; Dystonic Disorders; Exons; Female; GTP Cy | 2000 |