Page last updated: 2024-10-18

dihydroxyphenylalanine and Adenoma, Islet Cell

dihydroxyphenylalanine has been researched along with Adenoma, Islet Cell in 6 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Adenoma, Islet Cell: A benign tumor of the pancreatic ISLET CELLS. Usually it involves the INSULIN-producing PANCREATIC BETA CELLS, as in INSULINOMA, resulting in HYPERINSULINISM.

Research Excerpts

ExcerptRelevanceReference
"In recent years, 6-l-18F-fluorodihydroxyphenylalanine (18F-DOPA) PET has emerged as a new diagnostic tool for the imaging of neuroendocrine tumors."8.846-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications. ( Brouwers, AH; Chirakal, R; Gulenchyn, KY; Jager, PL; Koopmans, KP; Marriott, CJ, 2008)
"In recent years, 6-l-18F-fluorodihydroxyphenylalanine (18F-DOPA) PET has emerged as a new diagnostic tool for the imaging of neuroendocrine tumors."4.846-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications. ( Brouwers, AH; Chirakal, R; Gulenchyn, KY; Jager, PL; Koopmans, KP; Marriott, CJ, 2008)
"In all carcinoid patients (18)F-DOPA PET and (11)C-5-HTP PET detected more lesions than SRS (P < ."1.35Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography. ( Brouwers, AH; de Vries, EG; Elsinga, PH; Jager, PL; Kema, IP; Koopmans, KP; Neels, OC; Sluiter, WJ; Vanghillewe, K, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Mitrofanova, LB1
Perminova, AA1
Ryzhkova, DV1
Sukhotskaya, AA1
Bairov, VG1
Nikitina, IL1
Jager, PL2
Chirakal, R1
Marriott, CJ1
Brouwers, AH2
Koopmans, KP2
Gulenchyn, KY1
Neels, OC1
Kema, IP1
Elsinga, PH1
Sluiter, WJ1
Vanghillewe, K1
de Vries, EG1
Cegrell, L2
Falck, B1
Rosengren, AM2
Axelsson, S1
Käser, H1
Wagner, HP1
Zuppinger, K1
Zurbrügg, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Fluorodopa F 18 Positron Emission Tomography Combined With Computed Tomography in Congenital Hyperinsulinism and Insulinoma[NCT02021604]Phase 1250 participants (Anticipated)Interventional2013-10-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dihydroxyphenylalanine and Adenoma, Islet Cell

ArticleYear
6-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:4

    Topics: Adenoma, Islet Cell; Dihydroxyphenylalanine; Humans; Hyperinsulinism; Neuroendocrine Tumors; Pancrea

2008

Other Studies

5 other studies available for dihydroxyphenylalanine and Adenoma, Islet Cell

ArticleYear
Differential Morphological Diagnosis of Various Forms of Congenital Hyperinsulinism in Children.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adenoma; Adenoma, Islet Cell; Congenital Hyperinsulinism; Diagnosis, Differential; Dihydroxyphenylal

2021
Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Mar-20, Volume: 26, Issue:9

    Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Adult; Aged; Carbon Radioisotopes; Carcinoid Tumor; Dihydr

2008
Dopa-decarboxylase and monoamine oxidase activities in a transplantable islet cell tumor of the golden hamster.
    Experientia, 1969, Sep-15, Volume: 25, Issue:9

    Topics: Adenoma, Islet Cell; Animals; Cricetinae; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Hist

1969
Tyrosine hydroxylase activity in a transplantable islet cell tumour of golden hamster.
    Experientia, 1970, Sep-26, Volume: 26, Issue:9

    Topics: Adenoma, Islet Cell; Amides; Animals; Cricetinae; Dihydroxyphenylalanine; Female; Folic Acid; Hydraz

1970
[Biochemical tumor diagnosis in childhood].
    Schweizerische medizinische Wochenschrift, 1974, May-04, Volume: 104, Issue:18

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Carcinoma, Hepatocellular; Child; Cushing Syndrome; De

1974