dihydroxyphenylalanine has been researched along with ANS (Autonomic Nervous System) Diseases in 9 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pure autonomic failure (PAF) and Parkinson's disease (PD) share several clinical laboratory abnormalities; however, PAF is not associated with parkinsonism." | 1.35 | Central dopamine deficiency in pure autonomic failure. ( Bernson, M; Carmona, G; Goldstein, DS; Holmes, C; Imrich, R; Mizrahi, N; Sato, T; Sharabi, Y; Vortmeyer, AO, 2008) |
| "Ten patients with sporadic olivopontocerebellar atrophy and autonomic failure were studied with positron emission tomography." | 1.29 | Positron emission tomography studies on the dopaminergic system and striatal opioid binding in the olivopontocerebellar atrophy variant of multiple system atrophy. ( Brooks, DJ; Burn, DJ; Marsden, CD; Mathias, CJ; Quinn, NP; Rinne, JO, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldstein, DS | 4 |
| Holmes, C | 3 |
| Frank, SM | 1 |
| Dendi, R | 1 |
| Cannon, RO | 1 |
| Sharabi, Y | 2 |
| Esler, MD | 1 |
| Eisenhofer, G | 1 |
| McGorum, BC | 1 |
| Wilson, R | 1 |
| Pirie, RS | 1 |
| Mayhew, IG | 1 |
| Kaur, H | 1 |
| Aruoma, OI | 1 |
| Imrich, R | 2 |
| Peckham, E | 1 |
| Lopez, G | 1 |
| Crews, C | 1 |
| Hardy, J | 1 |
| Singleton, A | 1 |
| Hallett, M | 1 |
| Sato, T | 1 |
| Bernson, M | 1 |
| Mizrahi, N | 1 |
| Carmona, G | 1 |
| Vortmeyer, AO | 1 |
| Rinne, JO | 1 |
| Burn, DJ | 1 |
| Mathias, CJ | 2 |
| Quinn, NP | 1 |
| Marsden, CD | 2 |
| Brooks, DJ | 2 |
| Yamamoto, T | 1 |
| Polinsky, RJ | 1 |
| Baucom, CE | 1 |
| Kopin, IJ | 1 |
| Kaufmann, H | 1 |
| Jankovic, J | 1 |
| Kapadia, AS | 1 |
| Salmon, EP | 1 |
| Quinn, N | 1 |
| Leenders, KL | 1 |
| Bannister, R | 1 |
| Frackowiak, RS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Laboratory Evaluation of Chronic Orthostatic Intolerance[NCT00069693] | 200 participants | Observational | 2003-09-26 | Completed | |||
| Propranolol for Syncope With Sympathoadrenal Imbalance[NCT00060866] | Phase 4 | 24 participants | Interventional | 2003-05-31 | Completed | ||
| Propranolol for Syncope With Sympathoadrenal Imbalance in Children[NCT00093860] | Phase 2 | 50 participants | Interventional | 2004-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dihydroxyphenylalanine and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
8 other studies available for dihydroxyphenylalanine and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Systemic concentrations of antioxidants and biomarkers of macromolecular oxidative damage in horses with grass sickness.
Topics: Animals; Antioxidants; Autonomic Nervous System Diseases; Biomarkers; Case-Control Studies; Chromato | 2003 |
Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation.
Topics: Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Baroreflex; Dihydroxyphenylalanine; DNA Mut | 2007 |
Central dopamine deficiency in pure autonomic failure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Autonomic Nervous System Diseases; Brain; Catechols; Dihydroxy | 2008 |
Positron emission tomography studies on the dopaminergic system and striatal opioid binding in the olivopontocerebellar atrophy variant of multiple system atrophy.
Topics: Autonomic Nervous System Diseases; Carbon Radioisotopes; Corpus Striatum; Dihydroxyphenylalanine; Di | 1995 |
Plasma sulfoconjugated dopamine levels are normal in patients with autonomic failure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Autonomic Nervous System Diseases; Case-Control Studies; Dihydroxyph | 1996 |
Could treatment with DOPS do for autonomic failure what DOPA did for Parkinson's disease?
Topics: Autonomic Nervous System Diseases; Dihydroxyphenylalanine; Droxidopa; Humans; Parkinson Disease | 1996 |
Functional decline in Parkinson disease.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Demogra | 2001 |
The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET.
Topics: Adult; Aged; Atrophy; Autonomic Nervous System; Autonomic Nervous System Diseases; Brain Diseases; C | 1990 |