Compounds > dihydrotetrabenazine
Page last updated: 2024-09-03

dihydrotetrabenazine and Parkinson Disease

dihydrotetrabenazine has been researched along with Parkinson Disease in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.27)18.7374
1990's5 (11.36)18.2507
2000's15 (34.09)29.6817
2010's22 (50.00)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Bohnen, NI; D'Cruz, N; Kanel, P; Müller, MLTM; Sanchez-Catasus, CA; Yeh, FC1
Bohnen, JLB; Bohnen, NI; Haugen, J; Müller, MLTM1
Gjedde, A; Jakobsen, S; Landau, AM; Phan, JA; Romero-Ramos, M; Stokholm, K; Vang, K; Zareba-Paslawska, J1
Barrett, MJ; Bassett, AS; Berman, BD; Booij, J; Boot, E; Borg, M; Bourdain, F; Butcher, NJ; Charles, P; Clerinx, K; Colin, O; Danaila, T; Drapier, S; Dufournet, B; Fiksinski, AM; Gasser, T; Jacquette, A; Kaneko, S; Lang, AE; Marras, C; Masellis, M; Mills, K; Mok, KY; Mutez, E; Nguyen, K; Perandones, C; Plate, A; Prontera, P; Swillen, A; Udow, S; Vergaelen, E; Vogels, A; Williams, NM; Wood, NW1
Hsiao, IT; Jung Lung, H; Lin, KJ; Wen, MC; Weng, YH1
Cervantes-Arriaga, A; Díaz-Meneses, IE; Kerik, NE; Pérez-Lohman, C; Rodríguez-Violante, M1
Albin, RL; Archer, DB; Bohnen, NI; Burciu, RG; Müller, MLTM; Ofori, E; Roy, A; Vaillancourt, DE; Yang, J1
Bohnen, NI; Dayalu, P; Kwak, Y; Miller, NS; Müller, ML; Seidler, RD1
Albin, RL; Bohnen, NI; Frey, KA; Koeppe, RA; Kotagal, V; Müller, ML; Scott, PJ; Studenski, S1
Albin, RL; Bohnen, NI; Frey, KA; Koeppe, RA; Kotagal, V; Müller, ML1
Hsiao, IT; Hsieh, CJ; Kung, MP; Lin, KJ; Lin, WY; Lu, CS; Weng, YH; Wey, SP; Yen, TC1
Albin, RL; Bohnen, NI; Constantine, GM; Frey, KA; Koeppe, RA; Kotagal, V; Müller, ML; Scott, PJ; Studenski, S1
Blesa, J; Cavada, C; Hornykiewicz, O; Obeso, JA; Pifl, C; Rajput, A; Rajput, AH; Reither, H1
Bohnen, NI; Chou, KL; Koeppe, RA; Lenhart, A1
Albin, RL; Bohnen, NI; Frey, KA; Koeppe, RA; Kotagal, V; Müller, ML; Petrou, M; Scott, PJ1
Collantes, M; Delgado, M; Ecay, M; Gago, B; Iglesias, E; Juri, C; Marín, C; Molinet-Dronda, F; Obeso, JA; Peñuelas, I; Prieto, E; Quiroga-Varela, A1
Albin, RL; Bohnen, NI; Frey, KA; Koeppe, RA; Kotagal, V; Müller, ML; Petrou, M; Scott, PJ; Shah, N1
Albin, RL; Bohnen, NI; Davatzikos, C; Foerster, BR; Frey, KA; Herman, WH; Hsieh, M; Koeppe, RA; Kotagal, V; Müller, ML; Petrou, M1
Frey, KA; Gilman, S; Junck, L; Koeppe, RA; Wernette, K1
Boileau, I; Guttman, M; Houle, S; Kish, SJ; Rusjan, P; Saint-Cyr, JA; Selby, P; Tong, J; Wilkins, D; Wilson, AA1
de la Fuente-Fernandez, R; Mak, E; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ; Troiano, AR1
Vingerhoets, FJ1
de la Fuente-Fernández, R; McCormick, S; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ1
Au, WL; Calne, DB; Cragg, J; de la Fuente-Fernández, R; Kuramoto, L; Lee, CS; Mak, E; McCormick, S; McKenzie, J; Ramachandiran, N; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ1
Albin, RL; Bogan, CW; Bohnen, NI; Frey, KA; Kilbourn, MR; Koeppe, RA; Müller, ML; Zarzhevsky, N1
Aasly, JO; Armaly, J; Furay, AR; Hasegawa, K; Leverenz, JB; Shi, M; Sossi, V; Stoessl, AJ; Uitti, RJ; Wang, Y; Wszolek, ZK; Yokoyama, T; Zabetian, CP; Zhang, J1
Albin, RL; Bohnen, NI; Frey, KA; Gilman, S; Kilbourn, MR; Koeppe, RA; Kotagal, V; Müller, ML1
Albin, RL; Bohnen, NI; Frey, KA; Koeppe, RA; Kotagal, V; Müller, ML; Petrou, M1
Calne, DB; De La Fuente-Fernández, R; Furtado, S; Furukawa, Y; Guttman, M; Lee, CS; Ruth, TJ; Stoessl, AJ1
Kumar, A; Lee, CS; Mann, S; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ1
Brooks, DJ; Frey, KA; Marek, KL; Oakes, D; Paty, D; Prentice, R; Shults, CW; Stoessl, AJ1
Calne, DB; de la Fuente-Fernández, R; Kuramoto, L; Lee, CS; Mak, E; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ1
Ahlskog, JE; Albin, RL; Brooks, DJ; Carbon, M; Dhawan, V; Eidelberg, D; Fahn, S; Feigin, A; Guttman, M; Gwinn-Hardy, K; Holloway, R; Innis, R; Katz, RG; Kieburtz, K; Kish, SJ; Lange, N; Langston, JW; Marek, K; McFarland, H; Morin, L; Moy, C; Murphy, D; Oertel, WH; Oliver, G; Palesch, Y; Powers, W; Ravina, B; Seibyl, J; Sethi, KD; Sheehy, P; Shults, CW; Stoessl, AJ1
Adams, JR; Calne, DB; Farrer, M; Gasser, T; Lee, CS; Mak, E; Mckenzie, J; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ; Strongosky, A; Uitti, RJ; van Netten, H; Wszolek, ZK1
Albin, RL; Bohnen, NI; Frey, KA; Kilbourn, MR; Koeppe, RA; Minoshima, S; Wernette, KA1
Martin, WR; Schulzer, M; Stoessl, AJ; Wieler, M1
Agid, Y; Anglade, P; Brandel, JP; Duyckaerts, C; Hirsch, EC; Javoy-Agid, F; Lehéricy, S; Scherman, D; Villares, J1
Agid, Y; Javoy-Agid, F; Ruberg, M; Scherman, D1
Albin, RL; Frey, KA; Gilman, S; Kilbourn, MR; Koeppe, RA; Kuhl, DE; Vander Borght, TM1
Frey, KA; Kilbourn, MR; Wieland, DM1
Agid, Y; Duyckaerts, C; Faucheux, B; Hauw, JJ; Herrero, MT; Hirsch, EC; Obeso, JA; Villares, J1
Calne, DB; de la Fuente-Fernandez, R; Holden, JE; Lee, CS; Pal, PK; Ruth, TJ; Samii, A; Schulzer, M; Sossi, V; Stoessl, AJ; Wudel, J1
Stoessl, AJ1
Agid, Y; Blin, J; Desnos, C; Javoy-Agid, F; Pierot, L; Raisman, R; Ruberg, M; Scherman, D1

Reviews

3 review(s) available for dihydrotetrabenazine and Parkinson Disease

ArticleYear
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease.
    Experimental neurology, 2003, Volume: 184 Suppl 1

    Topics: Animals; Basal Ganglia; Biomarkers; Cocaine; Diagnostic Imaging; Dihydroxyphenylalanine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease; Radiopharmaceuticals; Technology Assessment, Biomedical; Tetrabenazine; Tomography, Emission-Computed, Single-Photon; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2003
The role of radiotracer imaging in Parkinson disease.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Biomarkers; Biotransformation; Blood-Brain Barrier; Carbon Radioisotopes; Clinical Trials as Topic; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Forecasting; Humans; Iodine Radioisotopes; Neurons; Parkinson Disease; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Receptors, Dopamine; Substantia Nigra; Tetrabenazine; Tomography, Emission-Computed, Single-Photon

2005
Assessing the integrity of the dopamine system in Parkinson's disease: how best to do it?
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:5

    Topics: Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Neural Pathways; Parkinson Disease; Severity of Illness Index; Substantia Nigra; Tetrabenazine; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

2001

Other Studies

41 other study(ies) available for dihydrotetrabenazine and Parkinson Disease

ArticleYear
Dopaminergic Nigrostriatal Connectivity in Early Parkinson Disease: In Vivo Neuroimaging Study of
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021, Volume: 62, Issue:4

    Topics: Carbon Radioisotopes; Diffusion Tensor Imaging; Dopamine; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Neostriatum; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine

2021
Mentally stimulating activities associate with better cognitive performance in Parkinson disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2017, Volume: 124, Issue:10

    Topics: Aged; Aged, 80 and over; Carbon Isotopes; Cognition Disorders; Cognitive Behavioral Therapy; Female; Humans; Magnetic Resonance Imaging; Male; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Parkinson Disease; Phosphinic Acids; Piperidines; Positron-Emission Tomography; Regression Analysis; Tetrabenazine

2017
Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease.
    Scientific reports, 2017, 07-25, Volume: 7, Issue:1

    Topics: alpha-Synuclein; Animals; Carbon Radioisotopes; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Humans; Parkinson Disease; Positron-Emission Tomography; Presynaptic Terminals; Rats; Rats, Transgenic; Substantia Nigra; Synapses; Tetrabenazine; Vesicular Monoamine Transport Proteins

2017
Typical features of Parkinson disease and diagnostic challenges with microdeletion 22q11.2.
    Neurology, 2018, 06-05, Volume: 90, Issue:23

    Topics: Adult; Antiparkinson Agents; Databases, Bibliographic; Deep Brain Stimulation; DiGeorge Syndrome; Female; Humans; International Cooperation; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Sex Distribution; Statistics, Nonparametric; Tetrabenazine; Tomography, Emission-Computed, Single-Photon

2018
Quantitative study of
    Scientific reports, 2018, 10-30, Volume: 8, Issue:1

    Topics: Aged; Brain; Case-Control Studies; Female; Fluorine Radioisotopes; Functional Neuroimaging; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Tetrabenazine

2018
Diagnostic Utility of [11C]DTBZ Positron Emission Tomography In Clinically Uncertain Parkinsonism: Experience of a Single Tertiary Center.
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 2018, Volume: 70, Issue:6

    Topics: Adult; Aged; Brain; Carbon Radioisotopes; Female; Humans; Male; Mexico; Middle Aged; Parkinson Disease; Parkinsonian Disorders; Predictive Value of Tests; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tetrabenazine; Tomography, Emission-Computed, Single-Photon

2018
Multimodal dopaminergic and free-water imaging in Parkinson's disease.
    Parkinsonism & related disorders, 2019, Volume: 62

    Topics: Adult; Aged; Aged, 80 and over; Brain; Dopamine; Female; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine; Tremor; Water

2019
The pattern of striatal dopaminergic denervation explains sensorimotor synchronization accuracy in Parkinson's disease.
    Behavioural brain research, 2013, Nov-15, Volume: 257

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbon Isotopes; Cluster Analysis; Corpus Striatum; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Motor Activity; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Tetrabenazine; Time Factors; Time Perception

2013
Gait speed in Parkinson disease correlates with cholinergic degeneration.
    Neurology, 2013, Oct-29, Volume: 81, Issue:18

    Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Analysis of Variance; Carbon Isotopes; Cerebral Cortex; Cognition Disorders; Cross-Sectional Studies; Dioxolanes; Female; Gait Disorders, Neurologic; Humans; Male; Middle Aged; Nerve Degeneration; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine; Vesicular Monoamine Transport Proteins

2013
Modifiable cardiovascular risk factors and axial motor impairments in Parkinson disease.
    Neurology, 2014, Apr-29, Volume: 82, Issue:17

    Topics: Aged; Body Mass Index; Carbon Radioisotopes; Cardiovascular Diseases; Cross-Sectional Studies; Disability Evaluation; Female; Humans; Imaging, Three-Dimensional; Leukoaraiosis; Male; Middle Aged; Movement; Neuropsychological Tests; Parkinson Disease; Radionuclide Imaging; Reference Values; Rhombencephalon; Risk Factors; Severity of Illness Index; Tetrabenazine

2014
Correlation of Parkinson disease severity and 18F-DTBZ positron emission tomography.
    JAMA neurology, 2014, Volume: 71, Issue:6

    Topics: Adult; Aged; Female; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine; Tremor

2014
Extra-nigral pathological conditions are common in Parkinson's disease with freezing of gait: an in vivo positron emission tomography study.
    Movement disorders : official journal of the Movement Disorder Society, 2014, Volume: 29, Issue:9

    Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Carbon Isotopes; Cross-Sectional Studies; Female; Freezing Reaction, Cataleptic; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Substantia Nigra; Tetrabenazine; Thiazoles; Vesicular Monoamine Transport Proteins

2014
Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Jun-11, Volume: 34, Issue:24

    Topics: Aged; Aged, 80 and over; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; Homovanillic Acid; Humans; Macaca fascicularis; Male; MPTP Poisoning; Parkinson Disease; Synaptic Vesicles; Tetrabenazine; Tritium; Vesicular Monoamine Transport Proteins

2014
Abnormal MoCA and normal range MMSE scores in Parkinson disease without dementia: cognitive and neurochemical correlates.
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:10

    Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Brain; Cognition Disorders; Female; Guanidines; Humans; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine; Vesicular Monoamine Transport Proteins

2014
Diabetes mellitus is independently associated with more severe cognitive impairment in Parkinson disease.
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:12

    Topics: Aged; Butyrates; Carbon Isotopes; Cognition Disorders; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Neuroimaging; Neuropsychological Tests; Parkinson Disease; Piperidines; Positron-Emission Tomography; Severity of Illness Index; Tetrabenazine

2014
Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: a longitudinal in-vivo study.
    Neurobiology of disease, 2015, Volume: 77

    Topics: Adrenergic Agents; Animals; Apomorphine; Brain; Carbon Radioisotopes; Disease Models, Animal; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Functional Laterality; Longitudinal Studies; Magnetic Resonance Imaging; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrabenazine

2015
Striatal and Cortical β-Amyloidopathy and Cognition in Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Analysis of Variance; Aniline Compounds; Carbon Isotopes; Cerebral Cortex; Cognition Disorders; Corpus Striatum; Cross-Sectional Studies; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine; Thiazoles

2016
Diabetes, Gray Matter Loss, and Cognition in the Setting of Parkinson Disease.
    Academic radiology, 2016, Volume: 23, Issue:5

    Topics: Aged; Atrophy; Attention; Basal Ganglia; Brain Diseases; Carbon Radioisotopes; Case-Control Studies; Cognition; Cross-Sectional Studies; Diabetes Complications; Dopaminergic Neurons; Executive Function; Female; Frontal Lobe; Gray Matter; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Tetrabenazine

2016
Differentiating Alzheimer's disease from dementia with Lewy bodies and Parkinson's disease with (+)-[11C]dihydrotetrabenazine positron emission tomography.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2008, Volume: 4, Issue:1 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Diagnosis, Differential; Female; Humans; Lewy Body Disease; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Tetrabenazine

2008
Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker?
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-24, Volume: 28, Issue:39

    Topics: Adult; Analysis of Variance; Brain Mapping; Central Nervous System Stimulants; Corpus Striatum; Female; Humans; Magnetic Resonance Imaging; Male; Methamphetamine; Middle Aged; Neurologic Examination; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Substance Withdrawal Syndrome; Tetrabenazine; Time Factors; Vesicular Monoamine Transport Proteins

2008
PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.
    Neurology, 2009, Apr-07, Volume: 72, Issue:14

    Topics: Caudate Nucleus; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Female; Humans; Logistic Models; Male; Methylphenidate; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Radiopharmaceuticals; Tetrabenazine

2009
Dyskinesia in Parkinson disease: back for the future?
    Neurology, 2009, Apr-07, Volume: 72, Issue:14

    Topics: Antiparkinson Agents; Dopamine Agents; Dyskinesias; Humans; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Synapses; Tetrabenazine

2009
Visualizing vesicular dopamine dynamics in Parkinson's disease.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:8

    Topics: Antiparkinson Agents; Brain Mapping; Carbon Radioisotopes; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Nonlinear Dynamics; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine

2009
Age-specific progression of nigrostriatal dysfunction in Parkinson's disease.
    Annals of neurology, 2011, Volume: 69, Issue:5

    Topics: Adult; Aged; Aging; Carbon Isotopes; Corpus Striatum; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Longitudinal Studies; Male; Methylphenidate; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Substantia Nigra; Tetrabenazine; Tritium; Young Adult

2011
Leucoaraiosis, nigrostriatal denervation and motor symptoms in Parkinson's disease.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 8

    Topics: Aged; Aged, 80 and over; Carbon Isotopes; Corpus Striatum; Denervation; Female; Humans; Leukoaraiosis; Male; Middle Aged; Motor Activity; Parkinson Disease; Positron-Emission Tomography; Regression Analysis; Substantia Nigra; Tetrabenazine; Vesicular Monoamine Transport Proteins

2011
DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function.
    Neurobiology of aging, 2012, Volume: 33, Issue:4

    Topics: alpha-Synuclein; Biomarkers; Carbon Isotopes; Corpus Striatum; Dopamine; Female; Fluorodeoxyglucose F18; Humans; Intracellular Signaling Peptides and Proteins; Japan; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Luria-Nebraska Neuropsychological Battery; Male; Methylphenidate; Norway; Oncogene Proteins; Parkinson Disease; Positron-Emission Tomography; Protein Deglycase DJ-1; Protein Serine-Threonine Kinases; Statistics as Topic; Tetrabenazine; United States

2012
Heterogeneity of cholinergic denervation in Parkinson's disease without dementia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:8

    Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Carbon Radioisotopes; Cognition; Corpus Striatum; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Motor Activity; Neocortex; Parkinson Disease; Positron-Emission Tomography; Propionates; Tetrabenazine; Thalamus

2012
β-Amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementia.
    Movement disorders : official journal of the Movement Disorder Society, 2013, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Carbon Isotopes; Cross-Sectional Studies; Dementia; Female; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Postural Balance; Psychiatric Status Rating Scales; Sensation Disorders; Severity of Illness Index; Tetrabenazine; Thiazoles

2013
VMAT2 binding is elevated in dopa-responsive dystonia: visualizing empty vesicles by PET.
    Synapse (New York, N.Y.), 2003, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Carbon Radioisotopes; Corpus Striatum; Cytoplasmic Vesicles; Dopamine; Dopamine Agents; Dystonic Disorders; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Middle Aged; Neuropeptides; Parkinson Disease; Raclopride; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2003
[11C]DTBZ-PET correlates of levodopa responses in asymmetric Parkinson's disease.
    Brain : a journal of neurology, 2003, Volume: 126, Issue:Pt 12

    Topics: Aged; Antiparkinson Agents; Dopamine; Fingers; Humans; Image Processing, Computer-Assisted; Levodopa; Middle Aged; Movement; Parkinson Disease; Reaction Time; Synaptic Vesicles; Tetrabenazine; Tomography, Emission-Computed

2003
Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis.
    Archives of neurology, 2004, Volume: 61, Issue:12

    Topics: Aged; Brain; Disease Progression; Dopamine; Female; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Regression Analysis; Tetrabenazine

2004
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 12

    Topics: Adult; Age Factors; Aged; Brain; Carbon Radioisotopes; Carboxy-Lyases; Case-Control Studies; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Methylphenidate; Middle Aged; Mutation; Parkinson Disease; Phenotype; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Radiopharmaceuticals; Receptors, Dopamine D2; Regression Analysis; Tetrabenazine

2005
Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aging; Algorithms; Biogenic Monoamines; Female; Humans; Male; Middle Aged; Neostriatum; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Synaptic Vesicles; Tetrabenazine; Vesicular Monoamine Transport Proteins

2006
Dihydrotetrabenazine positron emission tomography imaging in early, untreated Parkinson's disease.
    Annals of neurology, 2008, Volume: 63, Issue:3

    Topics: Adult; Aged; Corpus Striatum; Cross-Sectional Studies; Early Diagnosis; Female; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Tetrabenazine

2008
Monoamine vesicular uptake sites in patients with Parkinson's disease and Alzheimer's disease, as measured by tritiated dihydrotetrabenazine autoradiography.
    Brain research, 1994, Oct-03, Volume: 659, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Binding Sites; Biogenic Monoamines; Corpus Striatum; Female; Humans; Male; Middle Aged; Parkinson Disease; Reference Values; Tetrabenazine; Tritium

1994
Dopamine denervation, age of onset, and Parkinson's disease.
    Neurology, 1995, Volume: 45, Issue:2

    Topics: Age of Onset; Aged; Caudate Nucleus; Denervation; Dopamine; Humans; Middle Aged; Parkinson Disease; Tetrabenazine; Tritium

1995
Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging.
    Annals of neurology, 1996, Volume: 40, Issue:6

    Topics: Adult; Aged; Aging; Animals; Biological Transport; Biomarkers; Blood-Brain Barrier; Cerebral Cortex; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neuropeptides; Parkinson Disease; Presynaptic Terminals; Rats; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

1996
Imaging of monoaminergic and cholinergic vesicular transporters in the brain.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Acetylcholine; Alzheimer Disease; Brain; Carbon Radioisotopes; Carrier Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Neuromuscular Depolarizing Agents; Neurons; Neuropeptides; Neurotransmitter Agents; Parkinson Disease; Piperidines; Tetrabenazine; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Tritium; Vesicular Acetylcholine Transport Proteins; Vesicular Biogenic Amine Transport Proteins; Vesicular Transport Proteins

1998
[125I]EGF binding in basal ganglia of patients with Parkinson's disease and progressive supranuclear palsy and in MPTP-treated monkeys.
    Experimental neurology, 1998, Volume: 154, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Aged, 80 and over; Animals; Basal Ganglia; Brain Diseases; Dopamine Agents; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Immunohistochemistry; Iodine Radioisotopes; Macaca fascicularis; Male; Parkinson Disease; Supranuclear Palsy, Progressive; Tetrabenazine

1998
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease.
    Annals of neurology, 2000, Volume: 47, Issue:4

    Topics: Aged; Carbon Radioisotopes; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Fluorine Radioisotopes; Homovanillic Acid; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Presynaptic Terminals; Tetrabenazine; Tomography, Emission-Computed

2000
D1 and D2-type dopamine receptors in patients with Parkinson's disease and progressive supranuclear palsy.
    Journal of the neurological sciences, 1988, Volume: 86, Issue:2-3

    Topics: Adenylyl Cyclases; Adult; Aged; Benzazepines; Caudate Nucleus; Dopamine Antagonists; Humans; Middle Aged; Parkinson Disease; Putamen; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Spiperone; Supranuclear Palsy, Progressive; Tetrabenazine

1988