Page last updated: 2024-08-21

dihydrotestosterone and Polycystic Ovarian Syndrome

dihydrotestosterone has been researched along with Polycystic Ovarian Syndrome in 139 studies

Research

Studies (139)

TimeframeStudies, this research(%)All Research%
pre-199023 (16.55)18.7374
1990's5 (3.60)18.2507
2000's13 (9.35)29.6817
2010's62 (44.60)24.3611
2020's36 (25.90)2.80

Authors

AuthorsStudies
Billig, H; Brännström, M; Hu, M; Li, J; Liang, M; Ma, H; Ma, S; Sferruzzi-Perri, AN; Shao, LR; Wang, X; Wu, X; Zhang, Y1
Cui, P; Feng, Y; Hu, W; Li, X; Liu, Y; Lu, W; Ma, T; Pei, Z; Shi, J; Tong, X; Xu, C; Xu, M; Xu, X; Zhang, F1
Campbell, RE; Coyle, CS; Handelsman, DJ; Prescott, M; Walters, KA1
Mesaros, CA; Paulukinas, RD; Penning, TM1
Cochran, BJ; Edwards, MC; Gilchrist, RB; Handelsman, DJ; Hu, Y; Ledger, WL; Padmanabhan, V; Rodriguez Paris, V; Rye, KA; Walters, KA; Xiong, T1
Divall, S; Feng, M; Fu, X; Jones, D; Ubba, V; Wang, H; Wu, S; Yang, L; Yang, X1
Aflatounian, A; Bertoldo, MJ; Cochran, BJ; Edwards, MC; Gilchrist, RB; Ledger, WL; Paris, VR; Richani, D; Walters, KA; Wu, LE1
Anesetti, G; Chávez-Genaro, R; Hernández, K; Toledo, A1
Brown, RSE; Campbell, RE; Desroziers, E; Khant Aung, Z; Masih, RR1
Banks, DB; Binder, AK; Gutierrez, SD; Korach, KS; Magaña, J; Peecher, DL; Qvigstad, AJ1
Guo, Z; Liu, D; Lv, L; Ma, H; Radovic, C1
Baker, M; Dancz, CE; Legro, RS; Ma, L; Mandelbaum, R; Sriprasert, I; Stanczyk, FZ1
Djordjevic, A; Ignjatović, Đ; Macut, D; Mićić, B; Tomić, M; Tovilović-Kovačević, G; Vojnović Milutinović, D1
Anderson, GM; Inglis, MA; Kerbus, RI1
Jahangiri, S; Librach, CL; Osuga, Y; Salehi, R; Tsang, B; Tzeng, CR; Urata, Y; Wyse, BA1
Billig, H; Brännström, M; Hu, M; Huang, X; Li, Y; Lu, Y; Sferruzzi-Perri, AN; Shao, LR; Zhang, X; Zhang, Y1
He, JJ; Jing, YX; Li, HX; Li, YM; Yu, X; Yue, F; Zhang, XH1
Hsia, SM; Lin, PH; Wang, KL; Wang, PS1
Fiocco, A; Isidoro, C; Lima, P; Mazier, HL; Nivet, AL; Reunov, AA; Salehi, R; Tsang, BK; Wang, Q1
Gopalakrishnan, V; Krishnan, A; Muthusami, S; Periyasamy, L; Ramachandran, I; Stanley, JA1
Li, S; Li, Y; Liang, C; Wen, X; Yu, J; Zheng, Y1
Bar-Joseph, H; Ben-Ami, I; Miller, I; Nemerovsky, L; Shalgi, R1
Aflatounian, A; Cox, MJ; Edwards, MC; Gilchrist, RB; Handelsman, DJ; Ledger, WL; Padmanabhan, V; Rodriguez Paris, V; Walters, KA1
Choi, DH; Kim, HR; Kim, YS; Lee, BS; Lee, MH; Lyu, SW; Song, H; Yoon, JA1
Baixeras, E; de Fonseca, FR; Gutierrez-Adan, A; Gutierrez-Arroyo, JL; Laguna-Barraza, R; Navarro, JA; Pericuesta, E; Ramos-Ibeas, P; Sanjuan, C; Vera, K1
Fu, P; Gao, Z; Ge, Y; Liu, J; Liu, Z; Ma, X; Wang, L; Yan, X; Yao, R1
Chen, Y; Cui, T; Li, T; Liu, R; Yang, Y; Yin, C; Zhang, T1
Brkljačić, J; Djordjevic, A; Jelača, S; Macut, D; Teofilović, A; Veličković, N; Vojnović Milutinović, D1
Billig, H; Cui, P; Feng, Y; Hu, M; Hu, W; Li, X; Ma, T; Shao, LR; Shi, J; Tong, X; Xu, X; Zhang, F1
Aflatounian, A; Anderson, RA; Begg, DP; Bertoldo, MJ; Campbell, RE; Edwards, MC; Gilchrist, RB; Handelsman, DJ; Nagarkar, R; Padmanabhan, V; Rodriguez Paris, V; Sucquart, IE; Walters, KA1
Davenport, K; Everman, SJ; Logan, MK; Pruett, JE; Romero, DG; Torres Fernandez, ED; Vinson, RM; Yanes Cardozo, LL; Ye, SA1
Basnet, J; Huffman, AM; Rezq, S; Romero, DG; Yanes Cardozo, LL1
Alamgir, R; Andrisse, S; Bogle, D; Ecelbarger, C; Eregha, N; Lofton, T; McWhorter, P; Myer, J; Seidu, T1
Billig, H; Brännström, M; Hu, M; Ma, S; Sferruzzi-Perri, AN; Shao, LR; Wang, X; Wu, X; Yang, F; Zhang, D; Zhang, Y1
Kathryn Korkidakis, A; Reid, RL1
Benrick, A; Carlström, M; Cushman, SW; Fornes, R; Hu, M; Ivarsson, N; Maciel, GAR; Maliqueo, M; Marcondes, RR; Stener-Victorin, E; Stenkula, KG1
Antić, IB; Bursać, B; Djordjevic, A; Macut, D; Macut, JB; Matić, G; Milutinović, DV; Nestorov, J; Nikolić, M; Teofilović, A; Veličković, N; Zidane, AS1
Benrick, A; Chanclón, B; Hadi, L; Micallef, P; Shelton, JM; Stener-Victorin, E; Wernstedt Asterholm, I; Wu, Y1
Lee, DR; Lim, JJ; Lima, PDA; Salehi, R; Tsang, BK1
Cohen-Tannoudji, J; di Clemente, N; El Hachem, H; Fanchin, R; Giton, F; Grynberg, M; Monniaux, D; Pierre, A; Racine, C; Taieb, J; Touleimat, S1
Chen, ZJ; Fan, HY; Ji, SY; Li, BT; Liu, HB; Liu, J; Liu, XM; Zhang, YC; Zhang, YL1
Gao, J; Jia, L; Li, X; Liu, M; Ma, S; Sun, J; Tsang, SY; Wang, M; Xu, Y; Zhang, H1
Campbell, RE; Prescott, M; Silva, MS1
Chen, YA; Cheung, A; Leader, A; Lima, PDA; Nivet, AL; Tsang, BK; Tzeng, CR; Wang, Q1
An, X; Chen, Z; Cui, P; Feng, Y; Han, S; Li, B; Ma, T; Shao, LR; Tamadon, A; Wang, Y1
Hu, Q; Jin, J; Liu, P; Qian, W; Sheng, L; Tang, C; Wang, X; Yu, D; Zhang, J; Zhong, Y; Zhou, H; Zhou, Y1
Ding, G; Huang, H; Li, J; Liu, X; Liu, Y; Pan, J; Sheng, J; Wang, F; Wang, Y; Wu, Y; Xu, J; Zhou, C1
Cui, P; Feng, Y; Hu, W; Li, X; Ma, T; Shao, LR; Tong, X; Zhang, F1
Gu, HC; Hou, M; Huang, HF; Jiang, ZR; Lin, J; Liu, XM; Sheng, JZ; Wang, HH; Wu, YM; Wu, YT; Yang, Q; Zhou, CL1
Moulana, M1
Christopoulos, G; Coates, M; Franks, S; Hardy, K; Lavery, S; Lerner, A; Liyanage, M; Owens, LA; Poole, G; Simpson, C; Velupillai, J1
Bender, JR; Leone, CA; Stachenfeld, NS; Steele, FE; Taylor, HS; Usselman, CW; Yarovinsky, TO1
Li, MX; Sun, LF; Xiao, TX; Yang, YL; Zhang, JV1
Billig, H; Brännström, M; Cui, P; Guo, X; Han, Y; Hu, M; Jia, W; Lager, S; Li, J; Li, W; Liu, G; Sferruzzi-Perri, AN; Shao, LR; Wu, XK; Xu, H; Zhang, Y; Zhao, W1
Irahara, M; Iwasa, T; Kawakita, T; Matsuzaki, T; Mayila, Y; Yanagihara, R1
Andersson, D; Benrick, A; Carlström, M; Fornes, R; Manti, M; McCann Haworth, S; Pironti, G; Stener-Victorin, E; Zhengbing, Z1
Menaker, M; Murphy, ZC; Sellix, MT1
Cui, Y; Dai, X; Liu, J; Wang, J; Yan, X; Zhao, N1
Butler, MS; Hickey, TE; Liang, X; Norman, RJ; Ricciardelli, C; Tilley, WD; Yang, X1
Danser, AH; de Vries, R; Garrelds, IM; Kramer, P; Labruijere, S; Musterd-Bagghoe, UM; Van Den Brink, AM; van Houten, EL; Villalón, CM; Visser, JA1
Benko, R; Benyó, Z; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Nadasy, GL; Novak, A; Revesz, C; Ruisanchez, E; Sara, L; Tarszabo, R; Tokes, AM; Varbiro, S1
Check, JH; Cohen, R1
Bjekić-Macut, J; Božić-Antić, I; Korićanac, G; Macut, D; Matić, G; Nikolić, M; Romić, S; Tepavčević, S; Vojnović Milutinović, D; Žakula, Z1
Alrasheed, H; Damiani, GR; De Pergola, G; De Salvia, MA; Loverro, G; Montagnani, M; Tartagni, M; Tartagni, MV1
Chua, AK; Goodarzi, MO; Jiang, H; Liu, NA; Xu, N1
Antal, P; Benkő, R; Csibi, N; Monori-Kiss, A; Monos, E; Nádasy, GL; Novak, A; Paragi, P; Sára, L; Szekeres, M; Tarszabo, R; Tőkés, AM; Várbíró, S1
Antić, IB; Bursać, B; Djordjevic, A; Macut, D; Macut, JB; Matić, G; Nestorović, N; Nikolić, M; Veličković, N; Vojnović Milutinović, D1
Brabant, G; Harger, A; Hofer, D; Keevil, B; Lerchbaum, E; Münzker, J; Obermayer-Pietsch, B; Owen, L; Pieber, T; Trummer, C; Ulbing, M1
Erbas, O; Ergenoglu, M; Karadadas, N; Taskiran, D; Yavasoglu, A; Yeniel, O; Yildirim, AG; Yildirim, N1
Bui, E; do Carmo, JM; Granger, JP; Hall, JE; Lima, R; Maranon, R; Moulana, M; Reckelhoff, JF; Smith, AD; Spradley, FT; Thomas, RL; Zhang, H1
Bjekić-Macut, J; Božić-Antić, I; Korićanac, G; Macut, D; Matić, G; Milutinović, DV; Nikolić, M; Rodaljević, S; Stanišić, J; Tepavčević, S1
Bi, J; Hoang, V; Mohankumar, SM; Vyas, AK1
Grayson, BE; Ressler, IB; Seeley, RJ; Ulrich-Lai, YM1
Casson, P; Hurliman, A; Keller Brown, J; Maille, N; Mandala, M; Osol, G1
Billig, H; Cui, P; Feng, Y; Guo, YR; Hu, M; Jiang, HY; Li, X; Pishdari, B; Shao, R; Yang, HP1
Chen, L; Huang, C; Ma, BH; Pan, YF; Ren, PG; Tang, M; Tsang, BK; Wang, BB; Wang, YF; Xiao, TX; Zabel, BA; Zhang, JV; Zhao, HY1
Flück, CE; Galván, JA; Marti, N; Müller, M; Pandey, AV; Perren, A; Tapia, C; Trippel, M1
Goto, M; Iwase, A; Kikkawa, F; Kondo, M; Kotani, T; Nakahara, T; Nakamura, T; Osuka, S; Saito, A; Takikawa, S1
Ambroziak, U; Bartoszewicz, Z; Bednarczuk, T; Dadlez, M; Jaźwiec, R; Kępczyńska-Nyk, A; Kondracka, A; Kuryłowicz, A; Samborowska, E; Wysłouch-Cieszyńska, A1
Azziz, R; Magoffin, D; Nguyen, M; Pall, M1
Andres, J; Bobbert, T; Diederich, S; Hartmann, MF; Mai, K; Maser-Gluth, C; Möhlig, M; Pfeiffer, AF; Reinecke, F; Schulte, HM; Spranger, J; Weickert, MO; Wudy, SA1
Cajander, S; Lönn, M; Mannerås, L; Stener-Victorin, E1
Cabri, P; De Sutter, P; Deforce, D; Dhont, M; Stoop, D; Van Nieuwerburgh, F1
Billig, H; Feng, Y; Fernandez-Rodriguez, J; Johansson, J; Mannerås, L; Shao, R; Stener-Victorin, E1
Abbott, DH; Herkimer, C; Padmanabhan, V; Recabarren, SE; Veiga-Lopez, A1
Li, ZL; Lin, H; Liu, YM; Wang, SH; Wu, CY; Wu, XY; Xiao, WF1
Ortega, HH; Padmanabhan, V; Rey, F; Velazquez, MM1
Ding, GL; Dong, MY; Huang, HF; Lu, XE; Lv, PP; Qu, F; Sheng, JZ; Shi, BW; Wang, FF; Zhang, D1
Keller, SR; Moenter, SM; Nunemaker, CS; Roland, AV1
Davis, DD; Lima, R; Lockhart, R; Moulana, M; Racusen, LC; Reckelhoff, JF; Romero, DG; Yanes, LL; Zhang, H1
Seeley, RJ; Wilson-Pérez, HE1
Billig, H; Egecioglu, E; Feng, Y; Johansson, J; Shao, R; Stener-Victorin, E; Sun, S; Wang, T; Wang, W; Weijdegård, B1
Casson, P; Keller, J; Mandala, M; Osol, G1
Antal, P; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Monos, E; Nadasy, GL; Sara, L; Varbiro, S1
Karels, B; Kramer, P; McLuskey, A; Themmen, AP; van Houten, EL; Visser, JA1
Billig, H; Feng, Y; Johansson, J; Mannerås-Holm, L; Shao, R; Stener-Victorin, E1
Ding, GL; El-Prince, M; Gao, Q; Huang, HF; Huang, YT; Jin, M; Leung, PC; Pan, HH; Qu, F; Sheng, JZ; Shi, BW; Wang, FF; Yin, R1
Li, S; Liu, W; Mao, X; Tao, T; Wang, L; Zhang, P; Zhao, A1
Antal, P; Masszi, G; Monori-Kiss, A; Monos, E; Nadasy, GL; Sara, L; Szekeres, M; Varbiro, S1
Brown, RE; Caraty, A; Imran, SA; Wilkinson, DA; Wilkinson, M1
Kim, JY; Leader, A; Liu, JY; Tsang, BK; Wang, Q; Xue, K1
Benko, R; Benyó, Z; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Nadasy, GL; Novak, A; Revesz, C; Sara, L; Tarszabo, R; Varbiro, S1
Billig, H; Johansson, J; Lönn, M; Mannerås-Holm, L; Olsson, A; Shao, R; Stener-Victorin, E1
Baracat, EC; de Lima, GR; Haidar, MA; Lakryc, EM; Motta, EL; Soares, JM1
Allolio, B; Arlt, W; Fassnacht, M; Schlenz, N; Schneider, SB; Wudy, SA1
Tomboc, M; Witchel, SF1
Dunaif, A; Gnatuk, CL; Kunselman, AR; Legro, RS1
Marouliss, GB; Triantafillidis, IK1
Cajander, S; Holmäng, A; Lönn, M; Lystig, T; Mannerås, L; Seleskovic, Z; Stener-Victorin, E1
Al-Hendy, A; Fadl, AA; Jamaluddin, M; Nagamani, M; Salama, SA; Salih, SM1
Holmäng, A; Jonsdottir, IH; Lönn, M; Mannerås, L; Stener-Victorin, E1
Baxendale, PM; Jacobs, HS; James, VH1
Lobo, RA; Shoupe, D1
Kuttenn, F; Mauvais-Jarvis, P; Mowszowicz, I1
Hammond, GL; Kuhn, RW; Murai, JT; Nisker, JA; Raymoure, WJ; Siiteri, PK1
Hiroi, M; Kawagoe, S1
Cunliffe, WJ; Early, AS; Katz, M; Keczkes, K; McGarrigle, HH; Reese, RA; Walton, S1
Chang, L; Duffy, DM; Legro, RS; Lobo, RA; Stanczyk, FZ1
Gerris, J; Joostens, M; Mahler, C; Van der Meer, S; Van Royen, E; Verhelst, J1
Gjønnaess, H1
Jakimiuk, AJ; Magoffin, DA; Weitsman, SR1
Demisch, K; Magnet, W; Neubauer, M; Schöffling, K1
Mahesh, VB; Mattar, E; Toledo, SP1
Besch, PK; Buttram, VC; Dill, B; Smith, RG1
Kuttenn, F; Lecomte, P; Mandelbaum, J; Mauvais-Jarvis, P; Mowszowicz, I1
Bidlingmaier, F; Hammerstein, J; Moltz, L; Römmler, A; Schwartz, U1
Burger, CW; Gooren, LJ; Hompes, PG; Spijkstra, JJ; Spinder, T; van den Tweel, JG; van Kessel, H1
Lobo, RA1
Molta, L; Schwartz, U1
Aliffi, A; Calogero, A; Coniglione, F; D'Agata, R; Macchi, M; Maugeri, G; Mongioi, A; Sipione, C; Vicari, E1
Dunaif, A1
Lobo, RA; Serafini, P1
Franks, S; James, VH; Reed, MJ; Scanlon, MJ; Whorwood, CB1
Kelver, ME; Nagamani, M; Van Dinh, T1
Aakvaag, A; Gjønnaess, H1
Hirakawa, S; Ito, A; Mori, Y; Sato, W1
Hallberg, MC; Wieland, RG; Zorn, EM1
Rosenfield, RL1
Horton, R; Ito, T1

Reviews

8 review(s) available for dihydrotestosterone and Polycystic Ovarian Syndrome

ArticleYear
A meta-analysis: Effect of androgens on reproduction in sows.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Androgens; Animals; Dihydrotestosterone; Female; Humans; Male; Ovulation; Polycystic Ovary Syndrome; Swine

2023
Testosterone in Women: Measurement and Therapeutic Use.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2017, Volume: 39, Issue:3

    Topics: Androgens; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estrogen Replacement Therapy; Female; Hirsutism; Humans; Polycystic Ovary Syndrome; Radioimmunoassay; Sexual Dysfunctions, Psychological; Testosterone

2017
Polycystic ovarian disease: the adrenal connection.
    Pediatric endocrinology reviews : PER, 2006, Volume: 3 Suppl 1

    Topics: Adrenal Glands; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dihydrotestosterone; Female; Glucocorticoids; Humans; Hyperandrogenism; Polycystic Ovary Syndrome; Testosterone

2006
Hirsutism.
    Monographs on endocrinology, 1981, Volume: 19

    Topics: 17-Ketosteroids; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Androgens; Androstane-3,17-diol; Androstenedione; Cells, Cultured; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Female; Fibroblasts; Hirsutism; Humans; Liver; Male; Metabolic Clearance Rate; Ovarian Neoplasms; Polycystic Ovary Syndrome; Sebaceous Glands; Sex Hormone-Binding Globulin; Skin; Testosterone

1981
The serum transport of steroid hormones.
    Recent progress in hormone research, 1982, Volume: 38

    Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Hormones; Humans; Hydrocortisone; Kinetics; Male; Menstruation; Obesity; Ovarian Neoplasms; Polycystic Ovary Syndrome; Reference Values; Sex Hormone-Binding Globulin; Steroids; Transcortin

1982
Disturbances of androgen secretion and metabolism in polycystic ovary syndrome.
    Clinics in obstetrics and gynaecology, 1985, Volume: 12, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hirsutism; Humans; Ovary; Polycystic Ovary Syndrome; Testosterone

1985
Gonadal and adrenal androgen secretion in hirsute females.
    Clinics in endocrinology and metabolism, 1986, Volume: 15, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Androstenedione; Catheterization; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Hirsutism; Humans; Ovarian Neoplasms; Ovary; Polycystic Ovary Syndrome; Testosterone

1986
Relationship of androgens to female hirsutism and infertility.
    The Journal of reproductive medicine, 1973, Volume: 11, Issue:3

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Androstenedione; Androstenols; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hirsutism; Humans; Hydroxysteroids; Infertility, Female; Ovary; Ovulation; Polycystic Ovary Syndrome; Protein Binding; Secretory Rate; Testosterone

1973

Trials

6 trial(s) available for dihydrotestosterone and Polycystic Ovarian Syndrome

ArticleYear
Androgens drive microvascular endothelial dysfunction in women with polycystic ovary syndrome: role of the endothelin B receptor.
    The Journal of physiology, 2019, Volume: 597, Issue:11

    Topics: Adult; Androgens; Cardiovascular Diseases; Dihydrotestosterone; Endothelin-1; Endothelium, Vascular; Estrogens; Ethinyl Estradiol; Female; Glucose Tolerance Test; Humans; Microvessels; Nitric Oxide; Obesity; Polycystic Ovary Syndrome; Receptor, Endothelin B; Skin; Vascular Endothelial Growth Factor A; Vasodilation; Young Adult

2019
Intermittent low-dose finasteride administration is effective for treatment of hirsutism in adolescent girls: a pilot study.
    Journal of pediatric and adolescent gynecology, 2014, Volume: 27, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Adolescent; Androstenediol; Dihydrotestosterone; Female; Finasteride; Glucuronides; Hirsutism; Humans; Patient Satisfaction; Pilot Projects; Polycystic Ovary Syndrome; Severity of Illness Index; Young Adult

2014
Intravenous lipid and heparin infusion-induced elevation in free fatty acids and triglycerides modifies circulating androgen levels in women: a randomized, controlled trial.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:10

    Topics: Adult; Androgens; Androstenedione; Cross-Over Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Fatty Acids, Nonesterified; Female; Heparin; Humans; Infusions, Intravenous; Lipids; Polycystic Ovary Syndrome; Sodium Chloride; Testosterone; Time Factors; Triglycerides

2008
The benefits of finasteride for hirsute women with polycystic ovary syndrome or idiopathic hirsutism.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2003, Volume: 17, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; 5-alpha Reductase Inhibitors; Adult; Androstenedione; Body Mass Index; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Double-Blind Method; Enzyme Inhibitors; Female; Finasteride; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Ovary; Placebos; Polycystic Ovary Syndrome; Prolactin; Testosterone; Ultrasonography

2003
Beyond adrenal and ovarian androgen generation: Increased peripheral 5 alpha-reductase activity in women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:6

    Topics: Adult; Androgens; Cholestenone 5 alpha-Reductase; Cross-Over Studies; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Female; Glucocorticoids; Hormones; Humans; Oxidoreductases; Polycystic Ovary Syndrome

2003
Changes in glucose tolerance over time in women with polycystic ovary syndrome: a controlled study.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dihydrotestosterone; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Humans; Luteinizing Hormone; Menstrual Cycle; Polycystic Ovary Syndrome; Reference Values; Sex Hormone-Binding Globulin; Testosterone; Time Factors

2005

Other Studies

125 other study(ies) available for dihydrotestosterone and Polycystic Ovarian Syndrome

ArticleYear
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome.
    Molecular human reproduction, 2021, 11-27, Volume: 27, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Dihydrotestosterone; Disease Models, Animal; Female; Ferroptosis; Glutathione; Insulin Resistance; Iron; Male; Malondialdehyde; Mitochondria; Oxidative Phosphorylation; Phospholipid Hydroperoxide Glutathione Peroxidase; Placenta; Polycystic Ovary Syndrome; Pregnancy; Rats, Sprague-Dawley; Signal Transduction; Uterus

2021
Electroacupuncture improves metabolic and ovarian function in a rat model of polycystic ovary syndrome by decreasing white adipose tissue, increasing brown adipose tissue, and modulating the gut microbiota.
    Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2022, Volume: 40, Issue:4

    Topics: Adipose Tissue; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Diabetes Mellitus, Type 2; Dihydrotestosterone; Electroacupuncture; Female; Gastrointestinal Microbiome; Polycystic Ovary Syndrome; Rats

2022
Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons.
    Journal of neuroendocrinology, 2022, Volume: 34, Issue:4

    Topics: Androgens; Animals; Dihydrotestosterone; Female; Gonadotropin-Releasing Hormone; Humans; Hyperandrogenism; Luteinizing Hormone; Male; Mice; Neurons; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects

2022
Conversion of Classical and 11-Oxygenated Androgens by Insulin-Induced AKR1C3 in a Model of Human PCOS Adipocytes.
    Endocrinology, 2022, 07-01, Volume: 163, Issue:7

    Topics: Adipocytes; Aldo-Keto Reductase Family 1 Member C3; Androgens; Androstenes; Dihydrotestosterone; Female; Humans; Insulin; Polycystic Ovary Syndrome; Testosterone

2022
Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model.
    American journal of physiology. Endocrinology and metabolism, 2022, 08-01, Volume: 323, Issue:2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Female; Hyperandrogenism; Mice; Muscle, Skeletal; Phenotype; Polycystic Ovary Syndrome; Receptors, Androgen

2022
Comparison of Reproductive Function Between Normal and Hyperandrogenemia Conditions in Female Mice With Deletion of Hepatic Androgen Receptor.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Animals; Dihydrotestosterone; Female; Glucose; Humans; Hyperandrogenism; Liver; Mice; Obesity; Polycystic Ovary Syndrome; Receptors, Androgen; Reproduction

2022
Declining muscle NAD
    Molecular metabolism, 2022, Volume: 65

    Topics: Animals; Dihydrotestosterone; Female; Humans; Hyperandrogenism; Insulin Resistance; Lipids; Metabolic Syndrome; Mice; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Obesity; Polycystic Ovary Syndrome

2022
Structural and functional changes in rat uterus induced by neonatal androgenization.
    Journal of molecular histology, 2022, Volume: 53, Issue:6

    Topics: Androgens; Animals; Dihydrotestosterone; Female; Humans; Polycystic Ovary Syndrome; Rats; Testosterone; Uterus; Virilism

2022
Enhanced pup retrieval behaviour in a mouse model of polycystic ovary syndrome.
    Journal of neuroendocrinology, 2022, Volume: 34, Issue:12

    Topics: Androgens; Animals; Dihydrotestosterone; Estrogen Receptor alpha; Female; Maternal Behavior; Mice; Polycystic Ovary Syndrome; Pregnancy; Reproduction; Virilism

2022
Differential Strain-dependent Ovarian and Metabolic Responses in a Mouse Model of PCOS.
    Endocrinology, 2023, 02-11, Volume: 164, Issue:4

    Topics: Animals; Body Weight; Diabetes Mellitus, Type 1; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred NOD; Polycystic Ovary Syndrome

2023
Quantitation of 5α-androstanedione in normal women and women with PCOS.
    The Journal of steroid biochemistry and molecular biology, 2023, Volume: 231

    Topics: Androgens; Androstenedione; Dihydrotestosterone; Female; Humans; Male; Polycystic Ovary Syndrome; Testosterone

2023
Effects of early life overnutrition and hyperandrogenism on spatial learning and memory in a rat model of polycystic ovary syndrome.
    Hormones and behavior, 2023, Volume: 153

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Hyperandrogenism; Insulin; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Rats; Spatial Learning

2023
Neuronal Ptpn1 and Socs3 deletion improves metabolism but not anovulation in a mouse polycystic ovary syndrome model.
    The Journal of endocrinology, 2023, 09-01, Volume: 259, Issue:1

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin; Mice; Mice, Knockout; Neurons; Obesity; Polycystic Ovary Syndrome; Protein Tyrosine Phosphatase, Non-Receptor Type 1

2023
Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects.
    Journal of ovarian research, 2023, Aug-31, Volume: 16, Issue:1

    Topics: Animals; Apoptosis; Dihydrotestosterone; Female; Granulosa Cells; Humans; Ki-67 Antigen; Neuropeptide Y; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; RNA, Messenger

2023
Defective Uterine Spiral Artery Remodeling and Placental Senescence in a Pregnant Rat Model of Polycystic Ovary Syndrome.
    The American journal of pathology, 2023, Volume: 193, Issue:12

    Topics: Animals; Arteries; Dihydrotestosterone; Female; Humans; Hyperandrogenism; Insulin; Placenta; Polycystic Ovary Syndrome; Pregnancy; Rats; Uterine Artery; Uterus

2023
N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2023, Oct-26, Volume: 39, Issue:1

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Androgens; Animals; Dihydrotestosterone; Female; Granulosa Cells; Humans; Hyperandrogenism; Ligases; Polycystic Ovary Syndrome; Prostate-Specific Antigen; Proto-Oncogene Proteins c-akt; Rats

2023
Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:10

    Topics: Acetylcholine; Animals; Calcium Signaling; Carbachol; Colon; Dihydrotestosterone; Disease Models, Animal; Female; Gastrointestinal Diseases; Gastrointestinal Motility; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Phosphorylation; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Stomach

2020
Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome.
    Scientific reports, 2020, 01-23, Volume: 10, Issue:1

    Topics: Androgens; Animals; Apoptosis; Autophagy; Dihydrotestosterone; Disease Models, Animal; Dynamins; Female; Gonadotropins; Granulosa Cells; Mitochondria; Mitochondrial Dynamics; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley

2020
Effect of DHT-Induced Hyperandrogenism on the Pro-Inflammatory Cytokines in a Rat Model of Polycystic Ovary Morphology.
    Medicina (Kaunas, Lithuania), 2020, Feb-27, Volume: 56, Issue:3

    Topics: Animals; Cytokines; Dihydrotestosterone; Disease Models, Animal; Female; Follicle Stimulating Hormone; Hyperandrogenism; Inflammation Mediators; Insulin; Liver; Luteinizing Hormone; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Urocortins

2020
Characterization on gut microbiome of PCOS rats and its further design by shifts in high-fat diet and dihydrotestosterone induction in PCOS rats.
    Bioprocess and biosystems engineering, 2021, Volume: 44, Issue:5

    Topics: Animals; Diet, High-Fat; Dihydrotestosterone; Female; Gastrointestinal Microbiome; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley

2021
Pigment epithelium-derived factor (PEDF) negates hyperandrogenic PCOS features.
    The Journal of endocrinology, 2020, Volume: 245, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Dihydrotestosterone; Disease Models, Animal; Eye Proteins; Female; Granulosa Cells; Humans; Hyperandrogenism; Mice; Nerve Growth Factors; Ovary; Polycystic Ovary Syndrome; Serpins; Signal Transduction

2020
Androgen Action in Adipose Tissue and the Brain are Key Mediators in the Development of PCOS Traits in a Mouse Model.
    Endocrinology, 2020, 07-01, Volume: 161, Issue:7

    Topics: Adipose Tissue; Animals; Brain; Dihydrotestosterone; Disease Models, Animal; Female; Male; Mice, Knockout; Polycystic Ovary Syndrome; Receptors, Androgen

2020
Hyperandrogenic Milieu Dysregulates the Expression of Insulin Signaling Factors and Glucose Transporters in the Endometrium of Patients With Polycystic Ovary Syndrome.
    Reproductive sciences (Thousand Oaks, Calif.), 2020, Volume: 27, Issue:8

    Topics: Androgens; Antigens, CD; Cells, Cultured; Dihydrotestosterone; Endometrium; Female; Glucose Transport Proteins, Facilitative; Humans; Insulin; Polycystic Ovary Syndrome; Receptor, Insulin; Signal Transduction

2020
D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome.
    International journal of molecular sciences, 2020, Aug-22, Volume: 21, Issue:17

    Topics: Aging; Animals; Blastocyst; Cumulus Cells; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression Regulation; Glucose Intolerance; Infertility, Female; Inositol; Liver; Male; Mice, Inbred Strains; Oocytes; Phosphorylation; Polycystic Ovary Syndrome; Proto-Oncogene Proteins c-akt; Testosterone Propionate

2020
Troxerutin protects against DHT-induced polycystic ovary syndrome in rats.
    Journal of ovarian research, 2020, Sep-13, Volume: 13, Issue:1

    Topics: Animals; Body Weight; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gene Expression Regulation; Gene Regulatory Networks; Gonadotropin-Releasing Hormone; Gonadotropins; Hydroxyethylrutoside; Polycystic Ovary Syndrome; Rats; Testosterone

2020
Involvement of endogenous testosterone in hepatic steatosis in women with polycystic ovarian syndrome.
    The Journal of steroid biochemistry and molecular biology, 2020, Volume: 204

    Topics: Adult; AMP-Activated Protein Kinases; Androgens; Animals; Aromatase Inhibitors; Dihydrotestosterone; Female; Hep G2 Cells; Hepatocytes; Humans; Letrozole; Liver; Non-alcoholic Fatty Liver Disease; Ovary; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Testosterone; Young Adult

2020
Glucocorticoid signaling and lipid metabolism disturbances in the liver of rats treated with 5α-dihydrotestosterone in an animal model of polycystic ovary syndrome.
    Endocrine, 2021, Volume: 72, Issue:2

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Glucocorticoids; Humans; Lipid Metabolism; Liver; Polycystic Ovary Syndrome; Rats; Rats, Wistar

2021
Long-term androgen excess induces insulin resistance and non-alcoholic fatty liver disease in PCOS-like rats.
    The Journal of steroid biochemistry and molecular biology, 2021, Volume: 208

    Topics: Androgens; Animals; Apoptosis; Autophagy-Related Protein 12; bcl-2 Homologous Antagonist-Killer Protein; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin Resistance; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Obesity; Polycystic Ovary Syndrome; Reactive Oxygen Species; Risk Factors

2021
Neurokinin 3 Receptor Antagonism Ameliorates Key Metabolic Features in a Hyperandrogenic PCOS Mouse Model.
    Endocrinology, 2021, 05-01, Volume: 162, Issue:5

    Topics: Androgens; Animals; Blood Glucose; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Hyperandrogenism; Lectins; Membrane Proteins; Mice; Mice, Inbred C57BL; Polycystic Ovary Syndrome; Receptors, Neurokinin-3; Triglycerides

2021
Impact of SGLT-2 Inhibition on Cardiometabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome.
    International journal of molecular sciences, 2021, Mar-04, Volume: 22, Issue:5

    Topics: Animals; Benzhydryl Compounds; Dihydrotestosterone; Disease Models, Animal; Female; Glucosides; Heart; Hyperandrogenism; Polycystic Ovary Syndrome; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2021
SARS-CoV-2 Viral Entry Proteins in Hyperandrogenemic Female Mice: Implications for Women with PCOS and COVID-19.
    International journal of molecular sciences, 2021, Apr-25, Volume: 22, Issue:9

    Topics: Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Body Weight; Cathepsin L; COVID-19; Dihydrotestosterone; Female; Humans; Hyperandrogenism; Kidney; Mice; Mice, Inbred C57BL; Polycystic Ovary Syndrome; SARS-CoV-2; Serine Endopeptidases; Up-Regulation; Virus Internalization

2021
DHT causes liver steatosis via transcriptional regulation of SCAP in normal weight female mice.
    The Journal of endocrinology, 2021, 06-28, Volume: 250, Issue:2

    Topics: Animals; Body Composition; Body Weight; Dihydrotestosterone; Female; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Lipid Metabolism; Liver; Membrane Proteins; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Polycystic Ovary Syndrome; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic

2021
Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance.
    Journal of molecular medicine (Berlin, Germany), 2021, Volume: 99, Issue:10

    Topics: Androgens; Animals; Decidua; Dihydrotestosterone; Embryo Implantation; Endometrium; Female; Hyperandrogenism; Insulin; Insulin Resistance; Male; Mitochondria; Polycystic Ovary Syndrome; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Uterus

2021
Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome.
    Molecular and cellular endocrinology, 2017, 06-15, Volume: 448

    Topics: Adipocytes; Adipogenesis; Adipose Tissue, White; Animals; Body Composition; Body Weight; Cell Size; Dihydrotestosterone; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Glucose Tolerance Test; Insulin Resistance; Letrozole; Lipid Metabolism; Liver; Mice, Inbred C57BL; Nitriles; Organ Size; Phenotype; Physical Conditioning, Animal; Polycystic Ovary Syndrome; Signal Transduction; Triazoles; Triglycerides

2017
Enhanced Inflammation without Impairment of Insulin Signaling in the Visceral Adipose Tissue of 5α-Dihydrotestosterone-Induced Animal Model of Polycystic Ovary Syndrome.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2017, Volume: 125, Issue:8

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Inflammation; Insulin; Interleukin-1beta; Interleukin-6; Intra-Abdominal Fat; Obesity, Abdominal; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Signal Transduction

2017
Adiponectin protects against development of metabolic disturbances in a PCOS mouse model.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 08-22, Volume: 114, Issue:34

    Topics: Adiponectin; Adipose Tissue; Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin Resistance; Mice; Mice, Knockout; Polycystic Ovary Syndrome

2017
Regulation of androgen receptor signaling by ubiquitination during folliculogenesis and its possible dysregulation in polycystic ovarian syndrome.
    Scientific reports, 2017, 08-31, Volume: 7, Issue:1

    Topics: Animals; Biomarkers; Dihydrotestosterone; Disease Models, Animal; Female; Gonadotropins; Humans; Ovarian Follicle; Polycystic Ovary Syndrome; Rats; Receptors, Androgen; Signal Transduction; Stem Cell Factor; Ubiquitination

2017
Dysregulation of the Anti-Müllerian Hormone System by Steroids in Women With Polycystic Ovary Syndrome.
    The Journal of clinical endocrinology and metabolism, 2017, 11-01, Volume: 102, Issue:11

    Topics: Adult; Anti-Mullerian Hormone; Case-Control Studies; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Follicular Phase; Gene Expression Regulation; Granulosa Cells; Humans; Polycystic Ovary Syndrome; Receptors, Androgen; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Young Adult

2017
The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse.
    Molecular human reproduction, 2017, 10-01, Volume: 23, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Proliferation; Chorionic Gonadotropin; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression Regulation; Gonadotropins, Equine; Granulosa Cells; Horses; Humans; Hyperandrogenism; Luteinizing Hormone; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovary; Ovulation; Phosphoproteins; Polycystic Ovary Syndrome; Primary Cell Culture; Signal Transduction; YAP-Signaling Proteins

2017
MicroRNA-27a-3p affects estradiol and androgen imbalance by targeting Creb1 in the granulosa cells in mouse polycytic ovary syndrome model.
    Reproductive biology, 2017, Volume: 17, Issue:4

    Topics: Androgens; Animals; Apoptosis; Aromatase; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Granulosa Cells; Mice; MicroRNAs; Polycystic Ovary Syndrome; Testosterone

2017
Ontogeny and reversal of brain circuit abnormalities in a preclinical model of PCOS.
    JCI insight, 2018, 04-05, Volume: 3, Issue:7

    Topics: Androgen Receptor Antagonists; Androgens; Animals; Brain; Dihydrotestosterone; Feedback, Physiological; Female; GABAergic Neurons; Gonadotropin-Releasing Hormone; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Ovary; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Androgen; Virilism

2018
Polycystic ovary syndrome: possible involvement of androgen-induced, chemerin-mediated ovarian recruitment of monocytes/macrophages.
    Biology of reproduction, 2018, 10-01, Volume: 99, Issue:4

    Topics: Androgens; Animals; Apoptosis; Cell Movement; Chemokines; Dihydrotestosterone; Disease Models, Animal; Female; Granulosa Cells; Humans; Hyperandrogenism; Intercellular Signaling Peptides and Proteins; Macrophages; Monocytes; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Receptors, Chemokine

2018
Hypothalamic DNA methylation in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture.
    Experimental physiology, 2018, Volume: 103, Issue:12

    Topics: Acupuncture Therapy; Animals; Body Weight; CpG Islands; Dihydrotestosterone; DNA Methylation; Electroacupuncture; Female; Hypothalamus; Insulin Resistance; Polycystic Ovary Syndrome; Rats; Rats, Wistar

2018
Crocetin attenuates DHT-induced polycystic ovary syndrome in mice via revising kisspeptin neurons.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Carotenoids; Crocus; Dihydrotestosterone; Disease Models, Animal; Drugs, Chinese Herbal; Estrous Cycle; Female; Hypothalamo-Hypophyseal System; Hypothalamus, Anterior; Kisspeptins; Neurons; Ovary; Polycystic Ovary Syndrome; Vitamin A

2018
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
    Science China. Life sciences, 2019, Volume: 62, Issue:2

    Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Alternative Splicing; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Dihydrotestosterone; Female; Gene Expression; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Polycystic Ovary Syndrome; Protein Binding; Receptors, Androgen

2019
Endogenous Ovarian Angiogenesis in Polycystic Ovary Syndrome-Like Rats Induced by Low-Frequency Electro-Acupuncture: The CLARITY Three-Dimensional Approach.
    International journal of molecular sciences, 2018, Nov-07, Volume: 19, Issue:11

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Electroacupuncture; Female; Imaging, Three-Dimensional; Neovascularization, Physiologic; Ovarian Follicle; Ovary; Polycystic Ovary Syndrome; Rats, Wistar

2018
Prenatal exposure to testosterone induces cardiac hypertrophy in adult female rats through enhanced Pkcδ expression in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2019, Volume: 128

    Topics: Acetophenones; Androgens; Animals; Animals, Newborn; Benzopyrans; Cardiomegaly; Dihydrotestosterone; Female; Gene Expression Regulation; Humans; Myocytes, Cardiac; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C-delta; Rats; Receptors, Androgen; Signal Transduction; Testosterone; Tetradecanoylphorbol Acetate

2019
Immunophenotypic profile of leukocytes in hyperandrogenemic female rat an animal model of polycystic ovary syndrome.
    Life sciences, 2019, Mar-01, Volume: 220

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Hyperandrogenism; Immunophenotyping; Leukocytes; Phenotype; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; T-Lymphocytes, Regulatory; Th17 Cells

2019
Expression of genes controlling steroid metabolism and action in granulosa-lutein cells of women with polycystic ovaries.
    Molecular and cellular endocrinology, 2019, 04-15, Volume: 486

    Topics: Adult; Androgens; Body Mass Index; Cells, Cultured; Dihydrotestosterone; Estradiol; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Gene Regulatory Networks; Granulosa Cells; Humans; In Vitro Oocyte Maturation Techniques; Luteal Cells; Models, Biological; Ovulation; Polycystic Ovary Syndrome; Receptors, Estrogen; Reference Standards; Steroids

2019
Removal of DHT can relieve polycystic ovarian but not metabolic abnormalities in DHT-induced hyperandrogenism in mice.
    Reproduction, fertility, and development, 2019, Volume: 31, Issue:10

    Topics: Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Female; Gene Expression; Hyperandrogenism; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Ovary; Polycystic Ovary Syndrome; Stimulation, Chemical; Time Factors

2019
Hyperandrogenism and insulin resistance-induced fetal loss: evidence for placental mitochondrial abnormalities and elevated reactive oxygen species production in pregnant rats that mimic the clinical features of polycystic ovary syndrome.
    The Journal of physiology, 2019, Volume: 597, Issue:15

    Topics: Abortion, Spontaneous; Animals; Dihydrotestosterone; Female; Glycogen; Hyperandrogenism; Insulin Resistance; Kelch-Like ECH-Associated Protein 1; Mitochondria; NF-E2-Related Factor 2; Polycystic Ovary Syndrome; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase-1; Trophoblasts

2019
The effects of chronic oxytocin administration on body weight and food intake in DHT-induced PCOS model rats.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:1

    Topics: Adipocytes; Alanine Transaminase; Androgens; Animals; Aspartate Aminotransferases; Body Weight; Cell Size; Dihydrotestosterone; Disease Models, Animal; Eating; Female; Intra-Abdominal Fat; L-Lactate Dehydrogenase; Ovarian Cysts; Ovary; Oxytocics; Oxytocin; Polycystic Ovary Syndrome; Rats

2020
Maternal androgen excess induces cardiac hypertrophy and left ventricular dysfunction in female mice offspring.
    Cardiovascular research, 2020, 03-01, Volume: 116, Issue:3

    Topics: Animals; Diet, High-Fat; Dietary Sucrose; Dihydrotestosterone; Disease Models, Animal; Energy Metabolism; Female; Gene Expression Regulation; Hypertrophy, Left Ventricular; Maternal Exposure; Mesenteric Arteries; Mice, Inbred C57BL; Myocardium; NADPH Oxidases; Obesity; Polycystic Ovary Syndrome; Pregnancy; Sex Factors; Sexual Development; Sodium-Calcium Exchanger; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2020
Excess androgen during puberty disrupts circadian organization in female rats.
    Endocrinology, 2013, Volume: 154, Issue:4

    Topics: Adipose Tissue; Androgens; Animals; Body Weight; Circadian Clocks; Cornea; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Liver; Motor Activity; Ovarian Follicle; Period Circadian Proteins; Polycystic Ovary Syndrome; Rats; Rats, Transgenic; Sexual Maturation

2013
Prenatal androgen excess programs metabolic derangements in pubertal female rats.
    The Journal of endocrinology, 2013, Volume: 217, Issue:1

    Topics: Androgens; Animals; Dihydrotestosterone; Female; Fetal Development; Follicular Atresia; Glucose Intolerance; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Muscle, Skeletal; Ovarian Cysts; Ovarian Follicle; Phosphorylation; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2013
Small glutamine-rich tetratricopeptide repeat-containing protein alpha is present in human ovaries but may not be differentially expressed in relation to polycystic ovary syndrome.
    Fertility and sterility, 2013, Volume: 99, Issue:7

    Topics: Adult; Carrier Proteins; Case-Control Studies; Cell Line, Tumor; China; Dihydrotestosterone; Female; Granulosa Cell Tumor; Humans; Middle Aged; Molecular Chaperones; Ovary; Polycystic Ovary Syndrome; Protein Transport; Receptors, Androgen; RNA Interference; RNA, Messenger; South Australia; Transfection

2013
Analysis of the vascular responses in a murine model of polycystic ovary syndrome.
    The Journal of endocrinology, 2013, Volume: 218, Issue:2

    Topics: Acetylcholine; Animals; Aorta; Dihydrotestosterone; Disease Models, Animal; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Polycystic Ovary Syndrome; Vasodilation

2013
Effects of vitamin D3 derivative--calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcitriol; Dihydrotestosterone; Disease Models, Animal; Female; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasoconstriction; Vasodilation

2013
Dihydrotestosterone may contribute to the development of migraine headaches.
    Clinical and experimental obstetrics & gynecology, 2013, Volume: 40, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Contraceptives, Oral; Dextroamphetamine; Dihydrotestosterone; Female; Finasteride; Humans; Migraine Disorders; Polycystic Ovary Syndrome; Spironolactone; Young Adult

2013
Dihydrotestosterone deteriorates cardiac insulin signaling and glucose transport in the rat model of polycystic ovary syndrome.
    The Journal of steroid biochemistry and molecular biology, 2014, Volume: 141

    Topics: Animals; Biological Transport; Dihydrotestosterone; Extracellular Signal-Regulated MAP Kinases; Female; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Insulin Resistance; Myocardium; Phosphorylation; Polycystic Ovary Syndrome; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction

2014
Early embryonic androgen exposure induces transgenerational epigenetic and metabolic changes.
    Molecular endocrinology (Baltimore, Md.), 2014, Volume: 28, Issue:8

    Topics: Androgens; Animals; Blood Glucose; Dihydrotestosterone; DNA Methylation; Epigenesis, Genetic; Female; Glucose; Homeostasis; Humans; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Testosterone; Zebrafish

2014
Lower-limb veins are thicker and vascular reactivity is decreased in a rat PCOS model: concomitant vitamin D3 treatment partially prevents these changes.
    American journal of physiology. Heart and circulatory physiology, 2014, Sep-15, Volume: 307, Issue:6

    Topics: Animals; Cholecalciferol; Cyclooxygenase 2; Dihydrotestosterone; Disease Models, Animal; Female; Lower Extremity; Nitric Oxide Synthase Type III; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Saphenous Vein; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Venous Pressure

2014
Possible involvement of glucocorticoids in 5α-dihydrotestosterone-induced PCOS-like metabolic disturbances in the rat visceral adipose tissue.
    Molecular and cellular endocrinology, 2015, Jan-05, Volume: 399

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Androgens; Animals; Dihydrotestosterone; Fatty Acid Synthase, Type I; Female; Glucocorticoids; Intra-Abdominal Fat; Nuclear Proteins; Obesity; Phosphoenolpyruvate Carboxykinase (ATP); Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Glucocorticoid; Sterol Regulatory Element Binding Protein 1

2015
Testosterone to dihydrotestosterone ratio as a new biomarker for an adverse metabolic phenotype in the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Dihydrotestosterone; Female; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Metabolic Syndrome; Middle Aged; Polycystic Ovary Syndrome; Testosterone; Young Adult

2015
Effects of Resveratrol on Ovarian Morphology, Plasma Anti-Mullerian Hormone, IGF-1 Levels, and Oxidative Stress Parameters in a Rat Model of Polycystic Ovary Syndrome.
    Reproductive sciences (Thousand Oaks, Calif.), 2015, Volume: 22, Issue:8

    Topics: Animals; Anti-Mullerian Hormone; Antioxidants; Biomarkers; Dihydrotestosterone; Disease Models, Animal; Female; Glutathione Peroxidase; Insulin-Like Growth Factor I; Ovarian Follicle; Ovary; Oxidative Stress; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase

2015
Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Adrenergic Antagonists; Animals; Arterial Pressure; Dihydrotestosterone; Disease Models, Animal; Female; Hormone Antagonists; Hyperandrogenism; Hypertension; Hypothalamus; Kidney; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Signal Transduction; Sympathectomy; Sympathetic Nervous System; Time Factors

2015
Cardiac Nitric Oxide Synthases and Na⁺/K⁺-ATPase in the Rat Model of Polycystic Ovary Syndrome Induced by Dihydrotestosterone.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2015, Volume: 123, Issue:5

    Topics: Animals; Cell Membrane; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Female; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Polycystic Ovary Syndrome; Protein Processing, Post-Translational; Protein Transport; Random Allocation; Rats, Wistar; Serine; Sodium-Potassium-Exchanging ATPase; Threonine; Up-Regulation

2015
Liraglutide improves hypertension and metabolic perturbation in a rat model of polycystic ovarian syndrome.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Abdominal Fat; Animals; Blood Pressure; Cholesterol; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Glucose; Hypertension; Liraglutide; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Telemetry; Weight Gain

2015
Diet-induced obesity exacerbates metabolic and behavioral effects of polycystic ovary syndrome in a rodent model.
    American journal of physiology. Endocrinology and metabolism, 2015, Jun-15, Volume: 308, Issue:12

    Topics: Adiposity; Animals; Behavior, Animal; Body Weight; Diet, High-Fat; Dihydrotestosterone; Disease Models, Animal; Energy Intake; Female; Glucose Intolerance; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Rats; Rats, Long-Evans; Stress, Psychological

2015
Hyperandrogenism and Insulin Resistance, Not Changes in Body Weight, Mediate the Development of Endothelial Dysfunction in a Female Rat Model of Polycystic Ovary Syndrome (PCOS).
    Endocrinology, 2015, Volume: 156, Issue:11

    Topics: Androgen Antagonists; Androgens; Animals; Arteries; Blood Pressure; Body Weight; Dihydrotestosterone; Endothelium, Vascular; Female; Flutamide; Hyperandrogenism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Random Allocation; Rats, Wistar; Time Factors; Vasodilation

2015
Regulation of Androgen Receptor Expression Alters AMPK Phosphorylation in the Endometrium: In Vivo and In Vitro Studies in Women with Polycystic Ovary Syndrome.
    International journal of biological sciences, 2015, Volume: 11, Issue:12

    Topics: Adenylate Kinase; Animals; Cyclin-Dependent Kinase Inhibitor p21; Dihydrotestosterone; Endometrium; Female; Flutamide; Humans; In Vitro Techniques; Ki-67 Antigen; Phosphorylation; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Androgen

2015
CMKLR1 deficiency maintains ovarian steroid production in mice treated chronically with dihydrotestosterone.
    Scientific reports, 2016, Feb-19, Volume: 6

    Topics: Animals; Apoptosis; Dihydrotestosterone; Estrous Cycle; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Gonadal Steroid Hormones; Mice; Mice, Knockout; Ovarian Follicle; Ovary; Polycystic Ovary Syndrome; Receptors, Chemokine; Receptors, G-Protein-Coupled; Receptors, Steroid; RNA, Messenger; Steroids

2016
Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome.
    Molecular and cellular endocrinology, 2017, 02-05, Volume: 441

    Topics: Adolescent; Adrenal Glands; Adult; Biosynthetic Pathways; Child; Dihydrotestosterone; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Ovary; Polycystic Ovary Syndrome; Testis; Young Adult

2017
Kisspeptin in the Hypothalamus of 2 Rat Models of Polycystic Ovary Syndrome.
    Endocrinology, 2017, 02-01, Volume: 158, Issue:2

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Gonadal Steroid Hormones; Gonadotropins; Hypothalamo-Hypophyseal System; Hypothalamus, Anterior; Kisspeptins; Ovary; Phenotype; Polycystic Ovary Syndrome; Rats, Wistar

2017
Total testosterone to dihydrotestosterone ratio assessed by LC-MS/MS predicts a worse metabolic profile not only in PCOS patients.
    Ginekologia polska, 2017, Volume: 88, Issue:1

    Topics: Adipose Tissue; Adolescent; Adult; Androstenedione; Body Composition; Body Mass Index; Case-Control Studies; Chromatography, Liquid; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Humans; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Prognosis; Tandem Mass Spectrometry; Testosterone; Waist Circumference; Young Adult

2017
Effect of sex steroids and insulin on dehydroepiandrosterone sulfate production by hepatoma G2 cells.
    Fertility and sterility, 2009, Volume: 91, Issue:6

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Female; Humans; Insulin; Polycystic Ovary Syndrome; Testosterone

2009
Acupuncture and exercise restore adipose tissue expression of sympathetic markers and improve ovarian morphology in rats with dihydrotestosterone-induced PCOS.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: Acupuncture Therapy; Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Exercise Therapy; Female; Gene Expression Regulation; Nerve Growth Factor; Neuropeptide Y; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Adrenergic, beta-3; Receptors, Androgen; RNA, Messenger; Sympathetic Nervous System

2009
Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2008, Volume: 24, Issue:12

    Topics: Acne Vulgaris; Adult; Alleles; Androgens; Androstenedione; Dihydrotestosterone; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Hyperandrogenism; Luteinizing Hormone; Phenotype; Polycystic Ovary Syndrome; Polymorphism, Genetic; Receptors, Androgen; Trinucleotide Repeats

2008
Hypothalamic neuroendocrine functions in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture.
    PloS one, 2009, Aug-14, Volume: 4, Issue:8

    Topics: Animals; Dihydrotestosterone; Electroacupuncture; Female; Hypothalamus; Neurosecretory Systems; Polycystic Ovary Syndrome; Rats

2009
Developmental programming: impact of prenatal testosterone excess and postnatal weight gain on insulin sensitivity index and transfer of traits to offspring of overweight females.
    Endocrinology, 2010, Volume: 151, Issue:2

    Topics: Animal Feed; Animals; Dihydrotestosterone; Female; Obesity; Overweight; Polycystic Ovary Syndrome; Pregnancy; Pregnancy, Animal; Sheep; Testosterone; Weight Gain

2010
Endocrine traits of polycystic ovary syndrome in prenatally androgenized female Sprague-Dawley rats.
    Endocrine journal, 2010, Volume: 57, Issue:3

    Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Hypothalamus; Luteinizing Hormone; Nipples; Ovarian Follicle; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; RNA, Messenger; Testosterone

2010
Developmental programming: effect of prenatal steroid excess on intraovarian components of insulin signaling pathway and related proteins in sheep.
    Biology of reproduction, 2010, Volume: 82, Issue:6

    Topics: Adiponectin; Animals; Dihydrotestosterone; Female; Fetus; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Ovary; Phosphatidylinositol 3-Kinases; Polycystic Ovary Syndrome; PPAR gamma; Pregnancy; Prenatal Exposure Delayed Effects; Protein Serine-Threonine Kinases; Receptor, Insulin; Sheep; Signal Transduction; Testosterone; TOR Serine-Threonine Kinases

2010
Altered aquaporin expression in women with polycystic ovary syndrome: hyperandrogenism in follicular fluid inhibits aquaporin-9 in granulosa cells through the phosphatidylinositol 3-kinase pathway.
    Human reproduction (Oxford, England), 2010, Volume: 25, Issue:6

    Topics: Adult; Analysis of Variance; Aquaporins; Blotting, Western; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Fluorescent Antibody Technique; Follicular Fluid; Granulosa Cells; Humans; Hyperandrogenism; Luteinizing Hormone; Phosphatidylinositol 3-Kinases; Polycystic Ovary Syndrome; Reverse Transcriptase Polymerase Chain Reaction; Sex Hormone-Binding Globulin; Signal Transduction; Testosterone

2010
Prenatal androgen exposure programs metabolic dysfunction in female mice.
    The Journal of endocrinology, 2010, Volume: 207, Issue:2

    Topics: Adipocytes; Aging; Androgens; Animals; Body Composition; Calcium; Dihydrotestosterone; Female; Glucose Intolerance; Insulin; Islets of Langerhans; Mice; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects

2010
Cardiovascular-renal and metabolic characterization of a rat model of polycystic ovary syndrome.
    Gender medicine, 2011, Volume: 8, Issue:2

    Topics: Angiotensinogen; Animals; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Glomerular Filtration Rate; Glucose Tolerance Test; Kidney Diseases; Leptin; Metabolic Syndrome; Oxidative Stress; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System

2011
The effect of vertical sleeve gastrectomy on a rat model of polycystic ovarian syndrome.
    Endocrinology, 2011, Volume: 152, Issue:10

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Gastrectomy; Male; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Weight Loss

2011
Effects of androgen and leptin on behavioral and cellular responses in female rats.
    Hormones and behavior, 2011, Volume: 60, Issue:4

    Topics: Androgens; Animals; Behavior, Animal; Body Weight; Brain; Cell Physiological Phenomena; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Leptin; Maze Learning; Organ Size; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Androgen

2011
Endothelial dysfunction in a rat model of PCOS: evidence of increased vasoconstrictor prostanoid activity.
    Endocrinology, 2011, Volume: 152, Issue:12

    Topics: Acetylcholine; Animals; Dihydrotestosterone; Endothelial Cells; Endothelium, Vascular; Female; Polycystic Ovary Syndrome; Prostaglandins; Rats; Vascular Resistance; Vasoconstrictor Agents; Vasodilation

2011
Arteriolar insulin resistance in a rat model of polycystic ovary syndrome.
    Fertility and sterility, 2012, Volume: 97, Issue:2

    Topics: Acetylcholine; Animals; Arterioles; Blood Glucose; Cholecalciferol; Dihydrotestosterone; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose Tolerance Test; Insulin; Insulin Resistance; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

2012
Reproductive and metabolic phenotype of a mouse model of PCOS.
    Endocrinology, 2012, Volume: 153, Issue:6

    Topics: Adiponectin; Animals; Body Weight; Dihydrotestosterone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Humans; Immunohistochemistry; Insulin; Leptin; Lipid Metabolism; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Ovarian Follicle; Ovary; Phenotype; Polycystic Ovary Syndrome; Reproduction; Reverse Transcriptase Polymerase Chain Reaction

2012
Electrical and manual acupuncture stimulation affect oestrous cyclicity and neuroendocrine function in an 5α-dihydrotestosterone-induced rat polycystic ovary syndrome model.
    Experimental physiology, 2012, Volume: 97, Issue:5

    Topics: Acupuncture Therapy; Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Disease Models, Animal; Electroacupuncture; Estrous Cycle; Female; Polycystic Ovary Syndrome; Progesterone; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Testosterone

2012
A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.
    Journal of molecular medicine (Berlin, Germany), 2012, Volume: 90, Issue:8

    Topics: Acetylation; Animals; Anti-Mullerian Hormone; Cells, Cultured; Dihydrotestosterone; DNA Methylation; Female; Granulosa Cells; Histone Deacetylases; Humans; Hyperandrogenism; Nuclear Receptor Co-Repressor 1; Polycystic Ovary Syndrome; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley

2012
The expression of sex steroid synthesis and inactivation enzymes in subcutaneous adipose tissue of PCOS patients.
    The Journal of steroid biochemistry and molecular biology, 2012, Volume: 132, Issue:1-2

    Topics: Adiponectin; Adipose Tissue; Adult; Dihydrotestosterone; Female; Humans; Leptin; Oxidoreductases; Polycystic Ovary Syndrome; PPAR gamma; RNA, Messenger; Testosterone; Young Adult

2012
Pharmacological reactivity of resistance vessels in a rat PCOS model - vascular effects of parallel vitamin D₃ treatment.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:12

    Topics: Animals; Arterioles; Cardiovascular Agents; Cardiovascular Diseases; Cholecalciferol; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Endothelium, Vascular; Female; Injections, Subcutaneous; Muscle, Skeletal; Muscle, Smooth, Vascular; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Thigh; Vascular Resistance; Vasoconstriction; Vasodilation

2012
Hypothalamic kiss1 mRNA and kisspeptin immunoreactivity are reduced in a rat model of polycystic ovary syndrome (PCOS).
    Brain research, 2012, Jul-27, Volume: 1467

    Topics: Adipose Tissue; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dihydrotestosterone; Energy Metabolism; Female; Gonadal Steroid Hormones; Hypothalamus; Immunohistochemistry; Kisspeptins; Ovary; Pituitary Gland; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Chemerin, a novel regulator of follicular steroidogenesis and its potential involvement in polycystic ovarian syndrome.
    Endocrinology, 2012, Volume: 153, Issue:11

    Topics: Adipokines; Animals; Aromatase; Chemokines; Cholesterol Side-Chain Cleavage Enzyme; Dihydrotestosterone; Disease Models, Animal; Female; Follicle Stimulating Hormone; Gene Expression; Gonadal Steroid Hormones; Granulosa Cells; Intercellular Signaling Peptides and Proteins; Ovarian Follicle; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Steroidogenic Factor 1

2012
Altered insulin-induced relaxation of aortic rings in a dihydrotestosterone-induced rodent model of polycystic ovary syndrome.
    Fertility and sterility, 2013, Volume: 99, Issue:2

    Topics: Animals; Aorta; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasodilation; Vitamin D

2013
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Acupuncture Therapy; Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Electric Stimulation; Female; Glucose; Humans; Insulin; Muscle Contraction; Muscle, Skeletal; Musculoskeletal Manipulations; Polycystic Ovary Syndrome; Rats; Signal Transduction

2013
Frequencies of the D85 and Y85 variants of UGT2B15 in children and adolescent girls with hyperandrogenism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2003, Volume: 16, Issue:5

    Topics: Adolescent; Androstane-3,17-diol; Androstenedione; Child; Dihydrotestosterone; Female; Gene Frequency; Genotype; Glucuronosyltransferase; Heterozygote; Homozygote; Humans; Hyperandrogenism; Phenotype; Polycystic Ovary Syndrome; Puberty, Precocious; Sex Hormone-Binding Globulin; Testosterone

2003
A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome.
    Endocrinology, 2007, Volume: 148, Issue:8

    Topics: Adipocytes; Androgens; Animals; Aromatase Inhibitors; Body Composition; Body Weight; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Letrozole; Magnetic Resonance Imaging; Mesentery; Muscle, Skeletal; Nitriles; Organ Size; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Testosterone; Triazoles

2007
Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome.
    Fertility and sterility, 2008, Volume: 89, Issue:5 Suppl

    Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Proliferation; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Female; Gene Expression Regulation, Enzymologic; Granulosa Cells; Humans; Models, Biological; Ovarian Follicle; Ovulation; Polycystic Ovary Syndrome; RNA, Messenger; Steroids; Swine; Tretinoin

2008
Low-frequency electro-acupuncture and physical exercise improve metabolic disturbances and modulate gene expression in adipose tissue in rats with dihydrotestosterone-induced polycystic ovary syndrome.
    Endocrinology, 2008, Volume: 149, Issue:7

    Topics: Adipocytes; Adipose Tissue; Animals; Animals, Newborn; Dihydrotestosterone; Electroacupuncture; Female; Gene Expression Regulation; Insulin-Like Growth Factor I; Interleukin-6; Ion Channels; Leptin; Mitochondrial Proteins; Physical Conditioning, Animal; Polycystic Ovary Syndrome; Random Allocation; Rats; Reverse Transcriptase Polymerase Chain Reaction; Uncoupling Protein 2

2008
Plasma and salivary androstenedione and dihydrotestosterone in women with hyperandrogenism.
    Clinical endocrinology, 1983, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Ethinyl Estradiol; Female; Hirsutism; Humans; Polycystic Ovary Syndrome; Radioimmunoassay; Saliva

1983
The influence of androgens on insulin resistance.
    Fertility and sterility, 1984, Volume: 41, Issue:3

    Topics: Adult; Androgens; Androstane-3,17-diol; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hirsutism; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Pituitary Hormone-Releasing Hormones; Polycystic Ovary Syndrome; Spironolactone; Testosterone

1984
[A simplified method for measuring the binding capacity of sex hormone-binding globulin in human serum and its clinical application (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Jul-20, Volume: 56, Issue:7

    Topics: Adult; Age Factors; Aged; Amenorrhea; Dihydrotestosterone; Female; Hirsutism; Humans; Male; Methods; Middle Aged; Polycystic Ovary Syndrome; Pregnancy; Sex Hormone-Binding Globulin

1980
Clinical, ultrasound and hormonal markers of androgenicity in acne vulgaris.
    The British journal of dermatology, 1995, Volume: 133, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Androgens; Androstenedione; Biomarkers; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Humans; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Ultrasonography

1995
Metabolism of dihydrotestosterone to 5 alpha-androstane-3 alpha, 17 beta-diol glucuronide is greater in the peripheral compartment than in the splanchnic compartment.
    Fertility and sterility, 1995, Volume: 64, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Androstane-3,17-diol; Androsterone; Dihydrotestosterone; Female; Hirsutism; Humans; Infusions, Intravenous; Male; Middle Aged; Polycystic Ovary Syndrome; Prospective Studies; Reference Values; Splanchnic Circulation

1995
Clinical and endocrine effects of laser vaporization in patients with polycystic ovarian disease.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1993, Volume: 7, Issue:1

    Topics: Adult; Androstenedione; Clomiphene; Dihydrotestosterone; Estradiol; Female; Follicular Phase; Humans; Laser Therapy; Luteal Phase; Luteinizing Hormone; Ovulation; Polycystic Ovary Syndrome; Pregnancy; Testosterone

1993
Late endocrine effects of ovarian electrocautery in women with polycystic ovary syndrome.
    Fertility and sterility, 1998, Volume: 69, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Body Weight; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Electrocoagulation; Estradiol; Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Laparoscopy; Longitudinal Studies; Ovulation; Polycystic Ovary Syndrome; Progesterone; Sex Hormone-Binding Globulin; Testosterone; Time Factors

1998
5alpha-reductase activity in women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:7

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Dihydrotestosterone; Female; Gene Expression; Granulosa Cells; Humans; Isoenzymes; Polycystic Ovary Syndrome; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Theca Cells

1999
[Androgens in the plasma of women with hirsutism (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, May-16, Volume: 100, Issue:20

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Androgens; Androstenediols; Carcinoma; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hirsutism; Humans; Leydig Cell Tumor; Middle Aged; Polycystic Ovary Syndrome; Testosterone

1975
Hormone levels following wedge resection in polycystic ovary syndrome.
    Obstetrics and gynecology, 1978, Volume: 51, Issue:1 Suppl

    Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; Luteinizing Hormone; Polycystic Ovary Syndrome; Progesterone; Testosterone

1978
Saliva as a matrix for measuring free androgens: comparison with serum androgens in polycystic ovarian disease.
    Fertility and sterility, 1979, Volume: 31, Issue:5

    Topics: Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Polycystic Ovary Syndrome; Radioimmunoassay; Saliva; Testosterone

1979
[12 cases of polycystic ovary type 1 (Stein-Leventhal syndrome): complete hormonal study (author's transl)].
    Annales d'endocrinologie, 1978, Volume: 39, Issue:3

    Topics: Androstane-3,17-diol; Androstenedione; Clomiphene; Dihydrotestosterone; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Ovary; Polycystic Ovary Syndrome; Pregnancy; Testosterone

1978
Peripheral steroid-gonadotropin interactions and diagnostic significance of double-stimulation tests with luteinizing hormone-releasing hormone in polycystic ovarian disease.
    American journal of obstetrics and gynecology, 1979, Aug-01, Volume: 134, Issue:7

    Topics: Adolescent; Adult; Androgens; Anovulation; Diagnosis, Differential; Dihydrotestosterone; Estradiol; Estrogens; Estrone; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Hirsutism; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Testosterone

1979
The effects of long term testosterone administration on pulsatile luteinizing hormone secretion and on ovarian histology in eugonadal female to male transsexual subjects.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:1

    Topics: Androgens; Dihydrotestosterone; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Ovarian Neoplasms; Ovary; Polycystic Ovary Syndrome; Staining and Labeling; Steroids; Testosterone; Transsexualism

1989
Effect of gonadotrophin-releasing hormone analogue (GnRH-A) administration on serum gonadotrophin and steroid levels in patients with polycystic ovarian disease.
    Acta endocrinologica, 1986, Volume: 111, Issue:2

    Topics: Adult; Androstenedione; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Ovary; Pituitary Gland; Polycystic Ovary Syndrome; Testosterone; Time Factors

1986
Do androgens directly regulate gonadotropin secretion in the polycystic ovary syndrome?
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:1

    Topics: Adult; Androgens; Dihydrotestosterone; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Testosterone

1986
Increased 5 alpha-reductase activity in idiopathic hirsutism.
    Fertility and sterility, 1985, Volume: 43, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstane-3,17-diol; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Genitalia, Female; Hirsutism; Humans; Luteinizing Hormone; Oxidoreductases; Polycystic Ovary Syndrome; Skin; Testosterone

1985
Serum androstanediol glucuronide concentrations in normal and hirsute women and patients with thyroid dysfunction.
    Clinical endocrinology, 1988, Volume: 29, Issue:5

    Topics: Adult; Androstane-3,17-diol; Androstanols; Body Height; Body Weight; Contraceptives, Oral; Dihydrotestosterone; Female; Hirsutism; Humans; Polycystic Ovary Syndrome; Thyroid Diseases

1988
Hyperinsulinemia in hyperthecosis of the ovaries.
    American journal of obstetrics and gynecology, 1986, Volume: 154, Issue:2

    Topics: Androstenedione; Dihydrotestosterone; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Ovarian Diseases; Ovary; Polycystic Ovary Syndrome; Syndrome; Testosterone; Theca Cells; Virilism

1986
Hormonal response to electrocautery of the ovary in patients with polycystic ovarian disease.
    British journal of obstetrics and gynaecology, 1985, Volume: 92, Issue:12

    Topics: Androstenedione; Dihydrotestosterone; Electrocoagulation; Estradiol; Female; Follicle Stimulating Hormone; Hormones; Humans; Luteinizing Hormone; Ovary; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone

1985
Characterization of androgen-binding protein in the human ovarian capsule and its changes by polycystic ovarian disease.
    Gynecologic and obstetric investigation, 1985, Volume: 20, Issue:3

    Topics: Adult; Androgen-Binding Protein; Centrifugation, Density Gradient; Chromatography, Affinity; Dihydrotestosterone; Female; Humans; Middle Aged; Neoplasm Proteins; Ovary; Polycystic Ovary Syndrome

1985
Differential studies on the mechanism of serum androgen and androgen-binding abnormalities in hirsutism.
    American journal of obstetrics and gynecology, 1973, Dec-01, Volume: 117, Issue:7

    Topics: Androgen Antagonists; Androgens; Beta-Globulins; Dihydrotestosterone; Estrogens, Conjugated (USP); Female; Hirsutism; Humans; Menstruation Disturbances; Obesity; Polycystic Ovary Syndrome; Prednisone; Protein Binding; Radioimmunoassay; Testosterone

1973
Dihydrotestosterone in human peripheral plasma.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:4

    Topics: Chromatography, Gel; Dihydrotestosterone; Female; Hirsutism; Humans; Male; Methods; Ovarian Neoplasms; Polycystic Ovary Syndrome; Protein Binding; Testosterone; Tritium

1970