Compounds > dihydrotestosterone
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dihydrotestosterone and Metastase

dihydrotestosterone has been researched along with Metastase in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199012 (37.50)18.7374
1990's7 (21.88)18.2507
2000's7 (21.88)29.6817
2010's4 (12.50)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Alaniz, A; Andò, S; Beyer, AR; Coarfa, C; Du, L; Dustin, D; Edwards, DG; Fernandez, NM; Foulds, CE; Fuqua, SAW; Gao, M; Gelsomino, L; Gonzalez, T; Grimm, SL; Gu, G; Herzog, SK; Hilsenbeck, SG; Huang, HJ; Janku, F; Kim, JA; Kittler, R; Li, S; Liu, D; Lo, HC; Mills, GB; Rechoum, Y; Symmans, WF; Tian, L; Tsimelzon, A; Xu, J; Zhang, XH1
Boers, J; Boersma, HH; de Vries, EFJ; Dorbritz, C; Glaudemans, AWJM; Hospers, GAP; Rikhof, B; Schröder, CP; Venema, CM1
Chen, CL; Chen, WY; Huang, J; Liu, YN; Siu, MK; Tsai, YC; Yeh, HL; Yin, JJ1
Feng, J; Gao, H; Huang, B; Li, L; Li, X; Li, Y; Liu, D; Liu, J; Lu, J; Wang, G; Zhang, L; Zhang, N; Zhang, Y1
Chen, JH; Hsu, YH; Lee, HJ; Liu, Y; Liu, YN1
Coleman, I; Corey, E; Koreckij, TD; Montgomery, RB; Nelson, PS; Nguyen, H; Pitts, TE; Reading, CL; Trauger, RJ; Vessella, RL1
Kyprianou, N; Zhu, ML1
Chen, W; Guo, JM; Sun, LA; Wang, GM; Wang, H1
Nicholson, B; Theodorescu, D1
Batra, SK; Bryan, M; Karan, D; Lin, FC; Lin, MF; Moniaux, N; Ringel, J1
Lih, FB; Mohler, JL; Schell, MJ; Titus, MA; Tomer, KB1
Chang, D; Chiang, A; Lin, SL; Ying, SY1
Beardwell, CG; Bu'Lock, D; Hindley, AC; Ribeiro, GG; Todd, ID; Wilkinson, PM1
Banerjee, CK; Peckham, JC; Sani, BP1
Chinot, O; Desruisseau, S; Ghazarossian-Ragni, E; Martin, PM1
Chang, SM; Chen, BQ; Chung, LW; Kao, C; Pathak, SJ; Sang, QA; Wang, Y; Zhang, H; Zhau, HY1
Albino, AP; Bogenrieder, T; Finstad, CL; Freeman, R; Geng, Y; Magill, C; Nanus, DM; Papandreou, CN; Powell, CT; Reuter, VE; Scheinberg, D; Scher, HI; Usmani, B; Wilk, S1
Khan, MS; O'Brien, A1
Fidler, IJ; Greene, G; Killion, JJ; Pathak, S; Pettaway, CA; Ramirez, E; Wilson, MR1
Bennett, S; Berry, J; Downing, SR; Hill, MA; Joshua, A; Kingsley, EA; Mason, RS; Russell, PJ; Yu, Y1
Iitaka, M; Inaba, M; Katayama, S; Morita, T; Sasano, H; Yamanaka, K1
Chu, TM; Gaeta, JF; Murphy, GP; Saroff, J; Williams, P1
Engel, B; Maass, H; Trams, G1
Bashirelahi, N; Karmi, SA; Powder, JR; Sidh, SM; Young, JD1
Frahm, H; Garbrecht, M; Pompecki, R; Schröder, G1
Everson, LK; Ingle, JN; Krook, JE; Long, HJ; Mailliard, JA; McCormack, GW; Schaid, DJ1
Patsner, B; Piver, MS1
Buzdar, AU; Chu, PS; Hortobagyi, GN1
Albert, JD; Geller, J1
Anbar, D; Glass, AG; Glode, LM; Jagst, CL; Max, DT; Murphy, GP; Smith, JA; Stein, BS; Wettlaufer, JN1
Isaacs, JT1
Beardwell, CG; Bu'lock, D; Hindley, AC; St John, J; Wilkinson, PM1

Reviews

2 review(s) available for dihydrotestosterone and Metastase

ArticleYear
Molecular therapeutics in prostate cancer.
    Histology and histopathology, 2003, Volume: 18, Issue:1

    Topics: Androgens; Apoptosis; Dihydrotestosterone; DNA Methylation; Genetic Therapy; Growth Substances; Humans; Male; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Prostatic Neoplasms; Signal Transduction; Tumor Suppressor Protein p53

2003
Adrenal androgen blockade in relapsed prostate cancer.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:10

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Castration; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Megestrol; Megestrol Acetate; Neoplasm Metastasis; Prognosis; Prostate; Prostatic Neoplasms

1985

Trials

4 trial(s) available for dihydrotestosterone and Metastase

ArticleYear
Serial [
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 144

    Topics: Aged; Androgen Antagonists; Anilides; Breast Neoplasms; Dihydrotestosterone; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Neoplasm Metastasis; Nitriles; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiopharmaceuticals; Receptors, Androgen; Tosyl Compounds

2021
An evaluation of pharmacokinetics and pharmacodynamics of leuprorelin acetate 3M-depot in patients with advanced and metastatic carcinoma of the prostate.
    Urologia internationalis, 1998, Volume: 60, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Carcinoma; Delayed-Action Preparations; Dihydrotestosterone; Evaluation Studies as Topic; Follicle Stimulating Hormone; Humans; Injections, Subcutaneous; Leuprolide; Linear Models; Luteinizing Hormone; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Severity of Illness Index; Statistics, Nonparametric; Testosterone; Treatment Outcome

1998
Trilostane with hydrocortisone in treatment of metastatic breast cancer.
    Breast cancer research and treatment, 1989, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Dihydrotestosterone; Female; Humans; Hydrocortisone; Middle Aged; Nausea; Neoplasm Metastasis; Prospective Studies; Vomiting

1989
Clinical effects of gonadotropin-releasing hormone analogue in metastatic carcinoma of prostate.
    Urology, 1985, Volume: 25, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Castration; Clinical Trials as Topic; Diethylstilbestrol; Dihydrotestosterone; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hormones; Humans; Leuprolide; Luteinizing Hormone; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Testosterone

1985

Other Studies

26 other study(ies) available for dihydrotestosterone and Metastase

ArticleYear
Hormonal modulation of ESR1 mutant metastasis.
    Oncogene, 2021, Volume: 40, Issue:5

    Topics: Animals; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mutation; Neoplasm Metastasis; Receptors, Androgen; Tamoxifen; Xenograft Model Antitumor Assays

2021
Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis.
    Oncogene, 2017, 11-09, Volume: 36, Issue:45

    Topics: Androgen Receptor Antagonists; Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Down-Regulation; Heterografts; Humans; Male; Mice; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Transfection

2017
Androgen and AR contribute to breast cancer development and metastasis: an insight of mechanisms.
    Oncogene, 2017, 05-18, Volume: 36, Issue:20

    Topics: Androgens; Animals; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Gene Knockdown Techniques; Histone Demethylases; Humans; Mice; Neoplasm Metastasis; Prognosis; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Vimentin; Xenograft Model Antitumor Assays

2017
Activated androgen receptor downregulates E-cadherin gene expression and promotes tumor metastasis.
    Molecular and cellular biology, 2008, Volume: 28, Issue:23

    Topics: Animals; Cadherins; Carcinoma, Ductal, Breast; Cell Line, Tumor; Dihydrotestosterone; Down-Regulation; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Mesenchymal Stem Cells; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Experimental; Promoter Regions, Genetic; Protein Binding; Receptors, Androgen; Transplantation, Heterologous; Tumor Cells, Cultured

2008
HE3235 inhibits growth of castration-resistant prostate cancer.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:11

    Topics: Androstanols; Animals; Antineoplastic Agents; Bone Neoplasms; Castration; Dihydrotestosterone; Gene Expression; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasm Metastasis; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Xenograft Model Antitumor Assays

2009
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:3

    Topics: Androgen Receptor Antagonists; Blotting, Western; Cell Dedifferentiation; Cell Line, Tumor; Cell Movement; Dihydrotestosterone; Epithelial Cells; Flow Cytometry; Humans; Male; Mesoderm; Neoplasm Metastasis; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta

2010
NGF/γ-IFN inhibits androgen-independent prostate cancer and reverses androgen receptor function through downregulation of FGFR2 and decrease in cancer stem cells.
    Stem cells and development, 2012, Dec-10, Volume: 21, Issue:18

    Topics: Animals; Apoptosis; Cell Count; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Down-Regulation; Humans; Interferon-gamma; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Nerve Growth Factor; Prostatic Neoplasms; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Androgen; Transplantation, Heterologous; Wnt1 Protein; Wnt2 Protein

2012
Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.
    International journal of oncology, 2003, Volume: 23, Issue:5

    Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Adenocarcinoma; Amyloid Precursor Protein Secretases; Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Line, Tumor; Dihydrotestosterone; Disintegrins; Humans; Male; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3; Tissue Inhibitor of Metalloproteinases; Up-Regulation

2003
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jul-01, Volume: 11, Issue:13

    Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Dihydrotestosterone; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prostatic Neoplasms; Radioimmunoassay; Spectrometry, Mass, Electrospray Ionization; Survival Analysis; Testosterone

2005
Androgen receptor regulates CD168 expression and signaling in prostate cancer.
    Carcinogenesis, 2008, Volume: 29, Issue:2

    Topics: Animals; Bone Marrow Cells; Cell Line, Tumor; Dihydrotestosterone; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Male; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction

2008
Trilostane in the treatment of advanced breast cancer.
    Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis

1983
The presence of binding proteins for retinoic acid and dihydrotestosterone in murine and human colon tumors.
    Cancer, 1980, Dec-01, Volume: 46, Issue:11

    Topics: Adenocarcinoma; Animals; Brain Chemistry; Carcinoma; Carrier Proteins; Centrifugation, Density Gradient; Colonic Neoplasms; Dihydrotestosterone; Humans; Lung; Male; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasms, Experimental; Tretinoin

1980
Divergent effect of TGFbeta1 on growth and proteolytic modulation of human prostatic-cancer cell lines.
    International journal of cancer, 1996, Jun-11, Volume: 66, Issue:6

    Topics: Bone Marrow; Brain Neoplasms; Carcinoma; Cell Division; Culture Media; Dihydrotestosterone; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Metastasis; Neoplasm Proteins; Plasminogen Activator Inhibitor 1; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1996
Androgen-repressed phenotype in human prostate cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Dec-24, Volume: 93, Issue:26

    Topics: Aged; Aged, 80 and over; Androgens; Animals; Ascites; Cell Division; Cell Line; Dihydrotestosterone; Estradiol; Estrogens; Genetic Markers; Humans; Karyotyping; Lymphatic Metastasis; Male; Mice; Mice, Nude; Mutagenesis, Site-Directed; Neoplasm Metastasis; Phenotype; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Transplantation, Heterologous; Tumor Cells, Cultured

1996
Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression.
    Nature medicine, 1998, Volume: 4, Issue:1

    Topics: Biomarkers, Tumor; Biopsy; Cell Division; Cell Nucleus; Dihydrotestosterone; Disease Progression; Gene Transfer Techniques; Humans; Kinetics; Male; Neoplasm Metastasis; Neprilysin; Polymerase Chain Reaction; Prostatic Neoplasms; Recombinant Proteins; Tetracycline; Time Factors; Transfection; Tumor Cells, Cultured

1998
Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:9

    Topics: Animals; Bone Neoplasms; Cell Division; Culture Media; Dihydrotestosterone; Genetic Variation; Humans; Karyotyping; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Tumor Cells, Cultured

1996
Elevated expression of FGF-2 does not cause prostate cancer progression in LNCaP cells.
    The Prostate, 1999, Jun-15, Volume: 40, Issue:1

    Topics: Animals; Cell Division; Dihydrotestosterone; Disease Progression; Female; Fibroblast Growth Factor 2; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prostatic Neoplasms; Testosterone; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured

1999
A case of renin-producing adrenocortical cancer.
    Endocrine journal, 2000, Volume: 47, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Biopsy, Needle; Catecholamines; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Enzyme Inhibitors; Female; Glucocorticoids; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hypertension; Hypokalemia; Middle Aged; Mitotane; Muscle Weakness; Neoplasm Metastasis; Renin; Thirst; Tomography, X-Ray Computed

2000
Characterization of a Wilms' tumor model.
    Investigative urology, 1975, Volume: 12, Issue:4

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Kidney; Kidney Neoplasms; Male; Muscles; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Peritoneal Cavity; Rats; Sex Factors; Testosterone; Tissue Survival; Transplantation, Homologous; Wilms Tumor

1975
Steroid hormone receptors in human breast cancer and the clinical significance.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: Breast Neoplasms; Castration; Cytoplasm; Dihydrotestosterone; Estradiol; Female; Humans; Hypophysectomy; Menopause; Neoplasm Metastasis; Receptors, Cell Surface

1975
Adenocarcinoma of prostate: role of 17beta-estradiol and 5alpha-dihydrotestosterone binding proteins.
    Urology, 1979, Volume: 13, Issue:6

    Topics: Adenocarcinoma; Castration; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid

1979
[Carcinoembryonic antigens (CEA) in patients with metastatic breast cancer under endocrine and therapeutic treatment (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Apr-07, Volume: 103, Issue:14

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoembryonic Antigen; Castration; Dihydrotestosterone; Ethinyl Estradiol; Female; Humans; Neoplasm Metastasis; Progesterone; Remission, Spontaneous; Tamoxifen

1978
Evaluation of trilostane plus hydrocortisone in women with metastatic breast cancer and prior hormonal therapy exposure.
    American journal of clinical oncology, 1990, Volume: 13, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dihydrotestosterone; Female; Hormones; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Remission Induction

1990
Treatment of metastatic lipid cell tumor of the ovary with BV-CAP and VAC chemotherapy, using serum testosterone and dihydrotestosterone as tumor markers.
    European journal of gynaecological oncology, 1988, Volume: 9, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Cyclophosphamide; Dactinomycin; Dihydrotestosterone; Doxorubicin; Female; Humans; Lipoma; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Testosterone; Vincristine

1988
New principles in the management of metastatic prostatic cancer.
    Progress in clinical and biological research, 1985, Volume: 185A

    Topics: Animals; Castration; Combined Modality Therapy; Cyclophosphamide; Cyproterone; Dihydrotestosterone; Male; Neoplasm Metastasis; Prostatic Neoplasms; Rats; Testosterone

1985
Hormonal changes in postmenopausal women with breast cancer treated with trilostane and dexamethasone.
    Clinical endocrinology, 1985, Volume: 23, Issue:4

    Topics: Adrenal Cortex Hormones; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estrone; Female; Gonadal Steroid Hormones; Humans; Menopause; Neoplasm Metastasis

1985