Page last updated: 2024-08-21

dihydrotestosterone and Hypergonadotropic Hypogonadism

dihydrotestosterone has been researched along with Hypergonadotropic Hypogonadism in 111 studies

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-199039 (35.14)18.7374
1990's21 (18.92)18.2507
2000's27 (24.32)29.6817
2010's18 (16.22)24.3611
2020's6 (5.41)2.80

Authors

AuthorsStudies
Chang, W; Kallel, A; López, FJ; Marschke, KB; Martinborough, E; Motamedi, M; Negro-Vilar, A; Shen, Y; van Oeveren, A; West, S; Zhao, S; Zhi, L1
Chang, WY; Lau, TL; Long, YO; López, FJ; Marschke, KB; Martinborough, E; Negro-Vilar, A; Oeveren, Av; Rix, PJ; Shen, Y; Vajda, EG; Viveros, OH; Zhi, L1
Bracken, K; Conway, AJ; Desai, R; Grossmann, M; Handelsman, DJ; Inder, WJ; Jesudason, D; Ly, LP; Shankara-Narayana, N; Stuckey, BGA; Wittert, GA; Yeap, BB1
Aguilar-Riera, C; Camats-Tarruella, N; Canestrino, G; Clemente, M; Fernández-Alvarez, P; Yeste, D1
Carmeliet, G; Claessens, F; D'Haese, P; David, K; Deboel, L; Decallonne, B; Dubois, V; Evenepoel, P; Moermans, K; Schollaert, D; Sommers, V; Vanderschueren, D; Verhulst, A1
Gittelman, M; Jaffe, JS; Kaminetsky, JC1
Baccini, M; Bartolomeo, N; Carbone, MD; De Pergola, G; Di Dalmazi, G; Fanelli, F; Giagulli, VA; Pagotto, U; Pasquali, R; Pelusi, C; Triggiani, V1
Antonio, L; Claessens, F; Corbeels, K; David, K; Deboel, L; Decallonne, B; Dubois, V; Gustafsson, JÅ; Khalil, R; Kim, NR; Ohlsson, C; Schollaert, D; Van der Schueren, B; Vanderschueren, D; Vangoitsenhoven, R1
Dugas, M; Isidori, AM; Kliesch, S; Sandhowe-Klaverkamp, R; Sansone, A; Schlatt, S; Zitzmann, M1
Cohen, B; McMahon, CG; Shusterman, N1
Conway, A; Curtis, D; Goebel, C; Handelsman, DJ; Jayadev, V; Lim, S; Savkovic, S; Turner, L1
Ascoli, M; Matzkin, ME; Yamashita, S1
Corbo, GM; Di Marco Berardino, A; Inchingolo, R; Mancini, A; Raimondo, S; Smargiassi, A; Valente, S1
Brailly-Tabard, S; Fiet, J; Giton, F; Le Bouc, Y; Maione, L; Sarfati, J; Trabado, S; Young, J1
De Toni, L; Di Nisio, A; Ferlin, A; Foresta, C; Rocca, MS; Speltra, E; Taglialavoro, G1
Carrara, D; Efros, M; Neijber, A1
Buckley, MJ; Harrison, RW; Wittert, GA; Wlodarczyk, J1
Gleeson, HK; Shalet, SM1
Gooren, LJ; Haide, A; Saad, F; Yassin, A1
Boonen, S; Bouillon, R; Callewaert, F; Ophoff, J; Vanderschueren, D; Venken, K1
Abel, MH; De Gendt, K; Monteiro, A; O'Shaughnessy, PJ; Verhoeven, G1
Barrett-Connor, E; Bergstrom, J; Lakin, C; Palazzi-Churas, K; Parsons, JK; Trifiro, MD1
Friedman, AE1
Araujo, AB; Wittert, GA1
Baron, S; Brailly-Tabard, S; Bry-Gauillard, H; Chanson, P; Galland, F; Guiochon-Mantel, A; Maione, L; Pitteloud, N; Salenave, S; Sinisi, AA; Trabado, S; Young, J1
Goldenberg, SL; Koupparis, A; Robinson, ME1
Blankenstein, MA; Bui, HN; Heijboer, AC; Meuleman, EJ; van der Sluis, TM; van Moorselaar, RJ; Vis, AN1
Bartfai, G; Boonen, S; Bouillon, R; Casanueva, FF; Finn, JD; Forti, G; Giwercman, A; Han, TS; Huhtaniemi, IT; Kula, K; Lean, ME; Lee, DM; O'Neill, TW; Pendleton, N; Punab, M; Pye, SR; Tajar, A; Vanderschueren, D; Wu, FC1
Allan, CM; Foo, CF; McCabe, MJ; McTavish, KJ; Nicholls, PK; Stanton, PG1
Arai, S; Hashimoto, K; Honma, S; Ito, K; Kashiwagi, B; Miyashiro, Y; Nakamura, Y; Sasano, H; Sekine, Y; Shibata, Y; Suzuki, K; Tomaru, Y; Uei, T1
Adams, BD; Callaghan, JJ; Handa, RJ; Hendrix, MJ; Khalkhali-Ellis, Z; Price, RH1
Bullmann, C; Jockenhövel, F; Krone, W; Minnemann, T; Reiners, C; Schubert, M1
Bélanger, A; Bélanger, MC; Julien, P; Labrie, C; Labrie, F; Leblanc, M; Tchernof, A1
Bouloux, PM; Cullen, D; Grossman, AB; Korbonits, M; Reincke, M; Ross, RJ; Schneider, H; Slawik, M; Stalla, G1
Cunningham, G; Dobs, AS; Friedman, TC; Katznelson, L; Kipnes, M; Levine, HL; Matsumoto, AM; Snyder, P; Swerdloff, R; Wang, C; Weber, TJ1
Nowotny, P; Vierhapper, H; Waldhäusl, W1
Byrne, M; Gerss, J; Köpcke, W; Kühnert, B; Lemmnitz, G; Nieschlag, E; Simoni, M1
Qoubaitary, A; Swerdloff, RS; Wang, C1
Brennan, K; Handelsman, DJ; Seibel, MJ; Sims, NA; Spaliviero, J1
Bell, D; Cosgrove, M; Eilers, B; Fischer, J; Mazer, N; Wu, J1
Berlin, K; Bloch, M; Kevala, KR; Kim, HY; Rubinow, DR; Schmidt, PJ1
Bostwick, DG; Dorey, FJ; Epstein, JI; Hess, DL; Macairan, ML; Makarov, DV; Marks, LS; Mazer, NA; Mostaghel, E; Nelson, PS; Partin, AW; Veltri, RW1
Saad, F; Yassin, AA1
Augès, M; Bunouf, P; Fiet, J; Legros, JJ; Raynaud, JP; Rollet, J; Sournac, M1
Licea-Perez, H; Szapacs, ME; Wang, S; Yang, E1
Gibson, C; Haq, N; Negro, PP; Rubinow, DR; Schmidt, PJ; Steinberg, EM1
Lagoguey, M; Mowszowicz, I; Renoir, M; Schaison, G1
Duckett, GE; Reiter, EO; Root, AW1
Anderson, DC; Cantrill, JA; Dewis, P; Large, DM; Newman, M1
Deucher, R; Fukushima, DK; Kream, J; Levin, J; Rosenfeld, RS; Strain, GW; Strain, JJ; Zumoff, B1
Davidson, JM; Greenleaf, WJ; Kwan, M1
Bancroft, J; Davidson, DW; Skakkebaek, NE; Warner, P1
Joplin, GF; Kelly, WF; Kjeld, JM; Mashiter, K1
Brerault, JL; Chemana, D; Fiet, J; Morville, R; Passa, P; Tabuteau, F; Villette, JM1
Dash, RJ; Lamba, PS; Sialy, R1
Cain, MP; Husmann, DA1
Crawford, BA; Handelsman, DJ; Simpson, JM; Singh, J1
Alexander, G; Berman, N; Davidson, T; Dudley, RE; McDonald, V; Salehian, B; Swerdloff, RS; Wang, C; Ziel, F1
Arver, S; Dobs, AS; Mazer, NA; Meikle, AW; Rajaram, L; Sanders, SW1
Jockenhövel, F; Kreutzer, M; Lederbogen, S; Reinhardt, W; Reinwein, D; Vogel, E1
Alexander, G; Barstow, TJ; Berman, N; Clark, R; Davidson, T; Dudley, RE; Eyre, DR; Iranmanesh, A; Kleinberg, D; Newman, C; Sinow, R; Swerdloff, RS; Veldhuis, J; Wang, C1
Jockenhövel, F; Reinhardt, W; Reinwein, D; Vogel, E1
Blum, WF; Englaro, P; Jockenhövel, F; Krone, W; Müller-Wieland, D; Rascher, W; Reinwein, D; Vogel, E1
Castro, R; Legon, C; Li, GR; Ludot, T; Tostain, J1
Atkinson, L; Winters, SJ1
Allen, R; Chen, MC; Dobs, AS; Hoover, DR1
Arver, S; Caramelli, KE; Dobs, AS; Mazer, NA; Meikle, AW; Rajaram, L; Sanders, SW1
Behre, HM; Dressendörfer, RA; Nieschlag, E; Strasburger, CJ; Tschöp, M1
Swerdloff, RS; Wang, C1
Behre, HM; Kliesch, S; Nieschlag, E; von Eckardstein, S1
Abshagen, K; Behre, HM; Büchter, D; Nieschlag, E; Simoni, M; Von Eckardstein, S1
Kung, AW; Shiu, SW; Tan, KC1
Berman, N; Chuapoco, B; Dudley, RE; Faulkner, S; Hull, L; Longstreth, JA; Steiner, B; Swerdloff, RS; Wang, C1
Asscheman, H; Gooren, LJ1
Berman, N; Cunningham, G; Dobs, A; Iranmanesh, A; Longstreth, J; Matsumoto, AM; Snyder, PJ; Swerdloff, RS; Wang, C; Weber, T1
Arver, S; Bachorik, PS; Caramelli, KE; Dobs, AS; Mazer, NA; Meikle, AW; Sanders, SW1
Clark, JC; Daniell, HW; Dunn, SR; Ferguson, DW; Figueroa, ML; Niazi, ZA; Pereira, SE; Stratte, PT1
Franchimont, P; Kicovic, PM; Mattei, A; Roulier, R1
Stahl, F1
Caminos-Torres, R; Ma, L; Snyder, PJ1
Loriaux, DL; Sherins, RJ; Winters, SJ1
Leone, G; Petrosino, L1
Bundschu, HD; Hayduk, K; Heller, S; Liebau, G; Lüders, G; Pfeiffer, EH; Rager, K1
Abbasi, AA; Congco, E; Oberleas, D; Ortega, J; Prasad, AS1
Vermeulen, A1
Hosaka, M1
Arimura, A; Kastin, AJ; Schally, AV1
Coert, A; Hirschhäuser, C; Hopkinson, CR; Sturm, G1
Bricaire, H; Mahoudeau, JA; Valcke, JC1
Kuttenn, F; Mauvais-Jarvis, P1
Cappellini, A; Forti, G; Pazzagli, M; Serio, M1
Bricaire, H; Mahoudeau, JA1
Mazer, NA; Meikle, AW; Moellmer, JF; Odell, WD; Sanders, SW; Stringham, JD; Tolman, KG1
Dudley, RE; Stuenkel, CA; Yen, SS1
Cunningham, GR; Hirshkowitz, M; Karacan, I; Korenman, SG1
Findlay, JC; Place, V; Snyder, PJ1
Cordero, E; Cunningham, GR; Thornby, JI1
Adler, RA; Deiss, WP; Farrell, ME; Krieg, RJ1
Díaz-Sánchez, V; Garza-Flores, J; Larrea, F; Richards, E; Ulloa-Aguirre, A; Veayra, F1
Bals-Pratsch, M; Langer, K; Nieschlag, E; Place, VA1
Ahmed, SR; Bartholomew, M; Boucher, AE; Demers, LM; Manni, A; Santen, RJ1
Burris, AS; Ewing, LL; Sherins, RJ1
Gooren, LJ1
Niermann, H; Schulz, H1
Besser, GM; Fisher, RA; McNeilly, AS; Mortimer, CH; Murray, MA1
Barnes, EW; Irvine, WJ; Ismail, AA1
Concolino, G; Marocchi, A; Sciarra, F; Sorcini, G1
Gold, NI; Jan, W1
Bercovici, JP; Crepy, Q; Mauvais-Jarvis, P1
Hamilton, CR; Kliman, B1
Bercovici, JP; Floch, HH; Mauvais-Jarvis, P1

Reviews

7 review(s) available for dihydrotestosterone and Hypergonadotropic Hypogonadism

ArticleYear
Endocrinology of the aging male.
    Best practice & research. Clinical endocrinology & metabolism, 2011, Volume: 25, Issue:2

    Topics: Aging; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Sex Hormone-Binding Globulin; Testis; Testosterone

2011
Differing levels of testosterone and the prostate: a physiological interplay.
    Nature reviews. Urology, 2011, May-31, Volume: 8, Issue:7

    Topics: Animals; Dihydrotestosterone; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Prostate; Prostatic Neoplasms; Testosterone

2011
Intraprostatic testosterone and dihydrotestosterone. Part II: concentrations after androgen hormonal manipulation in men with benign prostatic hyperplasia and prostate cancer.
    BJU international, 2012, Volume: 109, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adult; Androgen Antagonists; Contraindications; Dihydrotestosterone; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone

2012
Advances in male hormone substitution therapy.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:9

    Topics: Age Factors; Androgen Receptor Antagonists; Androgens; Clinical Trials as Topic; Contraindications; Dihydrotestosterone; Drug Delivery Systems; Drug Monitoring; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Testosterone

2005
[Treatment of erectile disorders with androgens: When? How?].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1997, Volume: 7, Issue:2

    Topics: Algorithms; Decision Trees; Dihydrotestosterone; Drug Monitoring; Erectile Dysfunction; Humans; Hypogonadism; Male; Patient Selection; Testosterone

1997
Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent.
    Bailliere's clinical endocrinology and metabolism, 1998, Volume: 12, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Aging; Dihydrotestosterone; Gels; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Middle Aged

1998
[The determination, secretion and plasma concentration of androgens].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Oct-15, Volume: 34, Issue:20

    Topics: Adolescent; Adult; Age Factors; Androgen Antagonists; Androgen-Binding Protein; Androgens; Androstane-3,17-diol; Androstenedione; Child; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Hypogonadism; Infant; Male; Pregnancy; Radioimmunoassay; Sex Factors; Testosterone; Virilism

1979

Trials

34 trial(s) available for dihydrotestosterone and Hypergonadotropic Hypogonadism

ArticleYear
Recovery of male reproductive endocrine function after ceasing prolonged testosterone undecanoate injections.
    European journal of endocrinology, 2022, Jan-28, Volume: 186, Issue:3

    Topics: Aged; Cohort Studies; Diabetes Mellitus, Type 2; Dihydrotestosterone; Follicle Stimulating Hormone; Follow-Up Studies; Genitalia, Male; Glucose Intolerance; Humans; Hypogonadism; Injections; Luteinizing Hormone; Male; Middle Aged; Quality of Life; Recovery of Function; Sexual Behavior; Testosterone; Withholding Treatment

2022
Safety of a New Subcutaneous Testosterone Enanthate Auto-Injector: Results of a 26-Week Study.
    The journal of sexual medicine, 2019, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Aged; Blood Pressure Monitoring, Ambulatory; Dihydrotestosterone; Estradiol; Hormone Replacement Therapy; Humans; Hypogonadism; Injections; Male; Middle Aged; Prostate-Specific Antigen; Reproducibility of Results; Testosterone; Young Adult

2019
Effect of clomiphene citrate treatment on the Sertoli cells of dysmetabolic obese men with low testosterone levels.
    Clinical endocrinology, 2020, Volume: 92, Issue:1

    Topics: Adult; Anti-Mullerian Hormone; Clomiphene; Cross-Over Studies; Diabetes Mellitus, Type 2; Dihydrotestosterone; Double-Blind Method; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Follow-Up Studies; Humans; Hypoglycemic Agents; Hypogonadism; Inhibins; Male; Metabolic Syndrome; Metformin; Middle Aged; Obesity; Sertoli Cells; Testosterone

2020
Pharmacokinetics, Clinical Efficacy, Safety Profile, and Patient-Reported Outcomes in Patients Receiving Subcutaneous Testosterone Pellets 900 mg for Treatment of Symptoms Associated With Androgen Deficiency.
    The journal of sexual medicine, 2017, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Aged; Dihydrotestosterone; Drug Implants; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Patient Reported Outcome Measures; Patient Satisfaction; Penile Erection; Prospective Studies; Surveys and Questionnaires; Testosterone; Treatment Outcome; Young Adult

2017
The efficacy, bioavailability and safety of a novel hydroalcoholic testosterone gel 2% in hypogonadal men: results from phase II open-label studies.
    Andrologia, 2016, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Biological Availability; Dihydrotestosterone; Gels; Humans; Hypogonadism; Male; Middle Aged; Testosterone; Treatment Outcome; Young Adult

2016
An open-label, phase 2, single centre, randomized, crossover design bioequivalence study of AndroForte 5 testosterone cream and Testogel 1% testosterone gel in hypogonadal men: study LP101.
    Andrology, 2016, Volume: 4, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Androgens; Cross-Over Studies; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Gels; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Sex Hormone-Binding Globulin; Skin Cream; Testosterone; Therapeutic Equivalency

2016
Effect of aromatizable and unaromatizable androgen replacement in hypogonadal men on GH responsiveness.
    Clinical endocrinology, 2009, Volume: 70, Issue:1

    Topics: Adult; Androgens; Dihydrotestosterone; Hormone Replacement Therapy; Human Growth Hormone; Humans; Hypogonadism; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Middle Aged; Recombinant Proteins; Testosterone

2009
Decline of plasma 5alpha-dihydrotestosterone (DHT) levels upon testosterone administration to elderly men with subnormal plasma testosterone and high DHT levels.
    Andrologia, 2008, Volume: 40, Issue:5

    Topics: Aging; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Humans; Hypogonadism; Male; Middle Aged; Testosterone

2008
Osteoporosis in male hypogonadism: responses to androgen substitution differ among men with primary and secondary hypogonadism.
    Hormone research, 2003, Volume: 60, Issue:1

    Topics: Adult; Aged; Androgens; Bone Density; Dihydrotestosterone; Double-Blind Method; Drug Implants; Estradiol; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Mesterolone; Middle Aged; Osteoporosis; Prospective Studies; Steroids; Testosterone

2003
A comparison of a novel testosterone bioadhesive buccal system, striant, with a testosterone adhesive patch in hypogonadal males.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:5

    Topics: Administration, Buccal; Adult; Androgens; Dihydrotestosterone; Drug Delivery Systems; Humans; Hypogonadism; Male; Middle Aged; Osmolar Concentration; Testosterone; Tissue Adhesives

2004
New testosterone buccal system (Striant) delivers physiological testosterone levels: pharmacokinetics study in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:8

    Topics: Adult; Aged; Aging; Androgens; Body Mass Index; Cheek; Dihydrotestosterone; Drug Administration Schedule; Drug Delivery Systems; Estradiol; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Mouth Mucosa; Osmolar Concentration; Patient Acceptance of Health Care; Patient Compliance; Testosterone; Tissue Adhesives

2004
Production rates of cortisol in men with hypogonadism.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:9

    Topics: Adult; Aging; Body Mass Index; Chromatography, High Pressure Liquid; Dihydrotestosterone; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Hypogonadism; Kinetics; Male; Middle Aged; Testosterone

2004
Testosterone substitution with a new transdermal, hydroalcoholic gel applied to scrotal or non-scrotal skin: a multicentre trial.
    European journal of endocrinology, 2005, Volume: 153, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Androgens; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Gels; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Patient Dropouts; Prostate; Prostate-Specific Antigen; Scrotum; Surveys and Questionnaires; Testosterone

2005
Comparison of the steady-state pharmacokinetics, metabolism, and variability of a transdermal testosterone patch versus a transdermal testosterone gel in hypogonadal men.
    The journal of sexual medicine, 2005, Volume: 2, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Androgens; Cross-Over Studies; Dihydrotestosterone; Estradiol; Gels; Humans; Hypogonadism; Male; Middle Aged; Testosterone; Therapeutic Equivalency

2005
Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial.
    JAMA, 2006, Nov-15, Volume: 296, Issue:19

    Topics: Adult; Age of Onset; Aged; Biopsy, Needle; Dihydrotestosterone; Double-Blind Method; Epithelial Cells; Gene Expression Profiling; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; RNA; Testosterone

2006
Plasma levels of dihydrotestosterone remain in the normal range in men treated with long-acting parenteral testosterone undecanoate.
    Andrologia, 2007, Volume: 39, Issue:5

    Topics: Aged; Azasteroids; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Drug Therapy, Combination; Dutasteride; Enzyme Inhibitors; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Testosterone

2007
Efficacy and safety of a new testosterone-in-adhesive matrix patch applied every 2 days for 1 year to hypogonadal men.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 109, Issue:1-2

    Topics: Adhesiveness; Adhesives; Administration, Cutaneous; Adolescent; Adult; Aged; Androstenedione; Biological Availability; Delayed-Action Preparations; Dihydrotestosterone; Drug Administration Schedule; Drug Delivery Systems; Drug Tolerance; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Prostate-Specific Antigen; Safety; Testosterone; Time Factors

2008
Pharmacologically induced hypogonadism and sexual function in healthy young women and men.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:3

    Topics: Adult; Affect; Dihydrotestosterone; Estradiol; Female; Humans; Hypogonadism; Leuprolide; Male; Middle Aged; Orgasm; Progesterone; Sex Characteristics; Sexual Behavior; Sexual Dysfunction, Physiological; Testosterone

2009
Androgen replacement with oral testosterone undecanoate in hypogonadal men: a double blind controlled study.
    Clinical endocrinology, 1981, Volume: 14, Issue:1

    Topics: Adult; Clinical Trials as Topic; Dihydrotestosterone; Double-Blind Method; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Sex Hormone-Binding Globulin; Sexual Behavior; Testosterone

1981
Pharmacokinetics and metabolism of a permeation-enhanced testosterone transdermal system in hypogonadal men: influence of application site- -a clinical research center study.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Biological Availability; Cross-Over Studies; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Humans; Hypogonadism; Kinetics; Luteinizing Hormone; Male; Metabolic Clearance Rate; Middle Aged; Testosterone

1996
Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10

    Topics: Administration, Sublingual; Adult; Anthropometry; Body Composition; Bone Remodeling; Bone Resorption; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Muscles; Progesterone; Sex; Testosterone

1996
Effects of various modes of androgen substitution therapy on erythropoiesis.
    European journal of medical research, 1997, Jul-28, Volume: 2, Issue:7

    Topics: Adult; Dihydrotestosterone; Drug Implants; Erythropoiesis; Ferritins; Hematocrit; Hemoglobins; Humans; Hypogonadism; Iron; Male; Mesterolone; Regression Analysis; Testosterone; Testosterone Congeners

1997
Testosterone substitution normalizes elevated serum leptin levels in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:8

    Topics: Adult; Body Mass Index; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Leptin; Male; Proteins; Regression Analysis; Sex Hormone-Binding Globulin; Testosterone

1997
Pharmacokinetic characteristics, efficacy, and safety of buccal testosterone in hypogonadal males: a pilot study.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:1

    Topics: Administration, Buccal; Adult; Aged; Dihydrotestosterone; Double-Blind Method; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Pilot Projects; Placebos; Sex Hormone-Binding Globulin; Testosterone; Time Factors

1998
Long-term efficacy and safety of a permeation-enhanced testosterone transdermal system in hypogonadal men.
    Clinical endocrinology, 1997, Volume: 47, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Dermatitis, Contact; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Testosterone

1997
A time-resolved fluorescence immunoassay for the measurement of testosterone in saliva: monitoring of testosterone replacement therapy with testosterone buciclate.
    Clinical chemistry and laboratory medicine, 1998, Volume: 36, Issue:4

    Topics: Adult; Dihydrotestosterone; Estradiol; Female; Fluoroimmunoassay; Humans; Hypogonadism; Male; Middle Aged; Radioimmunoassay; Saliva; Sensitivity and Specificity; Sex Hormone-Binding Globulin; Testosterone

1998
Repeated intramuscular injections of testosterone undecanoate for substitution therapy in hypogonadal men.
    Clinical endocrinology, 1999, Volume: 51, Issue:6

    Topics: Adult; Analysis of Variance; Body Weight; Dihydrotestosterone; Ejaculation; Estradiol; Hormone Replacement Therapy; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone

1999
Pharmacokinetics of transdermal testosterone gel in hypogonadal men: application of gel at one site versus four sites: a General Clinical Research Center Study.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:3

    Topics: Administration, Cutaneous; Adult; Cross-Over Studies; Dihydrotestosterone; Estradiol; Female; Gels; Hormone Replacement Therapy; Humans; Hypogonadism; Middle Aged; Testosterone

2000
[Scrotal testosterone patches: a good addition to therapeutic options for hypogonadal men].
    Nederlands tijdschrift voor geneeskunde, 2000, Apr-29, Volume: 144, Issue:18

    Topics: Administration, Cutaneous; Adult; Dihydrotestosterone; Follow-Up Studies; Hormone Replacement Therapy; Humans; Hypogonadism; Libido; Male; Middle Aged; Patient Dropouts; Scrotum; Sex; Testosterone; Treatment Outcome

2000
Long-term pharmacokinetics of transdermal testosterone gel in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Biological Availability; Dihydrotestosterone; Estradiol; Gels; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Patient Compliance; Sex Hormone-Binding Globulin; Testosterone

2000
Interrelationships among lipoprotein levels, sex hormones, anthropometric parameters, and age in hypogonadal men treated for 1 year with a permeation-enhanced testosterone transdermal system.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aging; Anthropometry; Cholesterol; Dihydrotestosterone; Estradiol; Gonadal Steroid Hormones; Humans; Hypogonadism; Lipoproteins; Lipoproteins, HDL; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone

2001
[Depot mesterolone in the management of male hypogonadism].
    La Clinica terapeutica, 1976, Nov-15, Volume: 79, Issue:3

    Topics: Clinical Trials as Topic; Delayed-Action Preparations; Dihydrotestosterone; Drug Evaluation; Humans; Hypogonadism; Male; Mesterolone

1976
Testosterone undecanoate: a new orally active androgen.
    Acta endocrinologica, 1975, Volume: 80, Issue:1

    Topics: 17-Ketosteroids; Administration, Oral; Adult; Androgens; Clinical Trials as Topic; Dihydrotestosterone; Fatty Acids; Humans; Hypogonadism; Male; Placebos; Stimulation, Chemical; Testosterone

1975
Substitution therapy of hypogonadal men with transdermal testosterone over one year.
    Acta endocrinologica, 1988, Volume: 118, Issue:1

    Topics: Administration, Cutaneous; Adult; Clinical Trials as Topic; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Scrotum; Testosterone; Time Factors

1988

Other Studies

70 other study(ies) available for dihydrotestosterone and Hypergonadotropic Hypogonadism

ArticleYear
Novel selective androgen receptor modulators: SAR studies on 6-bisalkylamino-2-quinolinones.
    Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Binding, Competitive; Dihydrotestosterone; Genitalia, Male; Hypogonadism; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Conformation; Orchiectomy; Organ Size; Organ Specificity; Prostate; Quinolines; Rats; Receptors, Androgen; Structure-Activity Relationship; Transfection

2007
Substituted 6-(1-pyrrolidine)quinolin-2(1H)-ones as novel selective androgen receptor modulators.
    Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21

    Topics: Administration, Oral; Anabolic Agents; Androgen Receptor Antagonists; Androgens; Animals; Biological Availability; Bone Density Conservation Agents; Female; Humans; Hypogonadism; Male; Muscle, Skeletal; Organ Size; Osteoporosis, Postmenopausal; Prostate; Pyrrolidines; Quinolines; Quinolones; Rats; Stereoisomerism; Structure-Activity Relationship

2007
A New
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Dihydrotestosterone; DNA-Binding Proteins; Humans; Hypogonadism; Hypospadias; Luteinizing Hormone; Male; Nuclear Proteins; Testis; Testosterone; Transcription Factors

2022
Androgen therapy does not prevent bone loss and arterial calcifications in male rats with chronic kidney disease.
    The Journal of endocrinology, 2023, 06-01, Volume: 257, Issue:3

    Topics: Adenine; Androgens; Animals; Bone Diseases, Metabolic; Dihydrotestosterone; Hypogonadism; Male; Rats; Renal Insufficiency, Chronic; Testosterone

2023
Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling.
    Endocrinology, 2021, 06-01, Volume: 162, Issue:6

    Topics: Adipose Tissue; Animals; Dihydrotestosterone; Energy Metabolism; Estrogen Receptor alpha; Hypogonadism; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Motor Activity; Obesity; Physical Conditioning, Animal; Signal Transduction; Testosterone; Testosterone Congeners

2021
Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:11

    Topics: Aged; Aging; Body Mass Index; Cross-Sectional Studies; Dihydrotestosterone; Erectile Dysfunction; Geriatric Assessment; Humans; Hypogonadism; Male; Middle Aged; Surveys and Questionnaires; Symptom Assessment; Testosterone

2021
Urine and Serum Sex Steroid Profile in Testosterone-Treated Transgender and Hypogonadal and Healthy Control Men.
    The Journal of clinical endocrinology and metabolism, 2018, 06-01, Volume: 103, Issue:6

    Topics: Adolescent; Adult; Androgens; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogens; Estrone; Humans; Hypogonadism; Luteinizing Hormone; Male; Mass Spectrometry; Middle Aged; Testosterone; Transgender Persons; Transsexualism; Young Adult

2018
The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic genes in Leydig cells.
    Molecular and cellular endocrinology, 2013, May-06, Volume: 370, Issue:1-2

    Topics: Androgens; Androstenedione; Animals; Cells, Cultured; Cholesterol; Dihydrotestosterone; Gene Expression; Genotype; Hypogonadism; Leydig Cells; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mice; Mice, Knockout; Progesterone; Testosterone; Transcription Factors; Transcription, Genetic

2013
Serum level of testosterone, dihydrotestosterone and IGF-1 during an acute exacerbation of COPD and their relationships with inflammatory and prognostic indices: a pilot study.
    Minerva medica, 2014, Volume: 105, Issue:4

    Topics: Aged; APACHE; Biomarkers; Dihydrotestosterone; Disease Progression; Female; Humans; Hypogonadism; Inflammation; Insulin-Like Growth Factor I; Male; Pilot Projects; Prognosis; Pulmonary Disease, Chronic Obstructive; Reference Values; Serum Amyloid A Protein; Testosterone

2014
Sex steroids, precursors, and metabolite deficiencies in men with isolated hypogonadotropic hypogonadism and panhypopituitarism: a GCMS-based comparative study.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:2

    Topics: Adult; Androstenedione; Chromatography, Gas; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Humans; Hypogonadism; Hypopituitarism; Male; Mass Spectrometry; Progesterone; Testosterone; Young Adult

2015
Regulation of Sclerostin Production in Human Male Osteocytes by Androgens: Experimental and Clinical Evidence.
    Endocrinology, 2015, Volume: 156, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Adult; Androgens; Blotting, Western; Bone Morphogenetic Proteins; Case-Control Studies; Cells, Cultured; Dihydrotestosterone; Fluorescent Antibody Technique; Follicle Stimulating Hormone; Gene Expression Regulation; Gene Knockdown Techniques; Genetic Markers; Humans; Hypogonadism; In Vitro Techniques; Luteinizing Hormone; Male; Osteocytes; Osteoporosis; Parathyroid Hormone; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Young Adult

2015
Sex steroids during bone growth: a comparative study between mouse models for hypogonadal and senile osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:10

    Topics: Absorptiometry, Photon; Aging; Amino Acids; Animals; Bone Development; Dihydrotestosterone; Disease Models, Animal; Estradiol; Gonadal Steroid Hormones; Hormone Replacement Therapy; Hypogonadism; Male; Mice; Orchiectomy; Osteocalcin; Osteoporosis; Phenotype; Tomography, X-Ray Computed

2009
Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice.
    Reproductive biology and endocrinology : RB&E, 2009, Aug-27, Volume: 7

    Topics: Androgens; Animals; Cryptorchidism; Dihydrotestosterone; Disease Models, Animal; Female; Gonadotropins; Humans; Hypogonadism; Lithiasis; Male; Mice; Mice, Knockout; Receptors, Androgen; Sertoli Cells; Testicular Diseases; Testis; Testosterone

2009
Serum sex hormones and the 20-year risk of lower urinary tract symptoms in community-dwelling older men.
    BJU international, 2010, Volume: 105, Issue:11

    Topics: California; Dihydrotestosterone; Epidemiologic Methods; Humans; Hypogonadism; Independent Living; Male; Middle Aged; Prostatic Hyperplasia; Prostatism; Testosterone

2010
Testosterone may speed up the growth of prostate cancer due to aromatase activity.
    BJU international, 2010, Volume: 106, Issue:3

    Topics: Androgens; Dihydrotestosterone; Humans; Hypogonadism; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone

2010
Estradiol levels in men with congenital hypogonadotropic hypogonadism and the effects of different modalities of hormonal treatment.
    Fertility and sterility, 2011, Volume: 95, Issue:7

    Topics: Adolescent; Adult; Analysis of Variance; Androgens; Biomarkers; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Hormone Replacement Therapy; Humans; Hypogonadism; Klinefelter Syndrome; Luteinizing Hormone; Male; Middle Aged; Paris; Prospective Studies; Retrospective Studies; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome; Young Adult

2011
Association of hypogonadism with vitamin D status: the European Male Ageing Study.
    European journal of endocrinology, 2012, Volume: 166, Issue:1

    Topics: Adult; Aged; Cross-Sectional Studies; Dihydrotestosterone; Estradiol; Gas Chromatography-Mass Spectrometry; Humans; Hypogonadism; Immunoassay; Logistic Models; Luteinizing Hormone; Male; Middle Aged; Parathyroid Hormone; Sex Hormone-Binding Globulin; Testosterone; Vitamin D; Vitamin D Deficiency

2012
Androgen initiates Sertoli cell tight junction formation in the hypogonadal (hpg) mouse.
    Biology of reproduction, 2012, Volume: 87, Issue:2

    Topics: Androgens; Animals; Connexins; Dihydrotestosterone; Disease Models, Animal; Follicle Stimulating Hormone; Humans; Hypogonadism; Male; Mice; Mice, Transgenic; Organ Size; Rats; RNA, Messenger; Sertoli Cells; Tight Junctions

2012
Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues.
    Andrology, 2013, Volume: 1, Issue:1

    Topics: Aged; Androstenedione; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hypogonadism; Immunohistochemistry; Male; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone

2013
Androgen receptors in human synoviocytes and androgen regulation of interleukin 1beta (IL-1beta) induced IL-6 production: a link between hypoandrogenicity and rheumatoid arthritis?
    The Journal of rheumatology, 2002, Volume: 29, Issue:9

    Topics: Adolescent; Adult; Analysis of Variance; Arthritis, Rheumatoid; Cells, Cultured; Dihydrotestosterone; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypogonadism; Inflammation Mediators; Interleukin-1; Interleukin-6; Middle Aged; Probability; Receptors, Androgen; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Severity of Illness Index; Synovial Membrane

2002
Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:4

    Topics: Adipose Tissue; Androgen Antagonists; Androgens; Animals; Apolipoproteins B; Body Composition; Dihydrotestosterone; Drug Administration Schedule; Flutamide; Hypogonadism; Lipoproteins; Lipoproteins, LDL; Macaca fascicularis; Male; Mesentery; Orchiectomy; Testosterone

2004
Perinatal testosterone surge is required for normal adult bone size but not for normal bone remodeling.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:3

    Topics: Androgens; Animals; Bone and Bones; Bone Density; Bone Development; Bone Remodeling; Dihydrotestosterone; Femur; Hypogonadism; Male; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Orchiectomy; Osteocalcin; Testosterone; Tibia

2006
Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men.
    Archives of general psychiatry, 2006, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Affect; Androsterone; Cross-Over Studies; Dihydrotestosterone; Double-Blind Method; Estradiol; Humans; Hypogonadism; Injections, Intramuscular; Leuprolide; Male; Middle Aged; Radioimmunoassay; Sexual Behavior; Spinal Puncture; Testosterone

2006
Development of a highly sensitive and selective UPLC/MS/MS method for the simultaneous determination of testosterone and 5alpha-dihydrotestosterone in human serum to support testosterone replacement therapy for hypogonadism.
    Steroids, 2008, Volume: 73, Issue:6

    Topics: Chromatography, Liquid; Dihydrotestosterone; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Testosterone

2008
On the role of dihydrotestosterone in regulating luteinizing hormone secretion in man.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:5

    Topics: Adult; Castration; Cryptorchidism; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Luteinizing Hormone; Male; Testicular Diseases; Testosterone

1980
Responses to constant infusion of LH-RH in girls with primary hypogonadism.
    Obstetrics and gynecology, 1980, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Androstenedione; Child; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hydroxyprogesterones; Hypogonadism; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Progesterone; Testosterone; Turner Syndrome

1980
Which testosterone replacement therapy?
    Clinical endocrinology, 1984, Volume: 21, Issue:2

    Topics: Administration, Oral; Adult; Aged; Androstane-3,17-diol; Dihydrotestosterone; Drug Implants; Estradiol; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Testosterone

1984
Mild Hypogonadotropic hypogonadism in obese men.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Obesity; Pituitary Gland; Reference Values; Sperm Count; Sperm Motility; Testis; Testosterone

1982
Hormonal replacement and sexuality in men.
    Clinics in endocrinology and metabolism, 1982, Volume: 11, Issue:3

    Topics: Adult; Age Factors; Aged; Biotransformation; Castration; Dihydrotestosterone; Dose-Response Relationship, Drug; Erectile Dysfunction; Follicle Stimulating Hormone; Humans; Hypogonadism; Libido; Luteinizing Hormone; Male; Middle Aged; Sex Characteristics; Sexual Behavior; Testosterone

1982
Reassessment of the human chorionic gonadotropin stimulation test in hypogonadal males.
    Archives of andrology, 1982, Volume: 8, Issue:1

    Topics: Adult; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Gonadal Steroid Hormones; Humans; Hypogonadism; Male; Testosterone; Thyrotropin; Thyroxine; Triiodothyronine

1982
Percutaneous absorption of 5 alpha-dihydrotestosterone in man. II. Percutaneous administration of 5 alpha-dihydrotestosterone in hypogonadal men with idiopathic haemochromatosis; clinical, metabolic and hormonal effectiveness.
    International journal of andrology, 1982, Volume: 5, Issue:6

    Topics: Adult; Aged; Dihydrotestosterone; Double-Blind Method; Hemochromatosis; Humans; Hypogonadism; Kinetics; Male; Middle Aged; Skin Absorption

1982
Single vs. multiple dose hCG stimulated Leydig cell responses in eugonadal and hypogonadal subjects.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1994, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Child; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Kinetics; Leydig Cells; Male; Testosterone

1994
Microphallus: eventual phallic size is dependent on the timing of androgen administration.
    The Journal of urology, 1994, Volume: 152, Issue:2 Pt 2

    Topics: Animals; Dihydrotestosterone; Drug Administration Schedule; Gonadotropins, Pituitary; Hypogonadism; Immunohistochemistry; Male; Penis; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Time Factors

1994
Androgen regulation of circulating insulin-like growth factor-I during puberty in male hypogonadal mice.
    The Journal of endocrinology, 1993, Volume: 139, Issue:1

    Topics: Androgens; Animals; Body Weight; Cross-Sectional Studies; Dihydrotestosterone; Hypogonadism; Insulin-Like Growth Factor I; Kidney; Liver; Longitudinal Studies; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Organ Size; Seminal Vesicles; Sexual Maturation; Spleen; Testis; Testosterone

1993
Pharmacokinetics, bioefficacy, and safety of sublingual testosterone cyclodextrin in hypogonadal men: comparison to testosterone enanthate--a clinical research center study.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:12

    Topics: Administration, Sublingual; Adult; Blood; Blood Cell Count; Cyclodextrins; Dihydrotestosterone; Estradiol; Gonadotropins; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Sex Hormone-Binding Globulin; Sexual Behavior; Testosterone

1995
Pharmacokinetics and pharmacodynamics of subcutaneous testosterone implants in hypogonadal men.
    Clinical endocrinology, 1996, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Dihydrotestosterone; Drug Implants; Estradiol; Follicle Stimulating Hormone; Half-Life; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Patient Satisfaction; Sex Hormone-Binding Globulin; Testosterone; Time Factors

1996
Serum LH concentrations in hypogonadal men during transdermal testosterone replacement through scrotal skin: further evidence that ageing enhances testosterone negative feedback. The Testoderm Study Group.
    Clinical endocrinology, 1997, Volume: 47, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aging; Analysis of Variance; Dihydrotestosterone; Estradiol; Feedback; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Sex Hormone-Binding Globulin; Statistics, Nonparametric; Testosterone; Time Factors

1997
Long-term substitution therapy of hypogonadal men with transscrotal testosterone over 7-10 years.
    Clinical endocrinology, 1999, Volume: 50, Issue:5

    Topics: Administration, Cutaneous; Adult; Bone Density; Dihydrotestosterone; Estradiol; Follow-Up Studies; Humans; Hypogonadism; Male; Middle Aged; Prospective Studies; Prostate; Prostate-Specific Antigen; Scrotum; Testosterone

1999
Alterations in hepatic lipase and lipoprotein subfractions with transdermal testosterone replacement therapy.
    Clinical endocrinology, 1999, Volume: 51, Issue:6

    Topics: Administration, Cutaneous; Adult; Dihydrotestosterone; Hormone Replacement Therapy; Humans; Hypogonadism; Lipase; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Longitudinal Studies; Male; Testosterone

1999
Hypogonadism following prostate-bed radiation therapy for prostate carcinoma.
    Cancer, 2001, May-15, Volume: 91, Issue:10

    Topics: Aged; Aged, 80 and over; Dihydrotestosterone; Estradiol; Fertility Agents, Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Radiation Injuries; Testis; Testosterone

2001
Effects of oral testosterone undecanoate in hypogonadal male patients.
    Clinical endocrinology, 1978, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Androstenedione; Dihydrotestosterone; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Mental Processes; Middle Aged; Sexual Behavior; Testosterone; Thyrotropin-Releasing Hormone

1978
Testosterone-induced inhibition of the LH and FSH responses to gonadotropin-releasing hormone occurs slowly.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:6

    Topics: Adult; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Pituitary Hormone-Releasing Hormones; Testosterone

1977
Studies on the role of sex steroids in the feedback control of gonadotropin concentrations in men. III. Androgen resistance in primary gonadal failure.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:4

    Topics: Dihydrotestosterone; Estradiol; Feedback; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Testosterone

1979
[Effects of longterm HCG administration on testicular function in hemodialysis patients (author's transl)].
    Klinische Wochenschrift, 1976, Nov-01, Volume: 54, Issue:21

    Topics: Adult; Androstane-3,17-diol; Cell Count; Chorionic Gonadotropin; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; Hypogonadism; Kidney Failure, Chronic; Long-Term Care; Luteinizing Hormone; Male; Middle Aged; Renal Dialysis; Spermatozoa; Testosterone

1976
Gonadal function abnormalities in sickle cell anemia. Studies in adult male patients.
    Annals of internal medicine, 1976, Volume: 85, Issue:5

    Topics: Adolescent; Adult; Androstenedione; Anemia, Sickle Cell; Dihydrotestosterone; Erythrocytes; Female; Follicle Stimulating Hormone; Growth Disorders; Hair; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Sex Characteristics; Testosterone; Zinc

1976
Testosterone and 5alpha-androstan-17beta-ol-3-one (DHT) levels in man.
    Acta endocrinologica, 1976, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Aged; Androgen-Insensitivity Syndrome; Dihydrotestosterone; Female; Humans; Hypogonadism; Liver Cirrhosis; Male; Middle Aged; Portacaval Shunt, Surgical; Sex Factors; Testosterone

1976
[Studies on plasma 5 alpha-dihydrotestosterone (author's transl)].
    Nihon Funin Gakkai zasshi, 1976, Volume: 21, Issue:2

    Topics: Dihydrotestosterone; Female; Follicular Phase; Humans; Hypogonadism; Klinefelter Syndrome; Luteal Phase; Male; Pregnancy; Pregnancy Trimester, Third; Radioimmunoassay

1976
The hypothalamus and reproduction.
    American journal of obstetrics and gynecology, 1975, Aug-01, Volume: 122, Issue:7

    Topics: Acromegaly; Amenorrhea; Craniopharyngioma; Dihydrotestosterone; Estradiol; Female; Follicle Stimulating Hormone; Galactorrhea; Gonadotropin-Releasing Hormone; Gonadotropins; Half-Life; Humans; Hypogonadism; Hypopituitarism; Hypothalamus; Infertility; Luteinizing Hormone; Male; Oligospermia; Ovulation; Pituitary Neoplasms; Pregnancy; Radioimmunoassay; Reproduction; Steroids

1975
Dissociated responses of plasma testosterone and estradiol to human chorionic gonadotropin in adult men.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Gonadotropins; Humans; Hypogonadism; Male; Middle Aged; Radioimmunoassay; Testosterone

1975
Testosterone 5alpha-reduction in the skin of normal subjects and of patients with abnormal sex development.
    Acta endocrinologica, 1975, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Androgen-Insensitivity Syndrome; Androstanes; Child; Child, Preschool; Chorionic Gonadotropin; Depression, Chemical; Dihydrotestosterone; Estrogens; Female; Hirsutism; Humans; Hypogonadism; Male; Middle Aged; Oxidoreductases; Skin; Sterols; Stimulation, Chemical; Testosterone

1975
Radioimmunoassay of plasma dihydrotestosterone in normal and hypogonodal men.
    Clinical endocrinology, 1975, Volume: 4, Issue:5

    Topics: Adult; Age Factors; Aged; Dihydrotestosterone; Evaluation Studies as Topic; Humans; Hypogonadism; Klinefelter Syndrome; Male; Middle Aged; Oximes; Radioimmunoassay

1975
[Stimulation of testicular secretion by chorionic gonadotrophin. Results in normal men and in hypogonadic patients].
    La Nouvelle presse medicale, 1976, Mar-20, Volume: 5, Issue:12

    Topics: Adult; Aged; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Secretory Rate; Stimulation, Chemical; Testis; Testosterone

1976
Enhanced transdermal delivery of testosterone across nonscrotal skin produces physiological concentrations of testosterone and its metabolites in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Luteinizing Hormone; Middle Aged; Sex Hormone-Binding Globulin; Skin; Skin Absorption; Testosterone

1992
Sublingual administration of testosterone-hydroxypropyl-beta-cyclodextrin inclusion complex simulates episodic androgen release in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:5

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Sublingual; Adult; Androgens; Androstenedione; beta-Cyclodextrins; Cyclodextrins; Dihydrotestosterone; Drug Combinations; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Pilot Projects; Testosterone; Time Factors

1991
Testosterone replacement therapy and sleep-related erections in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:3

    Topics: Adult; Diagnosis, Differential; Dihydrotestosterone; Humans; Hypogonadism; Male; Middle Aged; Monitoring, Physiologic; Penile Erection; Sexual Dysfunctions, Psychological; Sleep Stages; Testosterone

1990
Treatment of primary hypogonadism in men by the transdermal administration of testosterone.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:2

    Topics: Administration, Cutaneous; Adult; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; Hypogonadism; Injections, Subcutaneous; Luteinizing Hormone; Male; Membranes, Artificial; Testosterone

1989
Testosterone replacement with transdermal therapeutic systems. Physiological serum testosterone and elevated dihydrotestosterone levels.
    JAMA, 1989, May-05, Volume: 261, Issue:17

    Topics: Administration, Cutaneous; Adult; Aged; Dihydrotestosterone; Humans; Hypogonadism; Male; Middle Aged; Scrotum; Testosterone; Time Factors

1989
Hypogonadism does not mediate urinary calcium loss in pituitary-grafted rats.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:8

    Topics: Calcium; Dihydrotestosterone; Estradiol; Female; Hyperprolactinemia; Hypogonadism; Male; Orchiectomy; Ovariectomy; Pituitary Gland, Anterior; Sodium; Testosterone

1989
Absorption of dihydrotestosterone (DHT) after its intramuscular administration.
    Fertility and sterility, 1989, Volume: 51, Issue:3

    Topics: Absorption; Adult; Delayed-Action Preparations; Dihydrotestosterone; Half-Life; Humans; Hypogonadism; Injections, Intramuscular; Male; Radioimmunoassay

1989
Transdermal testosterone therapy in the treatment of male hypogonadism.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:3

    Topics: Administration, Cutaneous; Androstane-3,17-diol; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Male; Testosterone

1988
Initial trial of slow-release testosterone microspheres in hypogonadal men.
    Fertility and sterility, 1988, Volume: 50, Issue:3

    Topics: Adult; Capsules; Delayed-Action Preparations; Dihydrotestosterone; Estradiol; Humans; Hypogonadism; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone

1988
Androgen levels and sex functions in testosterone-treated hypogonadal men.
    Archives of sexual behavior, 1987, Volume: 16, Issue:6

    Topics: Administration, Oral; Adult; Delayed-Action Preparations; Dihydrotestosterone; Drug Combinations; Humans; Hypogonadism; Injections; Male; Methyltestosterone; Middle Aged; Sexual Behavior; Tamoxifen; Testosterone; Time Factors

1987
[Depot mesterolone therapy in hypogonadism].
    Fortschritte der Andrologie, 1974, Volume: 3

    Topics: Adolescent; Adult; Delayed-Action Preparations; Dihydrotestosterone; Drug Evaluation; Humans; Hypogonadism; Injections, Intramuscular; Klinefelter Syndrome; Male; Mesterolone; Middle Aged; Sexual Maturation

1974
Gonadotrophin-releasing hormone therapy in hypogonadal males with hypothalamic or pituitary dysfunction.
    British medical journal, 1974, Dec-14, Volume: 4, Issue:5945

    Topics: Acromegaly; Adolescent; Adult; Brain Diseases; Brain Neoplasms; Craniopharyngioma; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Hypogonadism; Hypothalamus; Injections, Subcutaneous; Luteinizing Hormone; Male; Pituitary Diseases; Protein Binding; Puberty; Serum Globulins; Spermatogenesis; Testosterone

1974
Drugs in infertility.
    British medical journal, 1973, Jan-27, Volume: 1, Issue:5847

    Topics: Anabolic Agents; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Methane; Testosterone

1973
[Data on the hematic conversion of testosterone into dihydrotestosterone in subjects with hypogonadism].
    Folia endocrinologica, 1973, Volume: 26, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Dihydrotestosterone; Female; Follicle Stimulating Hormone; Humans; Hypogonadism; Luteinizing Hormone; Male; Testosterone

1973
Serum testosterone analysis by competitive protein binding: chromatography on silica-impregnated fiberglass and protein precipitation with ammonium sulfate.
    Biochemical medicine, 1972, Volume: 6, Issue:1

    Topics: Adult; Ammonium Sulfate; Androstanes; Blood; Chemical Precipitation; Chorionic Gonadotropin; Chromatography, Paper; Chromatography, Thin Layer; Dihydrotestosterone; Female; Humans; Hydroxysteroids; Hypogonadism; Male; Mathematics; Methods; Middle Aged; Pregnancy; Protein Binding; Testosterone; Tritium

1972
Further studies on the pathophysiology of testicular feminization syndrome.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adult; Androgen-Insensitivity Syndrome; Androstanes; Blood Proteins; Carbon Isotopes; Color Vision Defects; Dihydrotestosterone; Eunuchism; Humans; Hypogonadism; Intellectual Disability; Male; Olfaction Disorders; Protein Binding; Sex Chromosome Aberrations; Sterols; Testosterone; Tritium

1971
Anabolic effect of dihydrotestosterone in testicular feminization syndrome.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:9

    Topics: 17-Ketosteroids; Adult; Androgen-Insensitivity Syndrome; Body Weight; Castration; Cell Nucleus; Color Vision Defects; Creatinine; Dihydrotestosterone; Estrogens; Eunuchism; Humans; Hypogonadism; Intellectual Disability; Male; Nitrogen; Olfaction Disorders; Phosphates; Receptors, Drug; Sex Chromosome Aberrations; Stimulation, Chemical; Testosterone

1971
Studies on testosterone metabolism in human subjects with normal and pathological sexual differentiation.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:4

    Topics: 17-Ketosteroids; Adult; Androgen-Insensitivity Syndrome; Androstanes; Androsterone; Carbon Isotopes; Chorionic Gonadotropin; Dihydrotestosterone; Disorders of Sex Development; Glucuronates; Humans; Hypogonadism; Hypopituitarism; Male; Middle Aged; Sulfates; Testosterone; Tritium; Turner Syndrome

1968