dihydrotestosterone has been researched along with Hormone-Dependent Neoplasms in 123 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 31 (25.20) | 18.7374 |
1990's | 24 (19.51) | 18.2507 |
2000's | 46 (37.40) | 29.6817 |
2010's | 22 (17.89) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fedoruk, MN; Giménez-Bonafé, P; Guns, ES; Mayer, LD; Nelson, CC | 1 |
Bastow, KF; Lee, KH; Lin, L; Nyarko, AK; Shi, Q; Shih, CC; Su, CY; Wu, CC | 1 |
Armstrong, BK; Chrzanowska, A; Cumming, R; Egger, S; Handelsman, DJ; Le Couteur, D; Mason, R; Nair-Shalliker, V; Seibel, MJ; Smith, DP; Waite, L | 1 |
Han, H; Lin, SX; Poirier, D; Sang, X | 1 |
Argellati, F; Boccardo, F; Mangerini, R; Nuzzo, PV; Ricci, F; Rubagotti, A | 1 |
Barai, RS; Chaudhari, UK; Fernandes, G; Jacob, S; Kholkute, SD; Menon, S; Nayak, S; Sachdeva, G | 1 |
Amos-Landgraf, JM; Clipson, L; Dove, WF; Dunkin, E; Ederveen, AG; Groothuis, PG; Heijmans, J; Hommes, DW; Krentz, KJ; Mosselman, S; Muncan, V; Shedlovsky, A; van den Brink, GR; Wielenga, MC | 1 |
Patman, G | 1 |
Gooderham, NJ; Koufaris, C; Powell, C; Segal, CV | 1 |
Casimiro, MC; Chen, K; Crosariol, M; Di Sante, G; Gormley, M; Ju, X; Li, Z; Lisanti, MP; Meng, H; Pestell, RG; Yaman, I | 1 |
Brettes, JP; Mathelin, C | 1 |
Crews, CM; Cyrus, K; Deshaies, RJ; Kim, K; Rodriguez-Gonzalez, A; Sakamoto, KM; Salcius, M | 1 |
Bagalà, C; Barone, C; Bianchetti, S; Cassano, A; Fabiano, A; Landriscina, M; Piscazzi, A; Quirino, M; Schinzari, G; Sica, G | 1 |
Ji, J; Sun, Y; Tang, G; Wang, L; Xu, B; Xu, C; Zhang, Y | 1 |
Cerny, RL; Galbenus, R; Raza, A; Simpson, MA; Wei, Q | 1 |
Balk, S; Brown, M; Kantoff, P; Lee, GS; Sun, T; Wang, Q | 1 |
Kim, J; Li, J | 1 |
Al-Bataina, B; Chen, H; Dandekar, S; George, M; Ghosh, PM; Kung, HJ; Libertini, SJ; Mudryj, M; Tepper, CG | 1 |
Lyles, BE; Moss, PE; Stewart, LV | 1 |
Jalava, SE; Jenster, G; Kallioniemi, OP; Kohonen, PJ; Latonen, LM; Porkka, KP; Urbanucci, A; Visakorpi, T; Waltering, KK | 1 |
Aubé, M; Ayotte, P; Larochelle, C | 1 |
Jin, Y; Liu, ZW; Sun, HY; Tong, da Y; Wen, XQ; Wu, XY; Zhou, FJ | 1 |
Cross, P; Edmondson, RJ; Elattar, A; Freer, RM; Mukhopadhyay, A; Plummer, ER; Robson, CN; Shaheen, F; Warburton, KG | 1 |
Caradec, J; Chimingqi, M; de la Taille, A; Giton, F; Kouyoumdjian, JC; Loric, S; Moutereau, S; Sirab, N; Terry, S; Vacherot, F | 1 |
Haack, K; Kafri, T; Kantor, B; Li, X; Mohler, JL; Moore, DT; Titus, MA; Wilson, EM; Zeithaml, B | 1 |
Du, JB; Gai, JW; Guo, H; Jin, HF; Jin, J; Wang, Y | 1 |
Campbell, TJ; Figg, WD; Tindall, DJ | 1 |
Andriole, G; Castro-Santamaria, R; Freedland, SJ; Gerber, L; Moreira, DM; Muller, RL | 1 |
Morgentaler, A | 1 |
Jin, Y; Liu, Zw; Sun, Hy; Tong, da Y; Wu, Xy; Zhou, Fj | 1 |
Hartmann, MF; Kamrath, C; Wudy, S | 1 |
Fujinami, K; Ishiguro, H; Kubota, Y; Uemura, H | 1 |
Blackburn, GL; Franke, AA; Gaston, SM; Nassr, RL; Yu, L; Zhong, Y; Zhou, JR | 1 |
Banerjee, T; Nalbandian, GM; Pham, H; Ziboh, VA | 1 |
Herness, EA; Naz, RK | 1 |
Bruckheimer, EM; Logothetis, C; McDonnell, TJ; Spurgers, K; Weigel, NL | 1 |
Chen, F; Iwamoto, Y; Langenstroer, P; See, W; Zhang, G | 1 |
Altuwaijri, S; Chang, C; Chuang, KH; Hanchett, LA; Kang, HY; Lin, HK; Lin, WJ; Rahman, MM; Tsai, MY; Yang, L; Yeh, S; Zhang, Y | 1 |
Chen, SJ; Christman, JK; Igawa, T; Johansson, SL; Lee, MS; Lin, FF; Lin, JS; Lin, MF; Van Bemmel, D | 1 |
Fukabori, Y; Masuda, H; Nakano, K; Shimizu, N; Yamanaka, H | 1 |
Eto, H; Gleave, ME; Hara, I; Miyake, H | 1 |
Cheskis, B; Mancini, MA; Marcelli, M; McPhaul, MJ; Nan, B; Sun, S; Unni, E | 1 |
Coetzee, GA; Jia, L | 1 |
van der Poel, HG | 1 |
Garrett, MD; Mantoni, TS; Reid, G | 1 |
Gu, RG; Ma, QZ; Zhou, CW | 1 |
Adams, H; Berger, R; Garraway, LA; Hahn, WC; Lin, DI; Loda, M; Nieto, M; Sicinska, E; Signoretti, S | 1 |
Angelucci, C; Iacopino, F; Lama, G; Sica, G | 1 |
Brodie, A; Guo, Z; Macedo, LF; Qiu, Y; Sabnis, GJ; Tilghman, SL | 1 |
Barker, S; Puddefoot, JR; Vinson, GP | 1 |
Hara, N; Labrie, F; Nishiyama, T; Suzuki, K; Takahashi, K; Yamana, K | 1 |
Beliakoff, J; Brooks, JD; Li, TH; Peng, Y; Sun, Z; Zhao, H | 1 |
Arasheben, A; Barski, A; Buchanan, G; Coetzee, GA; Cogan, JP; Frenkel, B; Gerald, WL; Jariwala, U; Jia, L; Pregizer, S; Prescott, J; Scher, HI; Tilley, WD | 1 |
Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Ricevuto, E; Ventura, L; Vicentini, C | 1 |
Cunningham, GR; Ittmann, M; Li, H; Shao, TC | 1 |
Mahajna, J; Nevo, E; Wasser, SP; Zaidman, BZ | 1 |
Cai, LQ; Imperato-McGinley, JL; Qiao, Y; Tan, C; Zhang, ZK; Zhu, YS | 1 |
Gudkov, AV; Gurova, KV; Krivokrisenko, V; Narizhneva, N; Tararova, ND | 1 |
Byrns, MC; Penning, TM; Steckelbroeck, S | 1 |
Chung, S; Honma, S; Nakagawa, H; Nakamura, Y; Okuyama, A; Tamura, K; Uemura, M | 1 |
Farmer, PB; Gescher, AJ; Greaves, P; Mellon, JK; Pathak, S; Sharma, RA; Singh, R; Steward, WP; Verschoyle, RD | 1 |
Bruckheimer, EM; Kyprianou, N; Partin, JV; Strup, SE; Zhu, ML | 1 |
Balk, SP; Bao, BY; Brown, M; Chuang, BF; Kantoff, PW; Lee, GS; Sartor, O; Wang, Q | 1 |
Marts, SA; Mukherji, S; Padilla, GM; Petrow, V | 1 |
Kodama, T; Shimazaki, J | 1 |
Albert, JD; Geller, J | 1 |
Hoppen, HO; Izbicki, JR; Izbicki, W; Schmitz, R; Troidl, H | 1 |
Murayama, Y | 1 |
Albert, JD; de la Vega, DJ; Geller, J; Nachtsheim, DA | 1 |
Hamada, Y; Matsui, K; Nomura, Y; Saeki, K; Tashiro, H | 1 |
Fujii, H | 1 |
Fricks, CM; Mehta, RG; Moon, RC | 1 |
Korsten, CB; Persijn, JP; Rümke, P | 1 |
French, FS; Lea, OA | 1 |
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gatto, V; Leonardi, L | 1 |
Akimoto, S; Ichikawa, T; Shimazaki, J | 1 |
Barnard, J; Brass, AL; Patai, BL; Rukstalis, DB; Salvi, D | 1 |
Geller, J | 1 |
Brawley, OW; Ford, LG; Kramer, BS; Perlman, JA; Thompson, I | 1 |
Beck, S; Filmer, A; Hackenberg, R; Hushmand Nia, A; Koch, M; Kunzmann, R; Schulz, KD; Slater, EP | 1 |
Jones, RE; Loop, S; Meikle, AW; Ostenson, RC; Plymate, SR; Tuttle, RM | 1 |
Casamento, JB; Cockett, AT; Iwamura, M; Sluss, PM | 1 |
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L | 1 |
Feldman, D; Ly, LH; Peehl, DM; Zhao, XY | 1 |
Beaulieu, M; Bélanger, A; Guillemette, C; Hum, DW; Lévesque, E | 1 |
Labrie, C; Pouliot, F | 1 |
Cox, ME; Deeble, PD; Lakhani, S; Parsons, SJ | 1 |
Bell, DA; Lunn, RM; Mohler, JL; Taylor, JA | 1 |
Leung, LK; Wang, TT | 1 |
Becker, M; Cato, AC; Klocker, H; Mink, S; Peterziel, H; Schonert, A | 1 |
Hida, N; Labrie, F; Poulin, R; Veilleux, R | 1 |
Balczon, R; Chakrabarti, A; Hueser, CN; Ripple, M; Schatten, H; Taylor, M; Weindruch, R | 1 |
Heemers, H; Heyns, W; Swinnen, JV; Vanderhoydonc, F; Verhoeven, G | 1 |
Jeanteur, P | 1 |
Brown, GM; Pang, SF; Shiu, SY; Tam, PC; Xi, SC | 1 |
Ford, OH; French, FS; Gregory, CW; He, B; Johnson, RT; Mohler, JL; Wilson, EM | 1 |
Albert, J; de la Vega, D; Geller, J; Loza, D; Stoeltzing, W | 1 |
André, J; Garcia, M; Humeau, C; Rochefort, H; Vic, P | 1 |
Ascoli, M; Lacroix, A; McKenna, TJ; Puett, D | 1 |
Jellinghaus, W; Schroeder, FH | 1 |
Alford, TC; Do, HM; Geelhoed, GW; Lippman, ME; Tsangaris, NT | 1 |
King, RJ; Yates, J | 1 |
Baroni, M; Borsellino, G; Buonaguidi, A; Elli, G; Mondina, R; Poma, S; Rescalli, S; Sonato, A | 1 |
Fukabori, Y; McKeehan, WL; Nikolaropoulos, S; Wang, F; Yan, G | 1 |
Bellward, GD; Emerman, JT; Rowse, GJ; Weinberg, J | 1 |
Frei, E; Kantoff, PW; LeBlanc, GA; Ng, SF; Waxman, DJ | 1 |
Bohlken, S; Dijkstra, I; Geldof, AA; Meulenbroek, MF; Rao, BR | 1 |
Furuya, Y; Sato, N; Shimazaki, J; Watabe, Y | 1 |
de Jong, FH; Moerings, EP; Schröder, FH; van Kreuningen, A; van Steenbrugge, GJ; van Weerden, WM | 1 |
Robel, P | 1 |
Bruun, E; Frandsen, H; Frimodt-Møller, C; Nielsen, K; Rasmussen, LB; Vinnergaard, T | 1 |
Tohjoh, S | 1 |
Forbes, A; Iqbal, MJ; Johnson, PJ; Wilkinson, ML; Williams, R | 1 |
Bressel, M; Kastendieck, H; Klein, H; Voigt, KD | 1 |
Canellos, GP | 1 |
Crum, A; Handelsman, DJ; Peterson, M; Rajfer, J; Steiner, B; Swerdloff, RS | 1 |
Heston, WD; Kadmon, D | 1 |
Schröder, FH; van Steenbrugge, GJ | 1 |
Bell, C; Chang, SM; Chung, LW; Ro, JY; von Eschenbach, AC; Zhau, H | 1 |
Petrow, V | 1 |
Andriole, GL; Kish, ML; Linehan, WM; Loriaux, DL; Rittmaster, RS | 1 |
Mauvais-Jarvis, P; Mowszowicz, I; Portois, MC; Santen, RJ | 1 |
Kitamura, Y; Matsumoto, K; Nakamura, N; Nishizawa, Y; Noguchi, S; Sato, B; Uchida, N; Yamaguchi, K | 1 |
10 review(s) available for dihydrotestosterone and Hormone-Dependent Neoplasms
Article | Year |
---|---|
[Dual effects of androgens on mammary gland].
Topics: Age Factors; Androgen Antagonists; Androgens; Breast Neoplasms; Cell Proliferation; Dihydrotestosterone; Estradiol; Estrogens; Female; Humans; Mammary Glands, Human; Neoplasms, Hormone-Dependent; Polymorphism, Genetic; Receptors, Androgen; Receptors, Estrogen; Signal Transduction | 2008 |
Molecular profiles of finasteride effects on prostate carcinogenesis.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgens; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azasteroids; Dihydrotestosterone; Disease Progression; Dutasteride; Epithelial Cells; Finasteride; Humans; Isoenzymes; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Patient Selection; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Stromal Cells | 2009 |
[The alternative androgen synthesis pathway in humans].
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Androstenedione; Animals; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Infant; Infant, Newborn; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Pregnancy; Prostatic Neoplasms; Sex Differentiation; Steroid 21-Hydroxylase; Testis; Testosterone | 2013 |
Trilostane in advanced breast cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Hormone-Dependent; Postmenopause; Rats | 2006 |
[Recent findings on androgen receptors].
Topics: Animals; Cell Nucleus; Cytosol; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid; RNA | 1981 |
Endocrine therapy: predictors of response to prostatic cancer.
Topics: Androgen Antagonists; Cell Nucleus; Cytosol; Dihydrotestosterone; Humans; Male; Neoplasm Staging; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen | 1983 |
5-Alpha-reductase inhibition and prostate cancer prevention.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Cell Transformation, Neoplastic; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Risk Factors; Survival Rate | 1994 |
EB 33, an epithelial cell line from human prostate carcinoma: a review.
Topics: Acid Phosphatase; Animals; Cell Line; Chromosome Aberrations; Dihydrotestosterone; Epithelium; Glucosephosphate Dehydrogenase; Humans; Immunity; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Transplantation, Heterologous | 1978 |
Plasma steroid transport in subjects with tumors of hormonal target organs: a review.
Topics: Breast Neoplasms; Dihydrotestosterone; Endometrial Neoplasms; Estradiol; Female; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Sex Hormone-Binding Globulin | 1992 |
The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Animals; Dihydrotestosterone; Humans; Male; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Prostate; Prostatic Neoplasms; Rats; Testosterone | 1986 |
1 trial(s) available for dihydrotestosterone and Hormone-Dependent Neoplasms
Article | Year |
---|---|
Serum testosterone and dihydrotestosterone and prostate cancer risk in the placebo arm of the Reduction by Dutasteride of Prostate Cancer Events trial.
Topics: 5-alpha Reductase Inhibitors; Aged; Antineoplastic Agents, Hormonal; Azasteroids; Biopsy; Dihydrotestosterone; Double-Blind Method; Dutasteride; Humans; Kallikreins; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Grading; Neoplasms, Hormone-Dependent; Odds Ratio; Placebos; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design; Testosterone; Time Factors; Treatment Outcome; Up-Regulation | 2012 |
112 other study(ies) available for dihydrotestosterone and Hormone-Dependent Neoplasms
Article | Year |
---|---|
P-glycoprotein increases the efflux of the androgen dihydrotestosterone and reduces androgen responsive gene activity in prostate tumor cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Northern; Blotting, Western; Cyclosporins; Dihydrotestosterone; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Male; Neoplasms, Hormone-Dependent; Precipitin Tests; Prostatic Neoplasms; Receptors, Androgen; RNA, Neoplasm; Verapamil | 2004 |
Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents.
Topics: Androgen Antagonists; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Drug Design; Drug Screening Assays, Antitumor; Genes, Reporter; Humans; Luciferases; Male; Mutation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship; Transcriptional Activation; Transfection | 2006 |
Associations between sun sensitive pigmentary genes and serum prostate specific antigen levels.
Topics: Aged; Aged, 80 and over; Androgens; Australia; Dihydrotestosterone; Europe; Genes, Neoplasm; Genetic Predisposition to Disease; Humans; Male; Melanoma; Models, Genetic; Neoplasms, Hormone-Dependent; Neoplasms, Radiation-Induced; New Zealand; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Tolerance; Reference Values; Skin Neoplasms; Skin Pigmentation; Sunlight; Testosterone | 2018 |
Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism.
Topics: Aromatase Inhibitors; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Drug Therapy, Combination; Estradiol; Estradiol Dehydrogenases; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Hormone-Dependent; Steryl-Sulfatase; Sulfonic Acids; Tumor Cells, Cultured | 2018 |
Dihydrotestosterone and bicalutamide do not affect periostin expression in androgen-dependent LNCaP prostate cancer cell lines.
Topics: Androgens; Anilides; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; RNA, Messenger; Tosyl Compounds | 2013 |
Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer.
Topics: Androgens; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Dihydrotestosterone; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Immunoenzyme Techniques; Male; MicroRNAs; Neoplasms, Hormone-Dependent; Prostatic Hyperplasia; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Wound Healing; Zinc Finger E-box Binding Homeobox 2 | 2014 |
Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.
Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Animals, Congenic; Azoxymethane; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Genes, APC; Gonadal Steroid Hormones; Hormone Replacement Therapy; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mutation; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Specificity; Ovariectomy; Postmenopause; Random Allocation; Rats; Rats, Inbred F344; Rats, Mutant Strains; Receptors, Androgen; RNA, Messenger; Sex Distribution; Species Specificity | 2014 |
Colorectal cancer: male hormones increase the incidence of colonic adenomas.
Topics: Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Male; Neoplasms, Hormone-Dependent | 2015 |
Effects of treatment with androgen receptor ligands on microRNA expression of prostate cancer cells.
Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Ligands; Male; MicroRNAs; Nandrolone; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate-Specific Antigen; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Time Factors; Tosyl Compounds | 2015 |
Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells.
Topics: Animals; Cell Line, Tumor; Cyclin D1; Dihydrotestosterone; DNA Damage; DNA Repair; Histones; Humans; Male; Mice; Mice, Knockout; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Transfection | 2016 |
Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Drug Delivery Systems; Estradiol; Estrogen Receptor alpha; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Receptors, Androgen; Receptors, Steroid; Recombinant Fusion Proteins; Ubiquitination | 2008 |
Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Dihydrotestosterone; Docetaxel; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nevirapine; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Reverse Transcriptase Inhibitors; RNA, Neoplasm; Signal Transduction; Taxoids; Tosyl Compounds; Xenograft Model Antitumor Assays | 2009 |
Id-1 expression in androgen-dependent prostate cancer is negatively regulated by androgen through androgen receptor.
Topics: Androgens; Cell Line, Tumor; Dihydrotestosterone; Humans; Inhibitor of Differentiation Protein 1; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger | 2009 |
Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels.
Topics: Androgens; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Humans; Hyaluronic Acid; Male; Metribolone; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Uridine Diphosphate Glucose Dehydrogenase; Uridine Diphosphate Glucuronic Acid | 2009 |
The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines.
Topics: Androgens; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Gene Expression; Humans; Male; MicroRNAs; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Transfection | 2009 |
Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines.
Topics: Binding Sites; Cell Line, Tumor; Chromatin Immunoprecipitation; Dihydrotestosterone; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasms, Hormone-Dependent; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger | 2010 |
The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
Topics: Androgen-Binding Protein; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Gene Expression; Genes, Reporter; Humans; Hypoglycemic Agents; Male; Mutation; Neoplasms, Hormone-Dependent; PPAR gamma; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Transfection | 2010 |
Androgen regulation of micro-RNAs in prostate cancer.
Topics: Androgens; Animals; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; MicroRNAs; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transfection; Transplantation, Heterologous | 2011 |
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
Topics: Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Humans; Hydrocarbons, Chlorinated; Neoplasms, Hormone-Dependent; Receptors, Androgen; Regression Analysis | 2011 |
Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide.
Topics: Androgen Antagonists; Androgens; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2010 |
Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer.
Topics: Androgens; Ascitic Fluid; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cystadenocarcinoma, Serous; Dihydrotestosterone; Exons; Female; Humans; Immunohistochemistry; Neoplasm Grading; Neoplasms, Glandular and Epithelial; Neoplasms, Hormone-Dependent; Ovarian Neoplasms; Receptors, Androgen; RNA, Messenger; S Phase; Stimulation, Chemical; Trinucleotide Repeats; Tumor Cells, Cultured | 2012 |
Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells.
Topics: Adult; Anilides; Cell Line, Tumor; Cell Proliferation; Cinnamates; Dihydrotestosterone; Hedgehog Proteins; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Veratrum Alkaloids | 2012 |
Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer.
Topics: Androgens; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Genes, Dominant; Humans; Immunoblotting; Male; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Transcriptional Activation; Transplantation, Heterologous; Tumor Burden | 2012 |
Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells.
Topics: Adenocarcinoma; Androgens; Cell Line; Cell Line, Tumor; Culture Media; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dihydrotestosterone; Down-Regulation; Enzyme Induction; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Sulfide; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Receptors, Androgen; Stromal Cells | 2012 |
Dihydrotestosterone synthesis from adrenal precursors does not involve testosterone in castration-resistant prostate cancer.
Topics: Dihydrotestosterone; Disease Progression; Humans; Male; Molecular Targeted Therapy; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Testosterone | 2012 |
Goodbye androgen hypothesis, hello saturation model.
Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents, Hormonal; Azasteroids; Dihydrotestosterone; Dutasteride; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Testosterone | 2012 |
Expression changes and regulation of AR and IGF-1 in PC3 prostate cancer cells treated with sexual hormones and flutamide.
Topics: Androgen Antagonists; Androgens; Blotting, Western; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptors, Androgen; Signal Transduction; Tumor Cells, Cultured | 2012 |
Liprin-alpha2 gene, protein tyrosine phosphatase LAR interacting protein related gene, is downregulated by androgens in the human prostate cancer cell line LNCaP.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Androgens; Cycloheximide; Dihydrotestosterone; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Proteins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2002 |
Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components.
Topics: Animals; Apoptosis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dihydrotestosterone; Glycine max; Humans; Isoflavones; Lung Neoplasms; Lymph Nodes; Male; Mice; Mice, SCID; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Plant Extracts; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Soybean Proteins; Specific Pathogen-Free Organisms; Testosterone; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2002 |
Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Division; Dihydrotestosterone; Eicosanoic Acids; Flow Cytometry; gamma-Linolenic Acid; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2003 |
A novel human prostate-specific gene-1 (HPG-1): molecular cloning, sequencing, and its potential involvement in prostate carcinogenesis.
Topics: Amino Acid Sequence; Base Sequence; Cell Adhesion Molecules; Cell Division; Cloning, Molecular; Dihydrotestosterone; DNA, Complementary; Humans; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Polymerase Chain Reaction; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 2003 |
Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells.
Topics: Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Up-Regulation | 2003 |
Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.
Topics: Androgen Antagonists; Anilides; Autocrine Communication; BCG Vaccine; Carcinoma, Transitional Cell; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Genes, Reporter; Humans; Neoplasms, Hormone-Dependent; NF-kappa B; Nitriles; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vaccines, Attenuated | 2003 |
Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells.
Topics: Androgens; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Dihydrotestosterone; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; NF-kappa B; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transfection | 2003 |
p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Breast Neoplasms; Cell Division; Dihydrotestosterone; Estrogens; Humans; Male; Neoplasms, Hormone-Dependent; Phosphorylation; Prostate; Prostatic Neoplasms; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Testicular Neoplasms; Tumor Cells, Cultured; Up-Regulation | 2004 |
Expression of bone morphogenetic protein-7 (BMP-7) in human prostate.
Topics: Aged; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2004 |
Protection of androgen-dependent human prostate cancer cells from oxidative stress-induced DNA damage by overexpression of clusterin and its modulation by androgen.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Androgens; Apoptosis; Clusterin; Deoxyguanosine; Dihydrotestosterone; DNA Damage; DNA, Complementary; Gene Expression; Glycoproteins; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Molecular Chaperones; Neoplasms, Hormone-Dependent; Oxidative Stress; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured | 2004 |
Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.
Topics: Activating Transcription Factor 1; Anilides; Animals; Cell Line, Tumor; Co-Repressor Proteins; Dihydrotestosterone; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; src-Family Kinases; Tosyl Compounds; Trans-Activators; Transcription Factors | 2004 |
Androgen receptor-dependent PSA expression in androgen-independent prostate cancer cells does not involve androgen receptor occupancy of the PSA locus.
Topics: Cell Line, Tumor; Chromatin Immunoprecipitation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Androgen; RNA, Messenger; Transfection | 2005 |
Androgen receptor and TGFbeta1/Smad signaling are mutually inhibitory in prostate cancer.
Topics: Apoptosis; Dihydrotestosterone; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Up-Regulation | 2005 |
Androgen receptor activity is inhibited in response to genotoxic agents in a p53-independent manner.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Chromatin Immunoprecipitation; Cisplatin; Dihydrotestosterone; Etoposide; Humans; Ligands; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Subcellular Fractions; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2006 |
[Effect of dihydrotestosterone on the transcriptions and expressions of Smad3 and Smad4 in LNCaP cell line].
Topics: Androgens; Cell Line, Tumor; Dihydrotestosterone; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad4 Protein; Transcription, Genetic | 2006 |
Androgen-dependent regulation of Her-2/neu in prostate cancer cells.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Mice; Neoplasms, Hormone-Dependent; Phosphorylation; Prostatic Neoplasms; Receptor, ErbB-2; Receptors, Androgen; RNA, Messenger; RNA, Small Interfering; Transfection | 2006 |
Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells.
Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Leuprolide; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms, Hormone-Dependent; Phosphorylation; Prostatic Neoplasms; Protein Kinase Inhibitors; Quinazolines; Time Factors; Tyrphostins | 2006 |
Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole.
Topics: Androgen Receptor Antagonists; Androgens; Androstenedione; Aromatase; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; RNA, Small Interfering; Transfection; Triazoles | 2006 |
Importance of the intracrine metabolism of adrenal androgens in androgen-dependent prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Glands; Androgens; Cell Line, Tumor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells.
Topics: Adenoviridae; Androgen Receptor Antagonists; Androgens; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Down-Regulation; Gene Expression Regulation; Male; Mice; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Transcriptional Activation; Xenograft Model Antitumor Assays | 2007 |
Identification of novel androgen receptor target genes in prostate cancer.
Topics: Adenocarcinoma; Androgens; Binding Sites; Cell Adhesion Molecules; Cell Line, Tumor; Chromosomes, Human; delta-1-Pyrroline-5-Carboxylate Reductase; Dihydrotestosterone; Extracellular Matrix Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Intracellular Signaling Peptides and Proteins; Male; Mucin-6; Mucins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Ornithine-Oxo-Acid Transaminase; Prostatic Neoplasms; Protein Kinase C-delta; Pyrroline Carboxylate Reductases; Receptors, Androgen; Transcription, Genetic; TRPV Cation Channels | 2007 |
In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma.
Topics: Adult; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents; Blotting, Western; Carbazoles; Carcinoma; Cell Line, Tumor; Cohort Studies; Dihydrotestosterone; Furans; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Tosyl Compounds | 2007 |
Effects of dutasteride on prostate growth in the large probasin-large T antigen mouse model of prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Animals; Antigens, Viral, Tumor; Apoptosis; Azasteroids; Cell Division; Cell Transformation, Neoplastic; Dihydrotestosterone; Disease Models, Animal; Dutasteride; Enzyme Inhibitors; Female; Male; Membrane Proteins; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Seminal Vesicles; Transgenes | 2007 |
Androgen receptor-dependent and -independent mechanisms mediate Ganoderma lucidum activities in LNCaP prostate cancer cells.
Topics: Annexin A5; Apoptosis; Caspase 3; Caspase 8; Cell Proliferation; Cyclin D; Cyclins; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasms, Hormone-Dependent; Plant Extracts; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Receptors, Androgen; Reishi; Tumor Cells, Cultured | 2007 |
17alpha-estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals.
Topics: Animals; Blotting, Western; Cell Growth Processes; Cell Line, Tumor; Cyclin A; Cyclin D1; Dihydrotestosterone; Estradiol; Gene Expression; Humans; Male; Mice; Mice, SCID; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stereoisomerism; Xenograft Model Antitumor Assays | 2007 |
Prostate cancer cells tolerate a narrow range of androgen receptor expression and activity.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription, Genetic; Transfection | 2007 |
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone indepe
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Catalysis; Dihydrotestosterone; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Indoles; Indomethacin; Melatonin; Neoplasms, Hormone-Dependent; Oxidation-Reduction; Phenanthrenes | 2008 |
Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Cell Growth Processes; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; RNA, Small Interfering; Testosterone; Transfection | 2008 |
Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo.
Topics: Androgens; Animals; Cell Line, Tumor; Dihydrotestosterone; DNA Adducts; DNA Damage; Flutamide; Humans; Male; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reactive Oxygen Species | 2008 |
TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells.
Topics: Androgen-Binding Protein; Apoptosis; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Drug Synergism; Humans; Luciferases; Male; Microscopy, Fluorescence; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Androgen; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad4 Protein; Transcriptional Activation; Transfection; Transforming Growth Factor beta | 2008 |
Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.
Topics: Androgen Receptor Antagonists; Cell Line, Tumor; Dihydrotestosterone; Down-Regulation; Gene Expression; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Humans; Male; Minor Histocompatibility Antigens; Neoplasms, Hormone-Dependent; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; RNA Interference | 2008 |
Endocrine dependence of prostatic cancer upon dihydrotestosterone and not upon testosterone.
Topics: Adenocarcinoma; Animals; Cells, Cultured; Dihydrotestosterone; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Progesterone; Prostatic Neoplasms; Rats; Testosterone | 1984 |
Effects of steroid hormone therapy on primarily xenotransplanted human colorectal adenocarcinomas.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dihydrotestosterone; Estradiol; Female; Hormones; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Progesterone; Receptors, Estrogen; Receptors, Progesterone; Rectal Neoplasms; Transplantation, Heterologous | 1984 |
Plasma sex hormone-binding globulin (SHBG) and obesity in breast cancer patients.
Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Mastectomy; Neoplasms, Hormone-Dependent; Obesity; Risk; Sex Hormone-Binding Globulin | 1983 |
Tissue dihydrotestosterone levels and clinical response to hormonal therapy in patients with advanced prostate cancer.
Topics: Androgen Antagonists; Cell Nucleus; Cytosol; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen | 1984 |
[Evaluation of steroid hormone sensitivity of human breast cancer cells in culture (MCF-7) by a colony formation method].
Topics: Breast Neoplasms; Cells, Cultured; Colony-Forming Units Assay; Dihydrotestosterone; Estradiol; Female; Humans; Neoplasms, Hormone-Dependent; Progesterone | 1983 |
[Histological and endocrinological studies on prostatic carcinoma (author's transl)].
Topics: Aged; Biotransformation; Dihydrotestosterone; Histocytochemistry; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Testosterone | 1981 |
Androgen receptors in chemically-induced colon carcinogenesis.
Topics: Animals; Castration; Colonic Neoplasms; Dihydrotestosterone; Dimethylhydrazines; Female; Male; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Ovary; Rats; Receptors, Androgen; Receptors, Steroid; Testis | 1980 |
Oestrogen and androgen receptors in melanoma.
Topics: Adult; Aged; Dihydrotestosterone; Estradiol; Female; Humans; Male; Melanoma; Middle Aged; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid | 1980 |
Androgen receptor protein in the androgen-dependent Dunning R-3327 prostate carcinoma.
Topics: Animals; Castration; Cytosol; Dihydrotestosterone; Kinetics; Male; Molecular Weight; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid; Testosterone | 1981 |
Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Flutamide; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tumor Cells, Cultured | 1995 |
An inhibitory effect of TZP-4238 on the growth of androgen-sensitive rat prostatic tumor (Dunning R3327).
Topics: Administration, Oral; Androgen Antagonists; Androgens; Animals; Chlormadinone Acetate; Dihydrotestosterone; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Size; Prostate; Prostatic Neoplasms; Rats; Testis; Testosterone | 1993 |
Androgen up-regulates epidermal growth factor receptor expression and binding affinity in PC3 cell lines expressing the human androgen receptor.
Topics: Adenocarcinoma; Androgens; Animals; Bone Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Mice; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Stimulation, Chemical; Transforming Growth Factor alpha; Tumor Cells, Cultured; Up-Regulation | 1995 |
Basis for hormonal management of advanced prostate cancer.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Biosynthesis; Rats; Testosterone | 1993 |
Androgen responsiveness of the new human endometrial cancer cell line MFE-296.
Topics: Androgens; Animals; Base Sequence; Cell Division; Dihydrotestosterone; DNA, Neoplasm; Endometrial Neoplasms; Female; Humans; Karyotyping; Mice; Mice, Nude; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Phenotype; Progestins; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Transfection; Tumor Cells, Cultured | 1994 |
Effect of 5-alpha-reductase inhibition and dexamethasone administration on the growth characteristics and intratumor androgen levels of the human prostate cancer cell line PC-3.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Animals; Azasteroids; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Random Allocation; Testosterone; Tumor Cells, Cultured | 1994 |
Insulin-like growth factor I: action and receptor characterization in human prostate cancer cell lines.
Topics: Binding, Competitive; Cell Division; Culture Media, Serum-Free; Dihydrotestosterone; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptor, IGF Type 1; Tumor Cells, Cultured | 1993 |
Indirect growth inhibition of the MDA-MB-231 hormone-independent breast cancer cell line by dihydrotestosterone.
Topics: Breast Neoplasms; Cell Division; Dihydrotestosterone; Female; Humans; Neoplasms, Hormone-Dependent; Receptors, Androgen; Tumor Cells, Cultured | 1996 |
1alpha,25-dihydroxyvitamin D3 actions in LNCaP human prostate cancer cells are androgen-dependent.
Topics: Analysis of Variance; Androgen Antagonists; Androgens; Anilides; Blotting, Northern; Blotting, Western; Calcitriol; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tritium; Tumor Cells, Cultured; Up-Regulation | 1997 |
Effect of fibroblastic growth factors (FGF) on steroid UDP-glucuronosyltransferase expression and activity in the LNCaP cell line.
Topics: Androgens; Cell Division; Dihydrotestosterone; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Gene Expression; Glucuronates; Glucuronosyltransferase; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Steroids; Tumor Cells, Cultured | 1998 |
Expression profile of agonistic Smads in human breast cancer cells: absence of regulation by estrogens.
Topics: Breast Neoplasms; Dihydrotestosterone; DNA-Binding Proteins; Estrogens; Humans; Neoplasms, Hormone-Dependent; RNA, Messenger; Smad2 Protein; Smad3 Protein; Smad4 Protein; Trans-Activators; Transforming Growth Factor beta; Tumor Cells, Cultured | 1999 |
Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Androgens; Biomarkers; Bombesin; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Lineage; Chromogranin A; Chromogranins; Colforsin; Cyclic AMP; Cytoplasmic Granules; Dihydrotestosterone; Disease Progression; Epinephrine; Humans; Isoproterenol; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neoplastic Stem Cells; Neuroendocrine Tumors; Neurotensin; Parathyroid Hormone-Related Protein; Phenotype; Phosphopyruvate Hydratase; Prostatic Neoplasms; Protein-Tyrosine Kinases; Proteins; Second Messenger Systems; Serotonin; Tumor Cells, Cultured | 1999 |
Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2).
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenocarcinoma; Asian People; Black People; Case-Control Studies; Dihydrotestosterone; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Isoenzymes; Male; Neoplasms, Hormone-Dependent; North Carolina; Odds Ratio; Polymorphism, Genetic; Prostatic Neoplasms; Risk; Steroid 17-alpha-Hydroxylase; Taiwan; Testosterone; White People | 1999 |
Paradoxical regulation of Bcl-2 family proteins by 17beta-oestradiol in human breast cancer cells MCF-7.
Topics: Adenocarcinoma; Apoptosis; bcl-X Protein; Breast Neoplasms; Cell Count; Dihydrotestosterone; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Tamoxifen | 1999 |
Rapid signalling by androgen receptor in prostate cancer cells.
Topics: Adenocarcinoma; Androgen Antagonists; Cell Nucleus; Cytoplasm; Dihydrotestosterone; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Ligands; Male; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptors, Androgen; Recombinant Fusion Proteins; Testosterone; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1999 |
Differential androgen sensitivity is associated with clonal heterogeneity in steroid metabolism, ornithine decarboxylase regulation and IL-1alpha action in mouse mammary tumor cells.
Topics: Androgens; Androstenediol; Androstenedione; Animals; Binding Sites; Cell Division; Clone Cells; Dehydroepiandrosterone; Dihydrotestosterone; Interleukin-1; Male; Mammary Neoplasms, Experimental; Mice; Mitogens; Neoplasms, Hormone-Dependent; Ornithine Decarboxylase; Steroids; Testosterone; Tumor Cells, Cultured | 1999 |
Androgen and taxol cause cell type-specific alterations of centrosome and DNA organization in androgen-responsive LNCaP and androgen-independent DU145 prostate cancer cells.
Topics: Androgens; Antineoplastic Agents, Phytogenic; Cell Division; Centrosome; Dihydrotestosterone; DNA, Neoplasm; Humans; Male; Metribolone; Microscopy, Electron; Microscopy, Fluorescence; Neoplasms, Hormone-Dependent; Paclitaxel; Prostatic Neoplasms; Testosterone Congeners | 2000 |
Progestins and androgens increase expression of Spot 14 in T47-D breast tumor cells.
Topics: Breast Neoplasms; Chromosomes, Human, Pair 11; Dihydrotestosterone; Female; Gene Expression; Humans; Lipids; Metribolone; Neoplasms, Hormone-Dependent; Nuclear Proteins; Pregnenediones; Progesterone; Progesterone Congeners; Proteins; Testosterone Congeners; Transcription Factors; Tumor Cells, Cultured | 2000 |
[Perhaps an explanation for the therapeutic escape of prostate cancer treated with antiandrogens].
Topics: Androgen Antagonists; Dihydrotestosterone; Drug Resistance, Neoplasm; Humans; Hydrocortisone; Male; Neoplasms, Hormone-Dependent; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Tumor Cells, Cultured; X Chromosome | 2000 |
Potential involvement of mt1 receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells.
Topics: Adenocarcinoma; Blotting, Western; Calcium; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Humans; Immunoenzyme Techniques; Male; Melatonin; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2000 |
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy.
Topics: Aged; Androgen Antagonists; Animals; Dihydrotestosterone; Histone Acetyltransferases; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivator 2; Orchiectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Transcription Factors; Transcriptional Activation; Transplantation, Heterologous | 2001 |
Dihydrotestosterone concentration in prostate cancer tissue as a predictor of tumor differentiation and hormonal dependency.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Cell Differentiation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid | 1978 |
[Early effect of estradiol on ultrastructure of chromatin in the endometrium and hormone-dependent mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Chromatin; Dihydrotestosterone; Endometrium; Estradiol; Female; Heterochromatin; In Vitro Techniques; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Rats; Receptors, Estrogen; Sheep; Tamoxifen; Time Factors | 1978 |
Steroidogenesis in HCG-responsive Leydig cell tumor variants.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Chorionic Gonadotropin; Dihydrotestosterone; Hydroxyprogesterones; Leydig Cell Tumor; Male; Mice; Neoplasms, Hormone-Dependent; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone | 1979 |
Steroid hormone receptors in human colon cancers.
Topics: Breast Neoplasms; Colonic Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Steroid | 1979 |
Multiple sensitivities of mammary tumor cells in culture.
Topics: Animals; Cell Count; Cell Division; Cell Line; Culture Media; Dexamethasone; Dihydrotestosterone; Drug Resistance; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Testosterone | 1978 |
Heparin-binding keratinocyte growth factor is a candidate stromal-to-epithelial-cell andromedin.
Topics: Animals; Base Sequence; Cell Division; Cells, Cultured; Connective Tissue; Connective Tissue Cells; Dihydrotestosterone; Epithelial Cells; Epithelium; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Growth Substances; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Protein-Tyrosine Kinases; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Testosterone; Tumor Cells, Cultured | 1992 |
Endocrine mediation of psychosocial stressor effects on mouse mammary tumor growth.
Topics: Analysis of Variance; Animals; Cell Division; Corticosterone; Dihydrotestosterone; Hydrocortisone; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Glucocorticoid; Stress, Psychological; Testosterone; Tumor Cells, Cultured | 1992 |
Hormonal perturbations in patients with testicular cancer treated with cisplatin.
Topics: Adult; Androstenedione; Chorionic Gonadotropin; Cisplatin; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Neoplasms, Hormone-Dependent; Testicular Neoplasms; Testosterone | 1992 |
Consideration of the use of 17 beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5- alpha-androstan-3-one (4MA), a 5 alpha-reductase inhibitor, in prostate cancer therapy.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Animals; Azasteroids; Cell Division; Cell Survival; Dihydrotestosterone; Female; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Organ Size; Prostate; Prostatic Neoplasms; Rats; Steroids | 1992 |
Effects of estrogen on growth of androgen-responsive rat prostatic tumor (R 3327).
Topics: Animals; Castration; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Humans; Injections, Subcutaneous; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Organ Size; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Seminal Vesicles; Sex Factors; Testosterone | 1991 |
Assessment of the critical level of androgen for growth response of transplantable human prostatic carcinoma (PC-82) in nude mice.
Topics: Animals; Dihydrotestosterone; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Testosterone | 1991 |
[Hormone-dependency of the human prostate].
Topics: Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid | 1986 |
Dihydrotestosterone measured in core biopsies from prostatic tissues.
Topics: Aged; Aged, 80 and over; Biopsy; Cell Nucleus; Dihydrotestosterone; DNA; DNA, Neoplasm; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms | 1988 |
[A study on usefulness of the crude nuclear DHT measurement in prostatic cancer patients].
Topics: Androgens; Cell Nucleus; Dihydrotestosterone; Humans; Male; Methods; Neoplasms, Hormone-Dependent; Predictive Value of Tests; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen | 1989 |
Response to cyproterone acetate treatment in primary hepatocellular carcinoma is related to fall in free 5 alpha-dihydrotestosterone.
Topics: Adult; Aged; Androgen Antagonists; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasms, Hormone-Dependent | 1987 |
Androgens, adrenal androgen precursors, and their metabolism in untreated primary tumors and lymph node metastases of human prostatic cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Androgens; Androstenediols; Androstenedione; Arylsulfatases; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Humans; Lymphatic Metastasis; Male; Neoplasms, Hormone-Dependent; Oxidoreductases; Prostate; Prostatic Neoplasms; Steryl-Sulfatase; Testosterone | 1988 |
Hormonal agents and treatment of cancer.
Topics: Androgens; Breast Neoplasms; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Female; Flutamide; Hormones; Humans; Male; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen | 1986 |
Comparison of the efficacy of subcutaneous and nasal spray buserelin treatment in suppression of testicular steroidogenesis in men with prostate cancer.
Topics: Administration, Intranasal; Aged; Buserelin; Dihydrotestosterone; Drug Evaluation; Estradiol; Gonadal Steroid Hormones; Humans; Injections, Subcutaneous; Luteinizing Hormone; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prospective Studies; Prostatic Neoplasms; Random Allocation; Testis; Testosterone | 1986 |
alpha-Difluoromethylornithine enhancement of 14C-putrescine uptake by an androgen-dependent prostatic tumor.
Topics: Adenocarcinoma; Androgens; Animals; Carbon Radioisotopes; Dexamethasone; Dihydrotestosterone; Eflornithine; Male; Neoplasms, Hormone-Dependent; Premedication; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats | 1986 |
Androgen-dependent human prostate cancer in nude mice. The PC-82 tumor model.
Topics: Adenocarcinoma; Animals; Dihydrotestosterone; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Testosterone | 1988 |
Prostatic carcinogenesis evoked by cellular interaction.
Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Epithelium; Fibroblasts; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Tumor Cells, Cultured | 1988 |
The effect of 4MA, a potent inhibitor of 5 alpha-reductase, on the growth of androgen-responsive human genitourinary tumors grown in athymic nude mice.
Topics: 5-alpha Reductase Inhibitors; Androgens; Animals; Azasteroids; Dihydrotestosterone; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Steroids, Heterocyclic; Transplantation, Heterologous | 1987 |
Androgen dependence of the Dunning R3327G cell line in monolayer culture.
Topics: Androgen Antagonists; Androgens; Animals; Cell Division; Cell Line; Dihydrotestosterone; Flutamide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Rats; Tumor Cells, Cultured | 1987 |
Growth-stimulating effect of pharmacological doses of estrogen on androgen-dependent Shionogi carcinoma 115 in vivo but not in cell culture.
Topics: Androgens; Animals; Blood Physiological Phenomena; Carcinoma; Cell Division; Cells, Cultured; Culture Media; Dihydrotestosterone; Estradiol; Estrogens; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Testosterone | 1987 |