Page last updated: 2024-08-21

dihydrotestosterone and Hormone-Dependent Neoplasms

dihydrotestosterone has been researched along with Hormone-Dependent Neoplasms in 123 studies

Research

Studies (123)

TimeframeStudies, this research(%)All Research%
pre-199031 (25.20)18.7374
1990's24 (19.51)18.2507
2000's46 (37.40)29.6817
2010's22 (17.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fedoruk, MN; Giménez-Bonafé, P; Guns, ES; Mayer, LD; Nelson, CC1
Bastow, KF; Lee, KH; Lin, L; Nyarko, AK; Shi, Q; Shih, CC; Su, CY; Wu, CC1
Armstrong, BK; Chrzanowska, A; Cumming, R; Egger, S; Handelsman, DJ; Le Couteur, D; Mason, R; Nair-Shalliker, V; Seibel, MJ; Smith, DP; Waite, L1
Han, H; Lin, SX; Poirier, D; Sang, X1
Argellati, F; Boccardo, F; Mangerini, R; Nuzzo, PV; Ricci, F; Rubagotti, A1
Barai, RS; Chaudhari, UK; Fernandes, G; Jacob, S; Kholkute, SD; Menon, S; Nayak, S; Sachdeva, G1
Amos-Landgraf, JM; Clipson, L; Dove, WF; Dunkin, E; Ederveen, AG; Groothuis, PG; Heijmans, J; Hommes, DW; Krentz, KJ; Mosselman, S; Muncan, V; Shedlovsky, A; van den Brink, GR; Wielenga, MC1
Patman, G1
Gooderham, NJ; Koufaris, C; Powell, C; Segal, CV1
Casimiro, MC; Chen, K; Crosariol, M; Di Sante, G; Gormley, M; Ju, X; Li, Z; Lisanti, MP; Meng, H; Pestell, RG; Yaman, I1
Brettes, JP; Mathelin, C1
Crews, CM; Cyrus, K; Deshaies, RJ; Kim, K; Rodriguez-Gonzalez, A; Sakamoto, KM; Salcius, M1
Bagalà, C; Barone, C; Bianchetti, S; Cassano, A; Fabiano, A; Landriscina, M; Piscazzi, A; Quirino, M; Schinzari, G; Sica, G1
Ji, J; Sun, Y; Tang, G; Wang, L; Xu, B; Xu, C; Zhang, Y1
Cerny, RL; Galbenus, R; Raza, A; Simpson, MA; Wei, Q1
Balk, S; Brown, M; Kantoff, P; Lee, GS; Sun, T; Wang, Q1
Kim, J; Li, J1
Al-Bataina, B; Chen, H; Dandekar, S; George, M; Ghosh, PM; Kung, HJ; Libertini, SJ; Mudryj, M; Tepper, CG1
Lyles, BE; Moss, PE; Stewart, LV1
Jalava, SE; Jenster, G; Kallioniemi, OP; Kohonen, PJ; Latonen, LM; Porkka, KP; Urbanucci, A; Visakorpi, T; Waltering, KK1
Aubé, M; Ayotte, P; Larochelle, C1
Jin, Y; Liu, ZW; Sun, HY; Tong, da Y; Wen, XQ; Wu, XY; Zhou, FJ1
Cross, P; Edmondson, RJ; Elattar, A; Freer, RM; Mukhopadhyay, A; Plummer, ER; Robson, CN; Shaheen, F; Warburton, KG1
Caradec, J; Chimingqi, M; de la Taille, A; Giton, F; Kouyoumdjian, JC; Loric, S; Moutereau, S; Sirab, N; Terry, S; Vacherot, F1
Haack, K; Kafri, T; Kantor, B; Li, X; Mohler, JL; Moore, DT; Titus, MA; Wilson, EM; Zeithaml, B1
Du, JB; Gai, JW; Guo, H; Jin, HF; Jin, J; Wang, Y1
Campbell, TJ; Figg, WD; Tindall, DJ1
Andriole, G; Castro-Santamaria, R; Freedland, SJ; Gerber, L; Moreira, DM; Muller, RL1
Morgentaler, A1
Jin, Y; Liu, Zw; Sun, Hy; Tong, da Y; Wu, Xy; Zhou, Fj1
Hartmann, MF; Kamrath, C; Wudy, S1
Fujinami, K; Ishiguro, H; Kubota, Y; Uemura, H1
Blackburn, GL; Franke, AA; Gaston, SM; Nassr, RL; Yu, L; Zhong, Y; Zhou, JR1
Banerjee, T; Nalbandian, GM; Pham, H; Ziboh, VA1
Herness, EA; Naz, RK1
Bruckheimer, EM; Logothetis, C; McDonnell, TJ; Spurgers, K; Weigel, NL1
Chen, F; Iwamoto, Y; Langenstroer, P; See, W; Zhang, G1
Altuwaijri, S; Chang, C; Chuang, KH; Hanchett, LA; Kang, HY; Lin, HK; Lin, WJ; Rahman, MM; Tsai, MY; Yang, L; Yeh, S; Zhang, Y1
Chen, SJ; Christman, JK; Igawa, T; Johansson, SL; Lee, MS; Lin, FF; Lin, JS; Lin, MF; Van Bemmel, D1
Fukabori, Y; Masuda, H; Nakano, K; Shimizu, N; Yamanaka, H1
Eto, H; Gleave, ME; Hara, I; Miyake, H1
Cheskis, B; Mancini, MA; Marcelli, M; McPhaul, MJ; Nan, B; Sun, S; Unni, E1
Coetzee, GA; Jia, L1
van der Poel, HG1
Garrett, MD; Mantoni, TS; Reid, G1
Gu, RG; Ma, QZ; Zhou, CW1
Adams, H; Berger, R; Garraway, LA; Hahn, WC; Lin, DI; Loda, M; Nieto, M; Sicinska, E; Signoretti, S1
Angelucci, C; Iacopino, F; Lama, G; Sica, G1
Brodie, A; Guo, Z; Macedo, LF; Qiu, Y; Sabnis, GJ; Tilghman, SL1
Barker, S; Puddefoot, JR; Vinson, GP1
Hara, N; Labrie, F; Nishiyama, T; Suzuki, K; Takahashi, K; Yamana, K1
Beliakoff, J; Brooks, JD; Li, TH; Peng, Y; Sun, Z; Zhao, H1
Arasheben, A; Barski, A; Buchanan, G; Coetzee, GA; Cogan, JP; Frenkel, B; Gerald, WL; Jariwala, U; Jia, L; Pregizer, S; Prescott, J; Scher, HI; Tilley, WD1
Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Ricevuto, E; Ventura, L; Vicentini, C1
Cunningham, GR; Ittmann, M; Li, H; Shao, TC1
Mahajna, J; Nevo, E; Wasser, SP; Zaidman, BZ1
Cai, LQ; Imperato-McGinley, JL; Qiao, Y; Tan, C; Zhang, ZK; Zhu, YS1
Gudkov, AV; Gurova, KV; Krivokrisenko, V; Narizhneva, N; Tararova, ND1
Byrns, MC; Penning, TM; Steckelbroeck, S1
Chung, S; Honma, S; Nakagawa, H; Nakamura, Y; Okuyama, A; Tamura, K; Uemura, M1
Farmer, PB; Gescher, AJ; Greaves, P; Mellon, JK; Pathak, S; Sharma, RA; Singh, R; Steward, WP; Verschoyle, RD1
Bruckheimer, EM; Kyprianou, N; Partin, JV; Strup, SE; Zhu, ML1
Balk, SP; Bao, BY; Brown, M; Chuang, BF; Kantoff, PW; Lee, GS; Sartor, O; Wang, Q1
Marts, SA; Mukherji, S; Padilla, GM; Petrow, V1
Kodama, T; Shimazaki, J1
Albert, JD; Geller, J1
Hoppen, HO; Izbicki, JR; Izbicki, W; Schmitz, R; Troidl, H1
Murayama, Y1
Albert, JD; de la Vega, DJ; Geller, J; Nachtsheim, DA1
Hamada, Y; Matsui, K; Nomura, Y; Saeki, K; Tashiro, H1
Fujii, H1
Fricks, CM; Mehta, RG; Moon, RC1
Korsten, CB; Persijn, JP; Rümke, P1
French, FS; Lea, OA1
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gatto, V; Leonardi, L1
Akimoto, S; Ichikawa, T; Shimazaki, J1
Barnard, J; Brass, AL; Patai, BL; Rukstalis, DB; Salvi, D1
Geller, J1
Brawley, OW; Ford, LG; Kramer, BS; Perlman, JA; Thompson, I1
Beck, S; Filmer, A; Hackenberg, R; Hushmand Nia, A; Koch, M; Kunzmann, R; Schulz, KD; Slater, EP1
Jones, RE; Loop, S; Meikle, AW; Ostenson, RC; Plymate, SR; Tuttle, RM1
Casamento, JB; Cockett, AT; Iwamura, M; Sluss, PM1
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L1
Feldman, D; Ly, LH; Peehl, DM; Zhao, XY1
Beaulieu, M; Bélanger, A; Guillemette, C; Hum, DW; Lévesque, E1
Labrie, C; Pouliot, F1
Cox, ME; Deeble, PD; Lakhani, S; Parsons, SJ1
Bell, DA; Lunn, RM; Mohler, JL; Taylor, JA1
Leung, LK; Wang, TT1
Becker, M; Cato, AC; Klocker, H; Mink, S; Peterziel, H; Schonert, A1
Hida, N; Labrie, F; Poulin, R; Veilleux, R1
Balczon, R; Chakrabarti, A; Hueser, CN; Ripple, M; Schatten, H; Taylor, M; Weindruch, R1
Heemers, H; Heyns, W; Swinnen, JV; Vanderhoydonc, F; Verhoeven, G1
Jeanteur, P1
Brown, GM; Pang, SF; Shiu, SY; Tam, PC; Xi, SC1
Ford, OH; French, FS; Gregory, CW; He, B; Johnson, RT; Mohler, JL; Wilson, EM1
Albert, J; de la Vega, D; Geller, J; Loza, D; Stoeltzing, W1
André, J; Garcia, M; Humeau, C; Rochefort, H; Vic, P1
Ascoli, M; Lacroix, A; McKenna, TJ; Puett, D1
Jellinghaus, W; Schroeder, FH1
Alford, TC; Do, HM; Geelhoed, GW; Lippman, ME; Tsangaris, NT1
King, RJ; Yates, J1
Baroni, M; Borsellino, G; Buonaguidi, A; Elli, G; Mondina, R; Poma, S; Rescalli, S; Sonato, A1
Fukabori, Y; McKeehan, WL; Nikolaropoulos, S; Wang, F; Yan, G1
Bellward, GD; Emerman, JT; Rowse, GJ; Weinberg, J1
Frei, E; Kantoff, PW; LeBlanc, GA; Ng, SF; Waxman, DJ1
Bohlken, S; Dijkstra, I; Geldof, AA; Meulenbroek, MF; Rao, BR1
Furuya, Y; Sato, N; Shimazaki, J; Watabe, Y1
de Jong, FH; Moerings, EP; Schröder, FH; van Kreuningen, A; van Steenbrugge, GJ; van Weerden, WM1
Robel, P1
Bruun, E; Frandsen, H; Frimodt-Møller, C; Nielsen, K; Rasmussen, LB; Vinnergaard, T1
Tohjoh, S1
Forbes, A; Iqbal, MJ; Johnson, PJ; Wilkinson, ML; Williams, R1
Bressel, M; Kastendieck, H; Klein, H; Voigt, KD1
Canellos, GP1
Crum, A; Handelsman, DJ; Peterson, M; Rajfer, J; Steiner, B; Swerdloff, RS1
Heston, WD; Kadmon, D1
Schröder, FH; van Steenbrugge, GJ1
Bell, C; Chang, SM; Chung, LW; Ro, JY; von Eschenbach, AC; Zhau, H1
Petrow, V1
Andriole, GL; Kish, ML; Linehan, WM; Loriaux, DL; Rittmaster, RS1
Mauvais-Jarvis, P; Mowszowicz, I; Portois, MC; Santen, RJ1
Kitamura, Y; Matsumoto, K; Nakamura, N; Nishizawa, Y; Noguchi, S; Sato, B; Uchida, N; Yamaguchi, K1

Reviews

10 review(s) available for dihydrotestosterone and Hormone-Dependent Neoplasms

ArticleYear
[Dual effects of androgens on mammary gland].
    Bulletin du cancer, 2008, Volume: 95, Issue:5

    Topics: Age Factors; Androgen Antagonists; Androgens; Breast Neoplasms; Cell Proliferation; Dihydrotestosterone; Estradiol; Estrogens; Female; Humans; Mammary Glands, Human; Neoplasms, Hormone-Dependent; Polymorphism, Genetic; Receptors, Androgen; Receptors, Estrogen; Signal Transduction

2008
Molecular profiles of finasteride effects on prostate carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:6

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgens; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azasteroids; Dihydrotestosterone; Disease Progression; Dutasteride; Epithelial Cells; Finasteride; Humans; Isoenzymes; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Patient Selection; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Stromal Cells

2009
[The alternative androgen synthesis pathway in humans].
    Klinische Padiatrie, 2013, Volume: 225, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Androstenedione; Animals; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Infant; Infant, Newborn; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Pregnancy; Prostatic Neoplasms; Sex Differentiation; Steroid 21-Hydroxylase; Testis; Testosterone

2013
Trilostane in advanced breast cancer.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:17

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Hormone-Dependent; Postmenopause; Rats

2006
[Recent findings on androgen receptors].
    Nihon rinsho. Japanese journal of clinical medicine, 1981, Volume: 39, Issue:9

    Topics: Animals; Cell Nucleus; Cytosol; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid; RNA

1981
Endocrine therapy: predictors of response to prostatic cancer.
    Seminars in urology, 1983, Volume: 1, Issue:4

    Topics: Androgen Antagonists; Cell Nucleus; Cytosol; Dihydrotestosterone; Humans; Male; Neoplasm Staging; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen

1983
5-Alpha-reductase inhibition and prostate cancer prevention.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1994, Volume: 3, Issue:2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Cell Transformation, Neoplastic; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Risk Factors; Survival Rate

1994
EB 33, an epithelial cell line from human prostate carcinoma: a review.
    National Cancer Institute monograph, 1978, Issue:49

    Topics: Acid Phosphatase; Animals; Cell Line; Chromosome Aberrations; Dihydrotestosterone; Epithelium; Glucosephosphate Dehydrogenase; Humans; Immunity; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Transplantation, Heterologous

1978
Plasma steroid transport in subjects with tumors of hormonal target organs: a review.
    Tumori, 1992, Jun-30, Volume: 78, Issue:3

    Topics: Breast Neoplasms; Dihydrotestosterone; Endometrial Neoplasms; Estradiol; Female; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Sex Hormone-Binding Globulin

1992
The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications.
    The Prostate, 1986, Volume: 9, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Animals; Dihydrotestosterone; Humans; Male; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Prostate; Prostatic Neoplasms; Rats; Testosterone

1986

Trials

1 trial(s) available for dihydrotestosterone and Hormone-Dependent Neoplasms

ArticleYear
Serum testosterone and dihydrotestosterone and prostate cancer risk in the placebo arm of the Reduction by Dutasteride of Prostate Cancer Events trial.
    European urology, 2012, Volume: 62, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Aged; Antineoplastic Agents, Hormonal; Azasteroids; Biopsy; Dihydrotestosterone; Double-Blind Method; Dutasteride; Humans; Kallikreins; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Grading; Neoplasms, Hormone-Dependent; Odds Ratio; Placebos; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design; Testosterone; Time Factors; Treatment Outcome; Up-Regulation

2012

Other Studies

112 other study(ies) available for dihydrotestosterone and Hormone-Dependent Neoplasms

ArticleYear
P-glycoprotein increases the efflux of the androgen dihydrotestosterone and reduces androgen responsive gene activity in prostate tumor cells.
    The Prostate, 2004, Apr-01, Volume: 59, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Northern; Blotting, Western; Cyclosporins; Dihydrotestosterone; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Male; Neoplasms, Hormone-Dependent; Precipitin Tests; Prostatic Neoplasms; Receptors, Androgen; RNA, Neoplasm; Verapamil

2004
Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents.
    Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13

    Topics: Androgen Antagonists; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Drug Design; Drug Screening Assays, Antitumor; Genes, Reporter; Humans; Luciferases; Male; Mutation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship; Transcriptional Activation; Transfection

2006
Associations between sun sensitive pigmentary genes and serum prostate specific antigen levels.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Androgens; Australia; Dihydrotestosterone; Europe; Genes, Neoplasm; Genetic Predisposition to Disease; Humans; Male; Melanoma; Models, Genetic; Neoplasms, Hormone-Dependent; Neoplasms, Radiation-Induced; New Zealand; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Tolerance; Reference Values; Skin Neoplasms; Skin Pigmentation; Sunlight; Testosterone

2018
Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism.
    The Journal of steroid biochemistry and molecular biology, 2018, Volume: 183

    Topics: Aromatase Inhibitors; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Drug Therapy, Combination; Estradiol; Estradiol Dehydrogenases; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Hormone-Dependent; Steryl-Sulfatase; Sulfonic Acids; Tumor Cells, Cultured

2018
Dihydrotestosterone and bicalutamide do not affect periostin expression in androgen-dependent LNCaP prostate cancer cell lines.
    Anticancer research, 2013, Volume: 33, Issue:3

    Topics: Androgens; Anilides; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; RNA, Messenger; Tosyl Compounds

2013
Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer.
    Endocrine-related cancer, 2014, Volume: 21, Issue:3

    Topics: Androgens; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Dihydrotestosterone; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Immunoenzyme Techniques; Male; MicroRNAs; Neoplasms, Hormone-Dependent; Prostatic Hyperplasia; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Wound Healing; Zinc Finger E-box Binding Homeobox 2

2014
Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Nov-18, Volume: 111, Issue:46

    Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Animals, Congenic; Azoxymethane; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Genes, APC; Gonadal Steroid Hormones; Hormone Replacement Therapy; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mutation; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Specificity; Ovariectomy; Postmenopause; Random Allocation; Rats; Rats, Inbred F344; Rats, Mutant Strains; Receptors, Androgen; RNA, Messenger; Sex Distribution; Species Specificity

2014
Colorectal cancer: male hormones increase the incidence of colonic adenomas.
    Nature reviews. Gastroenterology & hepatology, 2015, Volume: 12, Issue:1

    Topics: Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Male; Neoplasms, Hormone-Dependent

2015
Effects of treatment with androgen receptor ligands on microRNA expression of prostate cancer cells.
    Toxicology, 2015, Jul-03, Volume: 333

    Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Ligands; Male; MicroRNAs; Nandrolone; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate-Specific Antigen; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Time Factors; Tosyl Compounds

2015
Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells.
    Cancer research, 2016, Jan-15, Volume: 76, Issue:2

    Topics: Animals; Cell Line, Tumor; Cyclin D1; Dihydrotestosterone; DNA Damage; DNA Repair; Histones; Humans; Male; Mice; Mice, Knockout; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Transfection

2016
Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer.
    Oncogene, 2008, Dec-04, Volume: 27, Issue:57

    Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Drug Delivery Systems; Estradiol; Estrogen Receptor alpha; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Receptors, Androgen; Receptors, Steroid; Recombinant Fusion Proteins; Ubiquitination

2008
Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo.
    The Prostate, 2009, May-15, Volume: 69, Issue:7

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Dihydrotestosterone; Docetaxel; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nevirapine; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Reverse Transcriptase Inhibitors; RNA, Neoplasm; Signal Transduction; Taxoids; Tosyl Compounds; Xenograft Model Antitumor Assays

2009
Id-1 expression in androgen-dependent prostate cancer is negatively regulated by androgen through androgen receptor.
    Cancer letters, 2009, Jun-18, Volume: 278, Issue:2

    Topics: Androgens; Cell Line, Tumor; Dihydrotestosterone; Humans; Inhibitor of Differentiation Protein 1; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger

2009
Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels.
    Cancer research, 2009, Mar-15, Volume: 69, Issue:6

    Topics: Androgens; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Humans; Hyaluronic Acid; Male; Metribolone; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Uridine Diphosphate Glucose Dehydrogenase; Uridine Diphosphate Glucuronic Acid

2009
The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines.
    Cancer research, 2009, Apr-15, Volume: 69, Issue:8

    Topics: Androgens; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Gene Expression; Humans; Male; MicroRNAs; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Transfection

2009
Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines.
    Endocrine-related cancer, 2010, Volume: 17, Issue:4

    Topics: Binding Sites; Cell Line, Tumor; Chromatin Immunoprecipitation; Dihydrotestosterone; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasms, Hormone-Dependent; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger

2010
The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
    Experimental cell research, 2010, Dec-10, Volume: 316, Issue:20

    Topics: Androgen-Binding Protein; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Gene Expression; Genes, Reporter; Humans; Hypoglycemic Agents; Male; Mutation; Neoplasms, Hormone-Dependent; PPAR gamma; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Transfection

2010
Androgen regulation of micro-RNAs in prostate cancer.
    The Prostate, 2011, Volume: 71, Issue:6

    Topics: Androgens; Animals; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; MicroRNAs; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transfection; Transplantation, Heterologous

2011
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
    Environmental research, 2011, Volume: 111, Issue:3

    Topics: Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Humans; Hydrocarbons, Chlorinated; Neoplasms, Hormone-Dependent; Receptors, Androgen; Regression Analysis

2011
Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide.
    Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11, Issue:6

    Topics: Androgen Antagonists; Androgens; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2010
Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer.
    Gynecologic oncology, 2012, Volume: 124, Issue:1

    Topics: Androgens; Ascitic Fluid; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cystadenocarcinoma, Serous; Dihydrotestosterone; Exons; Female; Humans; Immunohistochemistry; Neoplasm Grading; Neoplasms, Glandular and Epithelial; Neoplasms, Hormone-Dependent; Ovarian Neoplasms; Receptors, Androgen; RNA, Messenger; S Phase; Stimulation, Chemical; Trinucleotide Repeats; Tumor Cells, Cultured

2012
Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells.
    International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6

    Topics: Adult; Anilides; Cell Line, Tumor; Cell Proliferation; Cinnamates; Dihydrotestosterone; Hedgehog Proteins; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Veratrum Alkaloids

2012
Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Androgens; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Genes, Dominant; Humans; Immunoblotting; Male; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Transcriptional Activation; Transplantation, Heterologous; Tumor Burden

2012
Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells.
    Urology, 2012, Volume: 79, Issue:2

    Topics: Adenocarcinoma; Androgens; Cell Line; Cell Line, Tumor; Culture Media; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dihydrotestosterone; Down-Regulation; Enzyme Induction; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Sulfide; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Receptors, Androgen; Stromal Cells

2012
Dihydrotestosterone synthesis from adrenal precursors does not involve testosterone in castration-resistant prostate cancer.
    Cancer biology & therapy, 2012, Volume: 13, Issue:5

    Topics: Dihydrotestosterone; Disease Progression; Humans; Male; Molecular Targeted Therapy; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Testosterone

2012
Goodbye androgen hypothesis, hello saturation model.
    European urology, 2012, Volume: 62, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Antineoplastic Agents, Hormonal; Azasteroids; Dihydrotestosterone; Dutasteride; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Testosterone

2012
Expression changes and regulation of AR and IGF-1 in PC3 prostate cancer cells treated with sexual hormones and flutamide.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:6

    Topics: Androgen Antagonists; Androgens; Blotting, Western; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptors, Androgen; Signal Transduction; Tumor Cells, Cultured

2012
Liprin-alpha2 gene, protein tyrosine phosphatase LAR interacting protein related gene, is downregulated by androgens in the human prostate cancer cell line LNCaP.
    International journal of molecular medicine, 2002, Volume: 10, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Androgens; Cycloheximide; Dihydrotestosterone; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Proteins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

2002
Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components.
    The Prostate, 2002, Oct-01, Volume: 53, Issue:2

    Topics: Animals; Apoptosis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dihydrotestosterone; Glycine max; Humans; Isoflavones; Lung Neoplasms; Lymph Nodes; Male; Mice; Mice, SCID; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Plant Extracts; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Soybean Proteins; Specific Pathogen-Free Organisms; Testosterone; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2002
Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells.
    Cancer letters, 2003, Jan-10, Volume: 189, Issue:1

    Topics: Adenocarcinoma; Cell Division; Dihydrotestosterone; Eicosanoic Acids; Flow Cytometry; gamma-Linolenic Acid; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2003
A novel human prostate-specific gene-1 (HPG-1): molecular cloning, sequencing, and its potential involvement in prostate carcinogenesis.
    Cancer research, 2003, Jan-15, Volume: 63, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Cell Adhesion Molecules; Cell Division; Cloning, Molecular; Dihydrotestosterone; DNA, Complementary; Humans; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Polymerase Chain Reaction; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation

2003
Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells.
    The Journal of urology, 2003, Volume: 169, Issue:4

    Topics: Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Up-Regulation

2003
Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.
    The Journal of urology, 2003, Volume: 170, Issue:5

    Topics: Androgen Antagonists; Anilides; Autocrine Communication; BCG Vaccine; Carcinoma, Transitional Cell; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Genes, Reporter; Humans; Neoplasms, Hormone-Dependent; NF-kappa B; Nitriles; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vaccines, Attenuated

2003
Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells.
    Cancer research, 2003, Nov-01, Volume: 63, Issue:21

    Topics: Androgens; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Dihydrotestosterone; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; NF-kappa B; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transfection

2003
p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas.
    International journal of cancer, 2004, Feb-20, Volume: 108, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Breast Neoplasms; Cell Division; Dihydrotestosterone; Estrogens; Humans; Male; Neoplasms, Hormone-Dependent; Phosphorylation; Prostate; Prostatic Neoplasms; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Testicular Neoplasms; Tumor Cells, Cultured; Up-Regulation

2004
Expression of bone morphogenetic protein-7 (BMP-7) in human prostate.
    The Prostate, 2004, Apr-01, Volume: 59, Issue:1

    Topics: Aged; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta

2004
Protection of androgen-dependent human prostate cancer cells from oxidative stress-induced DNA damage by overexpression of clusterin and its modulation by androgen.
    The Prostate, 2004, Dec-01, Volume: 61, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Androgens; Apoptosis; Clusterin; Deoxyguanosine; Dihydrotestosterone; DNA Damage; DNA, Complementary; Gene Expression; Glycoproteins; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Molecular Chaperones; Neoplasms, Hormone-Dependent; Oxidative Stress; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured

2004
Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.
    Cancer research, 2004, Oct-01, Volume: 64, Issue:19

    Topics: Activating Transcription Factor 1; Anilides; Animals; Cell Line, Tumor; Co-Repressor Proteins; Dihydrotestosterone; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; src-Family Kinases; Tosyl Compounds; Trans-Activators; Transcription Factors

2004
Androgen receptor-dependent PSA expression in androgen-independent prostate cancer cells does not involve androgen receptor occupancy of the PSA locus.
    Cancer research, 2005, Sep-01, Volume: 65, Issue:17

    Topics: Cell Line, Tumor; Chromatin Immunoprecipitation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Androgen; RNA, Messenger; Transfection

2005
Androgen receptor and TGFbeta1/Smad signaling are mutually inhibitory in prostate cancer.
    European urology, 2005, Volume: 48, Issue:6

    Topics: Apoptosis; Dihydrotestosterone; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Up-Regulation

2005
Androgen receptor activity is inhibited in response to genotoxic agents in a p53-independent manner.
    Oncogene, 2006, May-25, Volume: 25, Issue:22

    Topics: Androgen Receptor Antagonists; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Chromatin Immunoprecipitation; Cisplatin; Dihydrotestosterone; Etoposide; Humans; Ligands; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Subcellular Fractions; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2006
[Effect of dihydrotestosterone on the transcriptions and expressions of Smad3 and Smad4 in LNCaP cell line].
    Zhonghua nan ke xue = National journal of andrology, 2006, Volume: 12, Issue:3

    Topics: Androgens; Cell Line, Tumor; Dihydrotestosterone; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad4 Protein; Transcription, Genetic

2006
Androgen-dependent regulation of Her-2/neu in prostate cancer cells.
    Cancer research, 2006, Jun-01, Volume: 66, Issue:11

    Topics: Androgen Receptor Antagonists; Androgens; Animals; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Mice; Neoplasms, Hormone-Dependent; Phosphorylation; Prostatic Neoplasms; Receptor, ErbB-2; Receptors, Androgen; RNA, Messenger; RNA, Small Interfering; Transfection

2006
Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells.
    International journal of oncology, 2006, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Leuprolide; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms, Hormone-Dependent; Phosphorylation; Prostatic Neoplasms; Protein Kinase Inhibitors; Quinazolines; Time Factors; Tyrphostins

2006
Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole.
    Cancer research, 2006, Aug-01, Volume: 66, Issue:15

    Topics: Androgen Receptor Antagonists; Androgens; Androstenedione; Aromatase; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; RNA, Small Interfering; Transfection; Triazoles

2006
Importance of the intracrine metabolism of adrenal androgens in androgen-dependent prostate cancer.
    Prostate cancer and prostatic diseases, 2007, Volume: 10, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Glands; Androgens; Cell Line, Tumor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction

2007
A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells.
    Nucleic acids research, 2007, Volume: 35, Issue:8

    Topics: Adenoviridae; Androgen Receptor Antagonists; Androgens; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Down-Regulation; Gene Expression Regulation; Male; Mice; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Transcriptional Activation; Xenograft Model Antitumor Assays

2007
Identification of novel androgen receptor target genes in prostate cancer.
    Molecular cancer, 2007, Jun-06, Volume: 6

    Topics: Adenocarcinoma; Androgens; Binding Sites; Cell Adhesion Molecules; Cell Line, Tumor; Chromosomes, Human; delta-1-Pyrroline-5-Carboxylate Reductase; Dihydrotestosterone; Extracellular Matrix Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Intracellular Signaling Peptides and Proteins; Male; Mucin-6; Mucins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Ornithine-Oxo-Acid Transaminase; Prostatic Neoplasms; Protein Kinase C-delta; Pyrroline Carboxylate Reductases; Receptors, Androgen; Transcription, Genetic; TRPV Cation Channels

2007
In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma.
    The Prostate, 2007, Sep-01, Volume: 67, Issue:12

    Topics: Adult; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents; Blotting, Western; Carbazoles; Carcinoma; Cell Line, Tumor; Cohort Studies; Dihydrotestosterone; Furans; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Tosyl Compounds

2007
Effects of dutasteride on prostate growth in the large probasin-large T antigen mouse model of prostate cancer.
    The Journal of urology, 2007, Volume: 178, Issue:4 Pt 1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Animals; Antigens, Viral, Tumor; Apoptosis; Azasteroids; Cell Division; Cell Transformation, Neoplastic; Dihydrotestosterone; Disease Models, Animal; Dutasteride; Enzyme Inhibitors; Female; Male; Membrane Proteins; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Seminal Vesicles; Transgenes

2007
Androgen receptor-dependent and -independent mechanisms mediate Ganoderma lucidum activities in LNCaP prostate cancer cells.
    International journal of oncology, 2007, Volume: 31, Issue:4

    Topics: Annexin A5; Apoptosis; Caspase 3; Caspase 8; Cell Proliferation; Cyclin D; Cyclins; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasms, Hormone-Dependent; Plant Extracts; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Receptors, Androgen; Reishi; Tumor Cells, Cultured

2007
17alpha-estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals.
    The Prostate, 2007, Dec-01, Volume: 67, Issue:16

    Topics: Animals; Blotting, Western; Cell Growth Processes; Cell Line, Tumor; Cyclin A; Cyclin D1; Dihydrotestosterone; Estradiol; Gene Expression; Humans; Male; Mice; Mice, SCID; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stereoisomerism; Xenograft Model Antitumor Assays

2007
Prostate cancer cells tolerate a narrow range of androgen receptor expression and activity.
    The Prostate, 2007, Dec-01, Volume: 67, Issue:16

    Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription, Genetic; Transfection

2007
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone indepe
    Biochemical pharmacology, 2008, Jan-15, Volume: 75, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Catalysis; Dihydrotestosterone; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Indoles; Indomethacin; Melatonin; Neoplasms, Hormone-Dependent; Oxidation-Reduction; Phenanthrenes

2008
Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.
    Cancer science, 2008, Volume: 99, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Cell Growth Processes; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; RNA, Small Interfering; Testosterone; Transfection

2008
Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo.
    Cancer letters, 2008, Mar-08, Volume: 261, Issue:1

    Topics: Androgens; Animals; Cell Line, Tumor; Dihydrotestosterone; DNA Adducts; DNA Damage; Flutamide; Humans; Male; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reactive Oxygen Species

2008
TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells.
    The Prostate, 2008, Feb-15, Volume: 68, Issue:3

    Topics: Androgen-Binding Protein; Apoptosis; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Drug Synergism; Humans; Luciferases; Male; Microscopy, Fluorescence; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Androgen; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad4 Protein; Transcriptional Activation; Transfection; Transforming Growth Factor beta

2008
Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.
    The Prostate, 2008, Jun-01, Volume: 68, Issue:8

    Topics: Androgen Receptor Antagonists; Cell Line, Tumor; Dihydrotestosterone; Down-Regulation; Gene Expression; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Humans; Male; Minor Histocompatibility Antigens; Neoplasms, Hormone-Dependent; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; RNA Interference

2008
Endocrine dependence of prostatic cancer upon dihydrotestosterone and not upon testosterone.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:5

    Topics: Adenocarcinoma; Animals; Cells, Cultured; Dihydrotestosterone; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Progesterone; Prostatic Neoplasms; Rats; Testosterone

1984
Effects of steroid hormone therapy on primarily xenotransplanted human colorectal adenocarcinomas.
    Journal of cancer research and clinical oncology, 1984, Volume: 108, Issue:3

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dihydrotestosterone; Estradiol; Female; Hormones; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Progesterone; Receptors, Estrogen; Receptors, Progesterone; Rectal Neoplasms; Transplantation, Heterologous

1984
Plasma sex hormone-binding globulin (SHBG) and obesity in breast cancer patients.
    Cancer detection and prevention, 1983, Volume: 6, Issue:4-5

    Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Mastectomy; Neoplasms, Hormone-Dependent; Obesity; Risk; Sex Hormone-Binding Globulin

1983
Tissue dihydrotestosterone levels and clinical response to hormonal therapy in patients with advanced prostate cancer.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:1

    Topics: Androgen Antagonists; Cell Nucleus; Cytosol; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen

1984
[Evaluation of steroid hormone sensitivity of human breast cancer cells in culture (MCF-7) by a colony formation method].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:5

    Topics: Breast Neoplasms; Cells, Cultured; Colony-Forming Units Assay; Dihydrotestosterone; Estradiol; Female; Humans; Neoplasms, Hormone-Dependent; Progesterone

1983
[Histological and endocrinological studies on prostatic carcinoma (author's transl)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1981, Volume: 72, Issue:11

    Topics: Aged; Biotransformation; Dihydrotestosterone; Histocytochemistry; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Testosterone

1981
Androgen receptors in chemically-induced colon carcinogenesis.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Animals; Castration; Colonic Neoplasms; Dihydrotestosterone; Dimethylhydrazines; Female; Male; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Ovary; Rats; Receptors, Androgen; Receptors, Steroid; Testis

1980
Oestrogen and androgen receptors in melanoma.
    British journal of cancer, 1980, Volume: 41, Issue:4

    Topics: Adult; Aged; Dihydrotestosterone; Estradiol; Female; Humans; Male; Melanoma; Middle Aged; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid

1980
Androgen receptor protein in the androgen-dependent Dunning R-3327 prostate carcinoma.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Animals; Castration; Cytosol; Dihydrotestosterone; Kinetics; Male; Molecular Weight; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid; Testosterone

1981
Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Flutamide; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tumor Cells, Cultured

1995
An inhibitory effect of TZP-4238 on the growth of androgen-sensitive rat prostatic tumor (Dunning R3327).
    Endocrine journal, 1993, Volume: 40, Issue:4

    Topics: Administration, Oral; Androgen Antagonists; Androgens; Animals; Chlormadinone Acetate; Dihydrotestosterone; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Size; Prostate; Prostatic Neoplasms; Rats; Testis; Testosterone

1993
Androgen up-regulates epidermal growth factor receptor expression and binding affinity in PC3 cell lines expressing the human androgen receptor.
    Cancer research, 1995, Jul-15, Volume: 55, Issue:14

    Topics: Adenocarcinoma; Androgens; Animals; Bone Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Mice; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Stimulation, Chemical; Transforming Growth Factor alpha; Tumor Cells, Cultured; Up-Regulation

1995
Basis for hormonal management of advanced prostate cancer.
    Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl

    Topics: Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Biosynthesis; Rats; Testosterone

1993
Androgen responsiveness of the new human endometrial cancer cell line MFE-296.
    International journal of cancer, 1994, Apr-01, Volume: 57, Issue:1

    Topics: Androgens; Animals; Base Sequence; Cell Division; Dihydrotestosterone; DNA, Neoplasm; Endometrial Neoplasms; Female; Humans; Karyotyping; Mice; Mice, Nude; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Phenotype; Progestins; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Transfection; Tumor Cells, Cultured

1994
Effect of 5-alpha-reductase inhibition and dexamethasone administration on the growth characteristics and intratumor androgen levels of the human prostate cancer cell line PC-3.
    The Prostate, 1994, Volume: 24, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Animals; Azasteroids; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Random Allocation; Testosterone; Tumor Cells, Cultured

1994
Insulin-like growth factor I: action and receptor characterization in human prostate cancer cell lines.
    The Prostate, 1993, Volume: 22, Issue:3

    Topics: Binding, Competitive; Cell Division; Culture Media, Serum-Free; Dihydrotestosterone; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptor, IGF Type 1; Tumor Cells, Cultured

1993
Indirect growth inhibition of the MDA-MB-231 hormone-independent breast cancer cell line by dihydrotestosterone.
    Annals of the New York Academy of Sciences, 1996, Apr-30, Volume: 784

    Topics: Breast Neoplasms; Cell Division; Dihydrotestosterone; Female; Humans; Neoplasms, Hormone-Dependent; Receptors, Androgen; Tumor Cells, Cultured

1996
1alpha,25-dihydroxyvitamin D3 actions in LNCaP human prostate cancer cells are androgen-dependent.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Analysis of Variance; Androgen Antagonists; Androgens; Anilides; Blotting, Northern; Blotting, Western; Calcitriol; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tritium; Tumor Cells, Cultured; Up-Regulation

1997
Effect of fibroblastic growth factors (FGF) on steroid UDP-glucuronosyltransferase expression and activity in the LNCaP cell line.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 64, Issue:1-2

    Topics: Androgens; Cell Division; Dihydrotestosterone; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Gene Expression; Glucuronates; Glucuronosyltransferase; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Steroids; Tumor Cells, Cultured

1998
Expression profile of agonistic Smads in human breast cancer cells: absence of regulation by estrogens.
    International journal of cancer, 1999, Mar-31, Volume: 81, Issue:1

    Topics: Breast Neoplasms; Dihydrotestosterone; DNA-Binding Proteins; Estrogens; Humans; Neoplasms, Hormone-Dependent; RNA, Messenger; Smad2 Protein; Smad3 Protein; Smad4 Protein; Trans-Activators; Transforming Growth Factor beta; Tumor Cells, Cultured

1999
Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression.
    Cancer research, 1999, Aug-01, Volume: 59, Issue:15

    Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Androgens; Biomarkers; Bombesin; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Lineage; Chromogranin A; Chromogranins; Colforsin; Cyclic AMP; Cytoplasmic Granules; Dihydrotestosterone; Disease Progression; Epinephrine; Humans; Isoproterenol; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neoplastic Stem Cells; Neuroendocrine Tumors; Neurotensin; Parathyroid Hormone-Related Protein; Phenotype; Phosphopyruvate Hydratase; Prostatic Neoplasms; Protein-Tyrosine Kinases; Proteins; Second Messenger Systems; Serotonin; Tumor Cells, Cultured

1999
Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2).
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenocarcinoma; Asian People; Black People; Case-Control Studies; Dihydrotestosterone; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Isoenzymes; Male; Neoplasms, Hormone-Dependent; North Carolina; Odds Ratio; Polymorphism, Genetic; Prostatic Neoplasms; Risk; Steroid 17-alpha-Hydroxylase; Taiwan; Testosterone; White People

1999
Paradoxical regulation of Bcl-2 family proteins by 17beta-oestradiol in human breast cancer cells MCF-7.
    British journal of cancer, 1999, Volume: 81, Issue:3

    Topics: Adenocarcinoma; Apoptosis; bcl-X Protein; Breast Neoplasms; Cell Count; Dihydrotestosterone; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Tamoxifen

1999
Rapid signalling by androgen receptor in prostate cancer cells.
    Oncogene, 1999, Nov-04, Volume: 18, Issue:46

    Topics: Adenocarcinoma; Androgen Antagonists; Cell Nucleus; Cytoplasm; Dihydrotestosterone; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Ligands; Male; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptors, Androgen; Recombinant Fusion Proteins; Testosterone; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured

1999
Differential androgen sensitivity is associated with clonal heterogeneity in steroid metabolism, ornithine decarboxylase regulation and IL-1alpha action in mouse mammary tumor cells.
    The Journal of steroid biochemistry and molecular biology, 1999, Volume: 71, Issue:1-2

    Topics: Androgens; Androstenediol; Androstenedione; Animals; Binding Sites; Cell Division; Clone Cells; Dehydroepiandrosterone; Dihydrotestosterone; Interleukin-1; Male; Mammary Neoplasms, Experimental; Mice; Mitogens; Neoplasms, Hormone-Dependent; Ornithine Decarboxylase; Steroids; Testosterone; Tumor Cells, Cultured

1999
Androgen and taxol cause cell type-specific alterations of centrosome and DNA organization in androgen-responsive LNCaP and androgen-independent DU145 prostate cancer cells.
    Journal of cellular biochemistry, 2000, Volume: 76, Issue:3

    Topics: Androgens; Antineoplastic Agents, Phytogenic; Cell Division; Centrosome; Dihydrotestosterone; DNA, Neoplasm; Humans; Male; Metribolone; Microscopy, Electron; Microscopy, Fluorescence; Neoplasms, Hormone-Dependent; Paclitaxel; Prostatic Neoplasms; Testosterone Congeners

2000
Progestins and androgens increase expression of Spot 14 in T47-D breast tumor cells.
    Biochemical and biophysical research communications, 2000, Mar-05, Volume: 269, Issue:1

    Topics: Breast Neoplasms; Chromosomes, Human, Pair 11; Dihydrotestosterone; Female; Gene Expression; Humans; Lipids; Metribolone; Neoplasms, Hormone-Dependent; Nuclear Proteins; Pregnenediones; Progesterone; Progesterone Congeners; Proteins; Testosterone Congeners; Transcription Factors; Tumor Cells, Cultured

2000
[Perhaps an explanation for the therapeutic escape of prostate cancer treated with antiandrogens].
    Bulletin du cancer, 2000, Volume: 87, Issue:7-8

    Topics: Androgen Antagonists; Dihydrotestosterone; Drug Resistance, Neoplasm; Humans; Hydrocortisone; Male; Neoplasms, Hormone-Dependent; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Tumor Cells, Cultured; X Chromosome

2000
Potential involvement of mt1 receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells.
    Journal of pineal research, 2000, Volume: 29, Issue:3

    Topics: Adenocarcinoma; Blotting, Western; Calcium; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Humans; Immunoenzyme Techniques; Male; Melatonin; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2000
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy.
    Cancer research, 2001, Jun-01, Volume: 61, Issue:11

    Topics: Aged; Androgen Antagonists; Animals; Dihydrotestosterone; Histone Acetyltransferases; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivator 2; Orchiectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Transcription Factors; Transcriptional Activation; Transplantation, Heterologous

2001
Dihydrotestosterone concentration in prostate cancer tissue as a predictor of tumor differentiation and hormonal dependency.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Cell Differentiation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid

1978
[Early effect of estradiol on ultrastructure of chromatin in the endometrium and hormone-dependent mammary tumors].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1978, Jul-17, Volume: 287, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Chromatin; Dihydrotestosterone; Endometrium; Estradiol; Female; Heterochromatin; In Vitro Techniques; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Rats; Receptors, Estrogen; Sheep; Tamoxifen; Time Factors

1978
Steroidogenesis in HCG-responsive Leydig cell tumor variants.
    Journal of steroid biochemistry, 1979, Volume: 10, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Chorionic Gonadotropin; Dihydrotestosterone; Hydroxyprogesterones; Leydig Cell Tumor; Male; Mice; Neoplasms, Hormone-Dependent; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone

1979
Steroid hormone receptors in human colon cancers.
    Cancer, 1979, Volume: 43, Issue:3

    Topics: Breast Neoplasms; Colonic Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Steroid

1979
Multiple sensitivities of mammary tumor cells in culture.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 2

    Topics: Animals; Cell Count; Cell Division; Cell Line; Culture Media; Dexamethasone; Dihydrotestosterone; Drug Resistance; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Testosterone

1978
Heparin-binding keratinocyte growth factor is a candidate stromal-to-epithelial-cell andromedin.
    Molecular endocrinology (Baltimore, Md.), 1992, Volume: 6, Issue:12

    Topics: Animals; Base Sequence; Cell Division; Cells, Cultured; Connective Tissue; Connective Tissue Cells; Dihydrotestosterone; Epithelial Cells; Epithelium; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Growth Substances; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Protein-Tyrosine Kinases; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Testosterone; Tumor Cells, Cultured

1992
Endocrine mediation of psychosocial stressor effects on mouse mammary tumor growth.
    Cancer letters, 1992, Jul-31, Volume: 65, Issue:1

    Topics: Analysis of Variance; Animals; Cell Division; Corticosterone; Dihydrotestosterone; Hydrocortisone; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Glucocorticoid; Stress, Psychological; Testosterone; Tumor Cells, Cultured

1992
Hormonal perturbations in patients with testicular cancer treated with cisplatin.
    Cancer, 1992, May-01, Volume: 69, Issue:9

    Topics: Adult; Androstenedione; Chorionic Gonadotropin; Cisplatin; Dihydrotestosterone; Estradiol; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Neoplasms, Hormone-Dependent; Testicular Neoplasms; Testosterone

1992
Consideration of the use of 17 beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5- alpha-androstan-3-one (4MA), a 5 alpha-reductase inhibitor, in prostate cancer therapy.
    Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Animals; Azasteroids; Cell Division; Cell Survival; Dihydrotestosterone; Female; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Organ Size; Prostate; Prostatic Neoplasms; Rats; Steroids

1992
Effects of estrogen on growth of androgen-responsive rat prostatic tumor (R 3327).
    Endocrinologia japonica, 1991, Volume: 38, Issue:1

    Topics: Animals; Castration; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Humans; Injections, Subcutaneous; Male; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Organ Size; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Seminal Vesicles; Sex Factors; Testosterone

1991
Assessment of the critical level of androgen for growth response of transplantable human prostatic carcinoma (PC-82) in nude mice.
    The Journal of urology, 1991, Volume: 145, Issue:3

    Topics: Animals; Dihydrotestosterone; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Testosterone

1991
[Hormone-dependency of the human prostate].
    Bulletin du cancer, 1986, Volume: 73, Issue:1

    Topics: Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid

1986
Dihydrotestosterone measured in core biopsies from prostatic tissues.
    American journal of clinical oncology, 1988, Volume: 11 Suppl 2

    Topics: Aged; Aged, 80 and over; Biopsy; Cell Nucleus; Dihydrotestosterone; DNA; DNA, Neoplasm; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms

1988
[A study on usefulness of the crude nuclear DHT measurement in prostatic cancer patients].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1989, Volume: 80, Issue:9

    Topics: Androgens; Cell Nucleus; Dihydrotestosterone; Humans; Male; Methods; Neoplasms, Hormone-Dependent; Predictive Value of Tests; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen

1989
Response to cyproterone acetate treatment in primary hepatocellular carcinoma is related to fall in free 5 alpha-dihydrotestosterone.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:11

    Topics: Adult; Aged; Androgen Antagonists; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasms, Hormone-Dependent

1987
Androgens, adrenal androgen precursors, and their metabolism in untreated primary tumors and lymph node metastases of human prostatic cancer.
    American journal of clinical oncology, 1988, Volume: 11 Suppl 2

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Androgens; Androstenediols; Androstenedione; Arylsulfatases; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Humans; Lymphatic Metastasis; Male; Neoplasms, Hormone-Dependent; Oxidoreductases; Prostate; Prostatic Neoplasms; Steryl-Sulfatase; Testosterone

1988
Hormonal agents and treatment of cancer.
    Urology, 1986, Volume: 27, Issue:1 Suppl

    Topics: Androgens; Breast Neoplasms; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Female; Flutamide; Hormones; Humans; Male; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen

1986
Comparison of the efficacy of subcutaneous and nasal spray buserelin treatment in suppression of testicular steroidogenesis in men with prostate cancer.
    Fertility and sterility, 1986, Volume: 46, Issue:1

    Topics: Administration, Intranasal; Aged; Buserelin; Dihydrotestosterone; Drug Evaluation; Estradiol; Gonadal Steroid Hormones; Humans; Injections, Subcutaneous; Luteinizing Hormone; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prospective Studies; Prostatic Neoplasms; Random Allocation; Testis; Testosterone

1986
alpha-Difluoromethylornithine enhancement of 14C-putrescine uptake by an androgen-dependent prostatic tumor.
    The Journal of urology, 1986, Volume: 136, Issue:4

    Topics: Adenocarcinoma; Androgens; Animals; Carbon Radioisotopes; Dexamethasone; Dihydrotestosterone; Eflornithine; Male; Neoplasms, Hormone-Dependent; Premedication; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats

1986
Androgen-dependent human prostate cancer in nude mice. The PC-82 tumor model.
    American journal of clinical oncology, 1988, Volume: 11 Suppl 2

    Topics: Adenocarcinoma; Animals; Dihydrotestosterone; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Testosterone

1988
Prostatic carcinogenesis evoked by cellular interaction.
    Environmental health perspectives, 1988, Volume: 77

    Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Epithelium; Fibroblasts; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Tumor Cells, Cultured

1988
The effect of 4MA, a potent inhibitor of 5 alpha-reductase, on the growth of androgen-responsive human genitourinary tumors grown in athymic nude mice.
    The Prostate, 1987, Volume: 10, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Androgens; Animals; Azasteroids; Dihydrotestosterone; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Steroids, Heterocyclic; Transplantation, Heterologous

1987
Androgen dependence of the Dunning R3327G cell line in monolayer culture.
    The Prostate, 1987, Volume: 11, Issue:4

    Topics: Androgen Antagonists; Androgens; Animals; Cell Division; Cell Line; Dihydrotestosterone; Flutamide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Rats; Tumor Cells, Cultured

1987
Growth-stimulating effect of pharmacological doses of estrogen on androgen-dependent Shionogi carcinoma 115 in vivo but not in cell culture.
    Cancer research, 1987, Jan-01, Volume: 47, Issue:1

    Topics: Androgens; Animals; Blood Physiological Phenomena; Carcinoma; Cell Division; Cells, Cultured; Culture Media; Dihydrotestosterone; Estradiol; Estrogens; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Testosterone

1987