Page last updated: 2024-08-21

dihydrotestosterone and Disease Models, Animal

dihydrotestosterone has been researched along with Disease Models, Animal in 198 studies

Research

Studies (198)

TimeframeStudies, this research(%)All Research%
pre-199017 (8.59)18.7374
1990's18 (9.09)18.2507
2000's42 (21.21)29.6817
2010's91 (45.96)24.3611
2020's30 (15.15)2.80

Authors

AuthorsStudies
Amano, K; Ishii, T; Ishizuka, Y; Nagao, M; Nishii, Y; Nishimura, K; Ootake, T; Sueishi, K; Watanabe, A1
Bachmann, M; Gonther, S; Mühl, H; Stülb, H1
Billig, H; Brännström, M; Hu, M; Li, J; Liang, M; Ma, H; Ma, S; Sferruzzi-Perri, AN; Shao, LR; Wang, X; Wu, X; Zhang, Y1
Goudarzi, M; Kalantar, H; Kalantar, M; Kalantari, H; Mansouri, E; Shabani, E1
Cochran, BJ; Edwards, MC; Gilchrist, RB; Handelsman, DJ; Hu, Y; Ledger, WL; Padmanabhan, V; Rodriguez Paris, V; Rye, KA; Walters, KA; Xiong, T1
Abe, S; Cui, G; Ejima, A; Hirai, T; Ikuta, K; Kato, S; Munakata, S; Sato, S; Shimba, A; Takeuchi, O; Tani-Ichi, S; Uehata, T1
Banks, DB; Binder, AK; Gutierrez, SD; Korach, KS; Magaña, J; Peecher, DL; Qvigstad, AJ1
Djordjevic, A; Ignjatović, Đ; Macut, D; Mićić, B; Tomić, M; Tovilović-Kovačević, G; Vojnović Milutinović, D1
Anderson, GM; Inglis, MA; Kerbus, RI1
Ahima, R; Awe, O; Feng, M; Ma, Y; Segars, J; Shen, M; Wang, Z; Wolfe, A; Wu, S; Xue, P1
Hsia, SM; Lin, PH; Wang, KL; Wang, PS1
Chen, CW; Hsieh, RH; Lin, YL; Tsai, HH; Yu, PL1
Fiocco, A; Isidoro, C; Lima, P; Mazier, HL; Nivet, AL; Reunov, AA; Salehi, R; Tsang, BK; Wang, Q1
An, HJ; Jin, BR1
Gopalakrishnan, V; Krishnan, A; Muthusami, S; Periyasamy, L; Ramachandran, I; Stanley, JA1
Bar-Joseph, H; Ben-Ami, I; Miller, I; Nemerovsky, L; Shalgi, R1
Aflatounian, A; Cox, MJ; Edwards, MC; Gilchrist, RB; Handelsman, DJ; Ledger, WL; Padmanabhan, V; Rodriguez Paris, V; Walters, KA1
Baixeras, E; de Fonseca, FR; Gutierrez-Adan, A; Gutierrez-Arroyo, JL; Laguna-Barraza, R; Navarro, JA; Pericuesta, E; Ramos-Ibeas, P; Sanjuan, C; Vera, K1
Chen, HT; Condor, B; Cooper, MS; Handelsman, DJ; Kim, S; Lesmana, B; Li, Z; Lo, TH; Ma, D; Maitz, PK; Parungao, RJ; Shi, H; Silveira, PA; Simanainen, U; Tsai, KH; Wang, Y1
Fu, P; Gao, Z; Ge, Y; Liu, J; Liu, Z; Ma, X; Wang, L; Yan, X; Yao, R1
Brkljačić, J; Djordjevic, A; Jelača, S; Macut, D; Teofilović, A; Veličković, N; Vojnović Milutinović, D1
An, HJ; Jin, BR; Kim, HJ1
Billig, H; Cui, P; Feng, Y; Hu, M; Hu, W; Li, X; Ma, T; Shao, LR; Shi, J; Tong, X; Xu, X; Zhang, F1
Chen, Y; Du, L; Fu, D; Guo, Y; He, Y; Hu, Z; Huang, J; Li, K; Miao, Y; Qu, Q; Sun, Y1
Aflatounian, A; Anderson, RA; Begg, DP; Bertoldo, MJ; Campbell, RE; Edwards, MC; Gilchrist, RB; Handelsman, DJ; Nagarkar, R; Padmanabhan, V; Rodriguez Paris, V; Sucquart, IE; Walters, KA1
Ahn, JH; Ahn, SH; Bae, MA; Cho, SH; Hwang, KS; Kan, H; Kim, SS; Lee, BH; Shin, DS; Son, Y; Yang, JY1
Davenport, K; Everman, SJ; Logan, MK; Pruett, JE; Romero, DG; Torres Fernandez, ED; Vinson, RM; Yanes Cardozo, LL; Ye, SA1
Busada, JT; Cidlowski, JA; Cook, DN; Khadka, S; Oakley, RH; Peterson, KN; Xu, X1
Cabrita, I; Kunzelmann, K; Schreiber, R; Talbi, K1
Benrick, A; Carlström, M; Cushman, SW; Fornes, R; Hu, M; Ivarsson, N; Maciel, GAR; Maliqueo, M; Marcondes, RR; Stener-Victorin, E; Stenkula, KG1
Adlanmerini, M; Arnal, JF; Boudou, F; Chantalat, E; Chenu, C; Gadeau, AP; Guihot, AL; Henrion, D; Lenfant, F; Raymond-Letron, I; Toutain, C; Vicendo, P1
Antić, IB; Bursać, B; Djordjevic, A; Macut, D; Macut, JB; Matić, G; Milutinović, DV; Nestorov, J; Nikolić, M; Teofilović, A; Veličković, N; Zidane, AS1
Cordaro, M; Cuzzocrea, S; Di Paola, R; Esposito, E; Fusco, R; Gugliandolo, E; Impellizzeri, D; Inferrera, A; Siracusa, R1
Chung, YM; Dai, C; Klein, EA; Kovac, E; Li, J; Magi-Galluzzi, C; Sharifi, N; Stephenson, AJ; Zhu, Z1
Jeon, WY; Jin, SE; Kim, JA; Kim, OS; Kim, YU; Lee, MY; Seo, CS; Shin, HK1
Benrick, A; Chanclón, B; Hadi, L; Micallef, P; Shelton, JM; Stener-Victorin, E; Wernstedt Asterholm, I; Wu, Y1
Lee, DR; Lim, JJ; Lima, PDA; Salehi, R; Tsang, BK1
Chen, ZJ; Fan, HY; Ji, SY; Li, BT; Liu, HB; Liu, J; Liu, XM; Zhang, YC; Zhang, YL1
Gao, J; Jia, L; Li, X; Liu, M; Ma, S; Sun, J; Tsang, SY; Wang, M; Xu, Y; Zhang, H1
Chen, Y; Chen, Z; Liu, X; Liu, Z; Wei, R; Xu, X; Xue, P; Yang, X1
Ishikawa, K; Kogame, A; Matsui, H; Tagawa, Y; Tanaka, A; Watanabe, T1
Campolo, M; Cordaro, M; Cuzzocrea, S; Esposito, E; Filippone, A; Paterniti, I; Siracusa, R1
Chen, YA; Cheung, A; Leader, A; Lima, PDA; Nivet, AL; Tsang, BK; Tzeng, CR; Wang, Q1
Büyükalpelli, R; Diri, B; Diri, MA; Yildiz, L1
Briden, KE; Hreha, TN; Hruska, KA; Hunstad, DA; Liu, A; McLellan, LK; Olson, PD1
Hu, Q; Jin, J; Liu, P; Qian, W; Sheng, L; Tang, C; Wang, X; Yu, D; Zhang, J; Zhong, Y; Zhou, H; Zhou, Y1
An, HJ; Jin, BR; Kim, HJ; Kim, MS; Lee, KH; Park, SK; Yoon, IJ1
Cui, P; Feng, Y; Hu, W; Li, X; Ma, T; Shao, LR; Tong, X; Zhang, F1
Moulana, M1
Bender, RA; Gölz, C; Hirnet, T; Kirchhoff, FP; Rune, GM; Schäfer, MKE; Schmidt, M; Westerhorstmann, J1
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Lee, JH; Roh, DH; Yoon, SY1
Li, MX; Sun, LF; Xiao, TX; Yang, YL; Zhang, JV1
Irahara, M; Iwasa, T; Kawakita, T; Matsuzaki, T; Mayila, Y; Yanagihara, R1
Andersson, D; Benrick, A; Carlström, M; Fornes, R; Manti, M; McCann Haworth, S; Pironti, G; Stener-Victorin, E; Zhengbing, Z1
Menaker, M; Murphy, ZC; Sellix, MT1
Cui, H; Du, J; Kang, L; Li, N; Li, S; Xie, G; Zhang, C; Zhang, Y1
Jang, HS; Jung, KJ; Kim, JI; Park, KM1
Danser, AH; de Vries, R; Garrelds, IM; Kramer, P; Labruijere, S; Musterd-Bagghoe, UM; Van Den Brink, AM; van Houten, EL; Villalón, CM; Visser, JA1
Benko, R; Benyó, Z; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Nadasy, GL; Novak, A; Revesz, C; Ruisanchez, E; Sara, L; Tarszabo, R; Tokes, AM; Varbiro, S1
Herson, PS; Klawitter, J; Macey, TA; Perraud, AL; Quillinan, N; Shimizu, T; Traystman, RJ1
Brown, R; Donner, NC; Handa, RJ; Kudwa, AE; McGivern, RF1
Kyoung, H; Lee, MY; Seo, CS; Shin, HK; Shin, IS; Son, JK1
Dong, Y; Guy, RK; Keiser, J; Lin, MF; Min, J; Muniyan, S; Vargas, M; Vennerstrom, JL; Wang, C; Wang, X; Zhao, Q1
Hwang, ES; Lee, DG; Mavlonov, GT; Park, SY; Shin, HS; Yi, TH1
Gray, AL; Greensmith, L; Hanna, MG; La Spada, AR; Malik, B; Montague, K; Szabadkai, G1
Antal, P; Benkő, R; Csibi, N; Monori-Kiss, A; Monos, E; Nádasy, GL; Novak, A; Paragi, P; Sára, L; Szekeres, M; Tarszabo, R; Tőkés, AM; Várbíró, S1
Matiller, V; Ortega, HH; Padmanabhan, V; Salvetti, NR1
Anselmo-Franci, JA; Brandão, ML; Del-Ben, CM; Graeff, FG; Leite, CM; Lima, FB; Pestana-Oliveira, N; Reis, FM1
Arteaga, CL; Balko, JM; Bauer, JA; Chen, X; Gómez, H; Johnson, KC; Lehmann, BD; Mills, GB; Pendleton, CS; Pietenpol, JA; Sanders, ME; Schafer, JM; Tang, L1
Azzarolo, AM; Czerwinski, S; Mostafa, S; Rowan, VS1
Chong, LM; Jia, YL; Li, L; Liu, X; Ma, AC; Sun, ZY; Yan, JY; Zhou, L1
Adjei, S; Afriyie, DK; Asare, GA; Bugyei, K; Hong, ZF; Lin, JM; Peng, J1
Amos-Landgraf, JM; Clipson, L; Dove, WF; Dunkin, E; Ederveen, AG; Groothuis, PG; Heijmans, J; Hommes, DW; Krentz, KJ; Mosselman, S; Muncan, V; Shedlovsky, A; van den Brink, GR; Wielenga, MC1
Kang, Q; Li, L; Wang, S; Zheng, X1
Chen, KC; Chyau, CC; Lin, YT; Peng, CC; Peng, RY1
Erbas, O; Ergenoglu, M; Karadadas, N; Taskiran, D; Yavasoglu, A; Yeniel, O; Yildirim, AG; Yildirim, N1
Bui, E; do Carmo, JM; Granger, JP; Hall, JE; Lima, R; Maranon, R; Moulana, M; Reckelhoff, JF; Smith, AD; Spradley, FT; Thomas, RL; Zhang, H1
Bernstein, KE; Capdevila, JH; Dakarapu, R; Ding, Y; Falck, JR; Garcia, V; Gotlinger, K; Joseph, G; Schwartzman, ML; Shkolnik, B; Zhang, FF1
Bjekić-Macut, J; Božić-Antić, I; Korićanac, G; Macut, D; Matić, G; Milutinović, DV; Nikolić, M; Rodaljević, S; Stanišić, J; Tepavčević, S1
Bi, J; Hoang, V; Mohankumar, SM; Vyas, AK1
Grayson, BE; Ressler, IB; Seeley, RJ; Ulrich-Lai, YM1
Cha, JY; Chang, BC; Choi, YL; Hong, GS; Jang, Y; Jung, J; Lee, B; Lee, HY; Lee, MO; Min, HY; Na, TY; Oh, U; Shin, YK; Wee, J1
Al Sweidi, S; Bourque, M; Caruso, D; Di Paolo, T; Melcangi, RC; Morissette, M1
Gao, A; Hou, P; Liu, L; Lv, H; Shi, B; Wu, L; Wu, Q; Xie, C; Xu, L; Zhang, Q1
Sasaki, M; Shimokado, K; Shinozaki, S1
Feng, J; Gao, H; Huang, B; Li, L; Li, X; Li, Y; Liu, D; Liu, J; Lu, J; Wang, G; Zhang, L; Zhang, N; Zhang, Y1
Andrisse, S; Billings, K; Chen, Y; Childress, S; Ma, Y; Sonko, ML; Stewart, A; Wolfe, A; Wu, S; Xue, P1
Goto, M; Iwase, A; Kikkawa, F; Kondo, M; Kotani, T; Nakahara, T; Nakamura, T; Osuka, S; Saito, A; Takikawa, S1
Barrios, C; Batruch, I; Clotet, S; Diamandis, EP; Dimitromanolakis, A; Fang, F; Konvalinka, A; Pascual, J; Riera, M; Scholey, JW; Soler, MJ; Vasiliou, SK; Zhou, J1
Ahn, HS; Jeon, GS; Kim, JH; Lee, BM; Lee, EJ; Park, SI; Park, SW; Won, JH1
Cajander, S; Lönn, M; Mannerås, L; Stener-Victorin, E1
Boonen, S; Bouillon, R; Callewaert, F; Ophoff, J; Vanderschueren, D; Venken, K1
Frye, CA; Walf, AA1
Cheng, J; DeVries, AC; Herson, PS; Hurn, PD; Palmateer, JM; Uchida, M1
Bernoulli, J; Santti, R; Talvitie, EM; Yatkin, E1
Benice, TS; Raber, J1
Abel, MH; De Gendt, K; Monteiro, A; O'Shaughnessy, PJ; Verhoeven, G1
Calza, L; Caruso, D; D'Intino, G; Garcia-Segura, LM; Giatti, S; Maschi, O; Melcangi, RC; Pesaresi, M1
Coughlin, L; Foecking, EM; Jones, KJ; Marzo, SJ; Porter, RG; Sharma, N; Tanzer, L; Wurster, RD1
Li, ZL; Lin, H; Liu, YM; Wang, SH; Wu, CY; Wu, XY; Xiao, WF1
Chippari, S; Crabtree, JS; Harris, HA; Kenney, T; Kilbourne, EJ; McNally, C; Nagpal, S; Peano, BJ; Thompson, CC; Wang, W; Winneker, RC1
Walker, WH1
Hong, JH; Kang, HS; Kim, JH; Park, HG; Ro, JY; Song, HY; Yoon, CJ1
Carroll, J; Pike, CJ; Rosario, ER1
Ely, D; Ramirez, R; Salisbury, R; Toot, J1
He, GL; Jiang, XR; Liu, GM; Liu, XY; Sun, ZY; Wu, JH1
Davis, DD; Lima, R; Lockhart, R; Moulana, M; Racusen, LC; Reckelhoff, JF; Romero, DG; Yanes, LL; Zhang, H1
Balk, S; Marck, BT; Matsumoto, AM; Montgomery, RB; Mostaghel, EA; Nelson, PS; Plymate, SR; Vessella, RL1
Seeley, RJ; Wilson-Pérez, HE1
Billig, H; Egecioglu, E; Feng, Y; Johansson, J; Shao, R; Stener-Victorin, E; Sun, S; Wang, T; Wang, W; Weijdegård, B1
Espallergues, J; Koseki, T; Laruelle, C; Mamiya, T; Maurice, T; Nabeshima, T; Temsamani, J; Vallée, M1
Kang, H; Kim, HO; Kim, HS; Kim, MH; Kim, YY; Park, YM; Up No, S1
Antal, P; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Monos, E; Nadasy, GL; Sara, L; Varbiro, S1
Spence, RD; Voskuhl, RR1
Azzarolo, AM; Mostafa, S; Seamon, V1
Ha, HK; Lee, MY; Lee, NH; Seo, CS; Shin, HK; Shin, IS; Son, JK1
Ha, HK; Jung, DY; Lee, MY; Seo, CS; Shin, HK; Shin, IS1
Couse, JF; Jefferson, WN; Korach, KS; Walker, VR1
Flynn, ER; Hutchens, ZM; Manigrasso, MB; Maric-Bilkan, C; Sawyer, RT1
Karels, B; Kramer, P; McLuskey, A; Themmen, AP; van Houten, EL; Visser, JA1
Billig, H; Feng, Y; Johansson, J; Mannerås-Holm, L; Shao, R; Stener-Victorin, E1
Gao, PJ; Lu, YL; Shen, ZJ; Wang, XJ; Wu, W; Zhang, CM; Zhang, MG1
Ha, HK; Lee, MY; Seo, CS; Shin, HK; Shin, IS1
Ko, CP; Yoo, YE1
Antal, P; Masszi, G; Monori-Kiss, A; Monos, E; Nadasy, GL; Sara, L; Szekeres, M; Varbiro, S1
Allan, CM; Foo, CF; McCabe, MJ; McTavish, KJ; Nicholls, PK; Stanton, PG1
Amorim, JP; Chuffa, LG; Fávaro, WJ; Fioruci, BA; Martinez, FE; Martinez, M; Martins, OA; Mendes, LO; Oba, E; Pinheiro, PF; Teixeira, GR1
Kim, JY; Leader, A; Liu, JY; Tsang, BK; Wang, Q; Xue, K1
Benko, R; Benyó, Z; Buday, A; Hamar, P; Horvath, EM; Masszi, G; Nadasy, GL; Novak, A; Revesz, C; Sara, L; Tarszabo, R; Varbiro, S1
Billig, H; Johansson, J; Lönn, M; Mannerås-Holm, L; Olsson, A; Shao, R; Stener-Victorin, E1
Klimova, OP1
Cotroneo, MS; Eltoum, IE; Fritz, WA; Lamartiniere, CA1
Boonen, S; Bouillon, R; Swinnen, JV; Van Herck, E; Vandenput, L; Vanderschueren, D1
Engelbach, JA; Jones, LA; Kim, J; Mercer, NM; Oyama, N; Sharp, TL; Welch, MJ1
He, GL; Liu, GM; Sun, ZY; Wu, JH; Zhong, EH; Zhu, Y1
Amano, S; Furuya, K; Hanada, K; Ichikawa, K; Miyakawa, M; Nakamura, T; Nejishima, H; Oguro, N; Sumita, Y; Yamamoto, N1
Buggage, RR; Chan, CC; Matteson, DM; Shen, DF; Sun, B; Tuaillon, N1
Constantinou, CE; Gotanda, K; Honda, K; Nomiya, M; Tsuruya, Y; Yamaguchi, O; Yokota, T1
Angele, MK; Angele, P; Chaudry, IH; Hatz, R; Hernandez-Richter, T; Jauch, KW; Nitsch, SM; Wichmann, MW; Wittmann, F1
Jesmin, S; Kitabatake, A; Mowa, CN; Sakuma, I; Togashi, H; Ueno, K; Yamaguchi, T; Yoshioka, M1
Banerjee, T; Pham, H; Ziboh, VA1
Reddy, A; Sinha, AA; Wiehr, C; Wilson, MJ; Woodson, M1
Davey, RA; Morris, HA1
DonCarlos, LL; Huppenbauer, CB; Jones, KJ; Tanzer, L1
Grantham, J; Kurahashi, H; Kusaka, M; Marunouchi, T; Nagao, S; Nishii, K; Takahashi, H1
Becker, RE; Dalrymple, SL; Denmeade, SR; Isaacs, JT; Xu, Y1
Fukuzumi, H; Ikeda, T; Matsuda, T; Narita, H; Takubo, T; Taniguchi, T1
Greenberg, NM; Roselli, CE; Wadsworth, TL; Worstell, TR1
Cajander, S; Holmäng, A; Lönn, M; Lystig, T; Mannerås, L; Seleskovic, Z; Stener-Victorin, E1
Cunningham, GR; Ittmann, M; Li, H; Shao, TC1
Abhirami, R; Ganesan, K; Manohar, BM; Puvanakrishnan, R; Raju, KV; Selvam, R1
Ganesan, AP; Gauthaman, K1
McCarthy, MM; Nuñez, JL1
Quigley, R1
Cassis, LA; Daugherty, A; Henriques, T; Yiannikouris, FB; Zhang, X1
Wilson, JD1
Bagnell, CA; Costoff, A; Mahesh, VB; Mills, TM1
Krueger, GG; Petersen, MJ; Zone, JJ1
Matsumoto, K; Tsuji, M1
Fukabori, Y; Hamataki, N; Honma, S; Ito, K; Kushitani, M; Mieda, M; Suzuki, K; Takezawa, Y; Yamanaka, H1
Berry, SJ; Coffey, DS; Ewing, LL; Juniewicz, PE; Strandberg, JD1
Bosland, MC; Falvo, RE; Liehr, JG; Nagamani, M; Wade, DR; Winter, ML1
Araneo, BA; Barton, S; Daynes, RA; Ryu, SY1
Ball, RA; Leder, P; Ornitz, DM; Richie, JP; Tutrone, RF1
Cutolo, M; Da Silva, JA; Larbre, JP; Scott, DL; Seed, MP; Villaggio, B; Willoughby, DA1
Bowman, BM; Coxam, V; Mecham, M; Miller, MA; Miller, SC; Roth, CM1
Formby, B; Takei, S; Toyoda, H1
Bélanger, A; Labrie, C; Labrie, F; Luo, S1
Imamura, K; Imanishi, N; Rhodes, L; Uno, H; Ye, F1
Constantinou, CE; Lee, JZ; Omata, S; Perkash, I; Tillig, B1
Angele, MK; Ayala, A; Bland, KI; Chaudry, IH; Cioffi, WG; Monfils, BA1
Nelson, JB; Pflug, BR; Reiter, RE1
Cochrane, DE; Feldberg, RS; Harris, MT; Lau, KM; Lazarus, NH1
Chang, SM; Chung, LW; Degeorges, A; Ozen, M; Pathak, S; Sikes, RA; Thalmann, GN; Wu, TT1
Matsumoto, T; Mori, M; Takagi, H1
Anidjar, M; Barnoux, M; Berthon, P; Billotey, C; Cochand-Priollet, B; Copin, H; Cotard, JP; Cussenot, O; Delisle, F; Devauchelle, P; Fiet, J; Rain, JD; Teillac, P; Triballeau, S; Villette, JM1
Adams, JY; Alroy, J; Leav, I; Merk, FB; Schelling, KH2
Anderson, E; Aziz, N; Lee, GY; Woo, D1
Bland, KI; Chaudry, IH; Rue, LW; Samy, TS; Schneider, CP; Zheng, R1
Walsh, PC; Wilson, JD1
Chu, TM; Gaeta, JF; Murphy, GP; Saroff, J; Williams, P1
Goodman, JR; Greenspan, JS; Roubinian, JR; Siiteri, PK; Talal, N1
Sandberg, AA1
Bogovich, K1
Bayley, DL; Steward, A1
Adachi, K; Cappas, A; Kamoda, H; Kemnitz, JW; Sakuma, A; Uno, H1
Bullock, BC; McLachlan, JA; Newbold, RR1
Greger, NG; Insull, W; Keenan, BS; Probstfield, JL1
Robinette, CL1
Luckert, PH; Pollard, M; Snyder, D1
Rao, BR1
Bell, C; Chang, SM; Chung, LW; Ro, JY; von Eschenbach, AC; Zhau, H1
Loriaux, DL; Mellin, TN; Povar, ML; Rittmaster, RS; Uno, H1
Gehring, U; Tomkins, GM1
Attardi, B; Ono, S1
Ono, S1
Bardin, CW; Blackburn, WR; Bullock, L; Sherins, RJ; Vanha-Perttula, T1

Reviews

5 review(s) available for dihydrotestosterone and Disease Models, Animal

ArticleYear
Neuroprotective effects of estrogens and androgens in CNS inflammation and neurodegeneration.
    Frontiers in neuroendocrinology, 2012, Volume: 33, Issue:1

    Topics: Animals; Central Nervous System Diseases; Dihydrotestosterone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Estradiol; Estriol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Inflammation; Male; Mice; Multiple Sclerosis; Neuroprotective Agents; Pregnancy; Selective Estrogen Receptor Modulators; Species Specificity; Testosterone

2012
Androgens stimulate proximal tubule transport.
    Gender medicine, 2008, Volume: 5 Suppl A

    Topics: Androgens; Angiotensin II; Animals; Blood Pressure; Dihydrotestosterone; Disease Models, Animal; Hypertension; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Up-Regulation

2008
The pathogenesis of benign prostatic hyperplasia.
    The American journal of medicine, 1980, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Androgens; Androstanols; Animals; Castration; Child; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrogens; Humans; Male; Middle Aged; Prostate; Prostatic Hyperplasia; Receptors, Androgen; Species Specificity; Testicular Hormones

1980
[Animal models with models receptor deficiencies--mice and rats as testicular feminization].
    Jikken dobutsu. Experimental animals, 1982, Volume: 31, Issue:4

    Topics: Androgen-Insensitivity Syndrome; Animals; Dihydrotestosterone; Disease Models, Animal; Female; Male; Mice; Pregnancy; Rats; Receptors, Androgen; Receptors, Steroid; Rodent Diseases; Testosterone

1982
Potential test systems for chemotherapeutic agents against prostatic cancer.
    Vitamins and hormones, 1975, Volume: 33

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Antineoplastic Agents; Arginase; Dihydrotestosterone; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Estradiol; Estramustine; Estriol; Estrogens; Flutamide; Haplorhini; Humans; Male; Mice; Neoplasms, Experimental; Prostate; Prostatic Neoplasms; Rats; Testosterone

1975

Trials

1 trial(s) available for dihydrotestosterone and Disease Models, Animal

ArticleYear
Effect of dehydroepiandrosterone on bone mass, serum lipids, and dimethylbenz(a)anthracene-induced mammary carcinoma in the rat.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Body Weight; Bone Density; Calcium; Carcinogens; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Femur; Lipids; Lumbar Vertebrae; Mammary Neoplasms, Experimental; Phosphorus; Rats; Rats, Sprague-Dawley; Testosterone; Triglycerides

1997

Other Studies

192 other study(ies) available for dihydrotestosterone and Disease Models, Animal

ArticleYear
Effects of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice.
    Osteoarthritis and cartilage, 2021, Volume: 29, Issue:11

    Topics: Angiopoietin-Like Protein 7; Animals; Calcinosis; Carbonic Anhydrase I; Chondrocytes; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Male; Mandibular Condyle; Mice, Inbred C57BL; Orchiectomy; Osteoarthritis; Osteoclasts; Ovariectomy; Stress, Mechanical; Temporomandibular Joint; Up-Regulation

2021
Acetaminophen-Induced Liver Injury Exposes Murine IL-22 as Sex-Related Gene Product.
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: Acetaminophen; Adaptive Immunity; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression; Immunity, Innate; Inflammation; Interleukin-22; Interleukins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; Sex Factors; Signal Transduction; Spleen; T-Lymphocytes; Testosterone

2021
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome.
    Molecular human reproduction, 2021, 11-27, Volume: 27, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Dihydrotestosterone; Disease Models, Animal; Female; Ferroptosis; Glutathione; Insulin Resistance; Iron; Male; Malondialdehyde; Mitochondria; Oxidative Phosphorylation; Phospholipid Hydroperoxide Glutathione Peroxidase; Placenta; Polycystic Ovary Syndrome; Pregnancy; Rats, Sprague-Dawley; Signal Transduction; Uterus

2021
Berberine ameliorates testosterone-induced benign prostate hyperplasia in rats.
    BMC complementary medicine and therapies, 2021, Dec-20, Volume: 21, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Berberine; Dihydrotestosterone; Disease Models, Animal; Drugs, Chinese Herbal; Finasteride; Interleukin-1beta; Male; Oxidative Stress; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Testosterone; Tumor Necrosis Factor-alpha

2021
Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model.
    American journal of physiology. Endocrinology and metabolism, 2022, 08-01, Volume: 323, Issue:2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Female; Hyperandrogenism; Mice; Muscle, Skeletal; Phenotype; Polycystic Ovary Syndrome; Receptors, Androgen

2022
Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells.
    Journal of immunology (Baltimore, Md. : 1950), 2022, 09-15, Volume: 209, Issue:6

    Topics: 5' Untranslated Regions; Androgens; Animals; Asthma; Dihydrotestosterone; Disease Models, Animal; Dual-Specificity Phosphatases; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Hypersensitivity; Inflammation; Interleukin-4; Male; Mice; Mice, Knockout; Receptors, Androgen; Receptors, Estrogen; Th17 Cells; Th2 Cells

2022
Differential Strain-dependent Ovarian and Metabolic Responses in a Mouse Model of PCOS.
    Endocrinology, 2023, 02-11, Volume: 164, Issue:4

    Topics: Animals; Body Weight; Diabetes Mellitus, Type 1; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred NOD; Polycystic Ovary Syndrome

2023
Effects of early life overnutrition and hyperandrogenism on spatial learning and memory in a rat model of polycystic ovary syndrome.
    Hormones and behavior, 2023, Volume: 153

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Hyperandrogenism; Insulin; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Rats; Spatial Learning

2023
Neuronal Ptpn1 and Socs3 deletion improves metabolism but not anovulation in a mouse polycystic ovary syndrome model.
    The Journal of endocrinology, 2023, 09-01, Volume: 259, Issue:1

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin; Mice; Mice, Knockout; Neurons; Obesity; Polycystic Ovary Syndrome; Protein Tyrosine Phosphatase, Non-Receptor Type 1

2023
Gonadotrope androgen receptor mediates pituitary responsiveness to hormones and androgen-induced subfertility.
    JCI insight, 2019, 08-08, Volume: 5

    Topics: Animals; Calcium Signaling; Cells, Cultured; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Estrous Cycle; Female; Gonadotrophs; Gonadotropin-Releasing Hormone; Humans; Hyperandrogenism; Hypothalamo-Hypophyseal System; Infertility; Luteinizing Hormone; Mice; Mice, Transgenic; Monomeric GTP-Binding Proteins; Ovary; Primary Cell Culture; Receptors, Androgen; Up-Regulation

2019
Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:10

    Topics: Acetylcholine; Animals; Calcium Signaling; Carbachol; Colon; Dihydrotestosterone; Disease Models, Animal; Female; Gastrointestinal Diseases; Gastrointestinal Motility; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Phosphorylation; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Stomach

2020
Mangosteen pericarp components alleviate progression of prostatic hyperplasia and mitochondrial dysfunction in rats.
    Scientific reports, 2020, 01-15, Volume: 10, Issue:1

    Topics: Animals; Body Weight; Diet, High-Fat; Dietary Supplements; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Garcinia mangostana; Male; Malondialdehyde; Mitochondria; Nitric Oxide Synthase Type II; Oxidative Stress; Plant Extracts; Proliferating Cell Nuclear Antigen; Prostate; Prostatic Hyperplasia; Rats; Rats, Inbred F344; Testosterone

2020
Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome.
    Scientific reports, 2020, 01-23, Volume: 10, Issue:1

    Topics: Androgens; Animals; Apoptosis; Autophagy; Dihydrotestosterone; Disease Models, Animal; Dynamins; Female; Gonadotropins; Granulosa Cells; Mitochondria; Mitochondrial Dynamics; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley

2020
Baicalin alleviates benign prostate hyperplasia through androgen-dependent apoptosis.
    Aging, 2020, 02-04, Volume: 12, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Apoptosis; Cell Line; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Enzyme Inhibitors; Flavonoids; Humans; Male; Proliferating Cell Nuclear Antigen; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Androgen; Testosterone

2020
Effect of DHT-Induced Hyperandrogenism on the Pro-Inflammatory Cytokines in a Rat Model of Polycystic Ovary Morphology.
    Medicina (Kaunas, Lithuania), 2020, Feb-27, Volume: 56, Issue:3

    Topics: Animals; Cytokines; Dihydrotestosterone; Disease Models, Animal; Female; Follicle Stimulating Hormone; Hyperandrogenism; Inflammation Mediators; Insulin; Liver; Luteinizing Hormone; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Urocortins

2020
Pigment epithelium-derived factor (PEDF) negates hyperandrogenic PCOS features.
    The Journal of endocrinology, 2020, Volume: 245, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Dihydrotestosterone; Disease Models, Animal; Eye Proteins; Female; Granulosa Cells; Humans; Hyperandrogenism; Mice; Nerve Growth Factors; Ovary; Polycystic Ovary Syndrome; Serpins; Signal Transduction

2020
Androgen Action in Adipose Tissue and the Brain are Key Mediators in the Development of PCOS Traits in a Mouse Model.
    Endocrinology, 2020, 07-01, Volume: 161, Issue:7

    Topics: Adipose Tissue; Animals; Brain; Dihydrotestosterone; Disease Models, Animal; Female; Male; Mice, Knockout; Polycystic Ovary Syndrome; Receptors, Androgen

2020
D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome.
    International journal of molecular sciences, 2020, Aug-22, Volume: 21, Issue:17

    Topics: Aging; Animals; Blastocyst; Cumulus Cells; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression Regulation; Glucose Intolerance; Infertility, Female; Inositol; Liver; Male; Mice, Inbred Strains; Oocytes; Phosphorylation; Polycystic Ovary Syndrome; Proto-Oncogene Proteins c-akt; Testosterone Propionate

2020
Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice.
    International journal of molecular sciences, 2020, Aug-28, Volume: 21, Issue:17

    Topics: Androgens; Animals; Body Weight; Burns; Cell Proliferation; Collagen; Cytokines; Dihydrotestosterone; Disease Models, Animal; Male; Mice; Spleen; Wound Healing

2020
Troxerutin protects against DHT-induced polycystic ovary syndrome in rats.
    Journal of ovarian research, 2020, Sep-13, Volume: 13, Issue:1

    Topics: Animals; Body Weight; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gene Expression Regulation; Gene Regulatory Networks; Gonadotropin-Releasing Hormone; Gonadotropins; Hydroxyethylrutoside; Polycystic Ovary Syndrome; Rats; Testosterone

2020
Glucocorticoid signaling and lipid metabolism disturbances in the liver of rats treated with 5α-dihydrotestosterone in an animal model of polycystic ovary syndrome.
    Endocrine, 2021, Volume: 72, Issue:2

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Glucocorticoids; Humans; Lipid Metabolism; Liver; Polycystic Ovary Syndrome; Rats; Rats, Wistar

2021
Psoralea corylifolia L. extract ameliorates benign prostatic hyperplasia by regulating prostate cell proliferation and apoptosis.
    Journal of ethnopharmacology, 2021, Jun-12, Volume: 273

    Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Proliferating Cell Nuclear Antigen; Prostate-Specific Antigen; Prostatic Hyperplasia; Psoralea; Rats, Wistar; Receptors, Androgen; Testosterone Propionate

2021
Long-term androgen excess induces insulin resistance and non-alcoholic fatty liver disease in PCOS-like rats.
    The Journal of steroid biochemistry and molecular biology, 2021, Volume: 208

    Topics: Androgens; Animals; Apoptosis; Autophagy-Related Protein 12; bcl-2 Homologous Antagonist-Killer Protein; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin Resistance; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Obesity; Polycystic Ovary Syndrome; Reactive Oxygen Species; Risk Factors

2021
Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: Alopecia; Androgen Antagonists; Anilides; Animals; Dihydrotestosterone; Disease Models, Animal; Hair Follicle; Male; Mice; Mice, Inbred C57BL; Nitriles; Organ Culture Techniques; Receptors, Androgen; Signal Transduction; Tosyl Compounds

2021
Neurokinin 3 Receptor Antagonism Ameliorates Key Metabolic Features in a Hyperandrogenic PCOS Mouse Model.
    Endocrinology, 2021, 05-01, Volume: 162, Issue:5

    Topics: Androgens; Animals; Blood Glucose; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Hyperandrogenism; Lectins; Membrane Proteins; Mice; Mice, Inbred C57BL; Polycystic Ovary Syndrome; Receptors, Neurokinin-3; Triglycerides

2021
Neurochemical Effects of 4-(2Chloro-4-Fluorobenzyl)-3-(2-Thienyl)-1,2,4-Oxadiazol-5(4H)-One in the Pentylenetetrazole (PTZ)-Induced Epileptic Seizure Zebrafish Model.
    International journal of molecular sciences, 2021, Jan-28, Volume: 22, Issue:3

    Topics: Animals; Anticonvulsants; Antioxidants; Brain; Brain Chemistry; Dihydrotestosterone; Disease Models, Animal; Estradiol; gamma-Aminobutyric Acid; Hydrocortisone; Male; Neuroprotective Agents; Normetanephrine; Oxadiazoles; Oxidative Stress; Pentylenetetrazole; Pregnanolone; Progesterone; Reactive Oxygen Species; Seizures; Serotonin; Zebrafish

2021
Impact of SGLT-2 Inhibition on Cardiometabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome.
    International journal of molecular sciences, 2021, Mar-04, Volume: 22, Issue:5

    Topics: Animals; Benzhydryl Compounds; Dihydrotestosterone; Disease Models, Animal; Female; Glucosides; Heart; Hyperandrogenism; Polycystic Ovary Syndrome; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2021
Glucocorticoids and Androgens Protect From Gastric Metaplasia by Suppressing Group 2 Innate Lymphoid Cell Activation.
    Gastroenterology, 2021, Volume: 161, Issue:2

    Topics: Adrenalectomy; Androgens; Animals; Anti-Inflammatory Agents; Cellular Microenvironment; Dihydrotestosterone; Disease Models, Animal; Disease Susceptibility; Female; Gastric Mucosa; Gastritis, Atrophic; Glucocorticoids; Gonadal Steroid Hormones; Granulocyte-Macrophage Colony-Stimulating Factor; Homeodomain Proteins; Intercellular Signaling Peptides and Proteins; Interleukin-13; Interleukin-33; Lymphocytes; Male; Metaplasia; Mice, Inbred C57BL; Orchiectomy; Receptors, Androgen; Receptors, Glucocorticoid; Sex Factors; Signal Transduction; Thy-1 Antigens

2021
Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca
    International journal of molecular sciences, 2021, Jun-02, Volume: 22, Issue:11

    Topics: Animals; Anoctamin-1; Calcium; Calcium Signaling; Cell Proliferation; Chlorides; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Kidney; Male; Mice; Mice, Knockout; Phenotype; Polycystic Kidney Diseases; Sex Characteristics; TRPP Cation Channels

2021
Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome.
    Molecular and cellular endocrinology, 2017, 06-15, Volume: 448

    Topics: Adipocytes; Adipogenesis; Adipose Tissue, White; Animals; Body Composition; Body Weight; Cell Size; Dihydrotestosterone; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Glucose Tolerance Test; Insulin Resistance; Letrozole; Lipid Metabolism; Liver; Mice, Inbred C57BL; Nitriles; Organ Size; Phenotype; Physical Conditioning, Animal; Polycystic Ovary Syndrome; Signal Transduction; Triazoles; Triglycerides

2017
Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:5

    Topics: Animals; Cytokines; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Hormone Replacement Therapy; Ischemia; Male; Mesenteric Arteries; Mice, Hairless; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neovascularization, Physiologic; Orchiectomy; Rats, Wistar; Skin; Surgical Flaps; Time Factors; Tissue Survival; Wound Healing

2017
Enhanced Inflammation without Impairment of Insulin Signaling in the Visceral Adipose Tissue of 5α-Dihydrotestosterone-Induced Animal Model of Polycystic Ovary Syndrome.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2017, Volume: 125, Issue:8

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Inflammation; Insulin; Interleukin-1beta; Interleukin-6; Intra-Abdominal Fat; Obesity, Abdominal; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Signal Transduction

2017
Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia.
    Toxicology and applied pharmacology, 2017, 08-15, Volume: 329

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amides; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Drug Combinations; Drug Compounding; Ethanolamines; Glucosides; Inflammation Mediators; Male; Oxidative Stress; Palmitic Acids; Prostate; Prostatic Hyperplasia; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Testosterone Propionate

2017
Direct Metabolic Interrogation of Dihydrotestosterone Biosynthesis from Adrenal Precursors in Primary Prostatectomy Tissues.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Oct-15, Volume: 23, Issue:20

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Aged; Animals; Cell Line, Tumor; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Heterografts; Humans; Male; Metabolic Networks and Pathways; Mice; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prostate; Prostatectomy; Prostatic Neoplasms; Steroids; Substrate Specificity; Tandem Mass Spectrometry; Testosterone

2017
Inhibitory effects of Ponciri Fructus on testosterone-induced benign prostatic hyperplasia in rats.
    BMC complementary and alternative medicine, 2017, Aug-03, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Catalase; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Disease Models, Animal; Fruit; Glutathione Peroxidase; Glutathione Reductase; Male; Organ Size; Phytotherapy; Plant Extracts; Poncirus; Proliferating Cell Nuclear Antigen; Prostate; Prostatic Hyperplasia; Rats, Sprague-Dawley; Superoxide Dismutase; Testosterone; Testosterone Propionate

2017
Adiponectin protects against development of metabolic disturbances in a PCOS mouse model.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 08-22, Volume: 114, Issue:34

    Topics: Adiponectin; Adipose Tissue; Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin Resistance; Mice; Mice, Knockout; Polycystic Ovary Syndrome

2017
Regulation of androgen receptor signaling by ubiquitination during folliculogenesis and its possible dysregulation in polycystic ovarian syndrome.
    Scientific reports, 2017, 08-31, Volume: 7, Issue:1

    Topics: Animals; Biomarkers; Dihydrotestosterone; Disease Models, Animal; Female; Gonadotropins; Humans; Ovarian Follicle; Polycystic Ovary Syndrome; Rats; Receptors, Androgen; Signal Transduction; Stem Cell Factor; Ubiquitination

2017
The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse.
    Molecular human reproduction, 2017, 10-01, Volume: 23, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Proliferation; Chorionic Gonadotropin; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression Regulation; Gonadotropins, Equine; Granulosa Cells; Horses; Humans; Hyperandrogenism; Luteinizing Hormone; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovary; Ovulation; Phosphoproteins; Polycystic Ovary Syndrome; Primary Cell Culture; Signal Transduction; YAP-Signaling Proteins

2017
MicroRNA-27a-3p affects estradiol and androgen imbalance by targeting Creb1 in the granulosa cells in mouse polycytic ovary syndrome model.
    Reproductive biology, 2017, Volume: 17, Issue:4

    Topics: Androgens; Animals; Apoptosis; Aromatase; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Granulosa Cells; Mice; MicroRNAs; Polycystic Ovary Syndrome; Testosterone

2017
Dihydrotestosterone Treatment Accelerates Autograft Reversal Sciatic Nerve Regeneration in Rats.
    Neurochemical research, 2018, Volume: 43, Issue:3

    Topics: Animals; Autografts; Dihydrotestosterone; Disease Models, Animal; Male; Myelin P0 Protein; Nerve Regeneration; Peripheral Nerve Injuries; Rats, Sprague-Dawley; Sciatic Nerve

2018
Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model.
    European journal of pharmacology, 2018, Jun-05, Volume: 828

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Kisspeptins; Male; Prostatic Neoplasms; Rats; Xenograft Model Antitumor Assays

2018
Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH).
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2018, Volume: 67, Issue:7

    Topics: Ajuga; Animals; Apoptosis; Cholestenone 5 alpha-Reductase; Cyclooxygenase 2; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Epilobium; Male; Malondialdehyde; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Prostate; Prostatic Hyperplasia; Rats, Sprague-Dawley; Selenium; Serenoa; Testosterone Propionate

2018
Polycystic ovary syndrome: possible involvement of androgen-induced, chemerin-mediated ovarian recruitment of monocytes/macrophages.
    Biology of reproduction, 2018, 10-01, Volume: 99, Issue:4

    Topics: Androgens; Animals; Apoptosis; Cell Movement; Chemokines; Dihydrotestosterone; Disease Models, Animal; Female; Granulosa Cells; Humans; Hyperandrogenism; Intercellular Signaling Peptides and Proteins; Macrophages; Monocytes; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Receptors, Chemokine

2018
The effect of dutasteride on microscopic and macroscopic changes of testosterone replacement treatment on prostate tissue.
    Andrologia, 2018, Volume: 50, Issue:10

    Topics: 5-alpha Reductase Inhibitors; Animals; Dihydrotestosterone; Disease Models, Animal; Dutasteride; Hormone Replacement Therapy; Humans; Male; Orchiectomy; Precancerous Conditions; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone; Treatment Outcome

2018
Androgen exposure potentiates formation of intratubular communities and renal abscesses by Escherichia coli.
    Kidney international, 2018, Volume: 94, Issue:3

    Topics: Abscess; Androgen Receptor Antagonists; Androgens; Animals; Benzamides; Dihydrotestosterone; Disease Models, Animal; Disease Susceptibility; Escherichia coli Infections; Female; Humans; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitriles; Phenylthiohydantoin; Pyelonephritis; Receptors, Androgen; Sex Factors; Toll-Like Receptor 4; Treatment Outcome; Urinary Tract Infections; Uropathogenic Escherichia coli

2018
Crocetin attenuates DHT-induced polycystic ovary syndrome in mice via revising kisspeptin neurons.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Carotenoids; Crocus; Dihydrotestosterone; Disease Models, Animal; Drugs, Chinese Herbal; Estrous Cycle; Female; Hypothalamo-Hypophyseal System; Hypothalamus, Anterior; Kisspeptins; Neurons; Ovary; Polycystic Ovary Syndrome; Vitamin A

2018
Anti-Proliferative Effects of HBX-5 on Progression of Benign Prostatic Hyperplasia.
    Molecules (Basel, Switzerland), 2018, Oct-14, Volume: 23, Issue:10

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Cell Line; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Humans; Injections, Intramuscular; Male; Plant Extracts; Plants, Medicinal; Proliferating Cell Nuclear Antigen; Prostatic Hyperplasia; Rats; Receptors, Androgen; Testosterone Propionate

2018
Endogenous Ovarian Angiogenesis in Polycystic Ovary Syndrome-Like Rats Induced by Low-Frequency Electro-Acupuncture: The CLARITY Three-Dimensional Approach.
    International journal of molecular sciences, 2018, Nov-07, Volume: 19, Issue:11

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Electroacupuncture; Female; Imaging, Three-Dimensional; Neovascularization, Physiologic; Ovarian Follicle; Ovary; Polycystic Ovary Syndrome; Rats, Wistar

2018
Immunophenotypic profile of leukocytes in hyperandrogenemic female rat an animal model of polycystic ovary syndrome.
    Life sciences, 2019, Mar-01, Volume: 220

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Hyperandrogenism; Immunophenotyping; Leukocytes; Phenotype; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; T-Lymphocytes, Regulatory; Th17 Cells

2019
Sex hormones modulate pathogenic processes in experimental traumatic brain injury.
    Journal of neurochemistry, 2019, Volume: 150, Issue:2

    Topics: Animals; Brain; Brain Injuries, Traumatic; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Female; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Sex Characteristics

2019
Spinal cytochrome P450c17 plays a key role in the development of neuropathic mechanical allodynia: Involvement of astrocyte sigma-1 receptors.
    Neuropharmacology, 2019, 05-01, Volume: 149

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Astrocytes; Dihydrotestosterone; Disease Models, Animal; Hyperalgesia; Ketoconazole; Male; Mice; Mice, Inbred ICR; Neuralgia; Neurosteroids; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Receptors, sigma; Sciatic Nerve; Sigma-1 Receptor; Spinal Cord; Spinal Cord Dorsal Horn; Steroid 17-alpha-Hydroxylase

2019
Removal of DHT can relieve polycystic ovarian but not metabolic abnormalities in DHT-induced hyperandrogenism in mice.
    Reproduction, fertility, and development, 2019, Volume: 31, Issue:10

    Topics: Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Female; Gene Expression; Hyperandrogenism; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Ovary; Polycystic Ovary Syndrome; Stimulation, Chemical; Time Factors

2019
The effects of chronic oxytocin administration on body weight and food intake in DHT-induced PCOS model rats.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:1

    Topics: Adipocytes; Alanine Transaminase; Androgens; Animals; Aspartate Aminotransferases; Body Weight; Cell Size; Dihydrotestosterone; Disease Models, Animal; Eating; Female; Intra-Abdominal Fat; L-Lactate Dehydrogenase; Ovarian Cysts; Ovary; Oxytocics; Oxytocin; Polycystic Ovary Syndrome; Rats

2020
Maternal androgen excess induces cardiac hypertrophy and left ventricular dysfunction in female mice offspring.
    Cardiovascular research, 2020, 03-01, Volume: 116, Issue:3

    Topics: Animals; Diet, High-Fat; Dietary Sucrose; Dihydrotestosterone; Disease Models, Animal; Energy Metabolism; Female; Gene Expression Regulation; Hypertrophy, Left Ventricular; Maternal Exposure; Mesenteric Arteries; Mice, Inbred C57BL; Myocardium; NADPH Oxidases; Obesity; Polycystic Ovary Syndrome; Pregnancy; Sex Factors; Sexual Development; Sodium-Calcium Exchanger; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2020
Excess androgen during puberty disrupts circadian organization in female rats.
    Endocrinology, 2013, Volume: 154, Issue:4

    Topics: Adipose Tissue; Androgens; Animals; Body Weight; Circadian Clocks; Cornea; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Liver; Motor Activity; Ovarian Follicle; Period Circadian Proteins; Polycystic Ovary Syndrome; Rats; Rats, Transgenic; Sexual Maturation

2013
Effects of dihydrotestosterone on synaptic plasticity of hippocampus in male SAMP8 mice.
    Experimental gerontology, 2013, Volume: 48, Issue:8

    Topics: Alzheimer Disease; Androgens; Animals; Chromosome Pairing; Dihydrotestosterone; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Neuronal Plasticity; Orchiectomy; Receptors, N-Methyl-D-Aspartate; Synaptophysin

2013
Gender-specific role of HDAC11 in kidney ischemia- and reperfusion-induced PAI-1 expression and injury.
    American journal of physiology. Renal physiology, 2013, Jul-01, Volume: 305, Issue:1

    Topics: Acetylation; Animals; Binding Sites; Cell Line; Chromatin Immunoprecipitation; Dihydrotestosterone; Disease Models, Animal; Female; Histone Deacetylases; Histones; Kidney; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Ovariectomy; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Reperfusion Injury; RNA Interference; Serine Proteinase Inhibitors; Sex Factors; Time Factors; Transfection

2013
Analysis of the vascular responses in a murine model of polycystic ovary syndrome.
    The Journal of endocrinology, 2013, Volume: 218, Issue:2

    Topics: Acetylcholine; Animals; Aorta; Dihydrotestosterone; Disease Models, Animal; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Polycystic Ovary Syndrome; Vasodilation

2013
Effects of vitamin D3 derivative--calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcitriol; Dihydrotestosterone; Disease Models, Animal; Female; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasoconstriction; Vasodilation

2013
Androgen and PARP-1 regulation of TRPM2 channels after ischemic injury.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:10

    Topics: Androgens; Animals; Brain Ischemia; Cell Death; Cells, Cultured; Dihydrotestosterone; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Orchiectomy; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Primary Cell Culture; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Sex Characteristics; Signal Transduction; TRPM Cation Channels

2013
Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats.
    Brain research, 2013, Sep-05, Volume: 1529

    Topics: 5-alpha Reductase Inhibitors; Adrenocorticotropic Hormone; Animals; Corticosterone; Dihydrotestosterone; Disease Models, Animal; Estradiol; Finasteride; Hypothalamo-Hypophyseal System; Injections, Intra-Articular; Male; Orchiectomy; Pituitary-Adrenal System; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Physiological; Testosterone; Time Factors

2013
α-Spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model.
    Molecular medicine reports, 2014, Volume: 9, Issue:6

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Male; Organ Size; Plant Extracts; Prostate; Prostatic Hyperplasia; Rats; Stigmasterol; Testosterone

2014
Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978.
    The American journal of tropical medicine and hygiene, 2014, Volume: 90, Issue:6

    Topics: Androgen Receptor Antagonists; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Humans; Hydantoins; Imidazolidines; Male; Mice; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides

2014
Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:5

    Topics: Alopecia; Animals; Apoptosis; Caspase 12; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Finasteride; Ginsenosides; Hair Follicle; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Signal Transduction; Sterol Regulatory Element Binding Proteins; Transforming Growth Factor beta

2014
Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 7

    Topics: Age Factors; Androgens; Animals; Anterior Horn Cells; Apoptosis; Cells, Cultured; Dihydrotestosterone; Disease Models, Animal; Embryo, Mammalian; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Female; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscular Disorders, Atrophic; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spinal Cord; Thapsigargin

2014
Lower-limb veins are thicker and vascular reactivity is decreased in a rat PCOS model: concomitant vitamin D3 treatment partially prevents these changes.
    American journal of physiology. Heart and circulatory physiology, 2014, Sep-15, Volume: 307, Issue:6

    Topics: Animals; Cholecalciferol; Cyclooxygenase 2; Dihydrotestosterone; Disease Models, Animal; Female; Lower Extremity; Nitric Oxide Synthase Type III; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Saphenous Vein; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Venous Pressure

2014
Developmental programming: prenatal steroid excess disrupts key members of intraovarian steroidogenic pathway in sheep.
    Endocrinology, 2014, Volume: 155, Issue:9

    Topics: 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Aromatase; Biosynthetic Pathways; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrogens; Female; Humans; Male; Maternal Exposure; Ovarian Follicle; Phosphoproteins; Pregnancy; Prenatal Exposure Delayed Effects; Sheep; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone

2014
Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats.
    Psychoneuroendocrinology, 2014, Volume: 49

    Topics: Animals; Anxiety; Corticosterone; Cyclohexenes; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrous Cycle; Female; Follicle Stimulating Hormone; Maze Learning; Ovarian Follicle; Perimenopause; Primary Ovarian Insufficiency; Progesterone; Rats; Testosterone; Vinyl Compounds

2014
PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors.
    Breast cancer research : BCR, 2014, Aug-08, Volume: 16, Issue:4

    Topics: Androgen Receptor Antagonists; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Cluster Analysis; Dihydrotestosterone; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Receptors, Androgen; Signal Transduction; TOR Serine-Threonine Kinases; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2014
Time course of cytokine upregulation in the lacrimal gland and presence of autoantibodies in a predisposed mouse model of Sjögren's Syndrome: the influence of sex hormones and genetic background.
    Experimental eye research, 2014, Volume: 128

    Topics: Animals; Antibodies, Antinuclear; Autoantibodies; Cytokines; Dihydrotestosterone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Lacrimal Apparatus; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Oligonucleotide Array Sequence Analysis; Ovariectomy; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sjogren's Syndrome; Time Factors; Up-Regulation

2014
The alteration of inflammatory markers and apoptosis on chronic prostatitis induced by estrogen and androgen.
    International urology and nephrology, 2015, Volume: 47, Issue:1

    Topics: Animals; Apoptosis; Body Weight; Castration; Chemokine CCL3; Chronic Disease; Cyclooxygenase 2; Dihydrotestosterone; Disease Models, Animal; Estrogens; Male; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Testosterone; Tumor Necrosis Factor-alpha

2015
Treatment of benign prostatic hyperplasia with Croton membranaceus in an experimental animal model.
    Journal of ethnopharmacology, 2014, Nov-18, Volume: 157

    Topics: Animals; Croton; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Finasteride; Male; Medicine, Traditional; Plant Extracts; Plant Roots; Prostate-Specific Antigen; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley

2014
Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Nov-18, Volume: 111, Issue:46

    Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Animals, Congenic; Azoxymethane; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Genes, APC; Gonadal Steroid Hormones; Hormone Replacement Therapy; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mutation; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Specificity; Ovariectomy; Postmenopause; Random Allocation; Rats; Rats, Inbred F344; Rats, Mutant Strains; Receptors, Androgen; RNA, Messenger; Sex Distribution; Species Specificity

2014
Effects of androgen on ultrastructure of corneal epithelium and function of the tear film in BALB/c mice.
    Cornea, 2015, Volume: 34, Issue:3

    Topics: Androgens; Animals; Cornea; Dihydrotestosterone; Disease Models, Animal; Dry Eye Syndromes; Epithelium, Corneal; Fluorescein; Male; Mice; Mice, Inbred BALB C; Microvilli; Orchiectomy; Random Allocation; Tears

2015
Antrodan, a β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia.
    Food & function, 2015, Volume: 6, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antrodia; Aromatase; beta-Glucans; Cadherins; Cholesterol, HDL; Cholesterol, LDL; Cyclooxygenase 2; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Epithelial-Mesenchymal Transition; Estradiol; Humans; Interleukin-1; Male; Middle Aged; Plant Extracts; Prostate; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Androgen; Testosterone; Up-Regulation; Vimentin

2015
Effects of Resveratrol on Ovarian Morphology, Plasma Anti-Mullerian Hormone, IGF-1 Levels, and Oxidative Stress Parameters in a Rat Model of Polycystic Ovary Syndrome.
    Reproductive sciences (Thousand Oaks, Calif.), 2015, Volume: 22, Issue:8

    Topics: Animals; Anti-Mullerian Hormone; Antioxidants; Biomarkers; Dihydrotestosterone; Disease Models, Animal; Female; Glutathione Peroxidase; Insulin-Like Growth Factor I; Ovarian Follicle; Ovary; Oxidative Stress; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase

2015
Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Adrenergic Antagonists; Animals; Arterial Pressure; Dihydrotestosterone; Disease Models, Animal; Female; Hormone Antagonists; Hyperandrogenism; Hypertension; Hypothalamus; Kidney; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Signal Transduction; Sympathectomy; Sympathetic Nervous System; Time Factors

2015
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Transgenic; Microvessels; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors; Vascular Remodeling

2015
Cardiac Nitric Oxide Synthases and Na⁺/K⁺-ATPase in the Rat Model of Polycystic Ovary Syndrome Induced by Dihydrotestosterone.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2015, Volume: 123, Issue:5

    Topics: Animals; Cell Membrane; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Female; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Polycystic Ovary Syndrome; Protein Processing, Post-Translational; Protein Transport; Random Allocation; Rats, Wistar; Serine; Sodium-Potassium-Exchanging ATPase; Threonine; Up-Regulation

2015
Liraglutide improves hypertension and metabolic perturbation in a rat model of polycystic ovarian syndrome.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Abdominal Fat; Animals; Blood Pressure; Cholesterol; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Glucose; Hypertension; Liraglutide; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Telemetry; Weight Gain

2015
Diet-induced obesity exacerbates metabolic and behavioral effects of polycystic ovary syndrome in a rodent model.
    American journal of physiology. Endocrinology and metabolism, 2015, Jun-15, Volume: 308, Issue:12

    Topics: Adiposity; Animals; Behavior, Animal; Body Weight; Diet, High-Fat; Dihydrotestosterone; Disease Models, Animal; Energy Intake; Female; Glucose Intolerance; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Rats; Rats, Long-Evans; Stress, Psychological

2015
Anoctamin 1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Aug-04, Volume: 112, Issue:31

    Topics: Animals; Anoctamin-1; Calcium; Calcium Channels; Cell Proliferation; Chloride Channels; Chromatin Immunoprecipitation; Dihydrotestosterone; Disease Models, Animal; Epithelial Cells; Gene Knockdown Techniques; Genes, Reporter; Humans; Hyperplasia; Injections; Ion Channel Gating; Luciferases; Male; Neoplasm Proteins; Promoter Regions, Genetic; Prostate; Prostatic Hyperplasia; Rats, Wistar; Response Elements; RNA, Small Interfering; Tannins; Testosterone; Up-Regulation

2015
Neuroprotective Effect of Progesterone in MPTP-Treated Male Mice.
    Neuroendocrinology, 2016, Volume: 103, Issue:3-4

    Topics: Androstane-3,17-diol; Animals; Autoradiography; Brain; Carbon Radioisotopes; Cocaine; Dihydrotestosterone; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroprotective Agents; Progesterone; Testosterone; Vesicular Monoamine Transport Proteins

2016
The Influence of Dihydrotestosterone on the Development of Graves' Disease in Female BALB/c Mice.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:3

    Topics: Adenoviridae; Animals; Cytoprotection; Dihydrotestosterone; Disease Models, Animal; Female; Genetic Vectors; Graves Disease; Humans; Interferon-gamma; Interleukin-2; Mice, Inbred BALB C; Protective Agents; Receptors, Thyrotropin; Spleen; Th1 Cells; Th2 Cells; Thyroid Gland; Thyroid Hormones; Time Factors; Transduction, Genetic

2016
Sulforaphane promotes murine hair growth by accelerating the degradation of dihydrotestosterone.
    Biochemical and biophysical research communications, 2016, Mar-25, Volume: 472, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Alopecia; Animals; Cell Line; Dihydrotestosterone; Disease Models, Animal; Hair; Humans; Isothiocyanates; Kinetics; Liver; Male; Mice; Mice, Obese; RNA, Messenger; Sulfoxides; Testosterone

2016
Androgen and AR contribute to breast cancer development and metastasis: an insight of mechanisms.
    Oncogene, 2017, 05-18, Volume: 36, Issue:20

    Topics: Androgens; Animals; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Gene Knockdown Techniques; Histone Demethylases; Humans; Mice; Neoplasm Metastasis; Prognosis; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Vimentin; Xenograft Model Antitumor Assays

2017
Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms.
    Endocrinology, 2017, 03-01, Volume: 158, Issue:3

    Topics: Animals; Anovulation; Class Ia Phosphatidylinositol 3-Kinase; Cyclic AMP Response Element-Binding Protein; Dihydrotestosterone; Disease Models, Animal; Female; Forkhead Box Protein O1; Gluconeogenesis; Glucose Metabolism Disorders; Hepatocytes; Hyperandrogenism; Insulin Resistance; Liver; Mice, Inbred C57BL; Promoter Regions, Genetic; Receptors, Androgen

2017
Kisspeptin in the Hypothalamus of 2 Rat Models of Polycystic Ovary Syndrome.
    Endocrinology, 2017, 02-01, Volume: 158, Issue:2

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Gonadal Steroid Hormones; Gonadotropins; Hypothalamo-Hypophyseal System; Hypothalamus, Anterior; Kisspeptins; Ovary; Phenotype; Polycystic Ovary Syndrome; Rats, Wistar

2017
Stable Isotope Labeling with Amino Acids (SILAC)-Based Proteomics of Primary Human Kidney Cells Reveals a Novel Link between Male Sex Hormones and Impaired Energy Metabolism in Diabetic Kidney Disease.
    Molecular & cellular proteomics : MCP, 2017, Volume: 16, Issue:3

    Topics: Animals; Cells, Cultured; Cytokines; Diabetic Nephropathies; Dihydrotestosterone; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Glucose-6-Phosphate Isomerase; Humans; Isotope Labeling; Kidney; Male; Mice; Mitochondrial Trifunctional Protein, alpha Subunit; Oxidative Stress; Proteomics; Transferases (Other Substituted Phosphate Groups)

2017
The effect of transarterial prostate embolization in hormone-induced benign prostatic hyperplasia in dogs: a pilot study.
    Journal of vascular and interventional radiology : JVIR, 2009, Volume: 20, Issue:3

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Dogs; Embolization, Therapeutic; Estradiol; Feasibility Studies; Hormones; Humans; Hyperplasia; Male; Pilot Projects; Polyvinyl Alcohol; Prostate; Treatment Outcome

2009
Acupuncture and exercise restore adipose tissue expression of sympathetic markers and improve ovarian morphology in rats with dihydrotestosterone-induced PCOS.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: Acupuncture Therapy; Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Exercise Therapy; Female; Gene Expression Regulation; Nerve Growth Factor; Neuropeptide Y; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Adrenergic, beta-3; Receptors, Androgen; RNA, Messenger; Sympathetic Nervous System

2009
Sex steroids during bone growth: a comparative study between mouse models for hypogonadal and senile osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:10

    Topics: Absorptiometry, Photon; Aging; Amino Acids; Animals; Bone Development; Dihydrotestosterone; Disease Models, Animal; Estradiol; Gonadal Steroid Hormones; Hormone Replacement Therapy; Hypogonadism; Male; Mice; Orchiectomy; Osteocalcin; Osteoporosis; Phenotype; Tomography, X-Ray Computed

2009
Depression-like behavior of aged male and female mice is ameliorated with administration of testosterone or its metabolites.
    Physiology & behavior, 2009, May-25, Volume: 97, Issue:2

    Topics: Aging; Analysis of Variance; Androgens; Animals; Anxiety Disorders; Behavior, Animal; Dihydrotestosterone; Disease Models, Animal; Female; Immobility Response, Tonic; Male; Mice; Mice, Inbred C57BL; Swimming; Testosterone

2009
Dose-dependent effects of androgens on outcome after focal cerebral ischemia in adult male mice.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:8

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Behavior, Animal; Brain Ischemia; Castration; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Receptors, Androgen; Sex Characteristics; Testosterone

2009
Inflammation and epithelial alterations in rat prostate: impact of the androgen to oestrogen ratio.
    International journal of andrology, 2009, Volume: 32, Issue:4

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Fos-Related Antigen-2; Hormone Replacement Therapy; Ki-67 Antigen; Male; Orchiectomy; Organ Size; Pituitary Gland; Prolactin; Prostate; Prostatitis; Rats; Receptors, Progesterone; Seminal Vesicles; Testosterone

2009
Testosterone and dihydrotestosterone differentially improve cognition in aged female mice.
    Learning & memory (Cold Spring Harbor, N.Y.), 2009, Volume: 16, Issue:8

    Topics: Androgens; Animals; Avoidance Learning; Cognition Disorders; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Exploratory Behavior; Female; Male; Matched-Pair Analysis; Maze Learning; Mental Recall; Mice; Mice, Inbred C57BL; Sex Factors; Spatial Behavior; Statistics, Nonparametric; Testosterone

2009
Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice.
    Reproductive biology and endocrinology : RB&E, 2009, Aug-27, Volume: 7

    Topics: Androgens; Animals; Cryptorchidism; Dihydrotestosterone; Disease Models, Animal; Female; Gonadotropins; Humans; Hypogonadism; Lithiasis; Male; Mice; Mice, Knockout; Receptors, Androgen; Sertoli Cells; Testicular Diseases; Testis; Testosterone

2009
Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neuroactive steroid levels.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: 20-alpha-Dihydroprogesterone; Acute Disease; Androstane-3,17-diol; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Male; Mass Spectrometry; Multiple Sclerosis; Neurotransmitter Agents; Pregnanolone; Progesterone; Rats; Sex Characteristics; Testosterone

2010
Effects of electrical stimulation and gonadal steroids on rat facial nerve regenerative properties.
    Restorative neurology and neuroscience, 2009, Volume: 27, Issue:6

    Topics: Animals; Axotomy; Dihydrotestosterone; Disease Models, Animal; Electric Stimulation; Estradiol; Facial Nerve Diseases; Leucine; Lysine; Male; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Steroids; Testosterone Propionate; Time Factors; Tritium

2009
Endocrine traits of polycystic ovary syndrome in prenatally androgenized female Sprague-Dawley rats.
    Endocrine journal, 2010, Volume: 57, Issue:3

    Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Hypothalamus; Luteinizing Hormone; Nipples; Ovarian Follicle; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; RNA, Messenger; Testosterone

2010
A mouse model of androgenetic alopecia.
    Endocrinology, 2010, Volume: 151, Issue:5

    Topics: Alopecia; Androgen Antagonists; Androgens; Animals; beta Catenin; Blotting, Western; Cell Line; Cell Line, Tumor; Dihydrotestosterone; Disease Models, Animal; Female; Flutamide; Hair; Humans; Keratin-5; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Promoter Regions, Genetic; Protein Binding; Receptors, Androgen; Transfection

2010
Is the "comb over" dying? A mouse model for male pattern baldness (androgenic alopecia).
    Endocrinology, 2010, Volume: 151, Issue:5

    Topics: Alopecia; Androgen Antagonists; Androgens; Animals; beta Catenin; Dihydrotestosterone; Disease Models, Animal; Flutamide; Hair Follicle; Humans; Mice; Mice, Transgenic; Models, Biological; Protein Binding; Receptors, Androgen; Testosterone

2010
Temporary placement of a covered, retrievable, barbed stent for the treatment of hormone-induced benign prostatic hyperplasia: technical feasibility and histologic changes in canine prostates.
    Journal of vascular and interventional radiology : JVIR, 2010, Volume: 21, Issue:9

    Topics: Animals; Atrophy; Coated Materials, Biocompatible; Device Removal; Dihydrotestosterone; Disease Models, Animal; Dogs; Estradiol; Feasibility Studies; Fibrosis; Male; Prostate; Prostatic Hyperplasia; Prosthesis Design; Radiography; Stents; Time Factors; Urethra; Urethral Obstruction

2010
Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways.
    Brain research, 2010, Nov-04, Volume: 1359

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Dihydrotestosterone; Disease Models, Animal; Estradiol; Immunohistochemistry; Male; Mice; Mice, Transgenic; Phosphorylation; Signal Transduction; tau Proteins; Testosterone

2010
Androgens alter brain catecholamine content and blood pressure in the testicular feminized male rat.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:2

    Topics: Androgen-Insensitivity Syndrome; Androgens; Animals; Blood Pressure; Brain; Catecholamines; Dihydrotestosterone; Disease Models, Animal; Female; Male; Orchiectomy; Rats; Rats, Inbred SHR; Rats, Mutant Strains; Receptors, Androgen; Testosterone

2011
Oral exposure to low-dose bisphenol A aggravates testosterone-induced benign hyperplasia prostate in rats.
    Toxicology and industrial health, 2011, Volume: 27, Issue:9

    Topics: Administration, Oral; Animals; Benzhydryl Compounds; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Endocrine Disruptors; Epithelial Cells; Estradiol; Estrogens, Non-Steroidal; Male; Organ Size; Phenols; Prolactin; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Testosterone

2011
Cardiovascular-renal and metabolic characterization of a rat model of polycystic ovary syndrome.
    Gender medicine, 2011, Volume: 8, Issue:2

    Topics: Angiotensinogen; Animals; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Glomerular Filtration Rate; Glucose Tolerance Test; Kidney Diseases; Leptin; Metabolic Syndrome; Oxidative Stress; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System

2011
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Sep-15, Volume: 17, Issue:18

    Topics: Alternative Splicing; Androgens; Androstenes; Androstenols; Animals; Biosynthetic Pathways; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, SCID; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Xenograft Model Antitumor Assays

2011
The effect of vertical sleeve gastrectomy on a rat model of polycystic ovarian syndrome.
    Endocrinology, 2011, Volume: 152, Issue:10

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Gastrectomy; Male; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Weight Loss

2011
Effects of androgen and leptin on behavioral and cellular responses in female rats.
    Hormones and behavior, 2011, Volume: 60, Issue:4

    Topics: Androgens; Animals; Behavior, Animal; Body Weight; Brain; Cell Physiological Phenomena; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Leptin; Maze Learning; Organ Size; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Androgen

2011
The antidepressant-like effects of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane in mice is related to changes in neuroactive steroid and monoamine levels.
    Neuropharmacology, 2012, Volume: 62, Issue:1

    Topics: Adrenalectomy; Analysis of Variance; Animals; Anxiety, Castration; Biogenic Monoamines; Brain; Depression; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Male; Mice; Radioimmunoassay; Steroids; Swimming; Time Factors

2012
Effects of topical application of EGCG on testosterone-induced hair loss in a mouse model.
    Experimental dermatology, 2011, Volume: 20, Issue:12

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Alopecia; Animals; Antioxidants; Apoptosis; Catechin; Cyproterone Acetate; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Epithelial Cells; Female; Hair; Hair Follicle; Mice; Mice, Inbred CBA; Receptors, Androgen; Sebaceous Glands; Testosterone

2011
Arteriolar insulin resistance in a rat model of polycystic ovary syndrome.
    Fertility and sterility, 2012, Volume: 97, Issue:2

    Topics: Acetylcholine; Animals; Arterioles; Blood Glucose; Cholecalciferol; Dihydrotestosterone; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose Tolerance Test; Insulin; Insulin Resistance; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

2012
Influence of sex hormones and genetic predisposition in Sjögren's syndrome: a new clue to the immunopathogenesis of dry eye disease.
    Experimental eye research, 2012, Volume: 96, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Genetic Predisposition to Disease; Immunohistochemistry; In Situ Nick-End Labeling; Lacrimal Apparatus; Leukocyte Common Antigens; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Ovariectomy; Sjogren's Syndrome

2012
Effects of Melandrium firmum methanolic extract on testosterone-induced benign prostatic hyperplasia in Wistar rats.
    Asian journal of andrology, 2012, Volume: 14, Issue:2

    Topics: Administration, Oral; Animals; Caryophyllaceae; Dihydrotestosterone; Disease Models, Animal; Male; Methanol; Orchiectomy; Organ Size; Plant Extracts; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Testosterone

2012
Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:3-4

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Male; Organ Size; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2012
Estrogen receptor-α mediates diethylstilbestrol-induced feminization of the seminal vesicle in male mice.
    Environmental health perspectives, 2012, Volume: 120, Issue:4

    Topics: Androgens; Animals; Blotting, Western; Castration; Diethylstilbestrol; Dihydrotestosterone; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Feminization; Gene Expression; Lactoferrin; Male; Mice; Mice, Knockout; Radioimmunoassay; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminal Vesicle Secretory Proteins; Seminal Vesicles

2012
Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats.
    American journal of physiology. Renal physiology, 2012, May-01, Volume: 302, Issue:9

    Topics: Albuminuria; Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Dihydrotestosterone; Disease Models, Animal; Estrogen Receptor alpha; Incidence; Male; Nitriles; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Streptozocin; Triazoles; Tumor Necrosis Factor-alpha

2012
Reproductive and metabolic phenotype of a mouse model of PCOS.
    Endocrinology, 2012, Volume: 153, Issue:6

    Topics: Adiponectin; Animals; Body Weight; Dihydrotestosterone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Humans; Immunohistochemistry; Insulin; Leptin; Lipid Metabolism; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Ovarian Follicle; Ovary; Phenotype; Polycystic Ovary Syndrome; Reproduction; Reverse Transcriptase Polymerase Chain Reaction

2012
Electrical and manual acupuncture stimulation affect oestrous cyclicity and neuroendocrine function in an 5α-dihydrotestosterone-induced rat polycystic ovary syndrome model.
    Experimental physiology, 2012, Volume: 97, Issue:5

    Topics: Acupuncture Therapy; Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Disease Models, Animal; Electroacupuncture; Estrous Cycle; Female; Polycystic Ovary Syndrome; Progesterone; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Testosterone

2012
Effects of oral finasteride on erectile function in a rat model.
    The journal of sexual medicine, 2012, Volume: 9, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Animals; Dihydrotestosterone; Disease Models, Animal; Erectile Dysfunction; Finasteride; Male; Penile Erection; Penis; Prostate; Rats; Rats, Sprague-Dawley; Testosterone

2012
Inhibitory effect of Yukmijihwang-tang, a traditional herbal formula against testosterone-induced benign prostatic hyperplasia in rats.
    BMC complementary and alternative medicine, 2012, Apr-20, Volume: 12

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Testosterone

2012
Dihydrotestosterone ameliorates degeneration in muscle, axons and motoneurons and improves motor function in amyotrophic lateral sclerosis model mice.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Androgens; Animals; Axons; Body Weight; Dihydrotestosterone; Disease Models, Animal; Gene Expression; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Neurons; Motor Skills; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Neuromuscular Junction; Neuroprotective Agents; Superoxide Dismutase; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

2012
Pharmacological reactivity of resistance vessels in a rat PCOS model - vascular effects of parallel vitamin D₃ treatment.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:12

    Topics: Animals; Arterioles; Cardiovascular Agents; Cardiovascular Diseases; Cholecalciferol; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Endothelium, Vascular; Female; Injections, Subcutaneous; Muscle, Skeletal; Muscle, Smooth, Vascular; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Thigh; Vascular Resistance; Vasoconstriction; Vasodilation

2012
Androgen initiates Sertoli cell tight junction formation in the hypogonadal (hpg) mouse.
    Biology of reproduction, 2012, Volume: 87, Issue:2

    Topics: Androgens; Animals; Connexins; Dihydrotestosterone; Disease Models, Animal; Follicle Stimulating Hormone; Humans; Hypogonadism; Male; Mice; Mice, Transgenic; Organ Size; Rats; RNA, Messenger; Sertoli Cells; Tight Junctions

2012
Physical exercise on the rat ventral prostate: steroid hormone receptors, apoptosis and cell proliferation.
    Scandinavian journal of medicine & science in sports, 2012, Volume: 22, Issue:5

    Topics: Animals; Apoptosis; Cell Proliferation; Corticosterone; Dihydrotestosterone; Disease Models, Animal; Estradiol; Gonadal Steroid Hormones; Male; Physical Conditioning, Animal; Prostate; Prostatic Diseases; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone

2012
Chemerin, a novel regulator of follicular steroidogenesis and its potential involvement in polycystic ovarian syndrome.
    Endocrinology, 2012, Volume: 153, Issue:11

    Topics: Adipokines; Animals; Aromatase; Chemokines; Cholesterol Side-Chain Cleavage Enzyme; Dihydrotestosterone; Disease Models, Animal; Female; Follicle Stimulating Hormone; Gene Expression; Gonadal Steroid Hormones; Granulosa Cells; Intercellular Signaling Peptides and Proteins; Ovarian Follicle; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Steroidogenic Factor 1

2012
Altered insulin-induced relaxation of aortic rings in a dihydrotestosterone-induced rodent model of polycystic ovary syndrome.
    Fertility and sterility, 2013, Volume: 99, Issue:2

    Topics: Animals; Aorta; Dihydrotestosterone; Disease Models, Animal; Female; Humans; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Vasodilation; Vitamin D

2013
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Acupuncture Therapy; Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Electric Stimulation; Female; Glucose; Humans; Insulin; Muscle Contraction; Muscle, Skeletal; Musculoskeletal Manipulations; Polycystic Ovary Syndrome; Rats; Signal Transduction

2013
[Effect of prenatal hyperandrogenism during pregnancy and on postnatal development of rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2002, Volume: 48, Issue:3

    Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Embryonic and Fetal Development; Female; Hyperandrogenism; Male; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reproduction; Sexual Maturation; Testosterone

2002
Genistein alters growth but is not toxic to the rat prostate.
    The Journal of nutrition, 2002, Volume: 132, Issue:10

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen-Binding Protein; Animals; Anticarcinogenic Agents; Diethylstilbestrol; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Genistein; Glycine max; Growth Inhibitors; Humans; Isoflavones; Male; Organ Size; Phytoestrogens; Plant Preparations; Prostate; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone

2002
Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:11

    Topics: Aging; Anabolic Agents; Animals; Body Composition; Bone Density; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Male; Orchiectomy; Osteoporosis; Rats

2002
MicroPET assessment of androgenic control of glucose and acetate uptake in the rat prostate and a prostate cancer tumor model.
    Nuclear medicine and biology, 2002, Volume: 29, Issue:8

    Topics: Acetates; Androgen Antagonists; Androgens; Animals; Carbon; Diethylstilbestrol; Dihydrotestosterone; Disease Models, Animal; Fluorodeoxyglucose F18; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Nude; Neoplasm Transplantation; Organ Specificity; Prostate; Prostatic Neoplasms; Radiopharmaceuticals; Rats; Tissue Distribution; Tomography, Emission-Computed

2002
[Establishment of prostatic hyperplasia model with castration beagle canines].
    Zhonghua nan ke xue = National journal of andrology, 2003, Volume: 9, Issue:6

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Dogs; Male; Orchiectomy; Prostatic Hyperplasia; Testosterone Propionate

2003
Bone anabolic effects of S-40503, a novel nonsteroidal selective androgen receptor modulator (SARM), in rat models of osteoporosis.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:11

    Topics: Anabolic Agents; Animals; Bone and Bones; Bone Density; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Osteoporosis; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Androgen

2003
Effect of sex hormones on experimental autoimmune uveoretinitis (EAU).
    Immunological investigations, 2003, Volume: 32, Issue:4

    Topics: Animals; Autoimmune Diseases; Dihydrotestosterone; Disease Models, Animal; Estradiol; Eye Proteins; Female; Gene Expression; Gonadal Steroid Hormones; Immunodominant Epitopes; Interferon-gamma; Interleukin-10; Male; Orchiectomy; Ovariectomy; Progesterone; Rats; Rats, Inbred Lew; Retinitis; Retinol-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors; Uveitis; Vaccination

2003
Functional and anatomical effects of hormonally induced experimental prostate growth: a urodynamic model of benign prostatic hyperplasia (BPH) in the beagle.
    The Prostate, 2004, Feb-01, Volume: 58, Issue:2

    Topics: Age Factors; Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Estradiol; Humans; Male; Pressure; Prostatic Hyperplasia; Urethral Obstruction; Urination Disorders; Urodynamics

2004
Physiological levels of 5 alpha-dihydrotestosterone depress wound immune function and impair wound healing following trauma-hemorrhage.
    Archives of surgery (Chicago, Ill. : 1960), 2004, Volume: 139, Issue:2

    Topics: Analysis of Variance; Animals; Castration; Cytokines; Dihydrotestosterone; Disease Models, Animal; Immunity, Cellular; Immunohistochemistry; Male; Mice; Mice, Inbred C3H; Probability; Random Allocation; Reference Values; Sensitivity and Specificity; Shock, Hemorrhagic; Wound Healing; Wounds and Injuries

2004
Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Animals; Aromatase; Attention Deficit Disorder with Hyperactivity; Capillaries; Cerebrovascular Circulation; Dihydrotestosterone; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Frontal Lobe; Gonadal Steroid Hormones; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Stroke; Testosterone; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2004
Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells.
    International journal of cancer, 2004, Aug-20, Volume: 111, Issue:2

    Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cyclooxygenase 2; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Disease Progression; Eicosanoic Acids; gamma-Linolenic Acid; Humans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Tumor Cells, Cultured

2004
Matrix metalloproteinases in the pathogenesis of estradiol-induced nonbacterial prostatitis in the lateral prostate lobe of the Wistar rat.
    Experimental and molecular pathology, 2004, Volume: 77, Issue:1

    Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Drug Therapy, Combination; Estradiol; Male; Matrix Metalloproteinases; Orchiectomy; Organ Size; Prostate; Prostatitis; Rats; Rats, Wistar; Testosterone Propionate

2004
Effects of estradiol and dihydrotestosterone on osteoblast gene expression in osteopenic ovariectomized rats.
    Journal of bone and mineral metabolism, 2005, Volume: 23, Issue:3

    Topics: Animals; Bone Diseases, Metabolic; Calcium; Creatine; Dihydrotestosterone; Disease Models, Animal; Drug Therapy, Combination; Estradiol; Female; Gene Expression Regulation; Osteoblasts; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin

2005
Gonadal steroid attenuation of developing hamster facial motoneuron loss by axotomy: equal efficacy of testosterone, dihydrotestosterone, and 17-beta estradiol.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-20, Volume: 25, Issue:16

    Topics: Age Factors; Animals; Animals, Newborn; Axotomy; Brain Stem; Cell Count; Cell Death; Cricetinae; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Facial Nerve Injuries; Female; Functional Laterality; Gene Expression Regulation, Developmental; Gonadal Steroid Hormones; Immunohistochemistry; Male; Mesocricetus; Motor Neurons; Receptors, Androgen; Sex Factors; Testosterone

2005
Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:7

    Topics: Androgen Antagonists; Animals; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Disease Progression; eIF-2 Kinase; Female; Flutamide; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins B-raf; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Sex Factors; Signal Transduction; Testosterone Congeners

2005
Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jul-01, Volume: 12, Issue:13

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Administration, Oral; Animals; Azasteroids; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Dihydrotestosterone; Disease Models, Animal; Dutasteride; Enzyme Activation; Enzyme Inhibitors; Finasteride; Gene Expression Profiling; Humans; Male; Mass Spectrometry; Mice; Mice, Nude; Molecular Conformation; Prostatic Neoplasms; Protein Isoforms; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2006
[Pharmacological and clinical profile of finasteride (PROPECIA)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006, Volume: 127, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Alopecia; Animals; Clinical Trials as Topic; Dihydrotestosterone; Disease Models, Animal; Enzyme Inhibitors; Female; Finasteride; Haplorhini; Humans; Male

2006
Effects of dietary saw palmetto on the prostate of transgenic adenocarcinoma of the mouse prostate model (TRAMP).
    The Prostate, 2007, May-01, Volume: 67, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgen Antagonists; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diet; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organ Size; Plant Extracts; Prostate; Prostatic Neoplasms; Serenoa; Testosterone

2007
A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome.
    Endocrinology, 2007, Volume: 148, Issue:8

    Topics: Adipocytes; Androgens; Animals; Aromatase Inhibitors; Body Composition; Body Weight; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Letrozole; Magnetic Resonance Imaging; Mesentery; Muscle, Skeletal; Nitriles; Organ Size; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Testosterone; Triazoles

2007
Effects of dutasteride on prostate growth in the large probasin-large T antigen mouse model of prostate cancer.
    The Journal of urology, 2007, Volume: 178, Issue:4 Pt 1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Animals; Antigens, Viral, Tumor; Apoptosis; Azasteroids; Cell Division; Cell Transformation, Neoplastic; Dihydrotestosterone; Disease Models, Animal; Dutasteride; Enzyme Inhibitors; Female; Male; Membrane Proteins; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Seminal Vesicles; Transgenes

2007
Gender differences and protective effects of testosterone in collagen induced arthritis in rats.
    Rheumatology international, 2008, Volume: 28, Issue:4

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Autoantibodies; Collagen Type II; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Female; Joints; Lipid Peroxidation; Lysosomes; Male; Orchiectomy; Rats; Rats, Wistar; Severity of Illness Index; Sex Factors; Testosterone; Time Factors

2008
The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction--an evaluation using primates, rabbit and rat.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:1-2

    Topics: Administration, Oral; Animals; Blood Pressure; Castration; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Erectile Dysfunction; Injections, Subcutaneous; Macaca mulatta; Male; Papio anubis; Phytotherapy; Plant Extracts; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Testosterone; Tribulus

2008
Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus.
    Experimental neurology, 2008, Volume: 210, Issue:2

    Topics: Analysis of Variance; Androgen Antagonists; Androgens; Animals; Animals, Newborn; Brain Damage, Chronic; Calcium; Cells, Cultured; Dihydrotestosterone; Disease Models, Animal; Drug Interactions; Female; Flutamide; GABA Agents; Genetic Predisposition to Disease; Hippocampus; In Situ Nick-End Labeling; Male; Neurons; Rats; Receptors, GABA-A; Sex Characteristics

2008
Androgen increases AT1a receptor expression in abdominal aortas to promote angiotensin II-induced AAAs in apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:7

    Topics: Androgens; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Ovariectomy; Receptor, Angiotensin, Type 1; RNA, Messenger; Sex Factors; Time Factors; Up-Regulation

2008
The polycystic ovary syndrome and experimental models for the study of its pathogenesis.
    Progress in clinical and biological research, 1982, Volume: 112 Pt A

    Topics: Age Factors; Androgens; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Disease Models, Animal; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Gonadotropins, Pituitary; Hirsutism; Humans; Ovarian Cysts; Ovary; Ovulation; Rats

1982
Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:4

    Topics: Acne Vulgaris; Adult; Animals; Dihydrotestosterone; Disease Models, Animal; Face; Female; Graft Survival; Humans; Hydrocarbons, Chlorinated; Hyperplasia; Male; Mice; Mice, Nude; Middle Aged; Models, Biological; Naphthalenes; Sebaceous Glands; Skin; Skin Physiological Phenomena; Skin Transplantation; Testosterone

1984
Effects of a new steroidal antiandrogen, TZP-4238 (17 alpha-acetoxy-6-chloro-2-oxa-4, 6-pregnadiene-3, 20-dione), on spontaneously developed canine benign prostatic hyperplasia.
    The Prostate, 1995, Volume: 27, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Animals; Chlormadinone Acetate; Contraceptives, Oral; Dihydrotestosterone; Disease Models, Animal; Dogs; Male; Organ Size; Prostate; Prostatic Hyperplasia; Receptors, Androgen; Testosterone; Ultrasonography

1995
The requirement of the testis in establishing the sensitivity of the canine prostate to develop benign prostatic hyperplasia.
    The Journal of urology, 1994, Volume: 152, Issue:3

    Topics: Aging; Animals; Atrophy; Dihydrotestosterone; Disease Models, Animal; Dogs; Estradiol; Male; Prostate; Prostatic Hyperplasia; Testis; Testosterone

1994
Induction of benign prostatic hyperplasia in intact dogs by near-physiological levels of 5 alpha-dihydrotestosterone and 17 beta-estradiol.
    The Prostate, 1995, Volume: 26, Issue:6

    Topics: Analysis of Variance; Animals; Dihydrotestosterone; Disease Models, Animal; Dogs; Estradiol; Male; Prostatic Hyperplasia

1995
Dehydroepiandrosterone reduces progressive dermal ischemia caused by thermal injury.
    The Journal of surgical research, 1995, Volume: 59, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Animals; Back; Burns; Dehydroepiandrosterone; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Estradiol; Ischemia; Male; Mice; Mice, Inbred BALB C; Necrosis; Random Allocation; Skin; Time Factors

1995
Benign prostatic hyperplasia in a transgenic mouse: a new hormonally sensitive investigatory model.
    The Journal of urology, 1993, Volume: 149, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Androstenes; Animals; Azasteroids; Dihydrotestosterone; Disease Models, Animal; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Finasteride; Flutamide; Genes, Viral; Male; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Orchiectomy; Phenotype; Prostate; Prostatic Hyperplasia; Proto-Oncogene Proteins; Sexual Maturation; Testosterone

1993
Sex differences in inflammation induced cartilage damage in rodents. The influence of sex steroids.
    The Journal of rheumatology, 1994, Volume: 21, Issue:2

    Topics: Animals; Arthritis; Cartilage, Articular; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Gonadal Steroid Hormones; Granuloma; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Receptors, Androgen; Receptors, Estrogen; Sex Characteristics

1994
Effects of dihydrotestosterone alone and combined with estrogen on bone mineral density, bone growth, and formation rates in ovariectomized rats.
    Bone, 1996, Volume: 19, Issue:2

    Topics: Analysis of Variance; Animals; Body Weight; Bone Density; Bone Development; Bone Diseases, Metabolic; Dihydrotestosterone; Disease Models, Animal; Drug Therapy, Combination; Estradiol; Female; Ovariectomy; Ovary; Rats; Rats, Sprague-Dawley

1996
Effect of 5-alpha dihydrotestosterone on T-cell proliferation of the female nonobese diabetic mouse.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1996, Volume: 213, Issue:3

    Topics: Animals; CD4-Positive T-Lymphocytes; Diabetes Mellitus, Type 1; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression; Humans; Interleukin-2; Interleukin-4; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred NOD; Receptors, Interleukin-1; RNA, Messenger; T-Lymphocytes; Th2 Cells

1996
Effects of topical antiandrogen and 5-alpha-reductase inhibitors on sebaceous glands in male fuzzy rats.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1997, Volume: 10, Issue:5-6

    Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Androgen Antagonists; Animals; Bromodeoxyuridine; Dermatitis, Seborrheic; Dihydrotestosterone; Disease Models, Animal; Enzyme Inhibitors; Male; Organ Size; Rats; Rats, Mutant Strains; Sebaceous Glands; Testosterone

1997
Chronology and urodynamic characterization of micturition in neurohormonally induced experimental prostate growth in the rat.
    Neurourology and urodynamics, 1998, Volume: 17, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Chronic Disease; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Drug Combinations; Follow-Up Studies; Male; Muscle Contraction; Organ Size; Prazosin; Prostate; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Ureter; Urinary Bladder Neck Obstruction; Urodynamics

1998
Testosterone and/or low estradiol: normally required but harmful immunologically for males after trauma-hemorrhage.
    The Journal of trauma, 1998, Volume: 44, Issue:1

    Topics: Animals; Corticosterone; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Injections, Subcutaneous; Interleukin-1; Interleukin-6; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Radioimmunoassay; Random Allocation; Sex Characteristics; Shock, Hemorrhagic; Spleen; Wounds and Injuries

1998
Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines.
    The Prostate, 1999, Sep-01, Volume: 40, Issue:4

    Topics: Animals; Blotting, Western; Castration; Caveolin 1; Caveolins; Dihydrotestosterone; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Membrane Proteins; Mice; Mice, Nude; Prostate; Prostatic Neoplasms; Random Allocation; Tumor Cells, Cultured

1999
Expression of proinflammatory genes during estrogen-induced inflammation of the rat prostate.
    The Prostate, 2000, Jun-15, Volume: 44, Issue:1

    Topics: Animals; Chemokine CCL11; Chemokines, CC; Cytokines; Dihydrotestosterone; Disease Models, Animal; DNA; DNA Primers; Estradiol; Gene Expression Regulation; Histocytochemistry; Image Processing, Computer-Assisted; Interleukin-1; Interleukin-4; Interleukin-5; Interleukin-6; Male; Nitric Oxide Synthase; Prostate; Prostatitis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Necrosis Factor-alpha

2000
LNCaP progression model of human prostate cancer: androgen-independence and osseous metastasis.
    The Prostate, 2000, Jul-01, Volume: 44, Issue:2

    Topics: Animals; Blotting, Northern; Bone Neoplasms; Cell Line; Dihydrotestosterone; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gentian Violet; Histocytochemistry; Humans; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Karyotyping; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Orchiectomy; Osteosarcoma; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Neoplasm; Specific Pathogen-Free Organisms; Tumor Cells, Cultured

2000
Androgen dependency of hepatocarcinogenesis in TGFalpha transgenic mice.
    Liver, 2000, Volume: 20, Issue:3

    Topics: Animals; Blotting, Northern; Body Weight; Carcinoma, Hepatocellular; Cell Division; Dihydrotestosterone; Disease Models, Animal; Female; Gene Expression; Hormone Replacement Therapy; Leuprolide; Liver; Liver Neoplasms; Male; Mice; Mice, Transgenic; Orchiectomy; Organ Size; Proliferating Cell Nuclear Antigen; RNA, Messenger; Sex Characteristics; Testosterone; Transforming Growth Factor alpha

2000
In vivo model mimicking natural history of dog prostate cancer using DPC-1, a new canine prostate carcinoma cell line.
    The Prostate, 2001, Jan-01, Volume: 46, Issue:1

    Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Dihydrotestosterone; Disease Models, Animal; Dogs; Humans; Immunohistochemistry; Iodine Radioisotopes; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Prostatic Neoplasms; Radionuclide Imaging; Tumor Cells, Cultured

2001
Role of canine basal cells in prostatic post natal development, induction of hyperplasia, sex hormone-stimulated growth; and the ductal origin of carcinoma.
    The Prostate, 2001, May-15, Volume: 47, Issue:3

    Topics: Adenocarcinoma; Androstane-3,17-diol; Animals; Cell Division; Dihydrotestosterone; Disease Models, Animal; Dog Diseases; Dogs; Estradiol; Gonadal Steroid Hormones; Immunohistochemistry; Keratins; Ki-67 Antigen; Male; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen

2001
Immature ovaries and polycystic kidneys in the congenital polycystic kidney mouse may be due to abnormal sex steroid metabolism.
    Molecular and cellular endocrinology, 2001, May-15, Volume: 176, Issue:1-2

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrone; Fallopian Tubes; Female; Histocompatibility Antigens; Homozygote; Immunohistochemistry; Kidney; Liver; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Ovary; Oxidoreductases; Polycystic Kidney, Autosomal Recessive; Rats; Steroids; Superovulation; Testosterone

2001
Role of canine basal cells in postnatal prostatic development, induction of hyperplasia, and sex hormone-stimulated growth; and the ductal origin of carcinoma.
    The Prostate, 2001, Aug-01, Volume: 48, Issue:3

    Topics: Adenocarcinoma; Androstane-3,17-diol; Animals; Cell Division; Dihydrotestosterone; Disease Models, Animal; Dog Diseases; Dogs; Estradiol; Gonadal Steroid Hormones; Immunohistochemistry; Keratins; Ki-67 Antigen; Male; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen

2001
Decreased 5alpha-dihydrotestosterone catabolism suppresses T lymphocyte functions in males after trauma-hemorrhage.
    American journal of physiology. Cell physiology, 2002, Volume: 282, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Oxidoreductases; Animals; Castration; Cell Line; Dihydrotestosterone; Disease Models, Animal; Hemorrhage; Immune Tolerance; Interleukin-2; Interleukin-6; Male; Mice; Mice, Inbred C3H; Sex Factors; T-Lymphocytes; Wounds and Injuries

2002
The induction of prostatic hypertrophy in the dog with androstanediol.
    The Journal of clinical investigation, 1976, Volume: 57, Issue:4

    Topics: Androstane-3,17-diol; Androstanes; Animals; Castration; Dihydrotestosterone; Disease Models, Animal; Dogs; Estradiol; Estrone; Male; Prostatic Hyperplasia

1976
Characterization of a Wilms' tumor model.
    Investigative urology, 1975, Volume: 12, Issue:4

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Female; Kidney; Kidney Neoplasms; Male; Muscles; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Peritoneal Cavity; Rats; Sex Factors; Testosterone; Tissue Survival; Transplantation, Homologous; Wilms Tumor

1975
Delayed androgen treatment prolongs survival in murine lupus.
    The Journal of clinical investigation, 1979, Volume: 63, Issue:5

    Topics: Animals; Antibodies; Castration; Complement C3; Dihydrotestosterone; Disease Models, Animal; DNA; Female; Immunoglobulins; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mice

1979
Follicle-stimulating hormone plays a role in the induction of ovarian follicular cysts in hypophysectomized rats.
    Biology of reproduction, 1992, Volume: 47, Issue:2

    Topics: Androstenedione; Animals; Chorionic Gonadotropin; Cyclic AMP; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadotropins; Hypophysectomy; Ovarian Cysts; Ovary; Progesterone; Radioimmunoassay; Rats; Statistics as Topic; Testosterone; Time Factors

1992
Effects of androgens in models of rheumatoid arthritis.
    Agents and actions, 1992, Volume: 35, Issue:3-4

    Topics: Animals; Antigens; Arthritis, Rheumatoid; Cartilage, Articular; Collagen; Dexamethasone; Dihydrotestosterone; Disease Models, Animal; Female; Glycosaminoglycans; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Inbred Strains; Testosterone

1992
The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque.
    Journal of dermatological science, 1990, Volume: 1, Issue:3

    Topics: Alopecia; Animals; Blood Pressure; Body Weight; Diazoxide; Dihydrotestosterone; Disease Models, Animal; Female; Glucose; Hair; Heart Rate; Macaca; Male; Testosterone

1990
Uterine adenocarcinoma in mice following developmental treatment with estrogens: a model for hormonal carcinogenesis.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Diethylstilbestrol; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Endometriosis; Epithelium; Estradiol; Estrogens; Female; Hexestrol; Hyperplasia; Mice; Mice, Nude; Pregnancy; Prenatal Exposure Delayed Effects; Progesterone; Uterine Neoplasms; Uterus; Vagina

1990
High-density lipoprotein response to 5-alpha-dihydrotestosterone and testosterone in Macaca fascicularis: a hormone-responsive primate model for the study of atherosclerosis.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Androstanes; Animals; Arteriosclerosis; Azasteroids; Cholesterol, HDL; Dihydrotestosterone; Disease Models, Animal; Lipoproteins, HDL; Macaca fascicularis; Male; Orchiectomy; Testosterone

1990
Sex-hormone-induced inflammation and fibromuscular proliferation in the rat lateral prostate.
    The Prostate, 1988, Volume: 12, Issue:3

    Topics: Animals; Collagen; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Estradiol; Fibroblasts; Fibrosis; Inflammation; Male; Muscle, Smooth; Orchiectomy; Organ Size; Prostate; Prostatic Diseases; Prostatic Hyperplasia; Rats; Rats, Inbred Strains

1988
Prevention and treatment of experimental prostate cancer in Lobund-Wistar rats. I. Effects of estradiol, dihydrotestosterone, and castration.
    The Prostate, 1989, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Animals; Dihydrotestosterone; Disease Models, Animal; Estradiol; Germ-Free Life; Male; Neoplasm Staging; Orchiectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains

1989
The contribution of animal models to the understanding of endocrine management of prostate cancer. Effect of androgen and estrogen.
    Progress in clinical and biological research, 1985, Volume: 185A

    Topics: Animals; Castration; Colony-Forming Units Assay; Diethylstilbestrol; Dihydrotestosterone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Male; Neoplastic Stem Cells; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen; Stem Cells; Testosterone; Tumor Stem Cell Assay

1985
Prostatic carcinogenesis evoked by cellular interaction.
    Environmental health perspectives, 1988, Volume: 77

    Topics: Androgens; Animals; Dihydrotestosterone; Disease Models, Animal; Epithelium; Fibroblasts; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Tumor Cells, Cultured

1988
The effects of N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamide, a 5 alpha-reductase inhibitor and antiandrogen, on the development of baldness in the stumptail macaque.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 65, Issue:1

    Topics: Alopecia; Androgen Antagonists; Androstane-3,17-diol; Animals; Azasteroids; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Disease Models, Animal; Female; Hair; Macaca; Male; Oxidoreductases; Skin; Steroids, Heterocyclic; Testosterone

1987
Characterization of a hormone receptor defect in the androgen-insensitivity mutant.
    Cell, 1974, Volume: 3, Issue:1

    Topics: Androgen-Insensitivity Syndrome; Animals; Binding Sites; Castration; Centrifugation, Density Gradient; Cytosol; Dihydrotestosterone; Disease Models, Animal; Female; Glycerol; Kidney; Kidney Tubules, Proximal; Male; Mice; Mutation; Protein Binding; Receptors, Cell Surface; Sex Factors; Temperature

1974
Cytosol androgen receptor from kidney of normal and testicular feminized (Tfm) mice.
    Cell, 1974, Volume: 2, Issue:4

    Topics: Age Factors; Androgen-Insensitivity Syndrome; Androstanes; Animals; Binding Sites; Castration; Centrifugation, Density Gradient; Cytosol; Dihydrotestosterone; Disease Models, Animal; Female; Glycerol; Hot Temperature; Kidney; Kinetics; Male; Mice; Mice, Inbred BALB C; Progesterone; Protein Binding; Receptors, Cell Surface; Sex Factors; Tritium

1974
Animal model of human disease. Testicular feminization.
    The American journal of pathology, 1974, Volume: 76, Issue:3

    Topics: Adenoma; Androgen-Insensitivity Syndrome; Animals; Cytosol; Dihydrotestosterone; Disease Models, Animal; Female; Germ Cells; Humans; Karyotyping; Kidney; Luteinizing Hormone; Male; Mice; Middle Aged; Mutation; Neoplasms; Receptors, Drug; Sheep; Testicular Neoplasms; Testis; Testosterone

1974
Testosterone metabolism in the androgen-insensitive rat: a model for testicular feminization.
    Birth defects original article series, 1971, Volume: 7, Issue:6

    Topics: Adrenal Glands; Androgen-Insensitivity Syndrome; Animals; Carbon Radioisotopes; Cell Nucleus; Dihydrotestosterone; Disease Models, Animal; Disorders of Sex Development; Genes, Recessive; Leydig Cells; Male; Rats; Sex Chromosomes; Testis; Testosterone; Tritium

1971