Page last updated: 2024-08-21

dihydrotestosterone and Disease Exacerbation

dihydrotestosterone has been researched along with Disease Exacerbation in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (11.48)	18.2507
2000's	19 (31.15)	29.6817
2010's	30 (49.18)	24.3611
2020's	5 (8.20)	2.80

Authors

Authors	Studies
Akiba, K; Ariyasu, D; Aso, K; Hasegawa, Y; Nagamatsu, F	1
Chen, CW; Hsieh, RH; Lin, YL; Tsai, HH; Yu, PL	1
Chen, M; Cui, H; Li, S; Li, Y; Liu, X; Mi, S; Tang, L; Wang, X; Xu, S; Yu, H; Zhang, K; Zhang, Y	1
Atsumi, T; Cho, KY; Inoshita, N; Kamada, K; Kameda, H; Kenmotsu, Y; Konno, S; Miyoshi, H; Nakakubo, S; Nakamura, A; Nakamura, J; Nomoto, H; Sawamura, Y; Shimatsu, A; Sugino, H; Suzuki, M; Takahashi, Y; Yamashita, Y; Yuno, A	1
Ando, K; Anzai, N; Fujimoto, A; Hirota, T; Ichikawa, T; Ikehara, Y; Imamura, Y; Kanai, Y; Kaneda, A; Kanesaka, M; Maimaiti, M; Rii, J; Sakamoto, S; Shindo, N; Sugiura, M; Wakai, K; Xu, M; Yamada, Y	1
Carney, ST; Chen, Z; De Hoedt, A; Freedland, SJ; Grant, DJ; Howard, LE; Huang, J; Magyar, CE; Squires, J; Vidal, AC; Wiggins, E	1
Stone, L	1
Ishida, T; Miki, Y; Sasano, H; Suzuki, T; Takagi, K	1
English, RS	1
An, HJ; Jin, BR; Kim, HJ; Kim, MS; Lee, KH; Park, SK; Yoon, IJ	1
Hammes, SR; Levin, ER	1
Ciołczyk-Wierzbicka, D; Dulińska-Litewka, J; Gil, D; Laidler, P; Lekka, M; Zarzycka, M	1
Li, MX; Sun, LF; Xiao, TX; Yang, YL; Zhang, JV	1
Choi, KC; Go, RE; Hwang, KA; Jang, YG	1
Axcrona, K; Axcrona, U; Kvalheim, G; Liang, D; Liu, J; Ma, Y; Nesland, JM; Paus, E; Servoll, E; Suo, Z; Sæter, T; Vlatkovic, L; Waaler, G; Wen, JG; Yang, Y; Zhang, Z	1
Gao, L; He, M; Ni, X; Sun, Y; Tang, G; Wang, L; Xu, B; Yu, Y	1
Audenet, F; Basset, V; Branchereau, J; Lebret, T; Murez, T	1
Cui, H; Fan, P; Kang, L; Li, J; Li, S; Su, Y; Wang, L; Xing, Z	1
Corbo, GM; Di Marco Berardino, A; Inchingolo, R; Mancini, A; Raimondo, S; Smargiassi, A; Valente, S	1
Hollier, B; Jeet, V; Lehman, M; Nelson, C; Tevz, G	1
Belledant, A; Brisson, H; Caron, P; Fradet, Y; Garcia, L; Guillemette, C; Hovington, H; Lacombe, L; Lévesque, E; Simonyan, D; Têtu, B; Villeneuve, L	1
Mostaghel, EA; Plymate, S; Zhang, A; Zhang, J	1
Na, YG; Song, YT; Wang, XY; Wu, KJ; Yin, CM	1
An, HJ; Chung, KS; Jeon, HJ	1
Chattopadhyay, I; Gao, L; Gelman, IH; Holtz, R; Leach, RW; Qin, M; Vessella, RL; Wang, J	1
Butterfield, KT; Christenson, JL; Josan, JS; Katzenellenbogen, BS; Katzenellenbogen, JA; McDonnell, DP; Norris, JD; Pollock, JA; Richer, JK; Spoelstra, NS	1
Helenius, MA; Suikki, HE; Urbanucci, A; Visakorpi, T; Waltering, KK	1
Chen, HW; Gemo, AT; Guo, L; Kung, HJ; Revenko, AS; Tepper, CG; Zou, JX	1
Kim, J; Li, J	1
Bentov, I; Plymate, SR; Schayek, H; Sun, S; Werner, H	1
Adeniji, OO; Buttle, DJ; Chandrasekharan, S; Hamdy, FC; Molokwu, CN	1
Brandner, R; Djavan, B; Eckersberger, E; Espinosa, G; Finkelstein, J; Lepor, H; Sadri, H; Shah, O	1
Azzarello, JT; Culkin, DJ; Davis, JS; Dozmorov, MG; Fung, KM; Hurst, RE; Lin, HK; Penning, TM; Wren, JD; Yang, Q	1
Auchus, RJ; Chang, KH; Li, R; Papari-Zareei, M; Sharifi, N; Watumull, L; Zhao, YD	1
Borlak, J; Zwadlo, C	1
Campbell, TJ; Figg, WD; Tindall, DJ	1
Gao, GF; Guo, Y; Huhtaniemi, I; Li, D; Li, N; Li, X; Li, Z; Liu, Y; Rahman, N; Tsang, SY; Wang, L; Wu, J; Zhang, H	1
Arai, S; Hashimoto, K; Honma, S; Ito, K; Kashiwagi, B; Miyashiro, Y; Nakamura, Y; Sasano, H; Sekine, Y; Shibata, Y; Suzuki, K; Tomaru, Y; Uei, T	1
Balestrieri, A; Cappabianca, P; Carani, C; Colao, A; De Rosa, M; Di Sarno, A; Lombardi, G; Pivonello, R; Rochira, V	1
Fukabori, Y; Masuda, H; Nakano, K; Shimizu, N; Yamanaka, H	1
Banerjee, T; Pham, H; Ziboh, VA	1
Ji, H; Kim, J; Menini, S; Mok, K; Mulroney, S; Pesce, C; Sandberg, K; Zheng, W	1
Grantham, J; Kurahashi, H; Kusaka, M; Marunouchi, T; Nagao, S; Nishii, K; Takahashi, H	1
Abrahamsson, PA; Ahlgren, G; Gadaleanu, V; Giwercman, A; Giwercman, YL	1
Chai, KX; Chen, LM; Chen, M	1
Marks, LS	1
Benbrahim-Tallaa, L; Liu, J; Waalkes, MP; Webber, MM	1
Chung, MK; Emberton, M; Gittelman, M; Madersbacher, S; Michel, MC; Zinner, N	1
Hashimoto, Y; Ikarashi, T; Nishiyama, T; Takahashi, K; Wako, K	1
Arima, T; Chiyomaru, T; Enokida, H; Idesako, T; Kagara, I; Kubo, H; Matsuda, R; Nakagawa, M; Nishimura, H; Nishiyama, K; Tatarano, S; Toki, K	1
Rittmaster, RS; Tindall, DJ	1
Fung, KM; Lin, HK; Titus, MA; Yang, Q	1
Azcona-Olivera, JI; Greene, DM; Murtha, JM; Pestka, JJ	1
Igawa, M; Ishibe, T; Shiina, H	1
Brown, M; Chang, G; Dahl, DM; Febbo, PG; Giovannucci, E; Hennekens, CH; Kantoff, PW; Krithivas, K; Stampfer, MJ	1
Albino, AP; Bogenrieder, T; Finstad, CL; Freeman, R; Geng, Y; Magill, C; Nanus, DM; Papandreou, CN; Powell, CT; Reuter, VE; Scheinberg, D; Scher, HI; Usmani, B; Wilk, S	1
Constantinou, CE; Lee, JZ; Omata, S; Perkash, I; Tillig, B	1
Bennett, S; Berry, J; Downing, SR; Hill, MA; Joshua, A; Kingsley, EA; Mason, RS; Russell, PJ; Yu, Y	1
Cox, ME; Deeble, PD; Lakhani, S; Parsons, SJ	1
Gotoh, A; Keller, ET; Matsumoto, T; Mizokami, A; Yamada, H	1
Benghuzzi, HA; Pollan, MC; Tucci, M	1

Reviews

9 review(s) available for dihydrotestosterone and Disease Exacerbation

Article	Year
The interplay of endocrine therapy, steroid pathways and therapeutic resistance: Importance of androgen in breast carcinoma. Molecular and cellular endocrinology, 2018, 05-05, Volume: 466 Topics: Androgen Receptor Antagonists; Androgens; Animals; Aromatase; Breast Neoplasms; Dihydrotestosterone; Disease Progression; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Mice, Nude; Neoplasm Recurrence, Local; Receptors, Androgen	2018
Impact of estrogens in males and androgens in females. The Journal of clinical investigation, 2019, 05-01, Volume: 129, Issue:5 Topics: Androgens; Animals; Bone and Bones; Breast Neoplasms; Central Nervous System; Dihydrotestosterone; Disease Progression; Estradiol; Estrogens; Female; Genitalia; Humans; Male; Mice; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; Sex Factors; Testosterone	2019
[Qualitative and quantitative hormonal regulation in castration-resistant prostate cancer]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23 Suppl 1 Topics: Androgen Antagonists; Androgens; Antineoplastic Agents, Hormonal; Dihydrotestosterone; Disease Progression; Humans; Male; Neoplasm Recurrence, Local; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome	2013
Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression. Hormones & cancer, 2016, Volume: 7, Issue:2 Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Dihydrotestosterone; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Hydroxysteroid Dehydrogenases; Male; Minor Histocompatibility Antigens; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Racemases and Epimerases; Receptors, Androgen	2016
Molecular profiles of finasteride effects on prostate carcinogenesis. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:6 Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androgens; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azasteroids; Dihydrotestosterone; Disease Progression; Dutasteride; Epithelial Cells; Finasteride; Humans; Isoenzymes; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Patient Selection; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Stromal Cells	2009
Benign prostatic hyperplasia: current clinical practice. Primary care, 2010, Volume: 37, Issue:3 Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Cholinergic Antagonists; Dihydrotestosterone; Disease Progression; Humans; Male; Primary Health Care; Prostatic Hyperplasia; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Testosterone; Watchful Waiting	2010
Use of 5alpha-reductase inhibitors to prevent benign prostatic hyperplasia disease. Current urology reports, 2006, Volume: 7, Issue:4 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Biomarkers; Dihydrotestosterone; Disease Progression; Enzyme Inhibitors; Humans; Male; Prostate-Specific Antigen; Prostatic Hyperplasia; Quality of Life; United States; Urinary Retention	2006
Managing the progression of lower urinary tract symptoms/benign prostatic hyperplasia: therapeutic options for the man at risk. BJU international, 2007, Volume: 100, Issue:2 Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Dihydrotestosterone; Disease Progression; Humans; Male; Prostatic Hyperplasia; Prostatism; Risk Factors; Treatment Outcome	2007
The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer. The Journal of urology, 2008, Volume: 179, Issue:4 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Receptor Antagonists; Azasteroids; Dihydrotestosterone; Disease Progression; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Isoenzymes; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen	2008

Trials

1 trial(s) available for dihydrotestosterone and Disease Exacerbation

Article	Year
Short-term suppression of GH and IGF-I levels improves gonadal function and sperm parameters in men with acromegaly. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:9 Topics: Acromegaly; Adenoma; Adult; Androgen Antagonists; Dihydrotestosterone; Disease Progression; Estradiol; Follicle Stimulating Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Luteinizing Hormone; Male; Middle Aged; Peptides, Cyclic; Pituitary Neoplasms; Regression Analysis; Somatostatin; Sperm Count; Sperm Motility; Testosterone	2002

Article

Year

Short-term suppression of GH and IGF-I levels improves gonadal function and sperm parameters in men with acromegaly.

The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:9

Topics: Acromegaly; Adenoma; Adult; Androgen Antagonists; Dihydrotestosterone; Disease Progression; Estradiol; Follicle Stimulating Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Luteinizing Hormone; Male; Middle Aged; Peptides, Cyclic; Pituitary Neoplasms; Regression Analysis; Somatostatin; Sperm Count; Sperm Motility; Testosterone

2002

Other Studies

51 other study(ies) available for dihydrotestosterone and Disease Exacerbation

Article	Year
Longitudinal clinical course in patients with 5α-reductase type 2 deficiency treated with testosterone and dihydrotestosterone during infancy and puberty. Endocrine journal, 2023, Jan-30, Volume: 70, Issue:1 Topics: Adult; Dihydrotestosterone; Disease Progression; Humans; Infant; Male; Oxidoreductases; Puberty; Testosterone	2023
Mangosteen pericarp components alleviate progression of prostatic hyperplasia and mitochondrial dysfunction in rats. Scientific reports, 2020, 01-15, Volume: 10, Issue:1 Topics: Animals; Body Weight; Diet, High-Fat; Dietary Supplements; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Garcinia mangostana; Male; Malondialdehyde; Mitochondria; Nitric Oxide Synthase Type II; Oxidative Stress; Plant Extracts; Proliferating Cell Nuclear Antigen; Prostate; Prostatic Hyperplasia; Rats; Rats, Inbred F344; Testosterone	2020
Association of Androgens and Gonadotropins with Amnestic Mild Cognitive Impairment and Probable Alzheimer's Disease in Chinese Elderly Men. Journal of Alzheimer's disease : JAD, 2020, Volume: 78, Issue:1 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Androgens; Apolipoproteins E; Biomarkers; China; Cognition; Cognitive Dysfunction; Dihydrotestosterone; Disease Progression; Genotype; Gonadotropins; Humans; Male; Neuropsychological Tests; Testosterone	2020
Successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. Endocrine journal, 2021, Apr-28, Volume: 68, Issue:4 Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Amides; Benzamidines; Combined Modality Therapy; COVID-19; Dihydrotestosterone; Disease Progression; Female; Guanidines; Health Personnel; Heparin; Humans; Japan; Metyrapone; Neurosurgical Procedures; Pituitary ACTH Hypersecretion; Pregnenediones; Pyrazines; SARS-CoV-2; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination	2021
Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor. Cancer science, 2021, Volume: 112, Issue:9 Topics: Aged; Amino Acid Transport System y+L; Amino Acid Transport Systems, Basic; Cell Movement; Cell Proliferation; Cell Survival; Cohort Studies; Dihydrotestosterone; Disease Progression; Gene Knockdown Techniques; Humans; Male; Middle Aged; Neoplasm Proteins; PC-3 Cells; Prognosis; Prostatectomy; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Separase; Signal Transduction; TOR Serine-Threonine Kinases; Transfection	2021
UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression. BMC cancer, 2017, Jul-03, Volume: 17, Issue:1 Topics: Aged; Biomarkers; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Gene Expression; Glucuronosyltransferase; Humans; Immunohistochemistry; Isoenzymes; Male; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Recurrence; Retrospective Studies	2017
Prostate cancer: The pathway to progression: DHT biosynthesis. Nature reviews. Urology, 2017, Volume: 14, Issue:9 Topics: Dihydrotestosterone; Disease Progression; Humans; Male; Prostatectomy; Prostatic Neoplasms	2017
A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors. Medical hypotheses, 2018, Volume: 111 Topics: Alopecia; Androgens; Biomarkers; Dihydrotestosterone; Disease Progression; Estrogens; Female; Fibrosis; Hair; Hormone Replacement Therapy; Humans; Inflammation; Male; Models, Theoretical; Scalp; Transforming Growth Factor beta1	2018
Anti-Proliferative Effects of HBX-5 on Progression of Benign Prostatic Hyperplasia. Molecules (Basel, Switzerland), 2018, Oct-14, Volume: 23, Issue:10 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Cell Line; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Humans; Injections, Intramuscular; Male; Plant Extracts; Plants, Medicinal; Proliferating Cell Nuclear Antigen; Prostatic Hyperplasia; Rats; Receptors, Androgen; Testosterone Propionate	2018
Dihydrotestosterone increases the risk of bladder cancer in men. Human cell, 2019, Volume: 32, Issue:3 Topics: Cells, Cultured; Dihydrotestosterone; Disease Progression; Epithelial-Mesenchymal Transition; Eukaryotic Initiation Factor-4E; Gene Expression; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; Humans; Male; Molecular Targeted Therapy; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Risk; Sex Characteristics; Signal Transduction; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2019
Removal of DHT can relieve polycystic ovarian but not metabolic abnormalities in DHT-induced hyperandrogenism in mice. Reproduction, fertility, and development, 2019, Volume: 31, Issue:10 Topics: Adipose Tissue; Animals; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Female; Gene Expression; Hyperandrogenism; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Ovary; Polycystic Ovary Syndrome; Stimulation, Chemical; Time Factors	2019
Resveratrol inhibits DHT-induced progression of prostate cancer cell line through interfering with the AR and CXCR4 pathway. The Journal of steroid biochemistry and molecular biology, 2019, Volume: 192 Topics: Androgen Receptor Antagonists; Androgens; Antioxidants; Apoptosis; Cell Movement; Cell Proliferation; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Receptors, CXCR4; Resveratrol; Signal Transduction; Tumor Cells, Cultured	2019
SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas. PloS one, 2013, Volume: 8, Issue:7 Topics: Adult; Aged; Biomarkers; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Male; Middle Aged; Nanog Homeobox Protein; Neoplasm Grading; Neoplasm Staging; Neoplastic Stem Cells; Octamer Transcription Factor-3; Phenotype; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Sex Hormone-Binding Globulin; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Stem Cell Assay	2013
Effects of platelet-activating factor and its differential regulation by androgens and steroid hormones in prostate cancers. British journal of cancer, 2013, Sep-03, Volume: 109, Issue:5 Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Androgen Receptor Antagonists; Androgens; beta Catenin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclofenil; Dihydrotestosterone; Disease Progression; Estradiol; Hormone Antagonists; Humans; Imidazoles; Indoles; Male; Mifepristone; Platelet Activating Factor; Prostatic Neoplasms; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Wnt Proteins	2013
Dihydrotestosterone treatment delays the conversion from mild cognitive impairment to Alzheimer's disease in SAMP8 mice. Hormones and behavior, 2014, Volume: 65, Issue:5 Topics: Aging; Alzheimer Disease; Animals; Brain; CA1 Region, Hippocampal; Cognitive Dysfunction; Dihydrotestosterone; Disease Progression; Female; Male; Maze Learning; Mice; Species Specificity; Testosterone	2014
Serum level of testosterone, dihydrotestosterone and IGF-1 during an acute exacerbation of COPD and their relationships with inflammatory and prognostic indices: a pilot study. Minerva medica, 2014, Volume: 105, Issue:4 Topics: Aged; APACHE; Biomarkers; Dihydrotestosterone; Disease Progression; Female; Humans; Hypogonadism; Inflammation; Insulin-Like Growth Factor I; Male; Pilot Projects; Prognosis; Pulmonary Disease, Chronic Obstructive; Reference Values; Serum Amyloid A Protein; Testosterone	2014
Elevated YKL40 is associated with advanced prostate cancer (PCa) and positively regulates invasion and migration of PCa cells. Endocrine-related cancer, 2014, Volume: 21, Issue:5 Topics: Adipokines; Aged; Aged, 80 and over; Androgen Antagonists; Androgens; Benzamides; Cell Line; Cell Line, Tumor; Cell Movement; Chitinase-3-Like Protein 1; Dihydrotestosterone; Disease Progression; Humans; Lectins; Male; Metribolone; Middle Aged; Neoplasm Invasiveness; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms	2014
The UGT2B28 Sex-steroid Inactivation Pathway Is a Regulator of Steroidogenesis and Modifies the Risk of Prostate Cancer Progression. European urology, 2016, Volume: 69, Issue:4 Topics: Adult; Aged; Biomarkers, Tumor; Biopsy; Dihydrotestosterone; Disease Progression; Gas Chromatography-Mass Spectrometry; Genetic Predisposition to Disease; Glucuronides; Glucuronosyltransferase; Humans; Kallikreins; Linear Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Grading; Phenotype; Predictive Value of Tests; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Risk Factors; Tandem Mass Spectrometry; Testosterone	2016
[Regulatory effect of Skp2 on the expression and transactivation of the androgen receptor in the progression of castration-resistant prostate cancer]. Zhonghua nan ke xue = National journal of andrology, 2016, Volume: 22, Issue:2 Topics: Androgens; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; Gene Knockdown Techniques; Humans; Male; Neoplasm Proteins; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; S-Phase Kinase-Associated Proteins; Transcriptional Activation; Up-Regulation	2016
Anti-proliferation effects of Cistanches salsa on the progression of benign prostatic hyperplasia. Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:1 Topics: Animals; Apoptosis; Cell Proliferation; Cistanche; Cyclooxygenase 2; Dihydrotestosterone; Disease Progression; Male; Nitric Oxide Synthase Type II; Organ Size; Phytotherapy; Plant Extracts; Plants, Medicinal; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley	2016
Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures. Oncotarget, 2017, Feb-07, Volume: 8, Issue:6 Topics: Androgen Antagonists; Binding Sites; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Phosphorylation; Promoter Regions, Genetic; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; src-Family Kinases; Time Factors; Transcription, Genetic; Transcriptome; Transfection	2017
MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression. Hormones & cancer, 2017, Volume: 8, Issue:2 Topics: Androgen Antagonists; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dihydrotestosterone; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Receptors, Androgen; Triple Negative Breast Neoplasms	2017
Androgen regulation of the androgen receptor coregulators. BMC cancer, 2008, Aug-01, Volume: 8 Topics: Androgens; Animals; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; Gene Expression Regulation; Genetic Vectors; Humans; Male; Mice; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors	2008
Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer research, 2009, Apr-15, Volume: 69, Issue:8 Topics: Adenosine Triphosphatases; Cell Growth Processes; Cell Survival; Dihydrotestosterone; Disease Progression; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Male; Metribolone; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Transcription, Genetic	2009
Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene. Experimental cell research, 2010, May-15, Volume: 316, Issue:9 Topics: Androgen Antagonists; Androgens; Azacitidine; Blotting, Western; CpG Islands; Decitabine; Dihydrotestosterone; Disease Progression; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Receptor, IGF Type 1; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured	2010
Androgen regulates ADAMTS15 gene expression in prostate cancer cells. Cancer investigation, 2010, Volume: 28, Issue:7 Topics: ADAM Proteins; ADAMTS Proteins; ADAMTS1 Protein; Androgens; Animals; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Nude; Prostatic Neoplasms	2010
Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression. BMC cancer, 2010, Dec-06, Volume: 10 Topics: 3-Hydroxysteroid Dehydrogenases; Blotting, Western; Cell Line, Tumor; Cell Survival; Computational Biology; Dihydrotestosterone; Disease Progression; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Estradiol; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Hydroxyprostaglandin Dehydrogenases; Insulin-Like Growth Factor I; Male; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Calcitriol; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Tumor Suppressor Protein p53; Up-Regulation; Vascular Endothelial Growth Factor A	2010
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-16, Volume: 108, Issue:33 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Castration; Dihydrotestosterone; Disease Progression; Humans; Male; Membrane Proteins; Metabolic Networks and Pathways; Mice; Prostatic Neoplasms; Testosterone; Transplantation, Heterologous	2011
Dihydrotestosterone--a culprit in left ventricular hypertrophy. International journal of cardiology, 2012, Mar-22, Volume: 155, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Dihydrotestosterone; Disease Progression; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Risk Factors	2012
Dihydrotestosterone synthesis from adrenal precursors does not involve testosterone in castration-resistant prostate cancer. Cancer biology & therapy, 2012, Volume: 13, Issue:5 Topics: Dihydrotestosterone; Disease Progression; Humans; Male; Molecular Targeted Therapy; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Testosterone	2012
Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat. Journal of lipid research, 2013, Volume: 54, Issue:2 Topics: Acetyl-CoA Carboxylase; Aged; Androgens; Animals; Body Weight; Cell Line; Cholesterol; Diet, High-Fat; Dihydrotestosterone; Disease Progression; Down-Regulation; Estradiol; Estrogens; Fatty Acids; Fatty Liver; Humans; Hydroxymethylglutaryl CoA Reductases; Interleukin-1; Lipogenesis; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Orchiectomy; Organ Size; Oxidation-Reduction; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Testosterone; Tumor Necrosis Factor-alpha	2013
Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues. Andrology, 2013, Volume: 1, Issue:1 Topics: Aged; Androstenedione; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hypogonadism; Immunohistochemistry; Male; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone	2013
Expression of bone morphogenetic protein-7 (BMP-7) in human prostate. The Prostate, 2004, Apr-01, Volume: 59, Issue:1 Topics: Aged; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta	2004
Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells. International journal of cancer, 2004, Aug-20, Volume: 111, Issue:2 Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cyclooxygenase 2; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Disease Progression; Eicosanoic Acids; gamma-Linolenic Acid; Humans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Tumor Cells, Cultured	2004
Gonadal steroid regulation of renal injury in renal wrap hypertension. American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:3 Topics: Animals; Blood Pressure; Body Weight; Dihydrotestosterone; Disease Progression; Estradiol; Female; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Kidney Glomerulus; Male; Orchiectomy; Ovariectomy; Ovary; Proteinuria; Rats; Rats, Sprague-Dawley; Sex Characteristics; Steroids; Testis; Testosterone	2005
Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:7 Topics: Androgen Antagonists; Animals; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Disease Progression; eIF-2 Kinase; Female; Flutamide; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins B-raf; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Sex Factors; Signal Transduction; Testosterone Congeners	2005
The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population. European urology, 2005, Volume: 48, Issue:4 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Alanine; Alleles; Arginine; Biomarkers, Tumor; Case-Control Studies; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Luteinizing Hormone; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Risk Factors; Sex Hormone-Binding Globulin; Sweden; Terminal Repeat Sequences; Testosterone; Threonine; Valine	2005
Androgen regulation of prostasin gene expression is mediated by sterol-regulatory element-binding proteins and SLUG. The Prostate, 2006, Jun-15, Volume: 66, Issue:9 Topics: Androgens; Cell Line; Cell Line, Tumor; Dihydrotestosterone; Disease Progression; DNA, Complementary; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Snail Family Transcription Factors; Sterol Regulatory Element Binding Protein 2; Sterol Regulatory Element Binding Proteins; Transcription Factors; Transfection	2006
Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells. The Prostate, 2007, Feb-01, Volume: 67, Issue:2 Topics: Androgen Antagonists; Androgens; Cadmium; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Dihydrotestosterone; Disease Progression; Epithelial Cells; Estradiol; Estrogens; Flutamide; Gene Expression Regulation; Humans; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger; Signal Transduction	2007
The change in the dihydrotestosterone level in the prostate before and after androgen deprivation therapy in connection with prostate cancer aggressiveness using the Gleason score. The Journal of urology, 2007, Volume: 178, Issue:4 Pt 1 Topics: Aged; Aged, 80 and over; Androgen Antagonists; Biomarkers, Tumor; Dihydrotestosterone; Disease Progression; Flutamide; Goserelin; Humans; Leuprolide; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Orchiectomy; Prognosis; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone	2007
Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer. Cancer science, 2007, Volume: 98, Issue:11 Topics: ADAM Proteins; ADAM10 Protein; Aged; Aged, 80 and over; Amyloid Precursor Protein Secretases; Biopsy; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Dihydrotestosterone; Disease Progression; DNA Primers; Humans; Immunohistochemistry; Male; Membrane Proteins; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering	2007
5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression. Journal of cellular biochemistry, 2008, Aug-01, Volume: 104, Issue:5 Topics: Androstane-3,17-diol; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytoplasm; Dihydrotestosterone; Disease Progression; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Male; Models, Biological; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Time Factors	2008
Effects of dihydrotestosterone and estradiol on experimental IgA nephropathy induced by vomitoxin. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 26, Issue:1 Topics: Animals; Complement C3; Dihydrotestosterone; Disease Progression; Estradiol; Female; Glomerular Mesangium; Glomerulonephritis, IGA; Hematuria; Immunoglobulins; Kidney; Male; Mice; Orchiectomy; Ovariectomy; Sex Characteristics; Trichothecenes	1995
Estramustine-binding protein to dihydrotestosterone ratio in human prostatic carcinoma: a new marker for predicting disease progression. British journal of urology, 1996, Volume: 77, Issue:1 Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Carrier Proteins; Dihydrotestosterone; Disease Progression; Humans; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Secretory Proteins	1996
A polymorphism of the 5 alpha-reductase gene and its association with prostate cancer: a case-control analysis. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:3 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Aged; Aged, 80 and over; Alleles; Androgens; Black People; Case-Control Studies; Cohort Studies; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Frequency; Genotype; Homozygote; Humans; Incidence; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Prevalence; Prostate; Prostatic Neoplasms; Repetitive Sequences, Nucleic Acid; Risk Factors; Testosterone; White People	1997
Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression. Nature medicine, 1998, Volume: 4, Issue:1 Topics: Biomarkers, Tumor; Biopsy; Cell Division; Cell Nucleus; Dihydrotestosterone; Disease Progression; Gene Transfer Techniques; Humans; Kinetics; Male; Neoplasm Metastasis; Neprilysin; Polymerase Chain Reaction; Prostatic Neoplasms; Recombinant Proteins; Tetracycline; Time Factors; Transfection; Tumor Cells, Cultured	1998
Chronology and urodynamic characterization of micturition in neurohormonally induced experimental prostate growth in the rat. Neurourology and urodynamics, 1998, Volume: 17, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Chronic Disease; Dihydrotestosterone; Disease Models, Animal; Disease Progression; Drug Combinations; Follow-Up Studies; Male; Muscle Contraction; Organ Size; Prazosin; Prostate; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Ureter; Urinary Bladder Neck Obstruction; Urodynamics	1998
Elevated expression of FGF-2 does not cause prostate cancer progression in LNCaP cells. The Prostate, 1999, Jun-15, Volume: 40, Issue:1 Topics: Animals; Cell Division; Dihydrotestosterone; Disease Progression; Female; Fibroblast Growth Factor 2; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prostatic Neoplasms; Testosterone; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured	1999
Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression. Cancer research, 1999, Aug-01, Volume: 59, Issue:15 Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Androgens; Biomarkers; Bombesin; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Lineage; Chromogranin A; Chromogranins; Colforsin; Cyclic AMP; Cytoplasmic Granules; Dihydrotestosterone; Disease Progression; Epinephrine; Humans; Isoproterenol; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neoplastic Stem Cells; Neuroendocrine Tumors; Neurotensin; Parathyroid Hormone-Related Protein; Phenotype; Phosphopyruvate Hydratase; Prostatic Neoplasms; Protein-Tyrosine Kinases; Proteins; Second Messenger Systems; Serotonin; Tumor Cells, Cultured	1999
Tumor necrosis factor-alpha represses androgen sensitivity in the LNCaP prostate cancer cell line. The Journal of urology, 2000, Volume: 164, Issue:3 Pt 1 Topics: Antibiotics, Antineoplastic; Blotting, Northern; Blotting, Western; Carcinogens; Cell Division; Dactinomycin; Dihydrotestosterone; Disease Progression; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Luciferases; Male; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2000
Cytopathological changes in early stages of benign prostatic hyperplasia upon exposure to sustained delivery of androgens. Biomedical sciences instrumentation, 2002, Volume: 38 Topics: Androgens; Androstenediol; Animals; Dihydrotestosterone; Disease Progression; Male; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Testosterone	2002