dihydrotestosterone has been researched along with Breast Neoplasms in 251 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 113 (45.02) | 18.7374 |
| 1990's | 55 (21.91) | 18.2507 |
| 2000's | 39 (15.54) | 29.6817 |
| 2010's | 33 (13.15) | 24.3611 |
| 2020's | 11 (4.38) | 2.80 |
| Authors | Studies |
|---|---|
| An, Y; Beehler, BC; Fura, A; Golla, R; Grover, GJ; Hamann, LG; Huang, Y; Krystek, SR; Kuhns, JE; Lupisella, JA; Malley, MF; Ostrowski, J; Robl, JA; Sack, JS; Salvati, ME; Seethala, R; Sleph, PG; Sun, C; Wang, TC | 1 |
| Albert, JM; Gorityala, S; Montano, MM; Mozar, F; Sharma, V; Xu, Y | 1 |
| Abdullah, MS; Ahram, M; Alsafadi, DB; Battah, AH; Mustafa, SA | 1 |
| Brown, K; Michael, P; Roversi, G; Sharifi, N | 1 |
| Ebrahimie, E; Hanson, AR; Hickey, TE; Moore, NL; Tilley, WD | 1 |
| Liang, ZR; Ma, LM; Qu, LH | 1 |
| Alaniz, A; Andò, S; Beyer, AR; Coarfa, C; Du, L; Dustin, D; Edwards, DG; Fernandez, NM; Foulds, CE; Fuqua, SAW; Gao, M; Gelsomino, L; Gonzalez, T; Grimm, SL; Gu, G; Herzog, SK; Hilsenbeck, SG; Huang, HJ; Janku, F; Kim, JA; Kittler, R; Li, S; Liu, D; Lo, HC; Mills, GB; Rechoum, Y; Symmans, WF; Tian, L; Tsimelzon, A; Xu, J; Zhang, XH | 1 |
| Boers, J; Boersma, HH; de Vries, EFJ; Dorbritz, C; Glaudemans, AWJM; Hospers, GAP; Rikhof, B; Schröder, CP; Venema, CM | 1 |
| Abaza, H; Abdallah, S; Abdullah, MS; Ahram, M; Alsafadi, DB; Bawadi, R; Mustafa, E | 1 |
| Ahram, M; Al-Momany, B; Hammad, H | 1 |
| Kostecká, Z; Očenáš, P; Salayová, A; Valko-Rokytovská, M | 1 |
| Lin, SX; Poirier, D; Thériault, JF | 1 |
| Alonso-Diez, A; Caceres, S; de Andres, PJ; Illera, JC; Illera, MJ; Monsalve, B; Peña, L; Reuben, JM; Silvan, G; Woodward, WA | 1 |
| Chang, YC; Chen, CK; Chen, MJ; Chen, SN; Cheng, SP; Huang, WC; Lin, CH; Lin, JC; Liu, CL | 1 |
| Ishida, T; Miki, Y; Sasano, H; Suzuki, T; Takagi, K | 1 |
| Chan, YX; Yeap, BB | 1 |
| Ishida, T; Miki, Y; Onodera, Y; Sasano, H; Suzuki, T; Takagi, K; Watanabe, M | 1 |
| Abu Hammad, S; Ahram, M; Alhudhud, M; Bawadi, R; Khatib, F; Mustafa, E; Tahtamouni, L; Zihlif, M | 1 |
| Han, H; Lin, SX; Poirier, D; Sang, X | 1 |
| Chang, YC; Chen, SN; Cheng, SP; Lin, CH; Lin, JC; Liu, CL | 1 |
| Hammes, SR; Levin, ER | 1 |
| Han, H; Li, T; Lin, SX; Sang, X | 1 |
| Gohno, T; Hanamura, T; Hayashi, S; Ito, K; Kobayashi, Y; Konno, H; Kurosumi, M; Nishikawa, S; Niwa, T; Takei, H; Tazawa, C; Yamaguchi, Y | 1 |
| Inoue, S; Ishida, T; Ito, S; Miki, Y; Miyazaki, T; Sasano, H; Shibahara, Y; Suzuki, T; Takagi, K; Watanabe, M | 1 |
| Ebata, A; Hata, S; Hirakawa, H; Ishida, T; Masuda, M; McNamara, KM; Miki, Y; Nakano, K; Ohuchi, N; Sakurai, M; Sasano, H; Suzuki, T; Takagi, K | 1 |
| Altemus, J; Eng, C; He, X; Romigh, T; Wang, Y; Yu, Q | 1 |
| Iizuka, M; Ikaga, R; Kajitani, T; Okazaki, T; Okinaga, H; Susa, T; Tamamori-Adachi, M | 1 |
| Andrieu, T; Baker, ME; Bertolini, R; Frey, BM; Frey, FJ; Goepfert, C; Guettinger, A; Mani, O; Setoud, R; Uh, KY | 1 |
| Asthana, S; Mandal, CC; Mehta, J; Saxena, S | 1 |
| Doillon, CJ; Gérard, C; Lin, SX; Poirier, D; Thériault, JF; Wang, X | 1 |
| Lin, SX; Xu, D | 1 |
| Chang, TC; Changou, CA; Chin, YT; Davis, PJ; Fu, E; HuangFu, WC; Lai, HY; Lin, HY; Liu, LF; Yang, SH | 1 |
| Bentel, JM; Chua, VY; Harvey, J; Larma, I; Thomas, MA | 1 |
| Feng, J; Gao, H; Huang, B; Li, L; Li, X; Li, Y; Liu, D; Liu, J; Lu, J; Wang, G; Zhang, L; Zhang, N; Zhang, Y | 1 |
| Bianco-Miotto, T; Birrell, SN; Butler, LM; Clarke, CL; Cops, EJ; Moore, NL; Tilley, WD | 1 |
| Andò, S; Casaburi, I; Garofalo, C; Lanzino, M; Le Pera, M; McPhaul, MJ; Morelli, C; Sisci, D; Surmacz, E | 1 |
| Brettes, JP; Mathelin, C | 1 |
| Alder, J; Bitzer, J; Fink, N; Urech, C; Wight, E; Zanetti, R | 1 |
| Aboghe, DH; Bolduc, C; St-Amand, J; Yoshioka, M | 1 |
| Crews, CM; Cyrus, K; Deshaies, RJ; Kim, K; Rodriguez-Gonzalez, A; Sakamoto, KM; Salcius, M | 1 |
| Bucholtz, KM; Kacsoh, B; Mack, VL; Sun, J; Thomas, JL | 1 |
| Gotoh, Y; Kizu, R; Klinge, CM; Sanada, N; Shimazawa, R | 1 |
| Maia, C; Santos, C; Schmitt, F; Socorro, S | 1 |
| Blair, IA; Byrns, MC; Duan, L; Lee, SH; Penning, TM | 1 |
| Aka, JA; Chen, CQ; Lin, SX; Mazumdar, M; Poirier, D | 1 |
| Bucholtz, KM; Mack, VL; Sun, J; Terrell, JR; Thomas, JL | 1 |
| Andò, S; Capparelli, C; Casaburi, I; Catalano, S; Garofalo, C; Giordano, C; Giordano, F; Lanzino, M; Maggiolini, M; Morelli, C; Sisci, D | 1 |
| Hirakawa, H; Miki, Y; Moriya, T; Ohuchi, N; Sasano, H; Suzuki, T; Takagi, K | 1 |
| Dotan, N; Mahajna, J; Wasser, SP | 1 |
| Brower, V | 1 |
| Aubé, M; Ayotte, P; Larochelle, C | 1 |
| Shao, Z; Shi, P; Tong, X; Yang, Y; Zhang, Y | 1 |
| Bailey, ST; Brown, M; Chen, Y; Imai, Y; Lim, E; Liu, XS; Ni, M; Rimm, DL; Wimberly, H | 1 |
| Inoue, S; Ishida, T; Miki, Y; Nakamura, Y; Onodera, Y; Sasano, H; Suzuki, T; Takagi, K; Watanabe, M | 1 |
| Barker, S; Glover, HR; Malouitre, SD; Puddefoot, JR; Vinson, GP | 2 |
| Ali, AA; Bellido, T; Chen, JR; Ebert, R; Fu, Q; Han, L; Jilka, RL; Kousteni, S; Mancino, AT; Manolagas, SC; O'Brien, CA; Parfitt, AM; Plotkin, L; Powers, CC; Stewart, SA; Vertino, AM; Weinstein, RS; Wen, Y | 1 |
| Hewitt, LM; MacLean, DD; McMaster, ME; Munkittrick, KR; Oakes, KD; Portt, CB; Pryce, AC; Van Der Kraak, GJ | 1 |
| GELHORN, A; HERRMANN, JB; HOLLAND, J; MOSS, J; SMELIN, A | 1 |
| GELLHORN, A; HERRMANN, JB; HOLLAND, JF; MOSS, J; SMELIN, A | 1 |
| HUGGINS, C; MAINZER, K | 1 |
| ALBERT, A; BLACKBURN, CM | 1 |
| BLACKBURN, CM; CHILDS, DS | 1 |
| CHELI, C | 1 |
| BRIZIARELLI, G; ERCOLI, A | 1 |
| AZZOLINI, G | 1 |
| ABE, O; DORFMAN, RI; HERRANEN, A | 1 |
| KENNEDY, BJ | 1 |
| CUNINGHAM, M; MEYER, KK; RONGONE, EL; SEGALOFF, A; WEETH, JB | 1 |
| GORDON, J; HELFENSTEIN, JE; KING, RJ | 1 |
| ESCHER, GC; FOLEY, CJ; SANFILIPPO, LJ; VOLK, H | 1 |
| GOLDENBERG, IS | 1 |
| MAINOLDI, F; MONETTI, C | 1 |
| Evtimova, V; Kaul, S; Weidle, UH; Zeillinger, R | 1 |
| Chen, SJ; Christman, JK; Igawa, T; Johansson, SL; Lee, MS; Lin, FF; Lin, JS; Lin, MF; Van Bemmel, D | 1 |
| Morrow, D; Qin, C; Safe, S; Smith, R | 1 |
| Aspinall, SR; Davison, A; Lennard, TW; Shenton, BK; Stamp, S | 1 |
| Bobseine, K; Gray, LE; Wilson, VS | 1 |
| Allan, RK; Bentel, JM; Greeve, MA; Harvey, JM | 1 |
| Bai, C; Chen, F; Freedman, L; Gambone, C; Harada, S; Kasparcova, V; Knecht, K; Leu, C; Reszka, A; Rutledge, SJ; Scafonas, A; Schmidt, A; Vogel, R; Zhang, H | 1 |
| Lelle, I; Prifti, S; Rabe, T; Strowitzki, T | 1 |
| Andò, S; De Amicis, F; Lanzino, M; Marsico, S; McPhaul, MJ; Panno, ML | 1 |
| Hampton, T | 1 |
| Bai, C; Bettoun, DJ; Chen, O; Freedman, L; Gambone, C; Hodor, P; McElwee-Witmer, S; Rutledge, SJ; Scafonas, A; Schmidt, A; Vogel, R | 1 |
| Barndt, RJ; Dickson, RB; Johnson, MD; Kiyomiya, K; Lee, MS; Lin, CY; Tseng, IC; Zuo, H | 1 |
| Brodie, A; Guo, Z; Macedo, LF; Qiu, Y; Sabnis, GJ; Tilghman, SL | 1 |
| Diamandis, EP; Paliouras, M | 1 |
| Akahira, J; Hayashi, S; Hirakawa, H; Ishida, T; Miki, Y; Moriya, T; Sasano, H; Suzuki, T; Yamaguchi, Y | 1 |
| Barker, S; Puddefoot, JR; Vinson, GP | 1 |
| Hitosugi, T; Sasaki, K; Sato, M; Suzuki, Y; Umezawa, Y | 1 |
| Akahira, J; Evans, DB; Hirakawa, H; Ishida, T; Miki, Y; Moriya, T; Ono, K; Sasano, H; Shibuya, R; Suzuki, T; Yoshida, K | 1 |
| Arterburn, JB; Dai, D; Hathaway, HJ; Nayak, TK; Norenberg, JP; Prossnitz, ER; Ramesh, C; Sklar, LA | 1 |
| Azzam, DG; Bentel, JM; Greeve, MA; Harvey, JM; Tay, JW | 1 |
| Killinger, DW; Perel, E | 1 |
| Chalbos, D; Rochefort, H | 2 |
| Boffa, GA; Cutuli, B; Dine, G; Facchini, T; Lesaunier, F | 1 |
| Carlström, K; Döberl, A; Pousette, A; Rannevik, G; Wilking, N | 1 |
| Cavalie-Barthez, G; Chambon, M; Hallowes, R; Rochefort, H; Veith, F; Vignon, F | 1 |
| Leclercq, G | 1 |
| Bergink, EW; Turpijn, EW; van der Vies, J; van Meel, F | 1 |
| Murayama, Y | 1 |
| Hammond, GL; Kuhn, RW; Murai, JT; Nisker, JA; Raymoure, WJ; Siiteri, PK | 1 |
| D'Alessandro, L; De Giovanni, C; Galli, MC; Grassigli, A; Grilli, S; Nanni, P; Nicoletti, G; Paparopoli, G; Prodi, G; Tagariello, C | 1 |
| Bowen, M; Earnshaw, RJ; Levell, MJ | 1 |
| Eil, C | 1 |
| Beardwell, CG; Bu'Lock, D; Hindley, AC; Ribeiro, GG; Todd, ID; Wilkinson, PM | 1 |
| Hamada, Y; Matsui, K; Nomura, Y; Saeki, K; Tashiro, H | 1 |
| Aitken, SC; Lippman, ME | 1 |
| Hochberg, RB; Rosner, W | 1 |
| Chalbos, D; Keydar, I; Rochefort, H; Vignon, F | 1 |
| Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR | 1 |
| Forrest, AP; Hawkins, RA; Miller, WR | 1 |
| Etre, LA; MacIndoe, JH | 1 |
| Lee, FJ; MacIndoe, JH; Woods, GR | 1 |
| Eil, C; Lippman, ME; Loriaux, DL | 1 |
| Hellman, S; Little, JB; Nove, J; Piro, AJ; Weichselbaum, RR | 1 |
| Nash, AR; Ow, KT; Sarfaty, GA | 1 |
| Malaguti, C; Rossini, GP | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gatto, V; Leonardi, L | 1 |
| Calabrò, M; Carruba, G; Castagnetta, LA; Farruggio, R; Miceli, MD; Oliveri, G; Pfeffer, U; Sorci, CM | 1 |
| Blais, Y; Carrière, MC; Haagensen, DE; Labrie, F; Simard, J; Sugimoto, K | 1 |
| Bachelot, F; Barley, VL; Blackledge, GR; Dermaille, A; Fargeot, P; Namer, M; Pouillart, J; Rowland, CG; Tyrrell, CJ; Williams, CJ | 1 |
| el-Tanani, MK; Green, CD | 1 |
| Bentel, JM; Birrell, SN; Hickey, TE; Horsfall, DJ; Ricciardelli, C; Tilley, WD; Weger, MA | 1 |
| Mader, S; McCuaig, KA; White, JH | 1 |
| Cavalleri, A; Manzari, A; Martinetti, A; Recchione, C; Secreto, G; Venturelli, E | 1 |
| López-Boado, YS; López-Otín, C; Tolivia, J | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A | 1 |
| Birrell, SN; Hall, RE; Sutherland, RL; Tilley, WD | 1 |
| el Tanani, M; Green, C | 1 |
| Barley, VL; Blackledge, GR; Rowland, CG; Tyrrell, CJ; Williams, CJ | 1 |
| Filmer, A; Hackenberg, R; Hawighorst, T; Nia, AH; Schulz, KD | 1 |
| Couture, P; Labrie, F; Simard, J; Thériault, C | 1 |
| Brentani, MM; Escaleira, MT; Sonohara, S | 1 |
| Brentani, MM; Liberato, MH; Sonohara, S | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L | 1 |
| Balbín, M; López-Otín, C | 1 |
| Beck, S; Hackenberg, R; Hannig, K; Schmidt-Rhode, P; Scholz, A; Schulz, KD | 1 |
| Daxenbichler, G; Hofstädter, F; Marth, C; Müller-Holzner, E; Zeimet, AG | 1 |
| Blais, Y; Gingras, S; Haagensen, DE; Labrie, F; Simard, J | 1 |
| Bucci, A; Fariselli, G; Galante, E; Piromalli, D; Secreto, G; Venturelli, E | 1 |
| Darne, C; Fabre, S; Jean, C; Veyssière, G | 1 |
| Brown, TJ; Hochberg, RB; Hoyte, RM; Labaree, DC | 1 |
| Jimenez, J; Luizzi, MF; Sonnenschein, C; Soto, AM; Szelei, J | 1 |
| Blamey, RW; Hall, RE; Kelly, PA; Manning, DL; Nicholson, RI; Ormandy, CJ; Robertson, JF; Sutherland, RL | 1 |
| Fantl, V; Lee, CS; Ormandy, CJ; Ormandy, HF; Peters, G; Shine, J; Sutherland, RL | 1 |
| Fournier, A; Labrie, C; Lapointe, J; Richard, V | 1 |
| Labrie, C; Pouliot, F | 1 |
| Krueger, RG; Leedman, PJ; Yeap, BB | 1 |
| Hackenberg, R; Loos, S; Schulz, KD | 1 |
| Diamandis, EP; Jenkins, DJ; Rosenberg Zand, RS | 1 |
| Labrie, C; Lapointe, J | 1 |
| Leung, LK; Wang, TT | 1 |
| Andò, S; Donzé, O; Jeannin, E; Maggiolini, M; Picard, D | 1 |
| Heemers, H; Heyns, W; Swinnen, JV; Vanderhoydonc, F; Verhoeven, G | 1 |
| Klinga, K; Mayer, D; Morfin, R; Schmitt, M; Schnarr, B | 1 |
| Akahira, JI; Ariga, N; Darnel, AD; Kaneko, C; Moriya, T; Ogawa, S; Sasano, H; Suzuki, T; Takeyama, J | 1 |
| Bohlmann, MK; Ortmann, J; Prifti, S; Rabe, T; Rehberger-Schneider, S; Strowitzki, T | 1 |
| Carsol, JL; Gingras, S; Simard, J | 1 |
| Abul-Hajj, YJ | 2 |
| Becciolini, A; Calabresi, E; De Giuli, G; Giannotti, P; Lombardi, G; Serio, M | 1 |
| Deshpande, N; Hughes, D; Mitchell, I | 1 |
| Poortman, J; Prenen, JA; Schwarz, F; Thijssen, JH | 1 |
| Poortman, J; Schwarz, F; Thijssen, JH | 1 |
| Engel, B; Maass, H; Trams, G | 1 |
| Engelsman, E; Korsten, CB; Persijn, JP | 1 |
| Bolan, G; Huff, K; Lippman, ME | 1 |
| Engel, B; Maass, H; Nowakowski, H; Stolzenbach, G; Trams, G | 1 |
| Costlow, ME; Horwitz, KB; McGuire, WL | 1 |
| Perlin, E; Thompson, EB; Tormey, D | 1 |
| Jungblut, PW; Wagner, RK | 1 |
| Bruchovsky, N; Craven, S; Lesser, B; Van Doorn, E | 1 |
| Fishman, JH; Horn, H | 1 |
| Alford, TC; Do, HM; Geelhoed, GW; Lippman, ME; Tsangaris, NT | 1 |
| Horwitz, KB; Landrum, B; McGuire, WL; Zava, DT | 1 |
| Meyer, JS; Stevens, SC; Vandillen, N; White, WL | 1 |
| Hähnel, R; Twaddle, E | 1 |
| Bastert, G; Fortmeyer, HP; Gerner, R; Michel, RT; Nord, D; Schmidt-Matthiesen, H; Sturm, R | 1 |
| McGuire, WL; Zava, DT | 3 |
| Forrest, AP; Miller, WR; Shivas, AA | 1 |
| Frahm, H; Garbrecht, M; Pompecki, R; Schröder, G | 1 |
| Chamness, GC; Garola, RE; Horwitz, KB; McGuire, WL; Zava, DT | 1 |
| Maass, H; Trams, G | 1 |
| Berry, B; Carson, P; Deshpander, N; Mitchell, I | 1 |
| Lippman, ME; Monaco, ME | 1 |
| Huff, K; Lippman, M | 1 |
| Vitola, GIa; Zeĭkate, GA | 1 |
| Bolan, G; Huff, K; Lippman, M | 1 |
| Miller, LK; Sherman, MR | 1 |
| Dunning, MT; Pinkus, GS; Rose, LI; Underwood, RH; Williams, GH | 1 |
| Forrest, AP; Miller, WR | 2 |
| Alexander, IE; Clarke, CL; Hall, RE; Roman, SD; Sutherland, RL | 1 |
| Baroni, M; Borsellino, G; Buonaguidi, A; Elli, G; Mondina, R; Poma, S; Rescalli, S; Sonato, A | 1 |
| Dilley, WG; Haagensen, DE; Stewart, P; Wells, SA | 1 |
| Beato, M; Bock, K; Filmer, A; Hackenberg, R; Hawighorst, T; Schulz, KD; Slater, EP | 1 |
| de Launoit, Y; Haagensen, DE; Labrie, F; Simard, J | 1 |
| Clarke, CL; Kelly, PA; Ormandy, CJ; Sutherland, RL | 1 |
| Belanger, A; Dauvois, S; Labrie, F; Roy, R | 1 |
| Bernasconi, D; Cassulo, S; Fazzuoli, L; Giordano, G; Marugo, M; Miglietta, L; Ravera, F | 1 |
| Hackenberg, R; Hofmann, J; Hölzel, F; Kunzmann, R; Lüttchens, S; Schulz, KD | 1 |
| Rossini, GP | 1 |
| Chamness, GC; Salman, M | 1 |
| Dauvois, S; de Launoit, Y; Dufour, M; Labrie, F; Simard, J | 1 |
| Dauvois, S; Geng, CS; Labrie, F; Lévesque, C; Mérand, Y | 1 |
| Dauvois, S; Dumont, M; Hatton, AC; Labrie, C; Labrie, F; Mérand, Y; Poirier, D; Poulin, R; Simard, J; Zhao, HF | 1 |
| Hackenberg, R; Hofmann, J; Hölzel, F; Schulz, KD; Wolff, G | 1 |
| Everson, LK; Ingle, JN; Krook, JE; Long, HJ; Mailliard, JA; McCormack, GW; Schaid, DJ | 1 |
| Dauvois, S; Haagensen, DE; Labrie, F; Lévesque, C; Mérand, Y; Simard, J | 1 |
| Couët, J; Dauvois, S; Dumont, M; Hatton, AC; Labrie, C; Labrie, F; Petitclerc, L; Poulin, R; Simard, J; Zhao, HF | 1 |
| Berrino, F; Cavalleri, A; Di Pietro, S; Fariselli, G; Pisani, P; Recchione, C; Secreto, G; Toniolo, P; Totis, A | 1 |
| Chalbos, D; Chambon, M; Rochefort, H; Vial, HJ | 1 |
| Dufour, JM; Labrie, F; Levesque, C; Merand, Y; Poirier, D; Poulin, R | 1 |
| Boutteville, C; Lefèbvre, J; Revillion, F; Vandewalle, B | 1 |
| Dauvois, S; Dumont, M; Garcia, T; Labrie, F; Schachter, B; Simard, J | 1 |
| Buzdar, AU; Chu, PS; Hortobagyi, GN | 1 |
| Dauvois, S; Haagensen, DE; Hatton, AC; Labrie, C; Labrie, F; Simard, J; Zhao, HF | 1 |
| Coune, A; Devleeschouwer, N; Leclercq, G; Nijs, M; Paridaens, R; Tueni, E; Vermeulen, A | 1 |
| Assailly, J; Bader, CA; Brami, M; Dautigny, N; Monet, JD; Thomas, M; Ulmann, A | 1 |
| Bird, CE; Clark, AF; Masters, V; Sterns, EE | 1 |
| Ballerini, P; Fariselli, G; Recchione, C; Secreto, G; Zambetti, M | 1 |
| Hackenberg, R; Hofmann, J; Hölzel, F; Schulz, KD | 1 |
| Hölzel, F; Pahnke, VG; Simon, WE | 1 |
| Canellos, GP | 1 |
| Bradlow, HL; Fishman, J; Hershcopf, R; Martucci, C | 1 |
| Baker, D; Labrie, F; Poulin, R | 1 |
| Blankenstein, MA; Fentener van Vlissingen, JM; Oprins, AC | 1 |
| Capony, F; Garcia, M; Rochefort, H; Vignon, F | 1 |
| Chalbos, D; Haagensen, D; Parish, T; Rochefort, H | 1 |
| Murphy, LC; Myal, Y; Shiu, RP; Tsuyuki, D | 1 |
| Barley, V; Blackledge, G; Hutcheon, A; Kaye, S; Keen, C; Rowland, C; Smith, D; Tyrrell, C; Webster, DJ; Williams, CJ | 1 |
| Benz, C; Hollander, C; Miller, B | 1 |
| Chenu, C; Delmas, PD; Meunier, PJ; Saez, S; Valentin-Opran, A; Vicard, E | 1 |
| Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC | 1 |
| Griffiths, K; Maynard, PV; Mistry, P | 1 |
| Blackstein, ME; Daniilescu, D; Kharlip, L; Killinger, DW; Perel, E | 1 |
| Anderson, DC; Bardsley, A; Hammond, GL; Langley, MS; Sellwood, RA | 1 |
| Lippman, ME; Shapiro, E | 1 |
| Coombes, RC; Hunt, J; Muindi, J; Neville, AM; Perez, D; Powles, TJ; Ward, M | 1 |
| Beardwell, CG; Bu'lock, D; Hindley, AC; St John, J; Wilkinson, PM | 1 |
| Cameron, EH; Foreest, AP; Gleave, EN; Griffiths, K; Jones, D | 1 |
| Forrest, AP; Hamilton, T; Miller, W | 1 |
| Görlich, L; Jungblut, PW; Wagner, RK | 1 |
| Forrest, AP; Hamilton, T; Miller, WR | 1 |
| Karl, HJ; Raith, L; Wirtz, A | 1 |
| Honetz, N; Neumann, E; Wurm, B | 1 |
| Braunsberg, H; Carter, AE; Irvine, WT; James, VH | 1 |
13 review(s) available for dihydrotestosterone and Breast Neoplasms
| Article | Year |
|---|---|
Adrenal Steroids and Resistance to Hormonal Blockade of Prostate and Breast Cancer.
Topics: Androgens; Breast Neoplasms; Dihydrotestosterone; Estrogen Receptor alpha; Estrogens; Female; Humans; Male; Prostate; Prostatic Neoplasms; Steroids | 2023 |
Breast Cancer: Targeting of Steroid Hormones in Cancerogenesis and Diagnostics.
Topics: Androstenedione; Biomarkers, Tumor; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Metabolic Networks and Pathways; Metabolomics; Recurrence; Tandem Mass Spectrometry | 2021 |
The interplay of endocrine therapy, steroid pathways and therapeutic resistance: Importance of androgen in breast carcinoma.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Aromatase; Breast Neoplasms; Dihydrotestosterone; Disease Progression; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Mice, Nude; Neoplasm Recurrence, Local; Receptors, Androgen | 2018 |
Dihydrotestosterone and cancer risk.
Topics: Androgens; Animals; Breast Neoplasms; Colorectal Neoplasms; Dihydrotestosterone; Endometrial Neoplasms; Estrogens; Female; Humans; Lung Neoplasms; Male; Prostatic Neoplasms; Risk Factors | 2018 |
Impact of estrogens in males and androgens in females.
Topics: Androgens; Animals; Bone and Bones; Breast Neoplasms; Central Nervous System; Dihydrotestosterone; Disease Progression; Estradiol; Estrogens; Female; Genitalia; Humans; Male; Mice; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; Sex Factors; Testosterone | 2019 |
[Dual effects of androgens on mammary gland].
Topics: Age Factors; Androgen Antagonists; Androgens; Breast Neoplasms; Cell Proliferation; Dihydrotestosterone; Estradiol; Estrogens; Female; Humans; Mammary Glands, Human; Neoplasms, Hormone-Dependent; Polymorphism, Genetic; Receptors, Androgen; Receptors, Estrogen; Signal Transduction | 2008 |
Androgens in human breast carcinoma.
Topics: Androgens; Aromatase; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Receptors, Estrogen | 2010 |
Trilostane in advanced breast cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Hormone-Dependent; Postmenopause; Rats | 2006 |
The serum transport of steroid hormones.
Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Hormones; Humans; Hydrocortisone; Kinetics; Male; Menstruation; Obesity; Ovarian Neoplasms; Polycystic Ovary Syndrome; Reference Values; Sex Hormone-Binding Globulin; Steroids; Transcortin | 1982 |
Hormonal effects on cell proliferation in rat prostate.
Topics: Androgens; Animals; Breast Neoplasms; Castration; Cell Division; Cell Nucleus; Cyclic AMP; Cytoplasm; Dihydrotestosterone; DNA; Estrogens; Feedback; Female; Genes; Homeostasis; Humans; Male; Prostate; Rats; Receptors, Cell Surface; Testosterone | 1975 |
Plasma steroid transport in subjects with tumors of hormonal target organs: a review.
Topics: Breast Neoplasms; Dihydrotestosterone; Endometrial Neoplasms; Estradiol; Female; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Sex Hormone-Binding Globulin | 1992 |
16 alpha-hydroxylation of estradiol: a possible risk marker for breast cancer.
Topics: Age Factors; Animals; Breast; Breast Neoplasms; Dihydrotestosterone; Estradiol; Estriol; Female; Haplorhini; Humans; Hydroxylation; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pan troglodytes; Pregnenolone; Progesterone; Rats; Risk; Species Specificity; Steroid 16-alpha-Hydroxylase; Testosterone | 1986 |
The 52K estrogen-regulated protein secreted by breast cancer cells and its clinical potential.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Division; Cell Line; Cells, Cultured; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Estriol; Estrone; Female; Humans; Immunoenzyme Techniques; Molecular Weight; Neoplasm Proteins | 1986 |
4 trial(s) available for dihydrotestosterone and Breast Neoplasms
| Article | Year |
|---|---|
Serial [
Topics: Aged; Androgen Antagonists; Anilides; Breast Neoplasms; Dihydrotestosterone; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Neoplasm Metastasis; Nitriles; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiopharmaceuticals; Receptors, Androgen; Tosyl Compounds | 2021 |
Multicentre cross-over study of aminoglutethimide and trilostane in advanced postmenopausal breast cancer.
Topics: Administration, Oral; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cross-Over Studies; Dihydrotestosterone; Drug Administration Schedule; Female; Humans; Middle Aged; Postmenopause; Treatment Outcome | 1995 |
Multicentre cross over study of aminoglutethimide and trilostane in advanced postmenopausal breast cancer.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aged; Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dihydrotestosterone; Drug Resistance; Estrogen Antagonists; Female; Humans; Hydrocortisone; Lyases; Menopause; Middle Aged; Treatment Outcome | 1993 |
Trilostane with hydrocortisone in treatment of metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Dihydrotestosterone; Female; Humans; Hydrocortisone; Middle Aged; Nausea; Neoplasm Metastasis; Prospective Studies; Vomiting | 1989 |
234 other study(ies) available for dihydrotestosterone and Breast Neoplasms
| Article | Year |
|---|---|
Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffold.
Topics: Administration, Oral; Animals; Breast Neoplasms; Bridged-Ring Compounds; Cells, Cultured; Dihydrotestosterone; Humans; Hydantoins; Luciferases; Male; Mice; Muscle, Skeletal; Muscular Atrophy; Myoblasts; Rats; Receptors, Androgen; Transcriptional Activation | 2006 |
Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Down-Regulation; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation; Humans; Ligands; Male; MCF-7 Cells; Prostatic Neoplasms; Receptors, Androgen; RNA-Binding Proteins; RNA, Small Interfering; Transcription Factors | 2022 |
Androgen downregulates desmocollin-2 in association with induction of mesenchymal transition of breast MDA-MB-453 cancer cells.
Topics: Androgens; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Desmocollins; Dihydrotestosterone; Epithelial-Mesenchymal Transition; Female; Humans; Triple Negative Breast Neoplasms | 2021 |
Anti-proliferative transcriptional effects of medroxyprogesterone acetate in estrogen receptor positive breast cancer cells are predominantly mediated by the progesterone receptor.
Topics: Androgens; Breast Neoplasms; Cell Proliferation; Dexamethasone; Dihydrotestosterone; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Medroxyprogesterone Acetate; Progesterone; Receptors, Androgen; Receptors, Progesterone; Transcriptome; Tumor Cells, Cultured | 2020 |
Differential impacts of charcoal-stripped fetal bovine serum on c-Myc among distinct subtypes of breast cancer cell lines.
Topics: Animals; Breast Neoplasms; Cattle; Cell Line, Tumor; Charcoal; Dihydrotestosterone; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Serum; Transcription, Genetic; Up-Regulation | 2020 |
Hormonal modulation of ESR1 mutant metastasis.
Topics: Animals; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mutation; Neoplasm Metastasis; Receptors, Androgen; Tamoxifen; Xenograft Model Antitumor Assays | 2021 |
Involvement of β-catenin in Androgen-induced Mesenchymal Transition of Breast MDA-MB-453 Cancer Cells.
Topics: beta Catenin; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3 beta; Humans; Receptors, Androgen | 2021 |
Dihydrotestosterone Induces Chemo-Resistance of Triple-Negative Breast MDA-MB-231 Cancer Cells Towards Doxorubicin Independent of ABCG2 and miR-328-3p.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Doxorubicin; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Proteins; Triple Negative Breast Neoplasms | 2021 |
The multi-specific human 17 beta-hydroxysteroid dehydrogenase type 7: Non-competitive inhibitors can target different catalyses to facilitate breast cancer treatment.
Topics: 17-Hydroxysteroid Dehydrogenases; Allosteric Site; Androgens; Breast Neoplasms; Catalysis; Cholesterol; Dihydrotestosterone; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Kinetics; Ligands; Protein Binding; Regression Analysis | 2021 |
In vitro and in vivo effect of flutamide on steroid hormone secretion in canine and human inflammatory breast cancer cell lines.
Topics: Androstenedione; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Dog Diseases; Dogs; Estradiol; Estrone; Female; Flutamide; Gonadal Steroid Hormones; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pregnenolone; Progesterone; Testosterone | 2018 |
Expression of 3β-Hydroxysteroid Dehydrogenase Type 1 in Breast Cancer is Associated with Poor Prognosis Independent of Estrogen Receptor Status.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Movement; Cell Proliferation; Dihydrotestosterone; Female; Follow-Up Studies; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multienzyme Complexes; Progesterone Reductase; Prognosis; Receptors, Estrogen; RNA, Small Interfering; Steroid Isomerases; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
ARHGAP15 in Human Breast Carcinoma: A Potent Tumor Suppressor Regulated by Androgens.
Topics: Adult; Aged; Aged, 80 and over; Androgens; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Cell Movement; Cell Proliferation; Cytoplasm; Dihydrotestosterone; Female; GTPase-Activating Proteins; Humans; MCF-7 Cells; Middle Aged; RNA, Messenger; Up-Regulation | 2018 |
The cellular and molecular effects of the androgen receptor agonist, Cl-4AS-1, on breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Gene Expression; Humans | 2018 |
Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism.
Topics: Aromatase Inhibitors; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cyclin D1; Dihydrotestosterone; Drug Therapy, Combination; Estradiol; Estradiol Dehydrogenases; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Hormone-Dependent; Steryl-Sulfatase; Sulfonic Acids; Tumor Cells, Cultured | 2018 |
Inhibition of 3β-Hydroxysteroid Dehydrogenase Type 1 Suppresses Interleukin-6 in Breast Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dihydrotestosterone; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Interleukin-6; Multienzyme Complexes; Oligonucleotide Array Sequence Analysis; Paclitaxel; Progesterone Reductase; Recombinant Proteins; RNA, Small Interfering; Steroid Isomerases | 2019 |
Mutual regulations and breast cancer cell control by steroidogenic enzymes: Dual sex-hormone receptor modulation upon 17β-HSD7 inhibition.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; 17-Hydroxysteroid Dehydrogenases; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Female; Humans; Receptors, Androgen; Steryl-Sulfatase | 2019 |
Androgen metabolite-dependent growth of hormone receptor-positive breast cancer as a possible aromatase inhibitor-resistance mechanism.
Topics: Androgens; Androstane-3,17-diol; Aromatase Inhibitors; Breast Neoplasms; Dihydrotestosterone; Drug Resistance, Neoplasm; Female; Green Fluorescent Proteins; Humans; Letrozole; MCF-7 Cells; Multienzyme Complexes; Nitriles; Progesterone Reductase; Receptors, Androgen; Receptors, Estrogen; Response Elements; Signal Transduction; Steroid Isomerases; Testosterone; Triazoles | 2013 |
Amyloid precursor protein in human breast cancer: an androgen-induced gene associated with cell proliferation.
Topics: Adult; Aged; Aged, 80 and over; Amyloid beta-Protein Precursor; Androgens; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Proliferation; Dihydrotestosterone; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; MCF-7 Cells; Middle Aged; Prognosis; Receptors, Androgen | 2013 |
Identification of androgen-responsive microRNAs and androgen-related genes in breast cancer.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Androgens; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Case-Control Studies; Cell Proliferation; Dihydrotestosterone; Female; Follow-Up Studies; Gene Expression Profiling; Humans; Immunoenzyme Techniques; MicroRNAs; Middle Aged; Neoplasm Staging; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Prognosis; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured; Young Adult | 2013 |
Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dihydrotestosterone; Drug Synergism; Female; Humans; Imidazoles; MCF-7 Cells; Mice, Nude; PTEN Phosphohydrolase; Quinolines; Receptors, Androgen; Time Factors; Tumor Suppressor Proteins; Up-Regulation; Xenograft Model Antitumor Assays | 2014 |
Wild-type and specific mutant androgen receptor mediates transcription via 17β-estradiol in sex hormone-sensitive cancer cells.
Topics: Active Transport, Cell Nucleus; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mutation; Parathyroid Hormone-Related Protein; Promegestone; Prostatic Neoplasms; Receptors, Androgen | 2015 |
Detection and functional portrayal of a novel class of dihydrotestosterone derived selective progesterone receptor modulators (SPRM).
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line; Cell Line, Tumor; Dihydrotestosterone; Female; Humans; Models, Molecular; Protein Binding; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Progesterone; Transcription, Genetic | 2015 |
A molecular analysis provides novel insights into androgen receptor signalling in breast cancer.
Topics: Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Dihydrotestosterone; Female; Humans; Neoplasm Proteins; Nuclear Proteins; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2015 |
Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cholesterol; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dihydrotestosterone; Estradiol; Estradiol Dehydrogenases; Estrogens; Estrone; Female; G1 Phase; Humans; MCF-7 Cells; Membrane Proteins; Mitochondrial Proteins; Multifunctional Enzymes; Proto-Oncogene Proteins c-bcl-2; Resting Phase, Cell Cycle | 2015 |
Mimicking postmenopausal steroid metabolism in breast cancer cell culture: Differences in response to DHEA or other steroids as hormone sources.
Topics: 17-Hydroxysteroid Dehydrogenases; Apoptosis; Breast; Breast Neoplasms; Cell Cycle; Cell Proliferation; Dehydroepiandrosterone; Dihydrotestosterone; Estrone; Female; Humans; MCF-7 Cells; Postmenopause | 2016 |
Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Drug Interactions; Estrogen Receptor alpha; Female; Humans; Integrin alphaVbeta3; MCF-7 Cells; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Activity of ABCG2 Is Regulated by Its Expression and Localization in DHT and Cyclopamine-Treated Breast Cancer Cells.
Topics: Androgens; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Cell Membrane; Cell Proliferation; Dihydrotestosterone; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplastic Stem Cells; Tumor Cells, Cultured; Veratrum Alkaloids | 2016 |
Androgen and AR contribute to breast cancer development and metastasis: an insight of mechanisms.
Topics: Androgens; Animals; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Gene Knockdown Techniques; Histone Demethylases; Humans; Mice; Neoplasm Metastasis; Prognosis; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Vimentin; Xenograft Model Antitumor Assays | 2017 |
Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors.
Topics: Androgens; Breast Neoplasms; Cell Proliferation; Dihydrotestosterone; Drug Evaluation, Preclinical; Estradiol; Humans; Medroxyprogesterone Acetate; Nandrolone; Progestins; Receptors, Androgen; Receptors, Progesterone; Testosterone Congeners; Tumor Cells, Cultured | 2008 |
Insulin receptor substrate 1 modulates the transcriptional activity and the stability of androgen receptor in breast cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoprecipitation; Insulin Receptor Substrate Proteins; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription, Genetic | 2009 |
Sexual dysfunction after premenopausal stage I and II breast cancer: do androgens play a role?
Topics: Adult; Androgens; Androsterone; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dihydrotestosterone; Estradiol; Female; Humans; Libido; Middle Aged; Orgasm; Premenopause; Sexual Dysfunction, Physiological; Testosterone | 2008 |
Effects of dihydrotestosterone on gene expression in mammary gland.
Topics: Animals; Breast Neoplasms; Dihydrotestosterone; Female; Gene Expression; Gene Expression Profiling; Humans; Male; Mammary Glands, Animal; Mice; Mice, Inbred C57BL; Orchiectomy; Ovariectomy; Transcription, Genetic | 2008 |
Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Drug Delivery Systems; Estradiol; Estrogen Receptor alpha; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Receptors, Androgen; Receptors, Steroid; Recombinant Fusion Proteins; Ubiquitination | 2008 |
Structural basis for the selective inhibition of human 3beta-hydroxysteroid dehydrogenase 1 in human breast tumor MCF-7 cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Arginine; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coenzymes; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mutant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity | 2009 |
Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells.
Topics: Androgens; Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Dihydrotestosterone; Female; Gene Expression Regulation; Humans; Immunoprecipitation; Luciferases; Male; Methylcholanthrene; Polymerase Chain Reaction; Prostatic Neoplasms; Repressor Proteins; RNA, Messenger; Transcription, Genetic | 2009 |
Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones.
Topics: Breast Neoplasms; Calcium-Binding Proteins; Cell Line, Tumor; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Female; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Intracellular Signaling Peptides and Proteins; Male; Prostatic Neoplasms | 2009 |
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer.
Topics: 20-alpha-Dihydroprogesterone; 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Aldo-Keto Reductase Family 1 Member C3; Androstenedione; Androsterone; Biocatalysis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dinoprost; Estradiol; Estrone; Etiocholanolone; Female; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hydroxyprostaglandin Dehydrogenases; Ketosteroids; Kinetics; Progesterone; Prostaglandin D2; Prostaglandins; Recombinant Proteins; Testosterone; Transfection; Up-Regulation | 2010 |
17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.
Topics: Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Estradiol; Estradiol Dehydrogenases; Gas Chromatography-Mass Spectrometry; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering | 2010 |
The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis.
Topics: 3-Hydroxysteroid Dehydrogenases; Amino Acids; Binding Sites; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Substrate Specificity | 2010 |
Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element.
Topics: Androgens; Binding Sites; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; DAX-1 Orphan Nuclear Receptor; Dihydrotestosterone; Female; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Receptors, Androgen; Response Elements | 2010 |
The culinary-medicinal mushroom Coprinus comatus as a natural antiandrogenic modulator.
Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Androgens; Aniline Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coprinus; Dexamethasone; Dihydrotestosterone; Down-Regulation; Female; Flutamide; Gene Expression; Genes, Reporter; Humans; Inhibitory Concentration 50; Luciferases; Male; Mifepristone; Nitriles; Plant Extracts; Prostate-Specific Antigen; Prostatic Neoplasms; Quinolines; Receptors, Androgen; Receptors, Glucocorticoid; Tumor Stem Cell Assay; Up-Regulation | 2011 |
Beyond FDG: Many Molecular Imaging Agents Are in Development.
Topics: Biomarkers, Tumor; Breast Neoplasms; Dihydrotestosterone; Drug Design; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Male; Neoplasms; Nuclear Medicine; Positron-Emission Tomography; Prostatic Neoplasms; Radiology; Radiopharmaceuticals; Receptor, ErbB-2; Receptors, Androgen; Sensitivity and Specificity; Tomography, X-Ray Computed | 2011 |
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
Topics: Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Humans; Hydrocarbons, Chlorinated; Neoplasms, Hormone-Dependent; Receptors, Androgen; Regression Analysis | 2011 |
Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer.
Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Ovarian Neoplasms; Phosphorylation; Receptors, Androgen; Receptors, Estrogen; S-Phase Kinase-Associated Proteins; Signal Transduction; Testosterone; Ubiquitin | 2011 |
Targeting androgen receptor in estrogen receptor-negative breast cancer.
Topics: Androgens; Anilides; Animals; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 3-alpha; Humans; Mice; Nitriles; Receptor, ErbB-2; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Tosyl Compounds; Transcriptional Activation; Up-Regulation; Wnt Proteins; Xenograft Model Antitumor Assays | 2011 |
Krüppel-like factor 5 in human breast carcinoma: a potent prognostic factor induced by androgens.
Topics: Adult; Aged; Aged, 80 and over; Androgens; Breast Neoplasms; Cell Proliferation; Dihydrotestosterone; Female; Humans; Kruppel-Like Transcription Factors; MCF-7 Cells; Middle Aged; Prognosis; RNA, Small Interfering | 2012 |
Non-competitive steroid inhibition of oestrogen receptor functions.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Dihydrotestosterone; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Protein Isoforms; Rats; Rats, Wistar; Receptors, Estrogen; Response Elements; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Reversal of bone loss in mice by nongenotropic signaling of sex steroids.
Topics: Animals; Apoptosis; Body Weight; Bone and Bones; Bone Density; Breast Neoplasms; Cell Division; Cells, Cultured; Compressive Strength; Dihydrotestosterone; Estradiol; Estrenes; Female; Humans; Male; Mice; Orchiectomy; Organ Size; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; Pyrazoles; Receptors, Estrogen; Seminal Vesicles; Transcription, Genetic; Tumor Cells, Cultured; Uterus | 2002 |
Oxidative stress and bioindicators of reproductive function in pulp and paper mill effluent exposed white sucker.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Line; Dexamethasone; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Female; Glucocorticoids; Humans; Insecticides; Linuron; Luciferases; Oxidative Stress; Plasmids; Promoter Regions, Genetic; Receptors, Glucocorticoid; Sunscreening Agents; Testosterone Congeners; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Ultraviolet Rays | 2003 |
An evaluation of stanolone in treatment of advanced mammary cancer.
Topics: Androgens; Breast; Breast Neoplasms; Dihydrotestosterone; Humans; Neoplasms | 1954 |
An evaluation of stanolone in treatment of advanced mammary cancer.
Topics: Androgens; Breast; Breast Neoplasms; Dihydrotestosterone; Humans; Neoplasms | 1955 |
Hormonal influences on mammary tumors of the rat. II. Retardation of growth of a transplanted fibroadenoma in intact female rats by steroids in the androstane series.
Topics: Androgens; Animals; Breast Neoplasms; Dihydrotestosterone; Estrogens; Female; Fibroadenoma; Humans; Mammary Neoplasms, Animal; Neoplasms, Experimental; Rats | 1957 |
Effects of 2-methyl-dihydrotestosterone and of testosterone on human pituitary gonadotropin.
Topics: Breast; Breast Neoplasms; Dihydrotestosterone; Gonadotropins; Gonadotropins, Pituitary; Humans; Pituitary Gland; Testosterone | 1959 |
Use of 2 alpha-methyl androstan-17 beta-ol, 3-one (2-methyl dihydrotestosterone) in the treatment of advanced cancer of the breast.
Topics: Androstanols; Breast; Breast Neoplasms; Dihydrotestosterone; Humans; Testosterone | 1959 |
[Clinical experiences in the treatment of metastases from breast carcinoma with an enolic derivative of dihydrotestosterone].
Topics: Breast Neoplasms; Dihydrotestosterone; Humans; Testosterone | 1962 |
Effect of enol-ether derivatives of dihydrotestosterone on 3-methylcholanthrene-induced rat mammary carcinoma.
Topics: Animals; Breast; Breast Neoplasms; Dihydrotestosterone; Ether; Ethers; Humans; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Testosterone | 1961 |
[Clinical experience in the treatment of carcinoma of the breast in aged subjects with a nonvirilizing enolic derivative of dihydrotestosterone].
Topics: Anatomy; Breast; Breast Neoplasms; Carcinoma; Carcinoma, Ductal; Dihydrotestosterone; Geriatrics; Humans | 1962 |
Influence of 2alpha-methyl-17beta-hydroxy-5alpha-androstan-3-one on incorporation of glycine-2-C14 into proteins of a rat mammary fibroadenoma. A possible bioassay method.
Topics: Animals; Biological Assay; Breast; Breast Neoplasms; Dihydrotestosterone; Fibroadenoma; Glycine; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasm Proteins; Proteins; Rats; Steroids | 1962 |
Stimulation of erythropoiesis by androgenic hormones.
Topics: Androgens; Anemia; Breast Neoplasms; Dihydrotestosterone; Erythropoiesis; Fluoxymesterone; Hematopoiesis; Humans; Methyltestosterone; Testosterone | 1962 |
HORMONAL THERAPY IN CANCER OF THE BREAST. XXII. EFFECT OF 17ALPHA-METHYL-5BETA-DIHYDROTESTOSTERONE ON CLINICAL COURSE AND HORMONAL EXCRETION.
Topics: 17-Ketosteroids; Androgens; Breast; Breast Neoplasms; Creatine; Creatinine; Desoxycorticosterone; Dihydrotestosterone; Gonadotropins; Humans; Luteinizing Hormone; Lymphatic Metastasis; Neoplasms; Pregnanediol; Prolactin; Urine | 1963 |
THE METABOLISM OF TESTOSTERONE BY TISSUE FROM NORMAL AND NEOPLASTIC RAT BREAST.
Topics: Adenocarcinoma; Adenofibroma; Androgens; Animals; Benz(a)Anthracenes; Breast Neoplasms; Carbon Isotopes; Carcinogens; Chromatography; Dihydrotestosterone; Estradiol; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metabolism; Neoplasms, Experimental; Oxidoreductases; Pharmacology; Progesterone; Rats; Research; Testosterone | 1964 |
HORMONAL THERAPY IN ADVANCED BREAST CANCER. 3. EFFECT OF 6-BETA-DIBROMOMETHYLENE TESTOSTERONE PROPIONATE COMPARED WITH THAT OF 2-ALPHA-METHYL DIHYDROTESTOSTERONE PROPIONATE ON CLINICAL COURSE AND METABOLISM OF SELECTED SERUM ELECTROLYTES.
Topics: Alkaline Phosphatase; Androgens; Blood Chemical Analysis; Blood Proteins; Breast; Breast Neoplasms; Calcium; Dihydrotestosterone; Electrolytes; Erythropoiesis; Humans; Metabolism; Neoplasms; Phosphorus; Testosterone; Testosterone Propionate | 1964 |
HORMONAL THERAPY OF WOMEN FOR METASTATIC BREAST CARCINOMA. VI. 17-BETA-HYDROXY-17-METHYL-2-OXA-5-ALPHA-ANDROSTAN-3-ONE (NSC-67068).
Topics: Anabolic Agents; Breast Neoplasms; Dihydrotestosterone; Gastrointestinal Diseases; Humans; Neoplasms; Oxytocin; Steroids; Toxicology | 1965 |
[The n-octylenolic ether of dihydrotestosterone associated with x-ray therapy in the treatment of advanced breast carcinoma].
Topics: Breast; Breast Neoplasms; Dihydrotestosterone; Ether; Ethers; Humans; Testosterone; X-Ray Therapy | 1961 |
Identification of CRASH, a gene deregulated in gynecological tumors.
Topics: Amino Acid Sequence; Asparaginase; Autoantigens; Base Sequence; Blotting, Northern; Breast Neoplasms; Cell Line, Tumor; Cloning, Molecular; Dihydrotestosterone; DNA, Complementary; Estradiol; Exons; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes; Genital Neoplasms, Female; HeLa Cells; HL-60 Cells; Humans; Immunohistochemistry; Introns; K562 Cells; Molecular Sequence Data; Norgestrel; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2004 |
p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Breast Neoplasms; Cell Division; Dihydrotestosterone; Estrogens; Humans; Male; Neoplasms, Hormone-Dependent; Phosphorylation; Prostate; Prostatic Neoplasms; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Testicular Neoplasms; Tumor Cells, Cultured; Up-Regulation | 2004 |
Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation.
Topics: Benzofurans; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Dihydrotestosterone; Estradiol; Female; Genes, Reporter; Humans; Male; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Receptors, Aryl Hydrocarbon; Time Factors; Transcriptional Activation | 2004 |
The proliferative effects of 5-androstene-3 beta,17 beta-diol and 5 alpha-dihydrotestosterone on cell cycle analysis and cell proliferation in MCF7, T47D and MDAMB231 breast cancer cell lines.
Topics: Anabolic Agents; Androgens; Androstenediol; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Dihydrotestosterone; Female; Humans; Time Factors | 2004 |
Development and characterization of a cell line that stably expresses an estrogen-responsive luciferase reporter for the detection of estrogen receptor agonist and antagonists.
Topics: Breast Neoplasms; Cell Line; Cloning, Molecular; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Estrogens, Non-Steroidal; Female; Fulvestrant; Genes, Reporter; Humans; Ligands; Light; Luciferases; Luminescent Measurements; Plasmids; Receptors, Estrogen; TATA Box; Transfection | 2004 |
Inhibition of MCF-7 breast cancer cell proliferation by 5alpha-dihydrotestosterone; a role for p21(Cip1/Waf1).
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Dihydrotestosterone; Female; Humans; Phosphorylation; Proto-Oncogene Proteins; Receptors, Androgen; Retinoblastoma Protein; Tumor Suppressor Proteins | 2004 |
Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol.
Topics: Adaptor Proteins, Signal Transducing; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Androstenediol; Androstenedione; Anilides; Animals; Breast Neoplasms; Carrier Proteins; Cell Division; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Dihydrotestosterone; Humans; Ligands; Macaca mulatta; Male; Mammary Tumor Virus, Mouse; Mice; Nerve Tissue Proteins; Nitriles; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, AMPA; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured | 2004 |
Induction of androgen receptor activity by norgestimate and norelgestromin in MDA-MB 231 breast cancer cells.
Topics: 17-alpha-Hydroxyprogesterone; Breast Neoplasms; Contraceptives, Oral, Combined; Dihydrotestosterone; Drug Combinations; Ethisterone; Genetic Vectors; Humans; Luciferases; Norgestrel; Oximes; Receptors, Androgen; Testosterone; Transfection; Tumor Cells, Cultured | 2004 |
Endogenous coactivator ARA70 interacts with estrogen receptor alpha (ERalpha) and modulates the functional ERalpha/androgen receptor interplay in MCF-7 cells.
Topics: Blotting, Western; Breast Neoplasms; Dihydrotestosterone; DNA; Estrogen Receptor alpha; Gene Expression; HeLa Cells; Humans; Immunosorbent Techniques; Nuclear Receptor Coactivators; Oncogene Proteins; Promoter Regions, Genetic; Receptor Cross-Talk; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2005 |
Clinical trials point to complexities of chemoprevention for cancer.
Topics: Aspirin; Breast Neoplasms; Clinical Trials as Topic; Diet; Dihydrotestosterone; Female; Finasteride; Humans; Male; Neoplasms; Prostatic Neoplasms; Selective Estrogen Receptor Modulators; Tamoxifen; Vitamin E | 2005 |
Interaction between the androgen receptor and RNase L mediates a cross-talk between the interferon and androgen signaling pathways.
Topics: Androgens; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dihydrotestosterone; Endoribonucleases; Enzyme Activation; Female; Gene Expression; Genes, Reporter; Humans; Interferon-gamma; Interferons; Ligands; Male; Models, Biological; Mutation; Prostatic Neoplasms; Receptor Cross-Talk; Receptors, Androgen; Recombinant Proteins; Signal Transduction | 2005 |
Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells.
Topics: Breast Neoplasms; Dihydrotestosterone; Enzyme Activation; Enzyme Induction; Estradiol; Female; Humans; Hydrolysis; Male; Membrane Glycoproteins; Prostatic Neoplasms; Proteinase Inhibitory Proteins, Secretory; Serine Endopeptidases; Tumor Cells, Cultured | 2006 |
Comparison of effects of 4-hydroxy tamoxifen and trilostane on oestrogen-regulated gene expression in MCF-7 cells: up-regulation of oestrogen receptor beta.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Estrogen Antagonists; Estrogen Receptor beta; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Tamoxifen; Up-Regulation | 2006 |
Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole.
Topics: Androgen Receptor Antagonists; Androgens; Androstenedione; Aromatase; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; RNA, Small Interfering; Transfection; Triazoles | 2006 |
Coordinated steroid hormone-dependent and independent expression of multiple kallikreins in breast cancer cell lines.
Topics: Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Female; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Kallikreins; Prostate-Specific Antigen | 2007 |
5Alpha-reductase type 1 and aromatase in breast carcinoma as regulators of in situ androgen production.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Aged; Aged, 80 and over; Androgens; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Chromatography, Liquid; Coculture Techniques; Dihydrotestosterone; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Receptors, Androgen; Tandem Mass Spectrometry; Tumor Cells, Cultured | 2007 |
Epidermal growth factor directs sex-specific steroid signaling through Src activation.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cytoplasm; Dihydrotestosterone; Endocytosis; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Estrogens; Female; Intracellular Membranes; Mice; Multiprotein Complexes; Receptors, Androgen; Receptors, Estrogen; Sex Characteristics; Signal Transduction; src-Family Kinases | 2007 |
Intratumoral concentration of sex steroids and expression of sex steroid-producing enzymes in ductal carcinoma in situ of human breast.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Aromatase; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Chromatography, Liquid; Dihydrotestosterone; Estradiol; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Electrospray Ionization; Steryl-Sulfatase; Stromal Cells; Survival Rate | 2008 |
Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Drug Delivery Systems; Drug Evaluation, Preclinical; Endometrial Neoplasms; Female; Humans; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Nandrolone; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Estrogen; Tissue Distribution | 2008 |
ERK/MAPK regulation of the androgen responsiveness of breast cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Receptors, Androgen | 2008 |
The metabolism of androstenedione and testosterone to C19 metabolites in normal breast, breast carcinoma and benign prostatic hypertrophy tissue.
Topics: Androstenedione; Androsterone; Breast; Breast Neoplasms; Dihydrotestosterone; Etiocholanolone; Female; Humans; Male; Prostatic Hyperplasia; Testosterone | 1983 |
Dual effects of the progestin R5020 on proteins released by the T47D human breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Mannose; Medroxyprogesterone; Medroxyprogesterone Acetate; Methionine; Norpregnadienes; Progesterone; Promegestone; Proteins; Receptors, Progesterone | 1984 |
[Polycythemia associated with breast cancer and bone metastases. Role of androgen therapy].
Topics: Bone Neoplasms; Breast Neoplasms; Carcinoma; Dihydrotestosterone; Female; Humans; Middle Aged; Polycythemia | 1984 |
Inhibition of steroid sulfatase activity by danazol.
Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma; Culture Techniques; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estrogen Antagonists; Estrone; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Pregnadienes; Tamoxifen | 1984 |
Effect of estradiol on nonmalignant human mammary cells in primary culture.
Topics: Adenofibroma; Breast; Breast Neoplasms; Cell Membrane; Cells, Cultured; Dexamethasone; Dihydrotestosterone; Epithelial Cells; Epithelium; Estradiol; Female; Humans; Membrane Proteins; Microscopy, Electron, Scanning; Microvilli; Molecular Weight; Progesterone; Tamoxifen | 1984 |
A 250-kilodalton cellular protein is induced by progestins in two human breast cancer cell lines MCF7 and T47D.
Topics: Breast Neoplasms; Cell Line; Chemical Phenomena; Chemistry; Dexamethasone; Dihydrotestosterone; Electrophoresis; Estradiol; Female; Humans; Molecular Weight; Neoplasm Proteins; Progestins; Promegestone | 1984 |
Routine assays for steroid hormone receptors.
Topics: Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estradiol; Estrenes; Female; Humans; Metribolone; Progestins; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Steroid; Tritium | 1984 |
Binding of progestagens to receptor proteins in MCF-7 cells.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Line; Cytosol; Dihydrotestosterone; Estradiol; Female; Humans; Kinetics; Myometrium; Progesterone; Rats; Receptors, Progesterone; Uterus | 1983 |
Plasma sex hormone-binding globulin (SHBG) and obesity in breast cancer patients.
Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Mastectomy; Neoplasms, Hormone-Dependent; Obesity; Risk; Sex Hormone-Binding Globulin | 1983 |
The simultaneous occurrence of cytoplasmic receptors for various steroid hormones in male breast carcinoma and gynaecomastia.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Dihydrotestosterone; Follicle Stimulating Hormone; Gynecomastia; Humans; Hydrocortisone; Luteinizing Hormone; Male; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid | 1980 |
Comparison of immunodiffusion and DHT-binding methods for the measurement of sex hormone binding globulin in plasma and serum.
Topics: Breast Neoplasms; Dihydrotestosterone; Female; Hirsutism; Humans; Immunodiffusion; Methods; Postpartum Period; Pregnancy; Sex Hormone-Binding Globulin | 1982 |
Familial incomplete male pseudohermaphroditism associated with impaired nuclear androgen retention. Studies in cultured skin fibroblasts.
Topics: Adolescent; Androgen-Insensitivity Syndrome; Breast Neoplasms; Cell Nucleus; Cells, Cultured; Centrifugation, Density Gradient; Cytosol; Dihydrotestosterone; Disorders of Sex Development; Fibroblasts; Humans; Male; Receptors, Androgen; Receptors, Steroid | 1983 |
Trilostane in the treatment of advanced breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis | 1983 |
[Evaluation of steroid hormone sensitivity of human breast cancer cells in culture (MCF-7) by a colony formation method].
Topics: Breast Neoplasms; Cells, Cultured; Colony-Forming Units Assay; Dihydrotestosterone; Estradiol; Female; Humans; Neoplasms, Hormone-Dependent; Progesterone | 1983 |
Hormonal regulation of de novo pyrimidine synthesis and utilization in human breast cancer cells in tissue culture.
Topics: Acetates; Breast Neoplasms; Culture Techniques; Dexamethasone; Dihydrotestosterone; DNA Replication; Estradiol; Fatty Acids; Humans; Progesterone; Pyrimidines; Tamoxifen | 1983 |
Interaction of 16 alpha-[125I]iodo-estradiol with estrogen receptor and other steroid-binding proteins.
Topics: Animals; Antibodies; Biological Assay; Breast Neoplasms; Cattle; Dihydrotestosterone; Estradiol; Female; Iodine Radioisotopes; Radioimmunoassay; Receptors, Estrogen; Sex Hormone-Binding Globulin; Uterus | 1980 |
Estrogens stimulate cell proliferation and induce secretory proteins in a human breast cancer cell line (T47D).
Topics: Breast Neoplasms; Cell Division; Cell Line; Dexamethasone; Dihydrotestosterone; DNA Replication; Estradiol; Estrogens; Female; Humans; Insulin; Progesterone; Promegestone; Protein Biosynthesis | 1982 |
Comparative studies of aromatase inhibitors in cultured human breast cancer cells.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone | 1982 |
Steroid metabolism and oestrogen receptors in human breast carcinomas.
Topics: Androstane-3,17-diol; Androstenedione; Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Menopause; Receptors, Estrogen; Testosterone | 1981 |
An antiestrogenic action of androgens in human breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Humans; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1981 |
The specific binding of androgens and the subsequent distribution of androgen-receptor complexes within MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Cytosol; Dihydrotestosterone; Female; Humans; Kinetics; Receptors, Androgen; Receptors, Steroid; Testosterone | 1981 |
A dispersed-whole cell method for the determination of androgen receptors in human skin fibroblasts.
Topics: Breast Neoplasms; Carcinoma; Cell Line; Cell Nucleus; Cells, Cultured; Cytosol; Dihydrotestosterone; Female; Fibroblasts; Humans; Kinetics; Male; Receptors, Androgen; Receptors, Steroid; Skin | 1980 |
Lack of selective killing by steroids in normal and malignant cells.
Topics: Breast Neoplasms; Cell Line; Cell Survival; Cortisone; Dexamethasone; Dihydrotestosterone; Estradiol; Fibroblasts; Hormones; Humans; Tamoxifen | 1980 |
The effects of steroids on phytohaemagglutin-induced lymphoblastogenesis.
Topics: Adult; Breast Neoplasms; Dihydrotestosterone; DNA Replication; Estradiol; Female; Fibrocystic Breast Disease; Hormones; Humans; Lymphocyte Activation; Lymphocytes; Male; Menstruation; Nandrolone; Phytohemagglutinins; Steroids | 1980 |
Steroid hormones and temperature induce changes of binding parameters of their receptors in intact cells.
Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Hydrocortisone; Kinetics; Ligands; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Temperature; Tumor Cells, Cultured | 1995 |
Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Flutamide; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tumor Cells, Cultured | 1995 |
Growth of LNCaP human prostate cancer cells is stimulated by estradiol via its own receptor.
Topics: Androgen Antagonists; Base Sequence; Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; Cytosol; Dihydrotestosterone; DNA Primers; DNA, Neoplasm; Estradiol; Female; Flutamide; Gene Expression; Humans; Kinetics; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostate-Specific Antigen; Prostatic Neoplasms; Radioligand Assay; Receptors, Estradiol; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Interleukin-6 inhibits the potent stimulatory action of androgens, glucocorticoids and interleukin-1 alpha on apolipoprotein D and GCDFP-15 expression in human breast cancer cells.
Topics: Androgens; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dexamethasone; Dihydrotestosterone; Drug Interactions; Estradiol; Estrogen Antagonists; Glucocorticoids; Glycoproteins; Humans; Interleukin-1; Interleukin-6; Kinetics; Membrane Transport Proteins; Neoplasm Proteins; Stimulation, Chemical; Tumor Cells, Cultured | 1995 |
Oestrogen-induced genes, pLIV-1 and pS2, respond divergently to other steroid hormones in MCF-7 cells.
Topics: Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression; Gene Expression Regulation, Neoplastic; Hormones; Humans; Polyunsaturated Alkamides; Progesterone; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Androgens induce divergent proliferative responses in human breast cancer cell lines.
Topics: Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Division; Dihydrotestosterone; Flutamide; Humans; Imidazoles; Imidazolidines; Nandrolone; Oligonucleotides, Antisense; Receptors, Androgen; Tumor Cells, Cultured | 1995 |
A simple and sensitive high-throughput assay for steroid agonists and antagonists.
Topics: Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Dexamethasone; Dihydrotestosterone; Gene Expression; Gene Transfer Techniques; Genes, Reporter; HeLa Cells; Herpesvirus 4, Human; Humans; Plasmids; Progesterone; Promoter Regions, Genetic; Steroids; Transfection; Tumor Cells, Cultured | 1994 |
Testosterone, dihydrotestosterone and oestradiol levels in postmenopausal breast cancer tissues.
Topics: Aged; Aged, 80 and over; Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Menopause; Middle Aged; Testosterone | 1995 |
Apolipoprotein D gene induction by retinoic acid is concomitant with growth arrest and cell differentiation in human breast cancer cells.
Topics: Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Cell Differentiation; Cell Division; Cell Nucleus; Cell-Free System; Cycloheximide; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Isomerism; Lactoferrin; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Tretinoin; Tumor Cells, Cultured | 1994 |
5-En-androstene-3 beta,17 beta-diol inhibits the growth of MCF-7 breast cancer cells when oestrogen receptors are blocked by oestradiol.
Topics: Androstenediol; Breast Neoplasms; Cell Division; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1994 |
MDA-MB-453, an androgen-responsive human breast carcinoma cell line with high level androgen receptor expression.
Topics: Blotting, Southern; Breast Neoplasms; Cell Division; Dihydrotestosterone; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Middle Aged; Nandrolone; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Testosterone Congeners; Tumor Cells, Cultured | 1994 |
Differential steroid responsiveness of two estrogen regulated genes in MCF-7 cells.
Topics: Blotting, Northern; Breast Neoplasms; Cell Line; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Progesterone; Receptors, Estrogen; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Medroxyprogesterone acetate inhibits the proliferation of estrogen- and progesterone-receptor negative MFM-223 human mammary cancer cells via the androgen receptor.
Topics: Androgen Receptor Antagonists; Breast Neoplasms; Cell Division; Dexamethasone; Dihydrotestosterone; Female; Humans; Medroxyprogesterone Acetate; Tumor Cells, Cultured | 1993 |
Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Flutamide; Humans; Kinetics; Medroxyprogesterone Acetate; Receptors, Androgen; Tumor Cells, Cultured | 1993 |
Sex steroids induced up-regulation of 1,25-(OH)2 vitamin D3 receptors in T 47D breast cancer cells.
Topics: Breast Neoplasms; Calcitriol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Androgen; Receptors, Calcitriol; Receptors, Estrogen; Receptors, Steroid; Tamoxifen; Tumor Cells, Cultured; Up-Regulation | 1993 |
Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dihydrotestosterone; Down-Regulation; Estradiol; Female; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Indirect growth inhibition of the MDA-MB-231 hormone-independent breast cancer cell line by dihydrotestosterone.
Topics: Breast Neoplasms; Cell Division; Dihydrotestosterone; Female; Humans; Neoplasms, Hormone-Dependent; Receptors, Androgen; Tumor Cells, Cultured | 1996 |
Hormonal regulation of the human pepsinogen C gene in breast cancer cells. Identification of a cis-acting element mediating its induction by androgens, glucocorticoids, and progesterone.
Topics: Base Sequence; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Dexamethasone; Dihydrotestosterone; DNA Primers; Estradiol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Pepsinogens; Polymerase Chain Reaction; Progesterone; Promoter Regions, Genetic; Receptors, Androgen; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic; Transfection | 1996 |
Androgen-like and anti-androgen-like effects of antiprogestins in human mammary cancer cells.
Topics: Androgen Antagonists; Antineoplastic Agents; Binding, Competitive; Breast Neoplasms; Cell Division; Dihydrotestosterone; Estrenes; Flutamide; Gonanes; Humans; Mifepristone; Models, Biological; Progestins; Receptors, Androgen; Transfection; Tumor Cells, Cultured | 1996 |
Effects of sex- and glucocorticoid steroids on breast cancer cells grown as either multicellular tumor spheroids or monolayers.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Spheroids, Cellular; Steroids; Tamoxifen; Tumor Cells, Cultured | 1996 |
Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression in human breast cancer cells.
Topics: Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Glycoproteins; Humans; Interleukin-13; Interleukin-4; Membrane Transport Proteins; Mitogens; Neoplasm Proteins; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Intratumour amount of sex steroids in elderly breast cancer patients. An approach to the biological characterization of mammary tumours in the elderly.
Topics: Age Factors; Aged; Breast Neoplasms; Carcinoma; Dihydrotestosterone; Estradiol; Female; Humans; Middle Aged; Radioimmunoassay; Testosterone | 1996 |
Protein kinase C pathway potentiates androgen-mediated gene expression of the mouse vas deferens specific aldose reductase-like protein (MVDP).
Topics: Aldehyde Reductase; Animals; Breast Neoplasms; Bucladesine; Carcinoma; Cell Line; Chlorocebus aethiops; Cyclic AMP-Dependent Protein Kinases; Dihydrotestosterone; Enzyme Activation; Gene Expression Regulation; Humans; Male; Mammary Tumor Virus, Mouse; Mice; Promoter Regions, Genetic; Protein Kinase C; Proteins; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Vas Deferens | 1996 |
7 alpha-iodine-125-iodo-5 alpha-dihydrotestosterone: a radiolabeled ligand for the androgen receptor.
Topics: Affinity Labels; Analysis of Variance; Animals; Binding Sites; Binding, Competitive; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Iodine Radioisotopes; Liver; Male; Muscle, Skeletal; Prostate; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Thyroid Gland; Tissue Distribution; Tumor Cells, Cultured | 1997 |
Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor.
Topics: Androgen Antagonists; Androgens; Anilides; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Metribolone; Nandrolone; Nitriles; Receptors, Androgen; Testosterone; Testosterone Congeners; Tosyl Compounds; Transfection; Tumor Cells, Cultured | 1997 |
Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in breast cancer.
Topics: Blotting, Northern; Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Progesterone; Prolactin; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Receptors, Steroid; Tumor Cells, Cultured | 1997 |
Amplification, expression, and steroid regulation of the preprogalanin gene in human breast cancer.
Topics: Blotting, Northern; Blotting, Southern; Breast Neoplasms; Chromosomes, Human, Pair 11; Dexamethasone; Dihydrotestosterone; DNA, Neoplasm; Estrogens; Galanin; Gene Amplification; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Progestins; Protein Precursors; RNA, Messenger; Steroids; Tumor Cells, Cultured | 1998 |
Androgens down-regulate bcl-2 protooncogene expression in ZR-75-1 human breast cancer cells.
Topics: Androgen Antagonists; Androgens; Breast Neoplasms; Caspase 3; Caspases; Dihydrotestosterone; Down-Regulation; Estradiol; Estrogens; Female; Flutamide; Humans; Immunohistochemistry; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1999 |
Expression profile of agonistic Smads in human breast cancer cells: absence of regulation by estrogens.
Topics: Breast Neoplasms; Dihydrotestosterone; DNA-Binding Proteins; Estrogens; Humans; Neoplasms, Hormone-Dependent; RNA, Messenger; Smad2 Protein; Smad3 Protein; Smad4 Protein; Trans-Activators; Transforming Growth Factor beta; Tumor Cells, Cultured | 1999 |
Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Dihydrotestosterone; Drug Stability; Female; Gene Expression Regulation; Homeostasis; Humans; Male; Prostatic Neoplasms; Protein Processing, Post-Translational; Receptors, Androgen; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
Regulation of GCDFP-15 expression in human mammary cancer cells.
Topics: Androgen Antagonists; Anilides; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Transport Proteins; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured | 1999 |
Development and evaluation of a competitive time-resolved immunofluorometric assay for the estrogen-regulated protein pS2.
Topics: Aldosterone; Amino Acid Sequence; Antibodies, Monoclonal; Binding, Competitive; Biotin; Breast Neoplasms; Calibration; Chemistry, Clinical; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Immunologic; Drosophila Proteins; Estradiol; Evaluation Studies as Topic; Fluorescent Antibody Technique; Fluorometry; Glucocorticoids; Integrin alpha Chains; Integrins; Molecular Sequence Data; Nandrolone; Norgestrel; Progesterone Congeners; Sensitivity and Specificity; Testosterone Congeners; Tumor Cells, Cultured | 1999 |
Identification and cloning of a novel androgen-responsive gene, uridine diphosphoglucose dehydrogenase, in human breast cancer cells.
Topics: Amino Acid Sequence; Androgens; Base Sequence; Breast Neoplasms; Cloning, Molecular; Dihydrotestosterone; Female; Humans; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Uridine Diphosphate Glucose Dehydrogenase | 1999 |
Paradoxical regulation of Bcl-2 family proteins by 17beta-oestradiol in human breast cancer cells MCF-7.
Topics: Adenocarcinoma; Apoptosis; bcl-X Protein; Breast Neoplasms; Cell Count; Dihydrotestosterone; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Tamoxifen | 1999 |
Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha.
Topics: Androgens; Androstenediol; Breast Neoplasms; Cell Division; Cloning, Molecular; Dehydroepiandrosterone; Dihydrotestosterone; Estrogen Receptor alpha; Female; Genes, Reporter; HeLa Cells; Humans; Luciferases; Receptors, Estrogen; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Testosterone; Transfection; Tumor Cells, Cultured; Uterus | 1999 |
Progestins and androgens increase expression of Spot 14 in T47-D breast tumor cells.
Topics: Breast Neoplasms; Chromosomes, Human, Pair 11; Dihydrotestosterone; Female; Gene Expression; Humans; Lipids; Metribolone; Neoplasms, Hormone-Dependent; Nuclear Proteins; Pregnenediones; Progesterone; Progesterone Congeners; Proteins; Testosterone Congeners; Transcription Factors; Tumor Cells, Cultured | 2000 |
Dehydroepiandrosterone stimulates proliferation and gene expression in MCF-7 cells after conversion to estradiol.
Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Chromatography, Thin Layer; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Immunoassay; Mitogens; Tamoxifen; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2001 |
5alpha-reductases in human breast carcinoma: possible modulator of in situ androgenic actions.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Dihydrotestosterone; Female; Humans; Immunohistochemistry; Isoenzymes; Middle Aged; Receptors, Androgen; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Testosterone and 5 alpha-dihydrotestosterone inhibit in vitro growth of human breast cancer cell lines.
Topics: Blotting, Western; Breast Neoplasms; Cell Division; Culture Media, Serum-Free; Dihydrotestosterone; Female; Humans; Immunohistochemistry; Kinetics; Receptors, Androgen; Testosterone; Tumor Cells, Cultured | 2002 |
Synergistic action of prolactin (PRL) and androgen on PRL-inducible protein gene expression in human breast cancer cells: a unique model for functional cooperation between signal transducer and activator of transcription-5 and androgen receptor.
Topics: 5' Flanking Region; Animals; Apolipoproteins; Apolipoproteins D; Base Sequence; Binding Sites; Breast Neoplasms; Carrier Proteins; Conserved Sequence; Dihydrotestosterone; DNA-Binding Proteins; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Transport Proteins; Milk Proteins; Molecular Sequence Data; Mutation; Prolactin; Promoter Regions, Genetic; Receptors, Androgen; Response Elements; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Steroid delta 4-5 beta-reductase in human mammary tumors.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Breast Neoplasms; Dihydrotestosterone; Etiocholanolone; Female; History, 18th Century; Humans; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stereoisomerism; Testosterone | 1979 |
Plasma estrogens and androgens in male breast cancer.
Topics: Adult; Aged; Androgens; Androstenedione; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estriol; Estrogens; Estrone; Follow-Up Studies; Humans; Male; Middle Aged; Radioimmunoassay; Testosterone | 1976 |
Effect of tamoxifen pre-treatment on the retention of tritiated oestradiol and 5alpha-dihydrotestosterone and on glucose metabolism in human breast carcinomas.
Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Glucose; Glucosephosphate Dehydrogenase; Glycerolphosphate Dehydrogenase; Humans; Phosphofructokinase-1; Tamoxifen | 1978 |
Interaction of delta-5-androstene-3beta, 17beta-diol with estradiol and dihydrotestosterone receptors in human myometrial and mammary cancer tissue.
Topics: Adult; Aged; Androstenediols; Androstenedione; Binding, Competitive; Breast Neoplasms; Cyproterone; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Humans; Middle Aged; Nafoxidine; Receptors, Cell Surface; Testosterone; Uterus | 1975 |
Androgens in postmenopausal breast cancer: excretion, production and interaction with estrogens.
Topics: 17-Ketosteroids; Aged; Androgens; Androstenedione; Binding, Competitive; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Myometrium; Receptors, Cell Surface; Testosterone | 1975 |
Steroid hormone receptors in human breast cancer and the clinical significance.
Topics: Breast Neoplasms; Castration; Cytoplasm; Dihydrotestosterone; Estradiol; Female; Humans; Hypophysectomy; Menopause; Neoplasm Metastasis; Receptors, Cell Surface | 1975 |
Oestrogen and androgen receptors in breast cancer and response to endocrine therapy.
Topics: Breast Neoplasms; Castration; Dihydrotestosterone; Estrogens; Female; Humans; Receptors, Cell Surface | 1975 |
Human breast cancer responsive to androgen in long term tissue culture.
Topics: Androgen Antagonists; Androgens; Binding Sites; Breast Neoplasms; Cell Division; Cell Line; Dihydrotestosterone; DNA, Neoplasm; Estrenes; Humans; Neoplasm Proteins; Protein Biosynthesis; Receptors, Cell Surface; Testosterone | 1975 |
Metabolism of dehydroepiandrosterone by hormone dependent and hormone independent human breast carcinoma.
Topics: Androstane-3,17-diol; Androstanes; Binding Sites; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Humans; In Vitro Techniques; Kinetics; Protein Binding; Receptors, Cell Surface; Testosterone | 1975 |
Steroid hormone receptors in human breast cancer and clinical correlations.
Topics: Adult; Aged; Breast Neoplasms; Castration; Dihydrotestosterone; Estradiol; Female; Humans; Menopause; Middle Aged; Nafoxidine; Receptors, Cell Surface; Remission, Spontaneous | 1975 |
MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors.
Topics: Binding Sites; Binding, Competitive; Breast Neoplasms; Cell Line; Cytosol; Dexamethasone; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Humans; Kinetics; Neoplasm Proteins; Progesterone; Protein Binding; Receptors, Cell Surface | 1975 |
Steroid-binding proteins in carcinoma of the human male breast.
Topics: Binding Sites; Breast Neoplasms; Dihydrotestosterone; Humans; Male; Middle Aged; Progesterone; Protein Binding; Receptors, Cell Surface; Testosterone | 1976 |
Oestradiol- and dihydrotestosterone receptors in normal and neoplastic human mammary tissue.
Topics: Adult; Breast; Breast Neoplasms; Carrier Proteins; Centrifugation, Density Gradient; Dihydrotestosterone; Electrophoresis, Agar Gel; Estradiol; Female; Humans; Middle Aged; Receptors, Cell Surface | 1976 |
Estimation of 5 alpha-dihydrotestosterone receptors in human breast tumors by the immobilized antibody method.
Topics: Aged; Antibodies; Binding, Competitive; Breast Neoplasms; Cytosol; Dihydrotestosterone; Estradiol; Humans; Immunologic Techniques; Middle Aged; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid | 1979 |
Steroid hormone receptors in human colon cancers.
Topics: Breast Neoplasms; Colonic Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasms, Hormone-Dependent; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Steroid | 1979 |
Androgen receptor assay with [3H]methyltrienolone (R1881) in the presence of progesterone receptors.
Topics: Binding, Competitive; Breast Neoplasms; Cell Line; Diethylstilbestrol; Dihydrotestosterone; Estrenes; Female; Humans; Kinetics; Progesterone; Receptors, Androgen; Receptors, Progesterone; Receptors, Steroid; Testosterone Congeners | 1979 |
Estrogen receptor assay of mammary carcinomas. Effects of testosterone-estradiol-binding globulin (TeBG) and serum estradiol-17 beta.
Topics: Adult; Breast Neoplasms; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Female; Hot Temperature; Humans; Receptors, Estrogen; Sex Hormone-Binding Globulin | 1979 |
Factors that may influence the estradiol receptor assay in human tissues:sex hormone binding globulin and endogenous steroids.
Topics: Breast Neoplasms; Charcoal; Cytosol; Dihydrotestosterone; Estradiol; Female; Humans; Receptors, Estrogen; Sex Hormone-Binding Globulin; Uterine Neoplasms | 1979 |
[Comparative gel-electrophoretic demonstration of steroid hormone receptors in human breast cancers and after their transplantation to athymic nude mice (proceedings)].
Topics: Animals; Breast Neoplasms; Dihydrotestosterone; Electrophoresis, Agar Gel; Estradiol; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid; Transplantation, Heterologous | 1977 |
Human breast cancer: androgen action mediated by estrogen receptor.
Topics: Androgens; Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Dihydrotestosterone; Humans; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Stimulation, Chemical; Translocation, Genetic | 1978 |
Factors affecting testosterone metabolism by human breast tissues.
Topics: Androstane-3,17-diol; Androstenedione; Breast; Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; In Vitro Techniques; Menopause; Testosterone | 1978 |
[Carcinoembryonic antigens (CEA) in patients with metastatic breast cancer under endocrine and therapeutic treatment (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoembryonic Antigen; Castration; Dihydrotestosterone; Ethinyl Estradiol; Female; Humans; Neoplasm Metastasis; Progesterone; Remission, Spontaneous; Tamoxifen | 1978 |
Receptors and breast cancer: do we know it all?
Topics: Breast Neoplasms; Cell Nucleus; Cells, Cultured; Cytosol; Dihydrotestosterone; Estradiol; Female; Humans; Nafoxidine; Progesterone; Receptors, Estrogen; Receptors, Progesterone | 1978 |
Androgen action through estrogen receptor in a human breast cancer cell line.
Topics: Androgens; Breast Neoplasms; Cell Line; Cytosol; Dihydrotestosterone; Estradiol; Female; Fluorides; Humans; Receptors, Estrogen | 1978 |
Specific binding of estradiol and dihydrotestosterone in human mammary cancers.
Topics: Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Menopause; Prognosis; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid | 1977 |
The accumulation of 5alpha-dihydrotesterone (5alpha-DHT) by human breast tissue.
Topics: Adipose Tissue; Adult; Aged; Breast; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Middle Aged; Organ Specificity | 1977 |
Estrogen receptor. Unoccupied sites in nuclei of a breast tumor cell line.
Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Cytosol; Dihydrotestosterone; Estradiol; Humans; Kinetics; Progesterone; Receptors, Estrogen; Receptors, Steroid | 1977 |
Insulin stimulation of fatty acid synthesis in human breast cancer in long term tissue culture.
Topics: Acetates; Breast Neoplasms; Cells, Cultured; Cycloheximide; Dactinomycin; Dihydrotestosterone; Estradiol; Female; Glucose; Humans; Insulin; Lipids | 1977 |
A demonstration of androgen and estrogen receptors in a human breast cancer using a new protamine sulfate assay.
Topics: Binding Sites; Binding, Competitive; Breast Neoplasms; Cytosol; Dihydrotestosterone; Estradiol; Female; Humans; Methods; Middle Aged; Progesterone; Protamines; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid | 1976 |
[Blood levels of testosterone and dihydrotestosterone in breast cancer].
Topics: Adult; Aged; Breast Neoplasms; Castration; Dihydrotestosterone; Female; Humans; Menopause; Middle Aged; Testosterone | 1976 |
The effects of androgens and antiandrogens on hormone-responsive human breast cancer in long-term tissue culture.
Topics: Androgen Antagonists; Androgens; Binding Sites; Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Cells, Cultured; Cyproterone; Cytoplasm; Dihydrotestosterone; DNA, Neoplasm; Estradiol; Estrenes; Female; Humans; Neoplasm Proteins; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid; Testosterone | 1976 |
Fractionation of diverse steroid-binding proteins: basic and clinical applications.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Carrier Proteins; Charcoal; Chickens; Chromatography, Agarose; Cytosol; Dextrans; Diethylstilbestrol; Dihydrotestosterone; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogens; Estrone; Female; Filtration; Humans; In Vitro Techniques; Ion Exchange; Oviducts; Receptors, Progesterone; Receptors, Steroid; Steroids | 1976 |
Testosterone metabolism in benign and malignant breast lesions.
Topics: Adenocarcinoma; Adenofibroma; Adolescent; Adult; Androstenedione; Breast Neoplasms; Carbon Radioisotopes; Cells, Cultured; Dihydrotestosterone; Female; Histocytochemistry; Humans; In Vitro Techniques; Mastitis; Methods; Middle Aged; Pregnancy; Testosterone | 1975 |
Oestradiol synthesis from C19 steroids by human breast cancers.
Topics: Androstane-3,17-diol; Androstenedione; Breast Neoplasms; Dihydrotestosterone; Estradiol; Humans; In Vitro Techniques; Testosterone | 1976 |
Expression and regulation of retinoic acid receptors in human breast cancer cells.
Topics: Breast Neoplasms; Carrier Proteins; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Progestins; Receptors, Retinoic Acid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1992 |
Secretion of breast gross cystic disease fluid proteins by T47D breast cancer cells in culture--modulation by steroid hormones.
Topics: Adipokines; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carcinoma; Carrier Proteins; Cell Division; Dihydrotestosterone; Estradiol; Female; Glycoproteins; Humans; Membrane Transport Proteins; Progesterone; Tumor Cells, Cultured | 1992 |
Regulation of androgen receptor mRNA and protein level by steroid hormones in human mammary cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Cyproterone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression Regulation, Neoplastic; Hormones; Humans; Immunohistochemistry; Progesterone Congeners; Radioligand Assay; Receptors, Androgen; RNA, Messenger; Steroids; Tumor Cells, Cultured | 1992 |
Additive stimulatory action of glucocorticoids and androgens on basal and estrogen-repressed apolipoprotein-D messenger ribonucleic acid levels and secretion in human breast cancer cells.
Topics: Actins; Apolipoproteins; Apolipoproteins D; Base Sequence; Breast Neoplasms; Cell Division; Dexamethasone; Dihydrotestosterone; DNA; Drug Synergism; Estradiol; Estrogens; Flow Cytometry; Humans; Molecular Sequence Data; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells.
Topics: Androgens; Breast Neoplasms; Dihydrotestosterone; Female; Gene Expression Regulation; Humans; Mifepristone; Pregnenediones; Receptors, Prolactin; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Estrogen-stimulated glucuronidation of dihydrotestosterone in MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Glucuronates; Humans; Kinetics; Tritium | 1992 |
Effects of dihydrotestosterone and hydroxyflutamide on androgen receptors in cultured human breast cancer cells (EVSA-T).
Topics: Androgen Antagonists; Breast Neoplasms; Cell Division; Dihydrotestosterone; Flutamide; Humans; Receptors, Androgen; Tumor Cells, Cultured | 1992 |
Androgen sensitivity of the new human breast cancer cell line MFM-223.
Topics: Breast Neoplasms; Cell Division; Dihydrotestosterone; Humans; Karyotyping; Phenotype; Receptors, Androgen; Receptors, Estrogen; Tumor Cells, Cultured | 1991 |
Rapid homologous up-regulation of binding capacity of androgen receptors in intact cells.
Topics: Breast Neoplasms; Cell Line; Dihydrotestosterone; Female; Humans; Kinetics; Receptors, Androgen; Temperature; Up-Regulation | 1991 |
A potential radioiodinated ligand for androgen receptor: 7 alpha-methyl-17 alpha-(2'-(E)-iodovinyl)-19-nortestosterone.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Chemical Phenomena; Chemistry; Dihydrotestosterone; Female; Humans; Iodine Radioisotopes; Molecular Structure; Nandrolone; Rats; Rats, Inbred Strains; Receptors, Androgen; Tumor Cells, Cultured; Uterus | 1991 |
Inhibition of cell cycle kinetics and proliferation by the androgen 5 alpha-dihydrotestosterone and antiestrogen N,n-butyl-N-methyl-11-[16' alpha-chloro-3',17 beta-dihydroxy-estra-1',3',5'-(10')triene-7' alpha-yl] undecanamide in human breast cancer ZR-75
Topics: Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Humans; Interphase; Tumor Cells, Cultured | 1991 |
Additive inhibitory effects of an androgen and the antiestrogen EM-170 on estradiol-stimulated growth of human ZR-75-1 breast tumors in athymic mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Implants; Estradiol; Estrogen Antagonists; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Ovariectomy; Transplantation, Heterologous | 1991 |
Interactions between estrogens, androgens, progestins, and glucocorticoids in ZR-75-1 human breast cancer cells.
Topics: Androgens; Androstenediol; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Estrogens; Gene Expression; Glucocorticoids; Glycoproteins; Humans; In Vitro Techniques; Insulin; Medroxyprogesterone; Medroxyprogesterone Acetate; Membrane Transport Proteins; Neoplasm Proteins; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tumor Cells, Cultured | 1990 |
Down-regulation of androgen receptor by progestins and interference with estrogenic or androgenic stimulation of mammary carcinoma cell growth.
Topics: Breast Neoplasms; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Down-Regulation; Estradiol; Humans; In Vitro Techniques; Medroxyprogesterone; Metribolone; Receptors, Androgen; Receptors, Estrogen | 1990 |
Evaluation of trilostane plus hydrocortisone in women with metastatic breast cancer and prior hormonal therapy exposure.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dihydrotestosterone; Female; Hormones; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Remission Induction | 1990 |
Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer.
Topics: Androgens; Apolipoproteins; Apolipoproteins D; Binding, Competitive; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Glycoproteins; Humans; Kinetics; Membrane Transport Proteins; Neoplasm Proteins; Progesterone; Tumor Cells, Cultured | 1990 |
Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells.
Topics: Apolipoproteins; Apolipoproteins D; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Division; Dexamethasone; Dihydrotestosterone; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Glycoproteins; Humans; Membrane Transport Proteins; Neoplasm Proteins; Piperidines; Raloxifene Hydrochloride; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1990 |
Androgens and breast cancer in premenopausal women.
Topics: Adult; Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Humans; Menopause; Middle Aged; Progesterone; Retrospective Studies; Sex Hormone-Binding Globulin; Testosterone | 1989 |
Progestins and androgens stimulate lipid accumulation in T47D breast cancer cells via their own receptors.
Topics: Acetates; Breast Neoplasms; Dihydrotestosterone; Dose-Response Relationship, Drug; Fatty Acids; Flutamide; Humans; In Vitro Techniques; Lipid Metabolism; Microscopy, Electron; Mifepristone; Norpregnadienes; Promegestone; Receptors, Androgen; Receptors, Progesterone; Triglycerides; Tumor Cells, Cultured | 1989 |
Antiestrogenic properties of keoxifene, trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells.
Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Humans; Piperidines; Polyunsaturated Alkamides; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured | 1989 |
[Hormonal regulation of GCDFP-15 secretion in breast tumors. Study of cultured cells].
Topics: Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Cells, Cultured; Depression, Chemical; Dihydrotestosterone; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Glycoproteins; Humans; Membrane Transport Proteins; Neoplasm Proteins; Organ Culture Techniques; Stimulation, Chemical; Tamoxifen | 1989 |
Antagonism between estrogens and androgens on GCDFP-15 gene expression in ZR-75-1 cells and correlation between GCDFP-15 and estrogen as well as progesterone receptor expression in human breast cancer.
Topics: Apolipoproteins; Apolipoproteins D; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Line; Dihydrotestosterone; Estradiol; Female; Gene Expression; Glycoproteins; Humans; Kinetics; Membrane Transport Proteins; Neoplasm Proteins; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Inhibitory effect of estrogens on GCDFP-15 mRNA levels and secretion in ZR-75-1 human breast cancer cells.
Topics: Apolipoproteins; Apolipoproteins D; Blotting, Northern; Breast Neoplasms; Carrier Proteins; Cell Division; Dexamethasone; Dihydrotestosterone; DNA Probes; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation; Glycoproteins; Humans; Membrane Transport Proteins; Neoplasm Proteins; Piperidines; Raloxifene Hydrochloride; RNA, Messenger | 1989 |
Endocrine effects of Trilostane: in vitro and in vivo studies.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Dihydrotestosterone; Female; Hormones; Humans; Hydrocortisone; Receptors, Cell Surface; Tumor Cells, Cultured | 1987 |
Comparative effects of 17 beta-estradiol, progestin R5020, tamoxifen and RU38486 on lactate dehydrogenase activity in MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Dexamethasone; Dihydrotestosterone; Estradiol; Estrenes; Female; Histocytochemistry; Humans; L-Lactate Dehydrogenase; Mifepristone; Norpregnadienes; Promegestone; Tamoxifen | 1989 |
Effects of tamoxifen on testosterone metabolism in postmenopausal women with breast cancer.
Topics: Aged; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Humans; Kinetics; Luteinizing Hormone; Menopause; Metabolic Clearance Rate; Middle Aged; Receptors, Estrogen; Tamoxifen; Testosterone | 1985 |
Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer.
Topics: Anilides; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Flutamide; Gonadal Steroid Hormones; Hormones; Humans; Middle Aged; Time Factors | 1988 |
Stimulatory effects of androgen and antiandrogen on the in vitro proliferation of human mammary carcinoma cells.
Topics: Androgen Antagonists; Androgens; Breast Neoplasms; Cell Division; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estrenes; Estrogens; Female; Humans; Metribolone; Receptors, Androgen; Tumor Cells, Cultured | 1988 |
In vitro modulation of prolactin binding to human mammary carcinoma cells by steroid hormones and prolactin.
Topics: Breast Neoplasms; Cell Line; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Kinetics; Mitosis; Prolactin; Receptors, Cell Surface; Receptors, Prolactin | 1985 |
Hormonal agents and treatment of cancer.
Topics: Androgens; Breast Neoplasms; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Female; Flutamide; Hormones; Humans; Male; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen | 1986 |
Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line.
Topics: Androgen Antagonists; Androstenedione; Breast Neoplasms; Cell Division; Cell Line; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Flutamide; Humans; Piperidines; Raloxifene Hydrochloride; Receptors, Androgen; Receptors, Estrogen; Testosterone | 1988 |
Testicular descent: androgen receptors in cultured porcine gubernaculum cells.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Cells, Cultured; Centrifugation; Dihydrotestosterone; Estradiol; Estrenes; Fibroblasts; Humans; Hydrocortisone; Male; Metribolone; Receptors, Androgen; Swine; Testis; Tumor Cells, Cultured | 1988 |
Identification and androgen regulation of two proteins released by T47D human breast cancer cells.
Topics: Androgens; Antibodies, Monoclonal; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Line; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression Regulation; Glycoproteins; Humans; Membrane Transport Proteins; Molecular Weight; Neoplasm Proteins; Promegestone; Receptors, Androgen; Seminal Plasma Proteins; Zn-Alpha-2-Glycoprotein | 1987 |
Isolation and sequencing of a cDNA clone for a prolactin-inducible protein (PIP). Regulation of PIP gene expression in the human breast cancer cell line, T-47D.
Topics: Amino Acid Sequence; Apolipoproteins; Apolipoproteins D; Base Sequence; Breast Neoplasms; Carrier Proteins; Cell Line; Cloning, Molecular; Dexamethasone; Dihydrotestosterone; DNA; Female; Gene Expression Regulation; Genes; Glycoproteins; Humans; Hydrocortisone; Membrane Transport Proteins; Molecular Sequence Data; Neoplasm Proteins; RNA, Messenger; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1987 |
Multicenter study of trilostane: a new hormonal agent in advanced postmenopausal breast cancer.
Topics: Breast Neoplasms; Carcinoma; Dexamethasone; Dihydrotestosterone; Female; Humans; Menopause; Multi-Institutional Systems | 1987 |
Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.
Topics: Aminoglutethimide; Animals; Azasteroids; Breast Neoplasms; Cell Cycle; Cell Line; Danazol; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Humans; Pancreatic Neoplasms; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Tamoxifen | 1986 |
Androgens increase osteoblast-stimulating activity of human breast cancer cells in vitro.
Topics: Androgens; Bone Neoplasms; Breast Neoplasms; Cell Line; Culture Media; Dihydrotestosterone; DNA; Dose-Response Relationship, Drug; Female; Growth Substances; Humans; Osteoblasts | 1986 |
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response.
Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen | 1986 |
Endogenous C19-steroids and oestradiol levels in human primary breast tumour tissues and their correlation with androgen and oestrogen receptors.
Topics: Adult; Aged; Androgens; Androstenedione; Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Menopause; Middle Aged; Radioimmunoassay; Receptors, Androgen; Receptors, Estrogen; Testosterone | 1986 |
The relationship between growth and androstenedione metabolism in four cell lines of human breast carcinoma cells in culture.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Aromatase; Breast Neoplasms; Cell Division; Cell Line; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Oxidoreductases; Testosterone | 1985 |
Serum steroid binding proteins and the bioavailability of estradiol in relation to breast diseases.
Topics: Aged; Biological Availability; Breast Diseases; Breast Neoplasms; Dihydrotestosterone; Estradiol; Female; Humans; Middle Aged; Radioimmunoassay; Serum Albumin; Sex Hormone-Binding Globulin; Transcortin | 1985 |
Onset of androgen action in MCF-7 human breast cancer cells is not accompanied by receptor depletion.
Topics: Androgens; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Estrenes; Female; Humans; Metribolone; Potassium Chloride; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid | 1985 |
Trilostane therapy for advanced breast cancer.
Topics: Aged; Breast Neoplasms; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Receptors, Estrogen | 1985 |
Hormonal changes in postmenopausal women with breast cancer treated with trilostane and dexamethasone.
Topics: Adrenal Cortex Hormones; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estrone; Female; Gonadal Steroid Hormones; Humans; Menopause; Neoplasm Metastasis | 1985 |
Oestradiol synthesis by a human breast carcinoma.
Topics: Androstenediols; Androstenedione; Binding Sites; Breast Neoplasms; Carcinoma; Dihydrotestosterone; Estradiol; Female; Humans; Microtomy; Middle Aged; Prolactin; Radioactivity; Testosterone; Tritium | 1974 |
Steroid metabolism by human breast tumours.
Topics: 17-Ketosteroids; Androstanes; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; In Vitro Techniques; Mastectomy | 1970 |
Steroidogenesis in human and rat mammary adenocarcinoma.
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Breast Neoplasms; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Rats; Testosterone | 1972 |
Dihydrotestosterone receptor in human mammary cancer.
Topics: Breast Neoplasms; Dihydrotestosterone; Electrophoresis, Starch Gel; Estradiol; Female; Humans; Methods; Receptors, Cell Surface; Tritium | 1973 |
Steroid metabolism by human breast and rat mammary carcinomata.
Topics: Adult; Androstanes; Animals; Benz(a)Anthracenes; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cells, Cultured; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Hydroxysteroids; Mammary Neoplasms, Experimental; Middle Aged; Oxidation-Reduction; Rats; Solvents; Spectrophotometry, Ultraviolet; Testosterone; Tritium | 1974 |
[Relation between testosterone metabolism and dihydrotestosterone receptor in human breast tumors (author's transl)].
Topics: Adult; Aged; Androstenedione; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Cytosol; Dihydrotestosterone; Female; Humans; In Vitro Techniques; Middle Aged; Oxidoreductases; Receptors, Drug; Testosterone | 1974 |
[The behavior of erythropoietin in aregenerative disorders of erythropoiesis during therapy with anabolic steroids].
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Bone Marrow Examination; Bone Neoplasms; Breast Neoplasms; Dihydrotestosterone; Erythropoiesis; Erythropoietin; Female; Hepatitis; Humans; Iron; Iron Radioisotopes; Male; Oxymetholone; Prednisolone; Sepsis; Transfusion Reaction | 1974 |
Relative oestrogen concentrations in human tumours.
Topics: Adipose Tissue; Breast Neoplasms; Carbon Isotopes; Dihydrotestosterone; Estradiol; Estrogens; Female; Humans; Neoplasms; Testosterone; Time Factors; Tritium | 1970 |