Page last updated: 2024-08-21

dihydrotestosterone and Blood Pressure, High

dihydrotestosterone has been researched along with Blood Pressure, High in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.33)18.7374
1990's2 (6.67)18.2507
2000's9 (30.00)29.6817
2010's12 (40.00)24.3611
2020's3 (10.00)2.80

Authors

AuthorsStudies
Perusquía, M1
Andreeva, EN; Bondarenko, IZ; Filatova, VA; Ioutsi, VA; Mel'nichenko, GA; Mokrysheva, NG; Rozhivanov, RV1
Alonso-Miguel, D; Arenas Bermejo, C; Clares Moral, I; Cuesta-Alvaro, P; García San José, P; Pérez Alenza, MD1
Hankins, GDV; Kumar, S; Mishra, JS; More, AS1
Contreras, D; Herrera, N; Perusquía, M1
Capdevila, JH; Cheng, J; Ding, Y; Falck, JR; Garcia, V; Gotlinger, K; Manthati, VL; Mei, S; Schwartzman, ML; Weidenhammer, A; Wu, CC; Zhang, F1
Capdevila, JH; Dimitrova, I; Ding, Y; Falck, JR; Garcia, V; Joseph, G; Manthati, VL; Schwartzman, ML; Weidenhammer, A; Wu, CC; Zhang, F1
Honda, M; Kinoshita, Y; Oikawa, R; Saito, M; Sejima, T; Shimizu, S; Tomita, S; Tsounapi, P1
Bui, E; do Carmo, JM; Granger, JP; Hall, JE; Lima, R; Maranon, R; Moulana, M; Reckelhoff, JF; Smith, AD; Spradley, FT; Thomas, RL; Zhang, H1
Bernstein, KE; Capdevila, JH; Dakarapu, R; Ding, Y; Falck, JR; Garcia, V; Gotlinger, K; Joseph, G; Schwartzman, ML; Shkolnik, B; Zhang, FF1
Bi, J; Hoang, V; Mohankumar, SM; Vyas, AK1
Dalmasso, C; Maranon, R; Moulana, M; Patil, C; Reckelhoff, JF; Romero, DG1
Ferrer, M; Herrera, N; Perusquía, M; Stallone, JN1
Funder, JW2
Cheng, J; Falck, JR; Gotlinger, KH; Jat, JL; Kelkar, M; Schwartzman, ML; Wu, CC; Zhang, FF; Zhang, Y1
Capdevila, JH; Marji, JS; Nakagawa, K; Schwartzman, ML; Waterman, MR1
Jesmin, S; Kitabatake, A; Mowa, CN; Sakuma, I; Togashi, H; Ueno, K; Yamaguchi, T; Yoshioka, M1
Lombard, JH; Roman, RJ1
Cheng, J; Deng, H; Ishizuka, T; Kemp, R; Nasjletti, A; Schwartzman, ML; Singh, H1
Quigley, R1
Ganten, D; Hackenthal, E; Hellmann, W; Klett, C1
Iitaka, M; Inaba, M; Katayama, S; Morita, T; Sasano, H; Yamanaka, K1
Adas, F; Breyer, MD; Capdevila, JH; Falck, JR; Holla, VR; Imig, JD; Keeney, DS; Kovacs, WJ; Magnuson, MA; Olsen, N; Price, E; Waterman, MR; Zhao, X1
Füessl, HS1
Corvol, P; Freifeld, M; Mahoudeau, J; Menard, J; Michaud, A1
Guberan, E1
Baba, K; Doi, Y; Hashiba, K; Kawai, K; Nakamura, T; Senba, M; Tsuchiyama, H; Yamaguchi, T1
Griffing, GT; Melby, JC1
Friemann, J; Müller, KM1

Reviews

4 review(s) available for dihydrotestosterone and Blood Pressure, High

ArticleYear
Androgens and Non-Genomic vascular responses in hypertension.
    Biochemical pharmacology, 2022, Volume: 203

    Topics: Androgens; Dihydrotestosterone; Humans; Hypertension; Male; Testosterone; Vasodilation

2022
Aldosterone, hypertension and heart failure: insights from clinical trials.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:9

    Topics: Aldosterone; Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Dihydrotestosterone; Drug Therapy, Combination; Enzyme Inhibitors; Female; Heart Failure; Heptanoic Acids; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Mice; Mineralocorticoid Receptor Antagonists; Ouabain; Pyrroles; Quinolines; Rats; Spironolactone

2010
Does 20-hydroxyeicosatetraenoic acid contribute to sex differences in cardiovascular risk by increasing oxidative stress?
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:1

    Topics: Animals; Cardiovascular Diseases; Dihydrotestosterone; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Oxidative Stress; Risk Factors; Sex Characteristics

2007
Androgens stimulate proximal tubule transport.
    Gender medicine, 2008, Volume: 5 Suppl A

    Topics: Androgens; Angiotensin II; Animals; Blood Pressure; Dihydrotestosterone; Disease Models, Animal; Hypertension; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Up-Regulation

2008

Trials

1 trial(s) available for dihydrotestosterone and Blood Pressure, High

ArticleYear
Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by trilostane, an inhibitor of adrenal steroidogenesis.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:4

    Topics: Aldosterone; Blood Pressure; Dihydrotestosterone; Diuretics; Double-Blind Method; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Prospective Studies; Random Allocation

1989

Other Studies

25 other study(ies) available for dihydrotestosterone and Blood Pressure, High

ArticleYear
[Features of steroidogenesis and arterial hypertension in men in different types of "physiological" male hyperandrogenism].
    Problemy endokrinologii, 2023, May-11, Volume: 69, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenedione; Dihydrotestosterone; Estradiol; Female; Humans; Hyperandrogenism; Hypertension; Male; Ovarian Diseases; Testosterone

2023
Changes in systolic blood pressure in dogs with pituitary dependent hyperadrenocorticism during the first year of trilostane treatment.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:1

    Topics: Adrenocortical Hyperfunction; Animals; Blood Pressure; Dihydrotestosterone; Dog Diseases; Dogs; Hypertension; Prospective Studies

2021
Hyperandrogenemia reduces endothelium-derived hyperpolarizing factor-mediated relaxation in mesenteric artery of female rats.
    Biology of reproduction, 2017, Jun-01, Volume: 96, Issue:6

    Topics: Animals; Biological Factors; Blood Pressure; Connexin 43; Dihydrotestosterone; Drug Implants; Endothelium, Vascular; Female; Hypertension; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Vasodilation

2017
Hypotestosteronemia is an important factor for the development of hypertension: elevated blood pressure in orchidectomized conscious rats is reversed by different androgens.
    Endocrine, 2019, Volume: 65, Issue:2

    Topics: Androgens; Animals; Blood Pressure; Dihydrotestosterone; Drug Evaluation, Preclinical; Endothelin-1; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Orchiectomy; Rats, Inbred WKY; Rats, Wistar; Testosterone

2019
Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.
    Journal of the American Society of Nephrology : JASN, 2013, Volume: 24, Issue:8

    Topics: Androgens; Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Dihydrotestosterone; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mice; Up-Regulation

2013
20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.
    American journal of physiology. Renal physiology, 2013, Sep-01, Volume: 305, Issue:5

    Topics: Animals; Blood Pressure; Dihydrotestosterone; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice; Rats; Rats, Sprague-Dawley; Renal Artery; Reserpine

2013
Prostatic ischemia induces ventral prostatic hyperplasia in the SHR; possible mechanism of development of BPH.
    Scientific reports, 2014, Jan-22, Volume: 4

    Topics: Actins; Animals; Biomarkers; Blood Pressure; Dihydrotestosterone; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Male; Malondialdehyde; Oxidative Stress; Prostate; Prostatic Hyperplasia; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Transforming Growth Factor beta1

2014
Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Adrenergic Antagonists; Animals; Arterial Pressure; Dihydrotestosterone; Disease Models, Animal; Female; Hormone Antagonists; Hyperandrogenism; Hypertension; Hypothalamus; Kidney; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Signal Transduction; Sympathectomy; Sympathetic Nervous System; Time Factors

2015
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Transgenic; Microvessels; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors; Vascular Remodeling

2015
Liraglutide improves hypertension and metabolic perturbation in a rat model of polycystic ovarian syndrome.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Abdominal Fat; Animals; Blood Pressure; Cholesterol; Dihydrotestosterone; Disease Models, Animal; Estrous Cycle; Female; Glucose; Hypertension; Liraglutide; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Telemetry; Weight Gain

2015
20-HETE and CYP4A2 ω-hydroxylase contribute to the elevated blood pressure in hyperandrogenemic female rats.
    American journal of physiology. Renal physiology, 2016, 07-01, Volume: 311, Issue:1

    Topics: Androgens; Animals; Body Weight; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Female; Gene Deletion; Gene Knockout Techniques; Hydroxyeicosatetraenoic Acids; Hyperandrogenism; Hypertension; Microcirculation; Rats; Rats, Inbred Dahl; Renal Circulation; Steroids

2016
Antihypertensive effects of androgens in conscious, spontaneously hypertensive rats.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 167

    Topics: Androgens; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channels, L-Type; Consciousness; Dihydrotestosterone; Hypertension; Male; Orchiectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Risk Factors; Testosterone

2017
Trilostane, FAD286, and the role of aldosterone in the central regulation of blood pressure: focus on "Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats".
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Dihydrotestosterone; Enzyme Inhibitors; Heart Rate; Hypertension; Hypothalamus; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Sodium; Sodium Chloride, Dietary; Steroid Hydroxylases

2009
Androgen-dependent hypertension is mediated by 20-hydroxy-5,8,11,14-eicosatetraenoic acid-induced vascular dysfunction: role of inhibitor of kappaB Kinase.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4

    Topics: Androgens; Animals; Blood Pressure; Dihydrotestosterone; Endothelium, Vascular; Hydroxyeicosatetraenoic Acids; Hypertension; I-kappa B Kinase; Rats; Rats, Sprague-Dawley; Renal Artery; Sesquiterpenes; Vasoconstriction

2011
Androgen-mediated induction of the kidney arachidonate hydroxylases is associated with the development of hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:4

    Topics: Animals; Blood Pressure; Cells, Cultured; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Induction; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sex Characteristics; Testosterone

2003
Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Animals; Aromatase; Attention Deficit Disorder with Hyperactivity; Capillaries; Cerebrovascular Circulation; Dihydrotestosterone; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Frontal Lobe; Gonadal Steroid Hormones; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Stroke; Testosterone; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2004
Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:1

    Topics: Acetylcholine; Amidines; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Dihydrotestosterone; Drug Synergism; Endothelium, Vascular; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renal Artery; Superoxides; Vasodilation; Vasodilator Agents

2007
Modulation of tissue angiotensinogen gene expression by glucocorticoids, estrogens, and androgens in SHR and WKY rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:4

    Topics: Angiotensinogen; Animals; Dexamethasone; Dihydrotestosterone; Drug Resistance; Ethinyl Estradiol; Female; Gene Expression Regulation; Hypertension; Kinetics; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Steroids; Tissue Distribution

1993
A case of renin-producing adrenocortical cancer.
    Endocrine journal, 2000, Volume: 47, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Biopsy, Needle; Catecholamines; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Enzyme Inhibitors; Female; Glucocorticoids; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hypertension; Hypokalemia; Middle Aged; Mitotane; Muscle Weakness; Neoplasm Metastasis; Renin; Thirst; Tomography, X-Ray Computed

2000
Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9

    Topics: Androgens; Animals; Arachidonic Acid; Blood Pressure; Castration; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Enzyme Induction; Female; Gene Deletion; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mice; Mice, Knockout; Microsomes; Mixed Function Oxygenases; Renal Circulation; RNA, Messenger; Sex Characteristics; Testosterone; Vascular Resistance

2001
[Secondary forms of hypertension. 5. Hypertension caused by Cushing syndrome and Conn's disease].
    MMW Fortschritte der Medizin, 2002, Feb-28, Volume: 144, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Algorithms; Cushing Syndrome; Diagnosis, Differential; Dihydrotestosterone; Diuretics; Enzyme Inhibitors; Humans; Hyperaldosteronism; Hypertension; Magnetic Resonance Angiography; Mineralocorticoid Receptor Antagonists; Pituitary Neoplasms; Spironolactone; Tomography, X-Ray Computed

2002
Antiandrogenic effect of spirolactones: mechanism of action.
    Endocrinology, 1975, Volume: 97, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Binding, Competitive; Canrenoic Acid; Cell Nucleus; Cyproterone; Cytosol; Dihydrotestosterone; Hyperaldosteronism; Hypertension; Male; Prostate; Rats; Receptors, Cell Surface; Spironolactone; Tritium

1975
Surprising decline of cardiovascular mortality in Switzerland: 1951-1976.
    Journal of epidemiology and community health, 1979, Volume: 33, Issue:2

    Topics: Cardiovascular Diseases; Contraceptives, Oral; Dihydrotestosterone; Feeding Behavior; Female; Humans; Hypertension; Male; Rheumatic Heart Disease; Sex Factors; Smoking; Switzerland; Testosterone

1979
Effect of the adrenal inhibitor trilostane on the morphology of the adrenocortical cells of Dahl salt-sensitive and Dahl salt-resistant rats.
    International journal of experimental pathology, 1991, Volume: 72, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Dihydrotestosterone; Hypertension; Male; Microscopy, Electron; Organ Size; Rats; Rats, Inbred Strains

1991
Effects of trilostane in normotensive and hypertensive rats.
    Cardiology, 1985, Volume: 72 Suppl 1

    Topics: 3-Hydroxysteroid Dehydrogenases; Adipose Tissue; Adrenal Glands; Animals; Blood Pressure; Dihydrotestosterone; Dose-Response Relationship, Drug; Hypertension; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1985