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dihydrolipoic acid and Myocardial Ischemia

dihydrolipoic acid has been researched along with Myocardial Ischemia in 4 studies

dihydrolipoic acid: RN given refers to parent cpd without isomeric designation
dihydrolipoic acid : A thio-fatty acid that is reduced form of lipoic acid. A potent antioxidant shown to directly destroy superoxide, hydroperoxy and hydroxyl radicals; also has neuroprotective and anti-tumour effects.
dihydrolipoate : The conjugate base of dihydrolipoic acid.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"To reduce reperfusion injury, conditions were ameliorated including the treatment with antioxidants, lipoate or dihydrolipoate."1.31Lipoate ameliorates ischemia-reperfusion in animal models. ( Freisleben, HJ, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schönheit, K1
Gille, L1
Nohl, H1
Haramaki, N1
Packer, L1
Assadnazari, H1
Zimmer, G1
Freisleben, HJ2

Other Studies

4 other studies available for dihydrolipoic acid and Myocardial Ischemia

ArticleYear
Effect of alpha-lipoic acid and dihydrolipoic acid on ischemia/reperfusion injury of the heart and heart mitochondria.
    Biochimica et biophysica acta, 1995, Jun-09, Volume: 1271, Issue:2-3

    Topics: Animals; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury

1995
Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid.
    Biochemical and biophysical research communications, 1993, Nov-15, Volume: 196, Issue:3

    Topics: Analysis of Variance; Animals; Biomarkers; Coronary Circulation; Food, Fortified; Hypoxia; In Vitro

1993
Lipoic acid reduces ischemia-reperfusion injury in animal models.
    Toxicology, 2000, Aug-07, Volume: 148, Issue:2-3

    Topics: Adenosine Triphosphatases; Animals; Creatine Kinase; Disease Models, Animal; Heart; Hindlimb; In Vit

2000
Lipoate ameliorates ischemia-reperfusion in animal models.
    Clinical hemorheology and microcirculation, 2000, Volume: 23, Issue:2-4

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Aorta, Thoracic; Cell Hypoxia; Constriction; Creatine

2000