dihydroergotoxine has been researched along with Anemia--Sickle-Cell* in 4 studies
4 other study(ies) available for dihydroergotoxine and Anemia--Sickle-Cell
Article | Year |
---|---|
Hydergine and vincamine derivative LD 4298 exhibit no anti-sickling properties in vitro.
Amongst the treatments proposed for Sickle Cell disease Ergot derivatives and extracts from Pervinca have been proposed. We have studied in vitro the effect of Hydergine and LD 4298 on Sickle Cells and Sickle Hemoglobin according to the following four parameters: percentage of sickling, potassium leak, minimum gelation concentration and speed of gelation. In these studies no anti-sickling effect was detected. Moreover Hydergine at 50 microgram/ml increased spontaneous potassium loss without any anti-sickling effect. One can conclude that these two drugs have no effect on sickling. Topics: Anemia, Sickle Cell; Dihydroergotoxine; Drug Evaluation; Humans; Vinca Alkaloids; Vincamine | 1979 |
Hydergine and vincamine derivative LD 4298 exhibit no anti-sickling properties in vitro.
Amongst the treatments proposed for Sickle Cell disease Ergot derivatives and extracts from Pervinca have been proposed. We have studied in vitro the effect of Hydergine and LD 4298 on Sickle Cells and Sickle Hemoglobin according to the following four parameters : percentage of sickling, potassium leak, minimum gelation concentration and speed of gelation. In these studies no anti-sickling effect was detected. Moreover Hydergine at 50 microgram/ml increased spontaneous potassium loss without any anti-sickling effect. One can conclude that these two drugs have no effect on sickling. Topics: Anemia, Sickle Cell; Dihydroergotoxine; Erythrocyte Membrane; Erythrocytes; Humans; Potassium; Vinca Alkaloids; Vincamine | 1978 |
[Sickle cell disease in children. Value of hygergine in the treatment and prophylaxis of the crisis].
Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Dihydroergotoxine; Ergoloid Mesylates; Humans; Infant | 1975 |
[Prevention of drepanocytic painful crises with hydergine].
Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Dihydroergotoxine; Ergoloid Mesylates; Humans; Middle Aged; Pain | 1974 |