dihydroergotoxine and Anemia--Sickle-Cell

dihydroergotoxine has been researched along with Anemia--Sickle-Cell* in 4 studies

Other Studies

4 other study(ies) available for dihydroergotoxine and Anemia--Sickle-Cell

Article	Year
Hydergine and vincamine derivative LD 4298 exhibit no anti-sickling properties in vitro. Nouvelle revue francaise d'hematologie, 1979, Jan-30, Volume: 20, Issue:4 Amongst the treatments proposed for Sickle Cell disease Ergot derivatives and extracts from Pervinca have been proposed. We have studied in vitro the effect of Hydergine and LD 4298 on Sickle Cells and Sickle Hemoglobin according to the following four parameters: percentage of sickling, potassium leak, minimum gelation concentration and speed of gelation. In these studies no anti-sickling effect was detected. Moreover Hydergine at 50 microgram/ml increased spontaneous potassium loss without any anti-sickling effect. One can conclude that these two drugs have no effect on sickling. Topics: Anemia, Sickle Cell; Dihydroergotoxine; Drug Evaluation; Humans; Vinca Alkaloids; Vincamine	1979
Hydergine and vincamine derivative LD 4298 exhibit no anti-sickling properties in vitro. Nouvelle revue francaise d'hematologie, 1978, Volume: 20, Issue:4 Amongst the treatments proposed for Sickle Cell disease Ergot derivatives and extracts from Pervinca have been proposed. We have studied in vitro the effect of Hydergine and LD 4298 on Sickle Cells and Sickle Hemoglobin according to the following four parameters : percentage of sickling, potassium leak, minimum gelation concentration and speed of gelation. In these studies no anti-sickling effect was detected. Moreover Hydergine at 50 microgram/ml increased spontaneous potassium loss without any anti-sickling effect. One can conclude that these two drugs have no effect on sickling. Topics: Anemia, Sickle Cell; Dihydroergotoxine; Erythrocyte Membrane; Erythrocytes; Humans; Potassium; Vinca Alkaloids; Vincamine	1978
[Sickle cell disease in children. Value of hygergine in the treatment and prophylaxis of the crisis]. Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1975, Volume: 20, Issue:1 Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Dihydroergotoxine; Ergoloid Mesylates; Humans; Infant	1975
[Prevention of drepanocytic painful crises with hydergine]. Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1974, Volume: 19, Issue:2 Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Dihydroergotoxine; Ergoloid Mesylates; Humans; Middle Aged; Pain	1974