dihydroergotoxine and Acromegaly

dihydroergotoxine has been researched along with Acromegaly* in 2 studies

Other Studies

2 other study(ies) available for dihydroergotoxine and Acromegaly

ArticleYear
Effect of dihydroergokryptine administration on serum prolactin and growth hormone levels in normal, hyperprolactinaemic and acromegalic subjects: evidence of potent and long-lasting pituitary dopamine receptor stimulation.
    European journal of clinical pharmacology, 1985, Volume: 27, Issue:6

    The endocrine effects of a relatively potent dopaminergic agent, dihydroergokryptine, have been studied in normal subjects, and in hyperprolactinaemic and acromegalic patients. A single 6 mg oral dose of the drug caused a marked, long lasting fall in prolactin (PRL) plasma levels in healthy subjects, in hyperprolactinaemic patients and in normoprolactinaemic acromegalics. Growth hormone (GH) levels decreased in 1-DOPA - responder, acromegalic patients, but dihydroergokryptine did not affect GH levels in normal volunteers or in 1-DOPA non-responder, acromegalic patients. The PRL- and GH- lowering activity of 6 mg dihydroergokryptine was significantly greater than that of 6 mg dihydroergocristine, and was similar to that of an oral dose of 500 mg 1-DOPA.

    Topics: Acromegaly; Adenoma; Adult; Aged; Dihydroergotoxine; Female; Growth Hormone; Humans; Levodopa; Male; Middle Aged; Pituitary Gland; Pituitary Neoplasms; Prolactin; Receptors, Dopamine; Time Factors

1985
Effect of dihydroergocristine administration on serum prolactin and growth hormone levels in normal, hyperprolactinaemic, and acromegalic subjects: further evidence for pituitary dopamine deficiency in these conditions.
    Acta endocrinologica, 1983, Volume: 103, Issue:1

    Topics: Acromegaly; Adenoma; Adolescent; Adult; Amenorrhea; Dihydroergotoxine; Dopamine; Female; Growth Hormone; Humans; Levodopa; Male; Middle Aged; Nomifensine; Pituitary Gland; Pituitary Neoplasms; Prolactin

1983