dihydroceramide has been researched along with Hip-Fractures* in 1 studies
1 other study(ies) available for dihydroceramide and Hip-Fractures
| Article | Year |
|---|---|
A pilot study examining the impact of exercise training on skeletal muscle genes related to the TLR signaling pathway in older adults following hip fracture recovery.
Older adults after hip fracture surgery experience progressive muscle atrophy and weakness, limiting full recovery. Further understanding of the molecular mechanisms in muscle with adaptation to exercise training in this vulnerable population is necessary. Therefore, we conducted a pilot study to investigate the skeletal muscle inflammatory and ceramide biosynthesis gene expression levels associated with the toll-like receptor (TLR) pathway before (Pre) and following a 3-mo multicomponent exercise training program in older adults (3M, 4F; 78.4 ± 13.3 yr; 25.5 ± 2.3 kg/m. These pilot data demonstrate that 3 mo of exercise training in older adults recovering from hip fracture surgery was able to mitigate skeletal muscle gene expression related to inflammation and ceramide metabolism while also improving surgical limb lean tissue, strength, and physical function. Topics: Adaptation, Physiological; Aged; Ceramides; Exercise; Extremities; Female; Gene Expression; Hip Fractures; Humans; Inflammation; Male; Muscle Strength; Pilot Projects; Quadriceps Muscle; Resistance Training; Signal Transduction; Toll-Like Receptors; Walking | 2017 |