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dihydralazine and Chemical and Drug Induced Liver Injury

dihydralazine has been researched along with Chemical and Drug Induced Liver Injury in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199017 (58.62)18.7374
1990's8 (27.59)18.2507
2000's1 (3.45)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Enat, R; Nagler, A1
Roschlau, G1
Benhamou, JP; Bernuau, J; Degott, C; Pariente, EA; Pessayre, D1
Kendrey, G; László, B2
Mölleken, K; Rüger, K1
Manns, MP; Straub, P; Van Pelt, FN1
Beaune, P; Belloc, C; Bourdi, M; Gautier, JC; Guengerich, FP; Valadon, P1
Beaune, PH; Belloc, C; Bourdi, M; Dansette, P; Gauffre, A; Lecoeur, S; Mansuy, D1
Beaune, PH; Lecoeur, S1
André, C; Beaune, PH; Belloc, C; Gauffre, A1
Manns, MP; Obermayer-Straub, P; Strassburg, CP1
Cueni, B; Knoblauch, M; Schmid, M; Spycher, M1
Andre, C; Beaune, PH; Belloc, C; Bourdi, M; Gautier, JC; Guillouzo, A; Larrey, D; Mircheva, J1
Watkins, PB1
Beaune, PH; Bernuau, J; Bourdi, M; Guengerich, FP; Iwasaki, M; Larrey, D; Nataf, J; Pessayre, D1
Baumgarten, R; Fengler, JD; Franke, G; Krüger, R; Reichardt, R; Siegmund, W1
Henschel, L; Hoffmann, A; Jorke, D; Rechenbach, C; Reinhardt, M1
Colombel, JF; Cortot, A; Dessaint, JP; Gerard, A; Houcke, M; Paris, JC; Prin, L1
Hass, S; Roschlau, G; Schmehl, V1
Bergert, A; Justus, J; Kunze, P; Machnik, G; Müller, R; Reinhardt, M; Schulz, H; Stein, G; Thiele, R1
Kunze, KD; Porst, H; Tschöpel, L1
Kunze, KD; Lohmann, J; Porst, H; Tschöpel, L1
Kantola, I; Leino, R; Seppälä, P; Viikari, J1
Jahn, G; Krombholz, B; Machnik, G; Reinhardt, M1

Reviews

4 review(s) available for dihydralazine and Chemical and Drug Induced Liver Injury

ArticleYear
Molecular basis of drug-induced immunological liver injury.
    Seminars in liver disease, 1995, Volume: 15, Issue:3

    Topics: Animals; Antibody Formation; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug-Related Side Effects and Adverse Reactions; Halothane; Haptens; Humans; Liver; Liver Diseases; Ticrynafen

1995
Anti-cytochrome P450 autoantibodies in drug-induced disease.
    European journal of haematology. Supplementum, 1996, Volume: 60

    Topics: Autoantibodies; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dihydralazine; Humans; Ticrynafen

1996
Immunotoxicology of the liver: adverse reactions to drugs.
    Journal of hepatology, 1997, Volume: 26 Suppl 2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersensitivity; Halothane; Humans; Immunity; Ticrynafen

1997
Target proteins in human autoimmunity: cytochromes P450 and UDP- glucuronosyltransferases.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14, Issue:5

    Topics: Autoantibodies; Autoimmunity; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dihydralazine; Glucuronosyltransferase; Hepatitis C, Chronic; Hepatitis, Autoimmune; Humans; Polyendocrinopathies, Autoimmune

2000

Other Studies

25 other study(ies) available for dihydralazine and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Liver damage due to reserpine hypersensitivity].
    Harefuah, 1984, Volume: 107, Issue:5-6

    Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Middle Aged; Reserpine

1984
[Dihydralazine-induced hepatitis with bridging necrosis. A clinico-pathologic survey of 20 cases].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1983, Volume: 127, Issue:5-6

    Topics: Adolescent; Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis; Recurrence; Time Factors

1983
Dihydralazine hepatitis: report of a case and review of the literature.
    Digestion, 1983, Volume: 27, Issue:1

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Hepatic Encephalopathy; Humans; Hydralazine; Hypertension; Liver; Male; Middle Aged; Prothrombin Time

1983
[Morphologic observations in liver damage in patients taking Depressan (dihydralazinum sulfuricum)].
    Morphologiai es igazsagugyi orvosi szemle, 1981, Volume: 21, Issue:4

    Topics: Antihypertensive Agents; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis

1981
[Acute liver damage in patients treated with a depressant (dihydralazine sulfate)].
    Orvosi hetilap, 1981, Dec-27, Volume: 122, Issue:52

    Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis

1981
[Rare liver damage caused by an antihypertensive and anti-arrhythmic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Apr-01, Volume: 35, Issue:7

    Topics: Adult; Ajmaline; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dihydralazine; Female; Humans; Hydralazine; Liver; Necrosis

1980
Immunotoxicology and expression of human cytochrome P450 in microorganisms.
    Toxicology, 1993, Oct-05, Volume: 82, Issue:1-3

    Topics: Amino Acid Sequence; Animals; Autoantibodies; Bacteria; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dihydralazine; Humans; Microsomes, Liver; Molecular Sequence Data; Rabbits; Saccharomyces cerevisiae; Ticrynafen

1993
Epitope mapping of human CYP1A2 in dihydralazine-induced autoimmune hepatitis.
    Pharmacogenetics, 1997, Volume: 7, Issue:3

    Topics: Antibody Specificity; Autoantibodies; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Dihydralazine; DNA, Complementary; Epitope Mapping; Humans; In Vitro Techniques; Microsomes, Liver

1997
[Dihydralazine-induced hepatitis].
    Schweizerische medizinische Wochenschrift, 1977, May-14, Volume: 107, Issue:19

    Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic

1977
[Dihydralazine-induced acute hepatitis with IgM deficiency].
    Schweizerische medizinische Wochenschrift, 1977, May-14, Volume: 107, Issue:19

    Topics: Acetylation; Aged; Antibodies; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersensitivity; Female; Humans; Hydralazine; Hyperbilirubinemia; Hypertension; Immunoglobulin M; Liver; Male; Middle Aged; Mitochondria; Phenotype

1977
Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: specificity of autoantibodies and inductive capacity of the drug.
    Molecular pharmacology, 1992, Volume: 42, Issue:2

    Topics: Animals; Antibody Specificity; Autoantibodies; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Dihydralazine; Enzyme Induction; Humans; Liver; Male; Microsomes, Liver; Oxidoreductases; Rats; Rats, Inbred Strains

1992
Antimicrosomal antibodies: what are they telling us?
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:2

    Topics: Autoantibodies; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Dihydralazine; Humans; Immunoblotting; Microsomes, Liver; Oxidoreductases

1991
Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P-450IA2. A specific marker of dihydralazine-induced hepatitis.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:6

    Topics: Autoantibodies; Blotting, Western; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dihydralazine; Endoplasmic Reticulum; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases

1990
Kinetics of antipyrine and sulfamethazine in patients recovered from dihydralazine-hepatitis.
    International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:4

    Topics: Acetylation; Adult; Aged; Antipyrine; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Male; Middle Aged; Oxidation-Reduction; Sulfamethazine

1989
[Biotransformation in patients following Depressan-induced hepatitis].
    Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR, 1989, Volume: 49, Issue:1

    Topics: Adult; Aged; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Follow-Up Studies; Humans; Hydralazine; Liver Function Tests; Male; Middle Aged; Sulfamethazine

1989
[Dihydralazine hepatitis].
    Presse medicale (Paris, France : 1983), 1985, Mar-02, Volume: 14, Issue:9

    Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Middle Aged

1985
[Chronic drug-induced hepatitis caused by dihydralazine].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1988, Volume: 48, Issue:1

    Topics: Aged; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Liver; Liver Function Tests; Middle Aged

1988
[Drug-induced hepatitis after dihydralazine treatment with fatal consequences].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1988, Volume: 134, Issue:2

    Topics: Aged; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis

1988
[Morphology and pathogenesis of liver injury produced by dihydralazine , propranolol and ketophenylbutazone].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1985, Volume: 130, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Immunity, Cellular; Liver Diseases; Phenylbutazone; Propranolol

1985
[Liver lesions induced by dihydralazine and propranolol].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1985, Volume: 130, Issue:1

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Cholangitis; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis; Propranolol

1985
[Drug-induced hepatitis in a diabetic patient].
    Duodecim; laaketieteellinen aikakauskirja, 1985, Volume: 101, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 1; Dihydralazine; Humans; Hydralazine

1985
[The so-called dihydralazine hepatitis. A contribution to the pathogenesis].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1985, Volume: 45, Issue:6

    Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Liver; Liver Cirrhosis, Biliary; Male; Middle Aged; Necrosis; Propranolol

1985