digoxin and Serotonin-Syndrome

Many life-threatening drug interactions are predictable, avoidable events. Emergency medicine physicians have a responsibility to recognize and prevent drug interactions. Keeping current on the many pharmaceutical therapies,their pharmacology, and potential drug interactions currently represents one of the biggest challenges for emergency medicine practitioners. Using current drug interaction resources and knowing the limited number of medications that are responsible for the most serious drug interactions can ease this seemingly overwhelming burden greatly. Clinicians need to be particularly vigilant when prescribing drugs for patients who are taking medications with potential for drug interactions leading to serious consequences.

Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Cardiotonic Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Digoxin; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Drug Utilization; Emergency Medicine; Emergency Treatment; Humans; Intestinal Absorption; Metabolic Clearance Rate; Nonprescription Drugs; Physician's Role; Risk Factors; Serotonin Agents; Serotonin Syndrome; Tissue Distribution; United States; Warfarin