digoxin has been researched along with Priapism* in 2 studies
1 review(s) available for digoxin and Priapism
| Article | Year |
|---|---|
Stuttering priapism--a review of the therapeutic options.
Priapism is a urological emergency which is commonly classified into low-flow and high-flow priapism. Immediate intervention is required for low-flow cases as the development of ischaemia ultimately leads to long-term erectile dysfunction. Stuttering or recurrent priapism is less well understood. This subtype is characterised by short-lived painful erections and is commonly encountered in patients with sickle cell disease.. A systematic review of the treatment options available for stuttering priapism is presented combined with our own experience in managing this condition over a period of 25 years.. Although numerous medical treatment options have been reported, the majority are through small trials or anecdotal reports.. Stuttering priapism is a condition which is still not well understood and there is no standardised algorithm for the management of this condition. A multicentre randomised trial is required to evaluate the treatment options. Topics: Anemia, Sickle Cell; Digoxin; Drug Delivery Systems; Etilefrine; Hormones; Humans; Male; Orchiectomy; Penile Prosthesis; Phosphodiesterase Inhibitors; Priapism; Procyclidine; Pseudoephedrine; Terbutaline; Treatment Outcome | 2008 |
1 other study(ies) available for digoxin and Priapism
| Article | Year |
|---|---|
The investigation of putative agents, using an in vitro model, to prevent cavernosal smooth muscle dysfunction during low-flow priapism.
To investigate the effect of putative agents for preventing irreversible smooth muscle dysfunction, using an in vitro model of low-flow priapism (a condition conventionally managed using a combination of corporal blood aspiration and instillation of alpha-adrenergic agonists), as failure of detumescence results in a high incidence of erectile dysfunction.. We investigated the effects of several agents (N-acetylcysteine, BayK 8644, glutathione, digoxin, calcium and N(omega)-nitro-l-arginine methyl ester) on the recovery of smooth muscle tone after exposure to 4 h of a combination of hypoxia, glucopenia and acidosis in corpus cavernosum isolated from rabbit.. After 4 h of ischaemia, none of the agents were able to prevent irreversible smooth muscle dysfunction.. Prolonged low-flow priapism leads to smooth muscle dysfunction and fibrosis within the corpus cavernosum. When alpha-adrenergic agents fail to reverse the condition, surgical intervention is required. We showed that the administration of novel agents, including antioxidants, does not prevent smooth muscle dysfunction. Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcysteine; Animals; Calcium; Digoxin; Glutathione; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Muscular Diseases; NG-Nitroarginine Methyl Ester; Penis; Priapism; Rabbits | 2008 |