digoxin and Intestinal-Obstruction

Two patients with atrial fibrillation had abrupt onset of abdominal pain and massive small bowel distension suggesting mesenterial artery embolism. One patient had dilation of the left atrium and ventricle, the other a mitral value prolapse syndrome with a dilated left atrium. Both patients were treated conservatively and gradually recovered. A small bowel series performed several weeks after the acute episode showed loss of normal mucosa and narrowing of a long segment of the small bowel. A control examination in one patient one year later, still revealed jejunal mucosal abnormalities and stenosis, features similar to those occurring in Crohn's disease. Our observations suggest that analogous to ischemic colitis, an entity of acute ischemic small bowel enteritis exists. Mesenteric ischemia apparently can induce a clinical syndrome of "regional enteritis". The radiologic features should not be confused with those of Crohn's disease.

Topics: Aged; Anticoagulants; Digoxin; Heart Diseases; Humans; Intestinal Obstruction; Intestine, Small; Ischemia; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Radiography; Thrombosis

Topics: Digoxin; Electric Countershock; Humans; Intestinal Obstruction; Male; Middle Aged; Postoperative Complications; Potassium Chloride; Quinidine; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome