digoxin and Infections

Topics: Adult; Amino Acids; Cardiac Output; Cardiovascular System; Cells; Digoxin; Energy Intake; Energy Metabolism; Female; Heart Diseases; Humans; Infections; Intubation; Metabolic Diseases; Multiple Organ Failure; Myocardium; Positive-Pressure Respiration; Probability; Respiratory Insufficiency; Vascular Resistance

Many abortion providers use digoxin to induce fetal demise prior to dilation and evacuation (D&E). Our primary objective was to examine the frequency of infection and extramural delivery following digoxin use.. We conducted a retrospective single-cohort study. Inclusion criteria were all women between 18 and 24 weeks of estimated gestational age who received digoxin in preparation for D&E at our outpatient facility. We queried two electronic databases to collect data on the frequency of extramural delivery and the rate of perioperative infection.. From January 1, 2000, to December 31, 2008, 4906 abortions were performed between 18 and 24 weeks of estimated gestation with digoxin injection administered as feticidal agent 1 day prior to D&E. Extramural delivery frequency was 0.30%, and infection frequency was 0.04%. There were no significant differences in the frequency of extramural deliveries across procedure year (p = .2), estimated gestational age (p = .3), race/ethnicity (p = .2) or maternal age (p = .3).. Rates of extramural delivery and infection are acceptably low following digoxin use prior to scheduled D&E.

Topics: Abortion, Induced; Adolescent; Adult; Anti-Arrhythmia Agents; Digoxin; Female; Humans; Infections; Middle Aged; Pregnancy; Retrospective Studies; Young Adult

Topics: Adolescent; Age Factors; Child; Child, Preschool; Digoxin; Electrocardiography; Female; Heart Defects, Congenital; Heart Ventricles; Humans; Infant; Infant, Newborn; Infections; Male; Methods; Myocarditis; Quinidine; Sulfates; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome

Topics: Anti-Bacterial Agents; Antilymphocyte Serum; Arrhythmias, Cardiac; Australia; Azathioprine; Betamethasone; Blood Pressure; Blood Sedimentation; Digoxin; Edema; Electrocardiography; Furosemide; Glycosuria; Heart Auscultation; Heart Transplantation; Hemorrhage; Humans; Hydrocortisone; Hydroxybutyrate Dehydrogenase; Immunosuppressive Agents; Infections; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Intensive Care Units; Isoproterenol; Male; Middle Aged; Postoperative Complications; Respiration; Transplantation Immunology; Transplantation, Homologous; Veins