digoxin and Ebstein-Anomaly

digoxin has been researched along with Ebstein-Anomaly* in 10 studies

Other Studies

10 other study(ies) available for digoxin and Ebstein-Anomaly

ArticleYear
Ebstein's anomaly: epidemiological analysis and presentation of different prenatal management.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:17

    To present the crucial role of echocardiographic examination in perinatal care and analyze influence of prenatal treatment for neonatal outcome. Furthermore, the attempt to answer the question if there was any relationship between the occurrence of fetal Ebstein's anomaly and environmental risk factors in polish population.. Forty-five prenatal diagnoses of Ebstein's anomaly were compiled over the 21-year period (1998‒2018) form our single unit. The analysis included the assessment of maternal parameters (age, past obstetric history, and place of residence) and fetal parameters (sex, gestational age, anatomy, the fetal cardiovascular condition assessed by the CVPS, associated extracardiac anomalies or malformations, prenatal treatment, delivery and follow-up).. The average age of gravida was 29.5 years (± 5.2 years) and gravidae <35 years of age accounted for 80% . There were 43 singleton pregnancies and 2 cases of multiple pregnancy. Ebstein's anomaly was mostly (averagely) diagnosed at 28th week of gestation. Forty-three fetuses had normal karyotypes and two had trisomy 21. Cardiomegaly was present in 91% (41) of fetuses. The average heart area to chest area ratio was 0.56 (± 0.12). In 21 cases, there was only fetal monitoring - echocardiographic examinations and postnatal mortality was 44.4%. In 5 cases, transplacental digoxin treatment was administered and mortality was: 40%. In another 5 cases, only steroid therapy was applied and postnatal mortality was 100%. Steroids and transplacental digoxin treatment were administered in 11 cases and mortality was 63.6%. In 3 last cases transplacental digoxin treatment, steroids and maternal hyperoxygenation therapy were given and mortality was 0%. Cesarean section rate was 49%. Moreover, due to Ebstein's anomaly regional peak of occurrence benzopyrene was deliberated as environmental risk factor.. Fetal Ebstein's anomaly occurred in our population in healthy young women, expecting their first child and malformation was not related to fetus gender, nor to maternal health condition. Our data can be a new signal for the development of novel treatment strategies in therapy in fetuses with Ebstein's anomaly.

    Topics: Adult; Cesarean Section; Digoxin; Ebstein Anomaly; Female; Fetal Diseases; Humans; Infant, Newborn; Pregnancy; Retrospective Studies

2022
[Stubborn nausea and not ease vomiting as a manifestation of glycoside toxicity in a patient with duodenal ulcer and gastric erosions in the background of Ebstein's anomaly].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2010, Issue:2

    In this article is presented the case of development of glycoside intoxication at patient of 26 years old, who has congenital heart disease (Ebstein's anomaly). He also has duodenal ulcer and gastric erosions, associated with Helicobacter Pylori, that were diagnosed for the first time. The clinical observation reflects the necessity of differential diagnostics between glycoside intoxication and manifestation of duodenal ulcer.

    Topics: Adult; Cardiotonic Agents; Digoxin; Duodenal Ulcer; Ebstein Anomaly; Helicobacter Infections; Helicobacter pylori; Humans; Male; Nausea; Stomach Diseases; Vomiting

2010
Sustained supraventricular tachycardia in Ebstein's anomaly.
    The New Zealand medical journal, 2005, May-20, Volume: 118, Issue:1215

    A case is reported of a middle-aged female with congenital heart disease who presented with treatment-resistant supraventricular tachycardia. Supraventricular tachycardias (SVTs) in congenital heart disease (and their management) are discussed. The authors are not aware of any similar reports in the literature.

    Topics: Adenosine; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Ebstein Anomaly; Electric Countershock; Female; Humans; Middle Aged; Tachycardia, Supraventricular; Treatment Outcome

2005
Ebstein's anomaly in a beagle dog.
    The Journal of veterinary medical science, 2003, Volume: 65, Issue:4

    An intact male beagle dog aged 1 year was referred because of shortness of breath, exercise intolerance and cardiac murmur. Based on the results from electrocardiography, thoracic radiography and echocardiography, the dog was diagnosed as Ebstein's anomaly. Although the orally administered digoxin, vasodilators and diuretics partially improved congestive signs, the dog became to be refractory and died 20 months after the diagnosis. Necropsy confirmed malformation and apical displacement of the basal attachment of tricuspid valve leaflets.

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bundle-Branch Block; Cardiotonic Agents; Diagnosis, Differential; Diet, Sodium-Restricted; Digoxin; Diuretics; Dogs; Drug Therapy, Combination; Ebstein Anomaly; Echocardiography; Electrocardiography; Enalapril; Fatal Outcome; Furosemide; Isosorbide Dinitrate; Male; Spironolactone; Vasodilator Agents

2003
Successful prenatal digoxin therapy for Ebstein's anomaly with hydrops fetalis. A case report.
    The Journal of reproductive medicine, 1998, Volume: 43, Issue:8

    Ebstein anomaly is a rare tricuspid valve anomaly. Some fetuses with Ebstein's anomaly have concurrent severe cardiac function impairment, which results in hydrops fetalis. Most of these fetuses are inevitably terminally ill. No reports have demonstrated the potential prenatal therapy for fetuses under such conditions.. Ebstein's anomaly and hydrops fetalis were detected at 28 weeks' gestation. Tricuspid regurgitation with congestive heart failure was observed. From 28 to 34 weeks' gestation, intrauterine therapy with digoxin, 0.75 mg/d, was administered. The fetal hydrops status improved gradually, while the tricuspid valve regurgitation persisted. At 36 weeks' gestation the fetus was delivered normally. During the neonatal phase, digoxin was continued and gradually tapered off. The tricuspid valve regurgitation and cardiomegaly gradually improved.. The favorable outcome in this case supports the positive effect of prenatal digoxin therapy for Ebstein's anomaly with hydrops fetalis. In such conditions, upon the appearance of hydrops and congestive cardiac failure, immediate digoxin therapy may be useful. This successful trial encouraged us to manage such fetuses more aggressively.

    Topics: Adult; Cardiotonic Agents; Digoxin; Ebstein Anomaly; Female; Fetal Diseases; Heart Failure; Humans; Hydrops Fetalis; Infant, Newborn; Pregnancy; Pregnancy Outcome; Treatment Outcome

1998
Digitalization of the mother in treating hydrops fetalis in monochorionic twin with Ebstein's anomaly. Case report.
    Journal of perinatal medicine, 1997, Volume: 25, Issue:3

    Hydrops fetalis thought to be due to Ebstein's anomaly was seen at 22 weeks' gestation in one of two fetuses with a monochorionic placenta. Hydrops was treated with maternal digitalization and resolved by the 28th week of gestation. Hydrops did not recur while maternal digitalization continued. A clinical diagnosis of twin-to-twin transfusion syndrome required termination of the pregnancy at 33 weeks of gestation. The twin with Ebstein's anomaly died 22 hours after birth. The other twin survived and was normal at 19 months of age. Thus, administration of digitalis to the mother controlled hydrops fetalis in one fetus, and ultimately led to the survival of the healthy infant.

    Topics: Adult; Amniotic Fluid; Digoxin; Diseases in Twins; Ebstein Anomaly; Female; Fetal Death; Humans; Hydrops Fetalis; Pregnancy

1997
Epidural analgesia for labour in a patient with Ebstein's anomaly.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:1

    Ebstein's anomaly is an uncommon congenital cardiac defect which is associated with cyanosis and arrhythmias. There have been very few previous reported cases of successful outcome in pregnancy in women with this disorder. We describe the successful analgesic management of an obstetric patient who had been known to have Ebstein's anomaly since childhood. Her first pregnancy was uneventful and analgesia during labour was provided by an epidural. During her second pregnancy she presented to our hospital as her condition had deteriorated. Symptomatic control was achieved with digoxin. Despite this, several episodes of hospitalization were needed pre-partum for rest and oxygen therapy. After the onset of spontaneous labour, analgesia was managed by an epidural using bupivacaine. Invasive monitoring was not deemed appropriate due to increased risk and questionable usefulness. Vaginal delivery was managed with elective lift-out forceps to minimize the stress of pushing. When reviewed two months post-partum she still required digoxin although her symptoms had improved considerably. The successful management of Ebstein's anomaly in pregnancy should include team management from early in pregnancy.

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Bupivacaine; Delivery, Obstetric; Digoxin; Ebstein Anomaly; Female; Follow-Up Studies; Humans; Labor, Obstetric; Obstetrical Forceps; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Care

1995
Wolff-Parkinson-White syndrome and supraventricular tachycardia during infancy: management and follow-up.
    Journal of the American College of Cardiology, 1985, Volume: 5, Issue:1

    The records of 90 patients with Wolff-Parkinson-White syndrome who presented with supraventricular tachycardia in the first 4 months of life were reviewed. Among these, 63% were male. Structural heart disease was present in 20%, most commonly Ebstein's anomaly. All patients presented with a regular narrow QRS tachycardia, and pre-excitation became evident only when normal sinus rhythm was established. Only one infant had atrial flutter and none had atrial fibrillation. Type A Wolff-Parkinson-White syndrome was most common (49%), with heart disease occurring in only 5% of these patients. In contrast, heart disease was identified in 45% of those with type B syndrome. Initially, normal sinus rhythm was achieved in 88% of the 66 infants treated with digoxin with no deaths. Normal sinus rhythm resumed after electrical countershock in 87% of the 15 infants so treated. Maintenance digoxin therapy was used in 85 patients. The Wolff-Parkinson-White pattern disappeared in 36% of the patients. Four infants died of cardiac causes during the mean follow-up period of 6.5 years. Two of these four infants had congenital heart disease; the third, with a normal heart initially, developed ventricular fibrillation and died from a cardiomyopathy considered related to resuscitation. The remaining infant, with a normal heart, died suddenly at 1 month of age. All were receiving digoxin. A wide QRS tachycardia later appeared in three patients, all with heart disease, one of whom died.(ABSTRACT TRUNCATED AT 250 WORDS)

    Topics: Combined Modality Therapy; Digoxin; Ebstein Anomaly; Electric Countershock; Electrophysiology; Female; Follow-Up Studies; Heart Conduction System; Humans; Infant; Infant, Newborn; Male; Recurrence; Sinoatrial Node; Tachycardia; Wolff-Parkinson-White Syndrome

1985
Prolonged prostaglandin E1 infusion: histologic effects on the patent ductus arteriosus.
    Pediatrics, 1981, Volume: 67, Issue:6

    An infant with Ebstein's malformation of the tricuspid valve and severe pulmonic stenosis underwent a 39-day course of prostaglandin E1 infusion, and a histologic study of the ductus arteriosus was undertaken after autopsy. There were marked alterations in the ductal and juxtaductal structures following this prolonged infusion of prostaglandin E1. The internal elastic lamella of the ductus was disrupted in many areas. The media showed widespread areas of disruption with cavity formation. The adventitia adjacent to the junction of the ductus with the pulmonary artery was thickened and infiltrated with mononuclear cells. The nerve trunks in the adventitia were markedly infiltrated with mononuclear cells and showed cavitation as well as considerable surrounding edema. Mucopolysaccharides were increased throughout the ductus. These changes produced increased fragility of the ductal and juxtaductal structures, thus increasing the likelihood of spontaneous aneurysms and rupture, or of tearing or rupture at the aortic and pulmonary junctions at the time of surgical closure of the ductus. Unusual fragility of the ductus, pulmonary artery, and aorta has been observed during ligation of the ductus following prostaglandin E infusions lasting seven and ten days. Additionally, another patient who had received prostaglandin E infusion for six days demonstrated aneurysmal fullness to the ductus arteriosus at autopsy. The histologic findings and intraoperative experience in this study suggest that there may be a real danger of spontaneous or surgically related rupture of the ductus arteriosus after prolonged infusion of prostaglandins.

    Topics: Cardiac Catheterization; Digoxin; Ductus Arteriosus; Ductus Arteriosus, Patent; Ebstein Anomaly; Female; Furosemide; Humans; Infant, Newborn; Infusions, Intra-Arterial; Pregnancy; Prostaglandins E

1981
EBSTEIN'S ANOMALY IN THE NEONATE. A CLINICAL STUDY OF THREE CASES OBSERVED FROM BIRTH THROUGH INFANCY.
    American journal of diseases of children (1960), 1964, Volume: 107

    Topics: Body Weight; Cyanosis; Diagnosis, Differential; Digoxin; Ebstein Anomaly; Electrocardiography; Humans; Infant; Infant, Newborn; Phonocardiography

1964