digoxin and Distal-Myopathies

digoxin has been researched along with Distal-Myopathies* in 1 studies

Other Studies

1 other study(ies) available for digoxin and Distal-Myopathies

Article	Year
Targeting GNE Myopathy: A Dual Prodrug Approach for the Delivery of Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17 ProTides comprise an important class of prodrugs currently marketed and developed as antiviral and anticancer therapies. The ProTide technology employs phosphate masking groups capable of providing more favorable druglike properties and an intracellular activation mechanism for enzyme-mediated release of a nucleoside monophosphate. Herein, we describe the application of phosphoramidate chemistry to 1,3,4- Topics: Animals; Caco-2 Cells; Cell Survival; Cells, Cultured; CHO Cells; Cricetulus; Distal Myopathies; Dose-Response Relationship, Drug; Drug Delivery Systems; Hexosamines; Humans; Molecular Structure; N-Acetylneuraminic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Structure-Activity Relationship; Sugar Phosphates	2019

Article

Year

Targeting GNE Myopathy: A Dual Prodrug Approach for the Delivery of

Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

ProTides comprise an important class of prodrugs currently marketed and developed as antiviral and anticancer therapies. The ProTide technology employs phosphate masking groups capable of providing more favorable druglike properties and an intracellular activation mechanism for enzyme-mediated release of a nucleoside monophosphate. Herein, we describe the application of phosphoramidate chemistry to 1,3,4-

Topics: Animals; Caco-2 Cells; Cell Survival; Cells, Cultured; CHO Cells; Cricetulus; Distal Myopathies; Dose-Response Relationship, Drug; Drug Delivery Systems; Hexosamines; Humans; Molecular Structure; N-Acetylneuraminic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Structure-Activity Relationship; Sugar Phosphates

2019