digoxin has been researched along with Condylomata-Acuminata* in 3 studies
3 other study(ies) available for digoxin and Condylomata-Acuminata
| Article | Year |
|---|---|
No effect of topical digoxin and furosemide gel for patients with external anogenital warts.
Topics: Administration, Topical; Condylomata Acuminata; Digoxin; Furosemide; Gels; Humans | 2020 |
Interphase cytogenetics using biotin and digoxigenin labelled probes: III. Increased sensitivity and flexibility for detecting HPV in cervical biopsy specimens and cell lines.
A monoclonal antibody to digoxin enabled sandwich techniques to be used for the detection of hybridised digoxigenin labelled probes in cultured cells and paraffin wax sections. This system has greater flexibility than alkaline phosphatase conjugated polyclonal antidigoxigenin antibody and permits the use of alternative detector enzymes, such as horseradish peroxidase and fluorescence labels. The APAAP detection system that does not require the use of biotin can also be used in situations where endogenous biotin is a problem. The low level of background staining combined with precise substrate deposition of the amplified peroxidase system gives higher sensitivity and resolution. This permits localisation of closely adjacent chromosomal loci in interphase nuclei. The most sensitive peroxidase based digoxigenin detection system visualises two and a half to 12 copies of human papillomavirus (HPV) per nucleus. This system is also suitable for the analysis of low copy number HPV infection of cervical tissues. Topics: Alkaline Phosphatase; Antibodies, Monoclonal; Biotin; Carcinoma in Situ; Cervix Uteri; Condylomata Acuminata; Digoxigenin; Digoxin; DNA Probes, HPV; Female; Fluorescent Antibody Technique; HeLa Cells; Humans; Interphase; Papillomaviridae; Uterine Cervical Neoplasms | 1991 |
Detection of human papillomavirus DNA in genital condylomata in women and their male partners by using in situ hybridization with digoxygenin labeled probes.
Twelve couples (12 women and their male partners) presenting genital warts were investigated in order to evaluate the sexual transmission of human papillomavirus (HPV) in mutual partners and the localization of HPV DNA. Formalin-fixed, paraffin-embedded biopsy samples of 12 vulvar condylomata, and 12 penile condylomata from male partners were analyzed for the presence of HPV DNA-6, -11, and 16/18 by using in situ hybridization with digoxygenin labeled DNA probes. HPV DNA was identified in 9 women (75%) and in 9 men (75%). HPV-6 was frequently identified, being revealed in 42% of the vulvar specimens, in 67% of the cervical specimens and 58% of the penile specimens. Seven of 9 (77%) positive couples shared the same HPV DNA, and 2 couples harbored different HPV DNA types between the partners. The signal intensity of the HPV DNA was generally strong in superficial cell layers, weak in parabasal or basal cell layers. No malignant lesions resulted from the condyloma acuminatum caused by HPV-6 or -11. There were only mild dysplasia in the both sexes. Topics: Condylomata Acuminata; Digoxigenin; Digoxin; DNA Probes; DNA Probes, HPV; DNA, Viral; Female; Humans; Male; Nucleic Acid Hybridization; Papillomaviridae; Penile Neoplasms; Uterine Cervical Neoplasms | 1990 |