digoxin and Chagas-Disease

The EKG response to exercise and the working capacity in a group of 70 patients with positive serology for Chagas' disease has been determined by stress testing on a bicycle-ergometer, in order to establish the usefulness of such a test in the early diagnosis of Chagas' cardiomyopathy. The exercise EKG provides information which cannot be obtained by other diagnostic procedures, since the stress test can induce or increase ventricular arrhythmia, and is particularly indicated in patients with Chagas' infection and the incipient forms of Chagas' cardiomyopathy. Measuring the working capacity is useful in order to establish the degree of functional impairment of each individual patient. After the application of oral digoxin, no significant increase of ventricular extrasystoles following exercise has been observed and the working capacity has improved in the majority of the studied cases with Chagas' cardiomyopathy.

Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Cardiomyopathies; Chagas Disease; Digoxin; Exercise Test; Female; Humans; Male; Middle Aged

Topics: Arrhythmias, Cardiac; Cardiomyopathies; Chagas Disease; Digoxin; Exercise Test; Heart Rate; Humans

Topics: Adolescent; Adult; Cardiomyopathies; Chagas Disease; Digoxin; Drug Evaluation; Female; Heart Failure; Heart Valve Diseases; Humans; Male; Middle Aged; Postoperative Complications

Topics: Administration, Oral; Animals; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Chagas Disease; Coronary Disease; Digitalis Glycosides; Digoxin; Dogs; Electrocardiography; Heart Diseases; Hemodynamics; Humans; Hypertension; Male; Mitral Valve Insufficiency; Ouabain; Oxygen Consumption; Phonocardiography