digoxin and Cerebral-Hemorrhage

digoxin has been researched along with Cerebral-Hemorrhage* in 2 studies

Other Studies

2 other study(ies) available for digoxin and Cerebral-Hemorrhage

Article	Year
False-positive digoxin measurements due to conjugated metabolite accumulation in combined renal and hepatic dysfunction. American journal of nephrology, 1987, Volume: 7, Issue:5 A 41-year-old man with combined renal and hepatic dysfunction was noted to have marked elevations in serum digoxin concentration subsequent to the discontinuation of digoxin therapy. These elevations (peak value 8.6 ng/ml), as measured by both radioimmunoassay and fluorescence polarization immunoassay, were not associated with electrocardiographic evidence of digitalis toxicity. Using a combined high-performance liquid chromatography/radioimmunoassay, accumulation and immunoassay cross-reactivity of conjugates of digoxigenin monodigitoxoside (cardioinactive metabolites of digoxin) were found to be the basis of the observed false elevation in digoxin concentration. Topics: Acute Kidney Injury; Adult; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Cross Reactions; Diabetes Mellitus, Type 1; Digoxin; False Positive Reactions; Fluorescent Antibody Technique; Humans; Hypertension; Immunoassay; Liver Diseases; Male; Radioimmunoassay; Renal Dialysis	1987
Record linkage for drug monitoring. Journal of epidemiology and community health, 1981, Volume: 35, Issue:1 A study was carried out to assess the feasibility of using record linkage for drug monitoring. For two years, three types of records were collected for a total of 43 117 people: (1) details of basic attributes, such as sex and age; (2) details of prescriptions dispensed; and (3) records of hospital admissions, obstetric deliveries, and deaths. The records about each person were linked together, and analyses were performed to reveal associations between drugs and diagnoses. The study suggested that record linkage would be useful both for generating and for testing hypotheses about the adverse effects of drugs. The method would be especially valuable for detection of delayed effects (such as the induction of cancer), sudden deaths outside hospital, and effects of the fetus-all of which are difficult to study by other means. A full-scale project would need to cover a large population, and some of the practical issues that would arise are discussed. Topics: Aged; Aspirin; Cerebral Hemorrhage; Computers; Delivery, Obstetric; Diarrhea; Digoxin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Medical Record Linkage; Medical Records; Mortality; Patient Admission; Pregnancy	1981

Article

Year

False-positive digoxin measurements due to conjugated metabolite accumulation in combined renal and hepatic dysfunction.

American journal of nephrology, 1987, Volume: 7, Issue:5

A 41-year-old man with combined renal and hepatic dysfunction was noted to have marked elevations in serum digoxin concentration subsequent to the discontinuation of digoxin therapy. These elevations (peak value 8.6 ng/ml), as measured by both radioimmunoassay and fluorescence polarization immunoassay, were not associated with electrocardiographic evidence of digitalis toxicity. Using a combined high-performance liquid chromatography/radioimmunoassay, accumulation and immunoassay cross-reactivity of conjugates of digoxigenin monodigitoxoside (cardioinactive metabolites of digoxin) were found to be the basis of the observed false elevation in digoxin concentration.

Topics: Acute Kidney Injury; Adult; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Cross Reactions; Diabetes Mellitus, Type 1; Digoxin; False Positive Reactions; Fluorescent Antibody Technique; Humans; Hypertension; Immunoassay; Liver Diseases; Male; Radioimmunoassay; Renal Dialysis

1987

Record linkage for drug monitoring.

Journal of epidemiology and community health, 1981, Volume: 35, Issue:1

A study was carried out to assess the feasibility of using record linkage for drug monitoring. For two years, three types of records were collected for a total of 43 117 people: (1) details of basic attributes, such as sex and age; (2) details of prescriptions dispensed; and (3) records of hospital admissions, obstetric deliveries, and deaths. The records about each person were linked together, and analyses were performed to reveal associations between drugs and diagnoses. The study suggested that record linkage would be useful both for generating and for testing hypotheses about the adverse effects of drugs. The method would be especially valuable for detection of delayed effects (such as the induction of cancer), sudden deaths outside hospital, and effects of the fetus-all of which are difficult to study by other means. A full-scale project would need to cover a large population, and some of the practical issues that would arise are discussed.

Topics: Aged; Aspirin; Cerebral Hemorrhage; Computers; Delivery, Obstetric; Diarrhea; Digoxin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Medical Record Linkage; Medical Records; Mortality; Patient Admission; Pregnancy

1981