digoxin and Arteriosclerosis

Topics: Age Factors; Arteriosclerosis; Cardiomyopathy, Hypertrophic; Digoxin; Furosemide; Heart Failure; Humans; Hypertension; Infant; Male; Radiography

This study was undertaken to investigate the hemodynamic effect of prophylactic digitalization before major surgical procedures. Sixteen patients, all admitted for an elective vascular operation for arteriosclerotic disease and all with impaired left ventricular function, were investigated. In half of the patients, digitalis was given before the operation, the other half of the patients served as the control study. The measured parameters were pulmonary artery mean pressure, pulmonary capillary wedge pressure, central venous pressure, mean arterial blood pressure, heart rate, cardiac output, blood volume and arterial, as well as venous, oxygen content. Preoperatively, before digitalization, no significant differences were noted between the two groups at rest and during exercise. Before anesthesia and postoperatively, those given digitalis had improved cardiac function. Those in both groups, however, had a normal hemodynamic response to the surgical trauma. In this study, a definite answer is not provided concerning the usefulness of prophylactic digitalization but an increase in the ability of the digitalized heart to withstand the imposition of a pressure load postoperatively is suggested.

Topics: Aged; Arteriosclerosis; Blood Pressure; Blood Volume; Cardiac Output; Coronary Disease; Digitalis; Digoxin; Female; Heart Rate; Humans; Male; Middle Aged; Oxygen Consumption; Plants, Medicinal; Plants, Toxic; Preoperative Care; Vascular Surgical Procedures

Topics: Aged; Arteriosclerosis; Cognition Disorders; Confusion; Digoxin; Humans

Topics: Animals; Arteriosclerosis; Biopsy; Coronary Disease; Digoxin; Female; Heart Atria; Heart Valve Diseases; Humans; Myocardium; Oxidation-Reduction; Radioimmunoassay; Rats; Tritium

Topics: Adult; Aged; Arteriosclerosis; Digoxin; Female; Heart; Heart Failure; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Stimulation, Chemical; Time Factors

Topics: Aged; Ambulatory Care; Arteriosclerosis; Aspartate Aminotransferases; Blood Pressure; Coronary Disease; Digoxin; Female; Humans; Male; Methods; Middle Aged; Myocardial Infarction; Radioisotopes; Rubidium; Sex Factors

Topics: Aged; Aminosalicylic Acids; Arrhythmias, Cardiac; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Digoxin; Electrocardiography; Furosemide; Heart Conduction System; Humans; Hypertension; Isoniazid; Kidney Failure, Chronic; Lung Diseases, Obstructive; Middle Aged; Myocardial Infarction; Phenytoin

Topics: Aged; Arteriosclerosis; Coronary Disease; Creatinine; Diabetes Complications; Digoxin; Gout; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Time Factors

Topics: Arrhythmias, Cardiac; Arteriosclerosis; Cardiac Output; Coronary Disease; Digoxin; Heart Rate; Humans; Intestinal Absorption; Rheumatic Heart Disease

Topics: Adult; Aged; Arteriosclerosis; Coronary Disease; Digoxin; Female; Heart Diseases; Humans; Male; Middle Aged

Topics: Age Factors; Arteriosclerosis; Atrial Fibrillation; Body Weight; Digoxin; Edema; Female; Heart Failure; Heart Rate; Humans; Hypertension; Lung Diseases; Male; Middle Aged; Organ Size; Spirometry; Syphilis, Cardiovascular

Topics: Acetylcholine; Animals; Arteriosclerosis; Ballistocardiography; Blood Pressure; Digoxin; Heart; Pentobarbital; Rabbits; Vasopressins; Venae Cavae