Page last updated: 2024-08-18

diglycolic acid and Acute Kidney Failure

diglycolic acid has been researched along with Acute Kidney Failure in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Jamison, CN; McMartin, KE; Robinson, CN; Tobin, JD1
Conrad, T; Dunning, CL; Hitt, MJ; Landry, GM; McMartin, KE1
Aw, TY; Conrad, T; Landry, GM; McMartin, KE; Nichols, R1
Abreo, F; Broussard, K; Latimer, B; McMartin, KE; Robinson, CN1

Other Studies

4 other study(ies) available for diglycolic acid and Acute Kidney Failure

ArticleYear
Variable sensitivity to diethylene glycol poisoning is related to differences in the uptake transporter for the toxic metabolite diglycolic acid.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:4

    Topics: Acute Kidney Injury; Animals; Dicarboxylic Acid Transporters; Ethylene Glycols; Humans; Kidney; Rats; Rats, Wistar

2023
Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death.
    Toxicology letters, 2013, Aug-29, Volume: 221, Issue:3

    Topics: Acute Kidney Injury; Cells, Cultured; Glycolates; Humans; Kidney Tubules, Proximal; Lactic Acid; Microscopy, Fluorescence; Mitochondria; Necrosis; Oxygen Consumption; Reactive Oxygen Species; Succinate Dehydrogenase

2013
Diglycolic acid, the toxic metabolite of diethylene glycol, chelates calcium and produces renal mitochondrial dysfunction in vitro.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Acute Kidney Injury; Animals; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Ethylene Glycols; Glutamic Acid; Glycolates; Humans; Kidney; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Malates; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Phosphorylation; Rats; Rats, Wistar

2016
In-vivo evidence of nephrotoxicity and altered hepatic function in rats following administration of diglycolic acid, a metabolite of diethylene glycol.
    Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:3

    Topics: Acute Kidney Injury; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glycolates; Kidney; Liver; Liver Function Tests; Male; Rats; Rats, Wistar; Tissue Distribution

2017
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