digitoxin and Tachycardia

Topics: Adult; Cesarean Section; Digitalis; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Fetal Diseases; Fetal Heart; Heart Failure; Heart Rate; Humans; Hypertension; Infant, Newborn; Labor, Induced; Male; Plants, Medicinal; Plants, Toxic; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol; Tachycardia; Ultrasonography; Verapamil

Topics: Acid-Base Imbalance; Aged; Atropine; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Heart Block; Heart Failure; Heart Ventricles; Humans; Kidney Failure, Chronic; Phenytoin; Potassium; Tachycardia

Topics: Administration, Oral; Aged; Digitalis Glycosides; Digitoxin; Digoxin; Feces; Heart Atria; Heart Failure; Humans; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Liver Diseases; Malabsorption Syndromes; Obesity; Tachycardia; Thyroid Diseases; Tritium; Water-Electrolyte Balance

Topics: Action Potentials; Animals; Cell Membrane; Central Nervous System Diseases; Digitalis; Drug Interactions; Drug Resistance; Heart Conduction System; Heart Ventricles; Humans; Infusions, Parenteral; Injections, Intramuscular; Lidocaine; Liver Circulation; Microsomes, Liver; Myocardial Infarction; Plants, Medicinal; Plants, Toxic; Tachycardia; Time Factors; Ventricular Fibrillation

Topics: Adult; Atrial Fibrillation; Child, Preschool; Death, Sudden; Digitalis; Electric Stimulation; Electrocardiography; Electrophysiology; Heart Conduction System; Humans; Infant; Infant, Newborn; Phytotherapy; Plants, Medicinal; Plants, Toxic; Prognosis; Tachycardia; Wolff-Parkinson-White Syndrome

Topics: Adams-Stokes Syndrome; Adolescent; Adult; Bradycardia; Cardiomegaly; Child; Child, Preschool; Digitalis; Europe; Heart Block; Heart Defects, Congenital; Heart Failure; Humans; Infant; Infant, Newborn; Isoproterenol; Pacemaker, Artificial; Phytotherapy; Plants, Medicinal; Plants, Toxic; Prognosis; Tachycardia; United States

Topics: Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Digitalis; Digitalis Glycosides; Digoxin; Electrocardiography; Heart Block; Heart Failure; Humans; Isoproterenol; Lanatosides; Mitral Valve Stenosis; Pacemaker, Artificial; Tachycardia; Thoracic Surgery; Toxicology; Ventricular Fibrillation

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis; Digitalis Glycosides; Drug Therapy; Heart Block; Humans; Tachycardia; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome

Topics: Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Electric Stimulation Therapy; Procainamide; Quinidine; Tachycardia; Toxicology; Ventricular Fibrillation

The indication for digitalis treatment was investigated in a controlled and prospective study lasting 12 months in 110 patients on long-term haemodialysis. In ten patients, digitalis was needed because of tachyarrhythmia due to atrial fibrillation and in five because of recurrent pulmonary edema. In 57 patients receiving digitoxin, therapy was discontinued for 4 to 6 weeks, whereas 13 patients not yet treated with digitalis, received digitoxin for 4 weeks. Without digitoxin, trial fibrillation occurred in 4 patients, while no patient experienced atrial fibrillation with digitoxin (P = 0.002). In 13 patients, radiological findings (heart enlargement, pulmonary congestion) were better with digitoxin than without. Thus digitoxin appeared to be clearly indicated in 29% of the haemodialysed patients. Additionally, digitalis was indicated in 31 patients because of heart enlargement, pulmonary congestion and (or) previous pulmonary edema. Initially, 76% of the patients were receiving digitoxin, whereas, after the investigation, the rate was only 57% (P less than 0.001). The prospective frequency of clinically apparent digitoxin intoxication was low (3%) and so were the overall toxic plasma digitoxin levels (5%). Digitalis should be given deliberately but not restrictively to haemodialysis patients, since atrial fibrillation (13%) and heart failure (50%) are frequent and often concealed.

Topics: Adult; Aged; Atrial Fibrillation; Cardiomegaly; Clinical Trials as Topic; Digitalis; Digitoxin; Digoxin; Female; Heart Rate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Plants, Medicinal; Plants, Toxic; Pulmonary Edema; Renal Dialysis; Tachycardia; Time Factors

The safety and efficacy of oral verapamil to control exercise tachycardia in 27 patients with atrial fibrillation and 3 with atrial flutter receiving digitalis was evaluated in a double-blind, randomized, crossover study. The heart rate in patients who received verapamil compared with placebo group was lower at rest (mean 69 +/- 13 versus 87 +/- 20 beats/min, p less than 0.01), as was the degree of tachycardia at the end of 3 minutes of a standardized exercise test (104 +/- 14 versus 136 +/- 23 beats/min, p less than 0.01). Doses of verapamil required to achieve suppression of tachycardia were 240 mg/day in 18 patients, 320 mg/day in 6 patients, and 480 mg/day in 3 patients. Only 3 patients complained of adverse effects from verapamil during the double-blind phase of the study. Two patients were discontinued from the study because of adverse reactions. No clinically significant changes during verapamil therapy were observed on the electrocardiogram, chest roentgenogram, echocardiogram or in the laboratory evaluation. Digoxin blood levels were higher in patients who received concomitant verapamil compared with placebo (1.23 +/- 0.59 versus 0.85 +/- 0.46 ng/ml, p less than 0.01), but no patient had signs or symptoms of digitalis toxicity. Thus, oral verapamil given in addition to digitalis is a safe and effective agent in the treatment of patients with chronic atrial fibrillation or flutter to decrease exercise-induced tachycardia.

Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Clinical Trials as Topic; Digitalis; Digoxin; Double-Blind Method; Female; Humans; Male; Middle Aged; Physical Exertion; Placebos; Plants, Medicinal; Plants, Toxic; Random Allocation; Tachycardia; Verapamil

Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Cardiac Complexes, Premature; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Digitalis Glycosides; Digitoxin; Heart Aneurysm; Heart Failure; Heart Valve Diseases; Humans; Hypertension; Kidney Diseases; Lung Diseases; Middle Aged; Spinal Diseases; Tablets; Tachycardia

Topics: Aged; Digitalis; Digoxin; Electrocardiography; Female; Humans; Tachycardia; Ventricular Fibrillation

The records of 121 patients admitted to the Medical Intensive Care Unit (MICU) of Chang Gung Memorial Hospital with severe chronic obstructive pulmonary disease (COPD) requiring mechanical ventilation were reviewed retrospectively. Eighty-seven percent (20/23) of the patients with multifocal atrial tachycardia (MAT) expired during their ICU admission in contrast to 23.5% (23/98) of those without MAT. The only differences between these two groups were incidence of cor pulmonale, and right axis deviation, right bundle branch block, pulmonale P in electrocardiogram. MAT might be considered as a grave prognostic sign in patients with COPD severe enough to require mechanical ventilation.

Topics: Aged; Digitalis; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Plants, Medicinal; Plants, Toxic; Prognosis; Pulmonary Heart Disease; Respiration, Artificial; Tachycardia

Effects of intravenous (IV) and intravertebral arterial (IA) administrations of alpha-2 adrenoceptor agonist, clonidine (CLO) and its antagonist, yohimbine (YOH, 0.05 mg/kg, IA), on the ventricular tachycardia (VT) induced with IV acetyl strophanthidin (AS) were studied in cats anesthetized with intraperitoneal chloralose. IVAS does-dependently produced cardiac arrhythmias including complete atrioventricular conduction block (118 +/- 14 micrograms/kg), junctional tachycardia (128 +/- 20 micrograms/kg), multiform ventricular premature beats (157 +/- 21 micrograms/kg) and sustained VT (220 +/- 23 micrograms/kg). IACLO dose for terminating VT induced with IVAS was about one fifth of IVCLO dose. IACLO dose for terminating VT induced with IVAS + IVYOH was significantly higher than that in VT induced with IVAS (14.8 +/- 3.7 vs 5.8 +/- 1.0 micrograms/kg, p less than 0.005). These experiments clearly demonstrated that IAYOH specifically antagonized the antiarrhythmic effect of IA CLO on the AS-induced VT. Since small dose of IA administration of the drugs acts mainly on the central nervous system, we suggest that the antiarrhythmic effect of CLO on AS-induced VT is likely through the central alpha-2 adrenoceptor.

Topics: Animals; Anti-Arrhythmia Agents; Cats; Clonidine; Digitalis; Female; Heart Ventricles; Male; Plants, Medicinal; Plants, Toxic; Receptors, Adrenergic, alpha; Strophanthidin; Tachycardia; Yohimbine

Using two-stage coronary-ligation-, digitalis- and adrenaline-induced ventricular arrhythmias in beagles, antiarrhythmic effects of AN-132 were examined, and the minimum effective plasma concentration for each arrhythmia model was determined. AN-132 suppressed all the arrhythmias, and the minimum effective plasma concentrations for arrhythmias induced by 24-hour coronary ligation, 48-hour coronary ligation, digitalis, and adrenaline were 3.4-4.6, 1.5-2.3, 0.83, and 9.3 micrograms/ml, respectively. The concentration for adrenaline-induced arrhythmia was significantly higher than that of 24-hour coronary ligation arrhythmia, and it was also higher than that of digitalis arrhythmia. This pharmacologic profile is similar to those of pirmenol and mexiletine. Since AN-132 had no deleterious effects on the hemodynamics and the central nervous system, it may become a clinically useful antiarrhythmic drug.

Topics: Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Digitalis; Dogs; Dose-Response Relationship, Drug; Epinephrine; Ethylenediamines; Female; Ligation; Male; Plants, Medicinal; Plants, Toxic; Tachycardia; Ventricular Function

In this paper we report the first adult case of an "idiopathic" ventricular bidirectional tachycardia (BT), in a 57 year old woman. The tachycardia, at the time of our observation, was incessant in type and had a slightly irregular frequency of about 140 bpm. BT initiated and terminated abruptly, without any temporal relationship to the preceding RR interval, or the QRS morphology. The interval between the two alternating QRS patterns often varied over a wide range of values. The BT could be interrupted only by overdrive atrial and ventricular stimulation, but promptly reappeared as pacing was discontinued. Therapy with quinidine associated with propranolol was effective on a long term trial. The vectorcardiographic analysis and the electrophysiologic investigation demonstrated a ventricular origin of the BT, localizing its site of origin to common myocardial tissue, probably near the two left hemifascicles. Our data could not elucidate the electrogenetic mechanism of this ventricular arrhythmia, because of its chaotic behavior.

Topics: Digitalis; Electrocardiography; Electrophysiology; Female; Humans; Middle Aged; Plants, Medicinal; Plants, Toxic; Tachycardia; Vectorcardiography

Topics: Digitoxin; Heart Failure; Humans; Tachycardia

During digitalis-induced, sustained, monomorphic ventricular tachycardia, programmed electrical stimulation was performed and the effect on the first post-pacing QRS morphology was determined. Ventricular tachycardia was induced in nine conscious dogs with chronic complete atrioventricular block by administering digoxin i.v. 0.1 mg/kg given in 1-1 1/2 hour. Spontaneous ventricular tachycardia most frequently had a right bundle branch block morphology and an extreme left axis suggesting an origin in the apex of the left ventricle. Less frequently, a left bundle branch block-like configuration with an intermediate axis was observed, compatible with an origin in the basal part of the right ventricle. Following pacing close to one of these predilection sites, the first post-pacing QRS morphology suggested an origin close to the site of stimulation. Pacing distant from these predilection sites resulted in fusion complexes between electrical activation from these predilection sites and the stimulation site. The amount of fusion depended on interstimulus interval and the number of stimuli. Long interstimulus intervals and few stimuli induced a QRS complex similar to that of the spontaneous tachycardia. The faster and longer the stimulation train, the more the QRS complex became similar to the paced QRS complex. Similar findings were also observed on decreasing the last paced interval only. Our findings suggest that triggered activity is the underlying mechanism for the first post-pacing QRS complex. QRS configuration and the relation between the R-R interval and QRS configuration during tachycardia suggest that triggered activity is also the mechanism for the spontaneously occurring ventricular tachycardia during digitalis intoxication. These observations may have important clinical implications.

Topics: Animals; Cardiac Pacing, Artificial; Digitalis; Dogs; Electrocardiography; Female; Heart Block; Male; Plants, Medicinal; Plants, Toxic; Tachycardia

In a review of the records of 81 patients with the discharge diagnosis of digitalis toxicity, I found a preponderance of very old patients, many of whom had anorexia, nausea, and prerenal azotemia. Arrhythmias were common (93%) and reflected enhanced automaticity, enhanced AV block, or both. Atrial fibrillation with complete heart block and a regular junctional rhythm should particularly elicit suspicion of digitalis toxicity. Atrial tachycardia with block is less specific and less frequent.

Topics: Adult; Age Factors; Aged; Anorexia; Arrhythmias, Cardiac; Atrial Fibrillation; Digitalis; Digoxin; Heart Atria; Heart Block; Humans; Middle Aged; Nausea; Plants, Medicinal; Plants, Toxic; Radioimmunoassay; Tachycardia; Uremia

Multiple cystic brain lesions in neonates have been described as a result of a variety of causes. All events described thus far in association with multicystic encephalomalacia (MCE) seem to point to hypoxic-ischaemic injury as the common factor for this particular form of central nervous system damage. We describe a neonate in whom repeated, prolonged episodes of intrauterine tachycardia had been documented. Congestive heart failure and fetal hydrops were present at birth and MCE at the age of 13 wk. The obvious relationship between this child's intrauterine tachycardia and his MCE points to the fact that any fetus with prolonged tachycardia should be considered at risk of severe brain damage.

Topics: Adult; Cesarean Section; Digitalis; Encephalomalacia; Female; Fetal Diseases; Humans; Infant, Newborn, Diseases; Labor, Induced; Plants, Medicinal; Plants, Toxic; Pregnancy; Tachycardia; Tomography, X-Ray Computed

In most cases pacemaker patients represent a diverse geriatric group in which ECG and clinical signs are of minor usefulness in diagnosing digitalis toxicity. We therefore determined serum glycoside concentrations in 200 consecutive patients attending our pacemaker clinic (with a mean maintenance dose of 0.093 mg digitoxin per day) and tried to correlate these to clinical, ECG and chemical findings. Multivariate analyses were also carried out to assess whether serum digitoxin concentrations lay in a subtherapeutic (0 to 8.99 ng/ml), therapeutic (9 to 27 ng/ml) or toxic (above 27 ng/ml) range on the basis of a combination of variables. The mean digitoxin concentration was 24.0 +/- 10.3 ng/ml (0 to 45 ng/ml) and correlated poorly with patient compliance (r = 0.36), serum potassium (r = 0.24), weight (r = 0.17) and digitoxin dose (r = 0.13), but not with ECG and subjective or clinical findings. A prediction of the three ranges of the serum digitoxin concentration was possible by means of variable compliance, body weight and digitoxin dose with a probability of up to 79%. In view of the above-mentioned problems indications for digitalis therapy in pacemaker patients must be constantly reviewed and control determination of serum digitoxin concentration should be frequently undertaken.

Topics: Adult; Aged; Cardiac Complexes, Premature; Digitoxin; Electrocardiography; Female; Humans; Male; Middle Aged; Pacemaker, Artificial; Patient Compliance; Tachycardia

Topics: Aged; Digitalis; Drug Therapy, Combination; Female; Heart Rate; Humans; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Tachycardia; Verapamil

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Digitalis; Emergencies; Humans; Plants, Medicinal; Plants, Toxic; Tachycardia; Wolff-Parkinson-White Syndrome

Nine infants with episodic or continuous chaotic atrial rhythm (CAR) are presented. In addition to 3 or more different P-wave contours, atrial rates greater than 100 per minute, variable PP, RR, and PR intervals, and a discrete isoelectric baseline, findings included atrial rates that varied from a low of 50 to 120 to a high of 140 to 270 per minute, ventricular rates that varied from a low of 40 to 50 to a high of 180 to 270 per minute, and periodic sinus arrest with junctional escape rhythm. Except for the arrhythmia, all had a normal cardiac examination, ECG, chest x-ray film, and echocardiogram. Six infants were otherwise normal; one had an orbital rhabdomyosarcoma; one had neonatal asphyxia; and one had respiratory distress, bronchopulmonary dysplasia, and an intraventricular cerebral hemorrhage. The CAR persisted from 3 days to 20 months; it spontaneously reverted to normal sinus rhythm in 8 infants and persists in 1 infant at age 7 months. Digoxin (4 patients), propranolol hydrochloride (3 patients), quinidine sulfate (2 patients), and lidocaine (1 patient) did not alter the CAR. No patient had heart failure secondary to the CAR, although three also had episodes of sustained atrial tachycardia, which while present caused heart failure. All patients are functioning normally at home and have normal findings on cardiac examination and have normal ECGs at ages 3 to 38 months. Seven are in normal sinus rhythm, one has rare atrial premature contractions, and one has persistent CAR. We conclude that specific treatment was not necessary in these infants with CAR, except in those with associated sustained atrial tachycardia, which itself may cause heart failure.

Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitoxin; Electrocardiography; Female; Follow-Up Studies; Heart Atria; Humans; Infant; Infant, Newborn; Male; Tachycardia; Tachycardia, Paroxysmal

Topics: Adult; Cholestyramine Resin; Digitoxin; Female; Heart Block; Humans; Suicide, Attempted; Tachycardia

Topics: Atrial Fibrillation; Digitalis; Heart Conduction System; Heart Rate; Humans; Plants, Medicinal; Plants, Toxic; Tachycardia; Wolff-Parkinson-White Syndrome

In animal experiments heterologous digoxin-specific F(ab')2 antibody fragments have been found to be effective for the treatment of arrhythmias induced by toxic doses of digoxin. So far they have been successfully employed in three patients suffering from digoxin poisoning. The present study was undertaken to test whether these antibodies are also effective in the treatment of digitoxin poisoning. Ventricular tachycardia, induced in digitalized cats by intravenous injections of digitoxin, was fatal in four out of five controls. However, sinus rhythm was reinstated in all the animals treated with digoxin-specific F(ab')2 after onset of the arrhythmia. Cross-reactivity between the antibodies used and digitoxin, while slight in vitro, is, nevertheless, sufficient to justify their clinical use in cases of digitoxin poisoning.

Topics: Animals; Antibodies; Antibody Specificity; Cats; Cross Reactions; Digitoxin; Digoxin; Female; Immunoglobulin Fab Fragments; Male; Tachycardia

Topics: Aged; Digitoxin; Humans; Injections, Intravenous; Magnesium; Male; Tachycardia

The effects of Fab fragments of high-affinity specific antibodies have been studied in a canine experimental model of lethal digitoxin toxicity. Selected antiserum from sheep immunized and boosted with a digoxin-serum albumin conjugate contained antibodies that cross-reacted with digitoxin with an average intrinsic association constant of 1.4 x 10(10) M(-1) as determined by equilibrium dialysis. Rapid second-order association kinetics (k(f) = 3.7 x 10(6) M(-1) per s) and slow dissociation kinetics (k(r) = 1.9 x 10(-4) per s) were documented for the antibody-digitoxin complex. Eight dogs given 0.5 mg/kg digitoxin intravenously developed ventricular tachycardia after 23+/-4 (SEM) min. Control nonspecific Fab fragments were then given. All animals died an average of 101+/-36 min after digitoxin administration. Another eight dogs given the same digitoxin dose similarly developed ventricular tachycardia after 28+/-3 min. This group then received a molar equivalent dose of specific Fab fragments intravenously over 3 min, followed by a 30-min infusion of one-third of the initial dose. All dogs survived. Conducted sinus beats reappeared 18+/-4 min after initial Fab infusion, and stable normal sinus rhythm was present at 54+/-16 min. Plasma total digitoxin concentrations increased threefold during the hour after initial Fab infusion, while plasma free digitoxin concentration decreased to less than 0.1 ng/ml. Effects on digitoxin pharmacokinetics of these Fab fragments and the antibody population from which they were derived were further investigated in a primate species. Unlike common laboratory animals previously studied, the rhesus monkey was found to have a prolonged elimination half-life, estimated at 135 and 118 h by radioimmunoassay and [(3)H]digitoxin measurements, respectively, similar to man and thus providing a clinically relevant experimental model. Intravenous administration of 2 mol of specific Fab fragments per mole of digitoxin 6 h after 0.2 mg of digitoxin produced a rapid 4.3-fold increase in plasma total digitoxin concentration followed by a rapid fall (t((1/2)) 4 h) accompanied by a 14-fold enhancement of urinary digitoxin excretion over control values during the 6-h period after Fab was given. Analytical studies were consistent with increased excretion of native digitoxin rather than metabolites, and the glycoside was found in equilibrium dialysis studies to be excreted in the urine in Fab-bound form. Administration of 2 mol of specific antibod

Topics: Animals; Antibodies; Antigen-Antibody Complex; Cross Reactions; Digitoxin; Dogs; Half-Life; Heart; Immune Sera; Immunoglobulin Fab Fragments; Kinetics; Tachycardia

A report is given on a patient with ischaemic heart disease, whose recompensation in tachyarrhythmia absoluta was for some times possible only by means of unusually high doses of digitoxin (fully effective dose to 5.72 mg, maintenance dose to 0.4 mg). The patient survived a severe decompensation with pulmonary oedema, which appeared under "normal" applications of glycosides, 2 1/2 years under this therapy. Thus it must again be referred to an individual glycoside treatment.

Topics: Aged; Coronary Disease; Digitoxin; Humans; Male; Tachycardia

Extensive clinical experience indicates that cardioversion is the most effective method now available for terminating cardiac tachyarrhythmias. This procedure is not accompanied by depression of myocardial contractility, conductivity, or excitability, a common sequel to the use of antiarrhythmic drugs. Furthermore, the incidence of complications with cardioversion is low. These features of effectiveness, safety, and simplicity permit cardioversion to be used by the noncardiologist physician, who may be less experienced than a cardiologist in recognizing arrrhythmias. Cardioversion has not reduced the need for antiarrhythmic agents; on the contrary, more such drugs are required to maintain normal sinus rhythm. The problem at present is not the terminating a tachyarrhythmia but in preventing its recurrence.

Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Choice Behavior; Digitalis; Electric Countershock; Electricity; Emergencies; Heart Valve Prosthesis; Humans; Pacemaker, Artificial; Plants, Medicinal; Plants, Toxic; Quinidine; Tachycardia; Ventricular Fibrillation

Topics: Adrenergic beta-Antagonists; Adult; Aged; Digitoxin; Electric Countershock; Electrocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Tachycardia; Ventricular Fibrillation

Topics: Aged; Atrial Fibrillation; Digitoxin; Digoxin; Electrocardiography; Female; Heart Arrest, Induced; Heart Conduction System; Humans; Ligation; Pacemaker, Artificial; Propranolol; Quinidine; Reserpine; Tachycardia

Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Digitoxin; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; Heart Atria; Heart Rate; Male; Myocardium; Spinal Cord; Tachycardia; Time Factors; Tritium; Ventricular Fibrillation

Topics: Adenosine Triphosphatases; Animals; Antibodies; Binding Sites; Digitalis; Dogs; Electrocardiography; Enzyme Activation; Heart; Immunoglobulin Fab Fragments; Kinetics; Microsomes; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Protein Binding; Sodium; Strophanthidin; Tachycardia; Time Factors

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis; Digoxin; Electric Countershock; Heart Block; Heart Ventricles; Humans; Lidocaine; Myocardial Infarction; Pacemaker, Artificial; Phenytoin; Phytotherapy; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Ventricular Fibrillation

Topics: Digitalis; Electrocardiography; Female; Heart Block; Humans; Middle Aged; Plants, Medicinal; Plants, Toxic; Tachycardia

Topics: Animals; Chronic Disease; Digitalis; Dogs; Heart Block; Heart Ventricles; Pacemaker, Artificial; Plants, Medicinal; Plants, Toxic; Tachycardia

Topics: Bundle-Branch Block; Digitalis; Electric Countershock; Electrocardiography; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Recurrence; Tachycardia

Topics: Arrhythmia, Sinus; Atrial Fibrillation; Atropine; Digitalis; Electrocardiography; Female; Heart Block; Heart Failure; Humans; Isoproterenol; Male; Pacemaker, Artificial; Phytotherapy; Plants, Medicinal; Plants, Toxic; Prospective Studies; Syncope; Tachycardia

Topics: Atrial Fibrillation; Cardiac Catheterization; Digitoxin; Electrocardiography; Heart Conduction System; Heart Ventricles; Humans; Male; Middle Aged; Pulmonary Embolism; Tachycardia

Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Digitoxin; Digoxin; Ethanolamines; Female; Heart; Heart Rate; Male; Nitrobenzenes; Oxygen; Partial Pressure; Phenethylamines; Tachycardia

Topics: Adult; Aortic Valve Insufficiency; Atrial Fibrillation; Bicarbonates; Blood Proteins; Body Composition; Body Water; Body Weight; Bromine; Cardiac Complexes, Premature; Chlorides; Creatinine; Digitalis; Diuretics; Female; Heart Diseases; Heart Failure; Humans; Male; Middle Aged; Mitral Valve Insufficiency; Phytotherapy; Plants, Medicinal; Plants, Toxic; Potassium; Potassium Chloride; Potassium Isotopes; Sodium; Sodium Isotopes; Spironolactone; Tachycardia

Topics: Adult; Age Factors; Angiography; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Cardiomyopathies; Coronary Disease; Digitalis; Exercise Test; Female; Heart Diseases; Heart Rate; Heart Valve Diseases; Hemodynamics; Humans; Hypoxia; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Statistics as Topic; Tachycardia; Ventricular Fibrillation

Topics: Adrenergic beta-Agonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis; Electrocardiography; Heart; Hemodynamics; Humans; Lidocaine; Phenytoin; Phytotherapy; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Quinidine; Tachycardia

Topics: Adult; Aged; Alkaline Phosphatase; Bilirubin; Bradycardia; Cardiac Complexes, Premature; Creatinine; Digitalis Glycosides; Digitoxin; Electrocardiography; Eye Manifestations; Female; Follow-Up Studies; Gastrointestinal Diseases; Heart Block; Humans; Male; Middle Aged; Poisoning; Tachycardia

Topics: Alkaloids; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Barium; Cardiac Complexes, Premature; Digitoxin; Dogs; Electrocardiography; Epinephrine; Guinea Pigs; Heart Atria; In Vitro Techniques; Ouabain; Petroleum; Tachycardia

To determine whether digoxin-specific antibodies can reverse established digoxin toxicity in the dog, digoxin intoxication was produced by the intramuscular administration of digoxin, 0.09 mg/kg, on each of 3 consecutive days. All animals developed toxic arrhythmias (atrioventricular block, ventricular premature contractions and/or ventricular tachycardia). In control animals not receiving antidigoxin antibodies, the arrhythmias persisted throughout a 6 hr study period. Seven of the nine control dogs were dead within 24 hr and one moribund animal was sacrificed at that time; the last animal died within 48 hr.In contrast, in six of eight dogs given digoxin-specific antibodies in canine plasma and/or rabbit serum, the arrhythmias reverted to a sinus mechanism within 30-90 min after the start of the infusion. At the end of a 6 hr period of study, these six dogs were in normal sinus rhythm and all eight were alive and in normal sinus rhythm at the end of 72 hr. This study provides evidence that digoxin-specific antibodies can reverse severe established digoxin toxicity in the dog.

Topics: Animals; Antibodies; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Digitoxin; Disease Models, Animal; Dogs; Heart Block; Hemagglutination Tests; Immunization, Passive; Poisoning; Potassium; Protein Binding; Serum Albumin; Tachycardia

Topics: Adult; Aged; Antibody Specificity; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Cholesterol; Dehydroepiandrosterone; Digitoxin; Digoxin; Electrocardiography; Estradiol; Female; Heart Block; Heart Failure; Humans; Hydrocortisone; Male; Mathematics; Methods; Middle Aged; Progesterone; Radioimmunoassay; Tachycardia; Testosterone; Tritium

Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Electrocardiography; Humans; Plants, Medicinal; Plants, Toxic; Tachycardia

Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Diagnosis, Differential; Digitalis; Edrophonium; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Plants, Medicinal; Plants, Toxic; Tachycardia; Time Factors

Topics: Apnea; Arrhythmia, Sinus; Atrial Fibrillation; Cardiac Complexes, Premature; Cheyne-Stokes Respiration; Digitoxin; Electrocardiography; Heart Block; Heart Conduction System; Heart Rate; Humans; Respiration; Tachycardia

Because of an error in the manufacture of digoxin tablets a large number of patients took tablets that contained 0.20 mg. of digitoxin and 0.05 mg. of digoxin instead of the prescribed 0.25 mg. of digoxin. The symptoms are described of 179 patients who took these tablets and suffered from digitalis intoxication. Of these patients, 125 had taken the faultily composed tablets for more than three weeks. In 48 patients 105 separate disturbances in rhythm or in atrioventricular conduction were observed on the electrocardiogram. Extreme fatigue and serious eye conditions were observed in 95% of the patients. Twelve patients had a transient psychosis. Extensive ophthalmological observations indicated that the visual complaints were most probably caused by a transient retrobulbar neuritis.

Topics: Aged; Arrhythmias, Cardiac; Depression; Digitoxin; Fatigue; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Heart Block; Humans; Male; Medication Errors; Muscular Diseases; Nausea; Tachycardia; Vision Disorders

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Glycosides; Digitoxin; Digoxin; Heart Rate; Humans; Mathematics; Strophanthins; Tachycardia

Topics: Digitoxin; Drug Tolerance; Female; Humans; Male; Tachycardia

Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Digitoxin; Electrocardiography; Female; Humans; Lidocaine; Pacemaker, Artificial; Postoperative Complications; Potassium Chloride; Procaine; Propranolol; Tachycardia; Ventricular Fibrillation

Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Cardiac Glycosides; Digitoxin; Heart Block; Heart Failure; Heart Rate; Humans; Pacemaker, Artificial; Procainamide; Sympatholytics; Tachycardia

Topics: Animals; Digitalis; Disease Models, Animal; Dogs; Glucose; Heart Ventricles; Infusions, Parenteral; Insulin; Male; Plants, Medicinal; Plants, Toxic; Potassium; Potassium Chloride; Solutions; Tachycardia

Topics: Action Potentials; Animals; Arrhythmia, Sinus; Coronary Vessels; Dibenzazepines; Digitalis; Dogs; Electrocardiography; Heart Block; Heart Conduction System; Heart Rate; In Vitro Techniques; Membrane Potentials; Plants, Medicinal; Plants, Toxic; Purkinje Cells; Tachycardia

Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis; Electric Countershock; Embolism; Female; Humans; Lidocaine; Male; Phytotherapy; Plants, Medicinal; Plants, Toxic; Quinidine; Tachycardia

Topics: Animals; Blood Pressure; Cats; Digitalis; Heart Rate; Heart Ventricles; Ouabain; Phenytoin; Plants, Medicinal; Plants, Toxic; Spinal Cord; Sympathetic Nervous System; Tachycardia

Topics: Atrial Flutter; Calcium; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; Digoxin; Heart Failure; Humans; Lanatosides; Long-Term Care; Ouabain; Quinidine; Tachycardia

Topics: Anti-Bacterial Agents; Anticoagulants; Aortic Coarctation; Bradycardia; Chlorothiazide; Diet, Sodium-Restricted; Digitalis Glycosides; Digitoxin; Digoxin; Drug Tolerance; Electrocardiography; Endocardial Fibroelastosis; Furosemide; Heart Block; Heart Defects, Congenital; Heart Failure; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lanatosides; Myocarditis; Organomercury Compounds; Oxygen Inhalation Therapy; Potassium Chloride; Pulmonary Edema; Tachycardia; Tachycardia, Paroxysmal; Transposition of Great Vessels

Topics: Arrhythmias, Cardiac; Cardiac Surgical Procedures; Digitalis Glycosides; Digitoxin; Digoxin; Electric Stimulation Therapy; Extracorporeal Circulation; Humans; Lidocaine; Myocardium; Perfusion; Phenytoin; Postoperative Complications; Potassium; Tachycardia

Topics: Atrial Fibrillation; Digitoxin; Female; Heart Failure; Humans; Hyperthyroidism; Iatrogenic Disease; Middle Aged; Tachycardia

Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Child; Digitoxin; Electric Countershock; Female; Follow-Up Studies; Heart; Heart Function Tests; Humans; Male; Middle Aged; Quinidine; Rheumatic Heart Disease; Tachycardia

Topics: Adult; Aspartic Acid; Digitoxin; Electrocardiography; Female; Heart Block; Heart Diseases; Humans; Magnesium; Male; Middle Aged; Sodium; Tachycardia

Topics: Aged; Arrhythmia, Sinus; Atrial Fibrillation; Coronary Disease; Digitoxin; Electrocardiography; Female; Heart Block; Humans; In Vitro Techniques; Male; Tachycardia

Topics: Animals; Digitalis; Dogs; Electric Stimulation; Pacemaker, Artificial; Plants, Medicinal; Plants, Toxic; Tachycardia; Ventricular Fibrillation

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis; Electrocardiography; Heart Rate; Humans; Middle Aged; Monitoring, Physiologic; Plants, Medicinal; Plants, Toxic; Quinidine; Tachycardia

Topics: Arrhythmia, Sinus; Bradycardia; Digitalis; Electrocardiography; Heart Block; Heart Rate; Humans; Pacemaker, Artificial; Plants, Medicinal; Plants, Toxic; Sympatholytics; Tachycardia

Topics: Arrhythmias, Cardiac; Atrial Flutter; Bradycardia; Digitalis; Digitalis Glycosides; Electrocardiography; Humans; Phytotherapy; Plants, Medicinal; Plants, Toxic; Procainamide; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal

Topics: Adult; Aged; Chlorothiazide; Coronary Disease; Digitoxin; Electrocardiography; Ephedrine; Heart Block; Humans; Male; Meperidine; Middle Aged; Nitroglycerin; Procainamide; Pulse; Quinidine; Secobarbital; Tachycardia

Topics: Acetyldigitoxins; Digitoxin; Drug Therapy; Humans; Social Behavior; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Supraventricular

Topics: Digitalis Glycosides; Digitoxin; Drug Therapy; Humans; Prednisone; Quinidine; Tachycardia; Tachycardia, Paroxysmal

Topics: Acetyldigitoxins; Digitoxin; Drug Therapy; Humans; Preventive Medicine; Social Behavior; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Toxicology

Topics: Digitalis; Digitalis Glycosides; Digitoxin; Electrocardiography; Geriatrics; Glucans; Tachycardia; Toxicology

Topics: Diagnosis, Differential; Digitalis; Digitalis Glycosides; Digoxin; Drug Therapy; Electrocardiography; Humans; Tachycardia; Tachycardia, Paroxysmal; Toxicology

Topics: Child; Digitalis; Digitalis Glycosides; Drug Therapy; Humans; Preventive Medicine; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Supraventricular

Topics: Digitalis; Electrocardiography; Geriatrics; Humans; Hypokalemia; Tachycardia; Toxicology

Topics: Bradycardia; Delirium; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Gynecomastia; Humans; Lanatosides; Male; Neuritis; Paresthesia; Tachycardia; Thrombocytopenia; Toxicology; Trigeminal Neuralgia; Urticaria

Topics: Acetyldigitoxins; Arteriosclerosis; Atrial Fibrillation; Coronary Disease; Digitoxin; Geriatrics; Heart Failure; Humans; Hypertension; Pulmonary Heart Disease; Rheumatic Heart Disease; Tachycardia

Topics: Adrenal Cortex Hormones; Digitoxin; Electrocardiography; Myocardial Infarction; Myocardium; Pharmacology; Prednisone; Procainamide; Quinidine; Tachycardia; Tachycardia, Supraventricular

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Digitoxin; Electrocardiography; Humans; Pacemaker, Artificial; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal

Topics: Atrial Fibrillation; Cardiovascular Diseases; Digitoxin; Electric Countershock; Heparin; Quinidine; Tachycardia; Tachycardia, Ventricular; Ventricular Fibrillation

Topics: Adams-Stokes Syndrome; Atrial Fibrillation; Digitalis; Digitalis Glycosides; Digitoxin; Drug Therapy; Electrocardiography; Heart Block; Humans; Isoproterenol; Tachycardia; Tachycardia, Paroxysmal; Toxicology; Ventricular Fibrillation

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Cardiac Surgical Procedures; Digitoxin; Drug Therapy; Heart Block; Heart Conduction System; Humans; Mitral Valve Insufficiency; Mitral Valve Stenosis; Postoperative Complications; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal; Thoracic Surgery

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Digitalis; Electrocardiography; Geriatrics; Heart Block; Humans; Parasystole; Quinidine; Tachycardia; Wolff-Parkinson-White Syndrome

Topics: Digitalis; Electrocardiography; Heart Massage; Humans; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Vectorcardiography; Wolff-Parkinson-White Syndrome

Topics: Adrenocorticotropic Hormone; Aminophylline; Anaphylaxis; Antitoxins; Digitalis; Digitalis Glycosides; Epinephrine; Humans; Methylprednisolone; Skin Tests; Steroids; Tachycardia; Tetanus Antitoxin; Tripelennamine; Urticaria

Topics: Chlorides; Digitalis; Digitalis Glycosides; Electrocardiography; Geriatrics; Heart Block; Injections, Intravenous; Potassium; Procainamide; Tachycardia; Tachycardia, Paroxysmal; Toxicology

Topics: Antazoline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Dogs; Electrocardiography; Geriatrics; Histamine H1 Antagonists; Humans; Myocardial Infarction; Research; Tachycardia; Tachycardia, Paroxysmal; Toxicology

Topics: Atrioventricular Block; Digitalis; Digitalis Glycosides; Electrocardiography; Heart Block; Humans; Tachycardia; Tachycardia, Paroxysmal; Toxicology

Topics: Adolescent; Child; Diagnosis, Differential; Digitalis; Digitalis Glycosides; Drug Therapy; Electrocardiography; Heart Auscultation; Humans; Infant; Infant, Newborn; Posture; Procainamide; Prognosis; Quinidine; Reserpine; Tachycardia; Tachycardia, Paroxysmal

Topics: Black People; Digitalis; Electrocardiography; Norepinephrine; Oxygen Inhalation Therapy; Procainamide; Quinacrine; Quinidine; Tachycardia; Tachycardia, Ventricular

Topics: Adolescent; Cardiomegaly; Digitalis; Electrocardiography; Female; Heart Aneurysm; Heart Auscultation; Heart Septum; Heart Valve Diseases; Humans; Maternal Death; Maternal Mortality; Pathology; Prednisone; Pregnancy; Pregnancy Complications, Cardiovascular; Tachycardia

Topics: Arrhythmias, Cardiac; Blood Pressure Determination; Coronary Disease; Digitalis; Digitalis Glycosides; Drug Therapy; Electric Stimulation; Electric Stimulation Therapy; Electrocardiography; Heart Auscultation; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Ventricular; Toxicology

Topics: Angina Pectoris; Atrial Fibrillation; Digitalis; Digitalis Glycosides; Heart Failure; Humans; Hyperthyroidism; Iodine Isotopes; Morbidity; Mortality; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Digitalis Glycosides; Drug Therapy; Electrocardiography; Humans; Tachycardia; Toxicology

Topics: Atrial Fibrillation; Digitalis; Digitalis Glycosides; Drug Therapy; Electrocardiography; Heart Conduction System; Humans; Tachycardia; Toxicology

Topics: Angina Pectoris; Aortic Valve Stenosis; Digitalis; Digitalis Glycosides; Drug Therapy; Electrocardiography; Exercise Test; Heart Septal Defects; Heart Septal Defects, Atrial; Hematocrit; Humans; Hypertension; Mitral Valve Insufficiency; Myocardial Infarction; Polycythemia Vera; Postoperative Care; Potassium; Tachycardia; Tachycardia, Paroxysmal; Water-Electrolyte Balance

Topics: Cardiac Glycosides; Digitalis; Digitalis Glycosides; Diuretics; Drug Therapy; Electrocardiography; Heart Block; Strophanthins; Tachycardia; Tachycardia, Paroxysmal; Toxicology

Topics: Digitalis; Digitalis Glycosides; Electrocardiography; Heart Diseases; Humans; Potassium; Tachycardia

Topics: Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Humans; Procainamide; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal

Topics: Atrioventricular Block; Digitalis; Digitalis Glycosides; Heart Block; Humans; Tachycardia

Topics: Adolescent; Digitalis; Digitalis Glycosides; Electrocardiography; Femoral Vein; Heart Massage; Hospitals, University; Humans; Iliac Vein; Ohio; Popliteal Vein; Pulmonary Embolism; Tachycardia; Thrombophlebitis

Topics: Arrhythmias, Cardiac; Calcium; Cardiac Complexes, Premature; Cats; Digitalis; Digitalis Glycosides; Dogs; Edetic Acid; Electrocardiography; Pharmacology; Potassium; Procainamide; Research; Tachycardia; Toxicology

Topics: Digitalis; Digitalis Glycosides; Electrocardiography; Heart Block; Humans; Pharmacology; Procainamide; Strophanthins; Tachycardia

Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Electric Countershock; Heart Block; Heart Failure; Humans; Hypokalemia; Potassium; Procainamide; Resuscitation; Tachycardia; Tachycardia, Paroxysmal; Toxicology

Topics: Atrial Fibrillation; Atrial Flutter; Cardiotonic Agents; Digitalis; Digitalis Glycosides; Electrocardiography; Heart Failure; Humans; Myocardial Infarction; Pulmonary Edema; Tachycardia; Tachycardia, Paroxysmal

Topics: Adrenal Cortex Hormones; Ascorbic Acid; Balsams; Central Nervous System Stimulants; Digitalis; Digitalis Glycosides; Electrocardiography; Endocardial Fibroelastosis; Humans; Infant; Liver Extracts; Oxygen Inhalation Therapy; Pathology; Penicillins; Radiography, Thoracic; Streptomycin; Tachycardia

Topics: Diagnosis, Differential; Digitalis; Digitalis Glycosides; Electrocardiography; Humans; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Ventricular

Topics: Cardiovascular Diseases; Digitalis; Digitalis Glycosides; Tachycardia; Tachycardia, Ventricular

Topics: Digitalis; Digitalis Glycosides; Electrocardiography; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Heart; Heart Block; Tachycardia; Tachycardia, Supraventricular

Topics: Cardiovascular Diseases; Digitalis; Humans; Plant Extracts; Tachycardia; Tachycardia, Ventricular

Topics: Digitalis; Humans; Tachycardia

Topics: Atrial Fibrillation; Digitalis; Digitalis Glycosides; Heart Atria; Humans; Potassium; Salts; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Supraventricular

Topics: Atrial Fibrillation; Digitalis; Digitalis Glycosides; Heart Block; Humans; Tachycardia; Tachycardia, Supraventricular; Tachycardia, Ventricular

Topics: Atrioventricular Block; Digitalis; Digitalis Glycosides; Heart Block; Humans; Tachycardia

Topics: Atrioventricular Block; Digitalis; Digitalis Glycosides; Heart Block; Humans; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Digitalis Glycosides; Heart Block; Humans; Tachycardia; Tachycardia, Paroxysmal

Topics: Cardiovascular Diseases; Digitalis; Humans; Plant Extracts; Tachycardia; Tachycardia, Ventricular

Topics: Digitalis; Heart Failure; Humans; Tachycardia; Tachycardia, Supraventricular

Topics: Child; Digitalis; Digitalis Glycosides; Humans; Infant; Neostigmine; Plant Extracts; Tachycardia; Tachycardia, Paroxysmal

Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Digitalis; Heart Block; Heart Conduction System; Humans; Potassium; Seizures; Tachycardia; Tachycardia, Ventricular; Ventricular Fibrillation

Topics: Acetyldigitoxins; Atrial Fibrillation; Cardiac Glycosides; Cardiotonic Agents; Digitalis; Digitalis Glycosides; Disease; Heart Diseases; Heart Failure; Humans; Mitral Valve; Tachycardia; Tachycardia, Paroxysmal

Topics: Acetyldigitoxins; Arrhythmias, Cardiac; Digitalis; Tachycardia

Topics: Child; Digitalis; Ephedrine; Infant; Tachycardia; Tachycardia, Paroxysmal

Topics: Cardiovascular Agents; Digitalis; Heart Ventricles; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Diuretics; Edema; Heart Failure; Humans; Organomercury Compounds; Pulmonary Embolism; Tachycardia; Thrombosis

Topics: Atrial Fibrillation; Bundle-Branch Block; Digitalis; Digitalis Glycosides; Heart Block; Heart Diseases; Humans; Quinidine; Tachycardia

Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Digitalis; Digitalis Glycosides; Heart Conduction System; Lanatosides; Tachycardia

Topics: Digitalis; Digitalis Glycosides; Plant Extracts; Tachycardia; Tachycardia, Paroxysmal

Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Digitalis; Humans; Potassium; Tachycardia

Topics: Digitalis; Digitalis Glycosides; Humans; Quinidine; Tachycardia; Tachycardia, Ventricular

Topics: Digitalis; Digitalis Glycosides; Emergency Treatment; Humans; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Digitalis Glycosides; Digitoxin; Humans; Myocardial Infarction; Tachycardia; Tachycardia, Ventricular

Topics: Digitalis; Humans; Potassium; Tachycardia

Topics: Atrial Fibrillation; Digitalis; Digitalis Glycosides; Lanatosides; Plant Extracts; Tachycardia

Topics: Digitalis; Digitalis Glycosides; Heart Diseases; Plant Extracts; Tachycardia

Topics: Digitalis; Digitalis Glycosides; Lanatosides; Tachycardia; Tachycardia, Supraventricular

Topics: Atrioventricular Block; Digitalis; Humans; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Digitalis Glycosides; Plant Extracts; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Digitalis Glycosides; Humans; Plant Extracts; Quinidine; Tachycardia; Tachycardia, Paroxysmal

Topics: Digitalis; Digitalis Glycosides; Plant Extracts; Procainamide; Procaine; Tachycardia; Tachycardia, Ventricular

Topics: Digitalis; Digitalis Glycosides; Lanatosides; Plant Extracts; Tachycardia

Topics: Arrhythmias, Cardiac; Carotid Sinus; Digitalis; Digitalis Glycosides; Drug Overdose; Humans; Tachycardia