digitoxin and Pheochromocytoma

Catecholamine-induced cardiomyopathy is a rare complication of pheochromocytoma. We present a case of pheochromocytoma that developed preoperative heart failure. Left ventricular dilation and severe hypokinesia were demonstrated by echocardiography. Heart failure was successfully treated with digitalis, diuretics and captopril. There were no surgical complications and the follow up showed and improvement on the systolic function evaluated by echocardiography and isotope ventriculography, 3 and 6 months after surgery. We review the pathophysiology and evolution of catecholamine induced cardiomyopathy. Preload reserve can be one of the adaptive mechanisms of the ventricle in catecholamine-induced cardiomyopathy. Conventional therapy of hypertension and heart failure can be effective to correct the symptoms of cardiac dysfunction.

Topics: Adrenal Gland Neoplasms; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathies; Catecholamines; Digitalis; Diuretics; Echocardiography; Follow-Up Studies; Furosemide; Heart Failure; Humans; Male; Middle Aged; Pheochromocytoma; Plants, Medicinal; Plants, Toxic; Time Factors

Topics: Adrenal Gland Neoplasms; Adult; Angiography; Cardiomyopathies; Catecholamines; Digitalis; Electrocardiography; Heart; Humans; Hypertension; Iodine Radioisotopes; Kidney; Male; Organomercury Compounds; Pheochromocytoma; Phytotherapy; Plants, Medicinal; Plants, Toxic; Posture