digitoxin and Heart-Valve-Diseases

Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Cardiac Complexes, Premature; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Digitalis Glycosides; Digitoxin; Heart Aneurysm; Heart Failure; Heart Valve Diseases; Humans; Hypertension; Kidney Diseases; Lung Diseases; Middle Aged; Spinal Diseases; Tablets; Tachycardia

Topics: Age Factors; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Digitoxin; Female; Headache; Heart Diseases; Heart Rate; Heart Valve Diseases; Humans; Ischemia; Male; Middle Aged; Myocardial Infarction; Nausea; Pulmonary Heart Disease; Tachycardia, Paroxysmal

Topics: Clinical Trials as Topic; Coronary Disease; Digitoxin; Digoxin; Electrocardiography; Heart Diseases; Heart Failure; Heart Valve Diseases; Humans; Strophanthins

Left atrial enlargement is a risk factor for the development of atrial fibrillation (AF). Large atrial size increases thromboembolic risk and reduces the success rate of cardioversion. The study aim was to evaluate if left atrial size reduction affects cardiac rhythm in patients with chronic AF undergoing mitral valve surgery.. Twenty-seven patients were analyzed prospectively. The left atrial incision was extended to the left inferior pulmonary vein. Left atrial size reduction was achieved by closure of the left atrial appendage from inside with a double running suture. The same suture plicated the left lateral atrial wall to the roof of the left pulmonary vein inflow and the inferior atrial wall. The atrial septum was plicated by placing stitches of the closing suture line across the fossa ovalis. Rhythm, neurological complications, cardioversion, anticoagulation and anti-arrhythmic medication were evaluated at one year postoperatively and at recent follow up (mean 40 +/- 15 months).. At discharge, five patients (19%) were in sinus rhythm (SR). At one year postoperatively, SR was restored in 17 patients (63%), but five (19%) reported episodes of arrhythmia and AF persisted in 10 (37%). At recent follow up, four patients had died and three were lost to follow up. Among 20 patients examined, 13 (65%) had SR but six reported episodes of arrhythmia and AF persisted in seven (35%). LA diameter was significantly reduced, from 60.2 +/- 9.8 mm preoperatively to 44.5 +/- 7.0 mm at one year after surgery.. The addition of left atrial size reduction to mitral valve surgery is technically simple, and was effective in 63% of patients with chronic AF, restoring predominant SR. In order to influence pathogenetic factors other than size, additional ablative steps may further increase the SR conversion rate. Size reduction may also improve the outcome of other ablative approaches.

Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Cardiopulmonary Bypass; Chronic Disease; Cohort Studies; Digitoxin; Echocardiography; Electric Countershock; Female; Follow-Up Studies; Heart Atria; Heart Conduction System; Heart Valve Diseases; Humans; Male; Middle Aged; Mitral Valve; Postoperative Complications; Sotalol; Survival Analysis; Treatment Outcome; Verapamil

Topics: Aortic Valve; Arrhythmias, Cardiac; Aspirin; Digitalis; Echocardiography; Electrocardiography, Ambulatory; Heart Valve Diseases; Hemodynamics; Mitral Valve; Plants, Medicinal; Plants, Toxic; Warfarin

Topics: Adult; Aged; Animals; Blood Pressure; Digitoxin; Digoxin; Dogs; Echocardiography; Female; Heart Failure; Heart Valve Diseases; Humans; Male; Middle Aged; Muscle Proteins; Myocardium; Rabbits

Topics: Adolescent; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Cardiac Catheterization; Digitoxin; Electrocardiography; Female; Heart Arrest; Heart Injuries; Heart Valve Diseases; Humans; Hyperkalemia; Male; Middle Aged; Pacemaker, Artificial; Prognosis; Sepsis; Shock, Cardiogenic; Thrombosis; Time Factors; Ventricular Fibrillation

Topics: Aged; Arrhythmias, Cardiac; Digitalis Glycosides; Digitoxin; Digoxin; Heart Block; Heart Failure; Heart Valve Diseases; Humans; Middle Aged; Myocardial Infarction; Potassium Deficiency; Strophanthins

Topics: Adult; Aged; Coronary Disease; Digitoxin; Electric Countershock; Electrocardiography; Female; Heart Atria; Heart Block; Heart Defects, Congenital; Heart Valve Diseases; Humans; Male; Middle Aged; Potassium; Prognosis; Tachycardia, Paroxysmal; Verapamil

Topics: Aged; Blood Urea Nitrogen; Calcium; Coronary Disease; Creatinine; Digitalis Glycosides; Digitoxin; Digoxin; Electrocardiography; Evaluation Studies as Topic; Heart Failure; Heart Valve Diseases; Humans; Kidney Failure, Chronic; Middle Aged; Myocardial Infarction; Photometry; Potassium; Radioimmunoassay; Saliva; Specimen Handling; Spectrophotometry, Atomic

Topics: Blood Proteins; Blood Urea Nitrogen; Digitalis Glycosides; Digitoxin; Diuretics; Electrolytes; Heart; Heart Failure; Heart Valve Diseases; Humans; Mitral Valve Insufficiency; Mitral Valve Stenosis; Radiography; Rheumatic Heart Disease

Topics: Adult; Age Factors; Angiography; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Cardiomyopathies; Coronary Disease; Digitalis; Exercise Test; Female; Heart Diseases; Heart Rate; Heart Valve Diseases; Hemodynamics; Humans; Hypoxia; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Statistics as Topic; Tachycardia; Ventricular Fibrillation

Topics: Aged; Atrial Fibrillation; Cardiomyopathies; Diagnosis, Differential; Digitalis; Electrocardiography; Geriatrics; Heart Diseases; Heart Failure; Heart Valve Diseases; Humans; Hypertension; Ischemia; Mitral Valve Insufficiency; Phytotherapy; Plants, Medicinal; Plants, Toxic; Ventricular Fibrillation

Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Azathioprine; Cardiomyopathies; Digitoxin; Heart Transplantation; Heart Valve Diseases; Histocompatibility; Humans; Hydrocortisone; Hydroquinones; Male; Methods; Phlebitis; Postoperative Complications; Serum Globulins; Transplantation, Homologous

Topics: Adams-Stokes Syndrome; Adult; Arthritis, Rheumatoid; Digitalis; Electrocardiography; Heart Block; Heart Valve Diseases; Humans; Male; Middle Aged; Pacemaker, Artificial; Plants, Medicinal; Plants, Toxic; Spondylitis

Topics: Adolescent; Cardiomegaly; Digitalis; Electrocardiography; Female; Heart Aneurysm; Heart Auscultation; Heart Septum; Heart Valve Diseases; Humans; Maternal Death; Maternal Mortality; Pathology; Prednisone; Pregnancy; Pregnancy Complications, Cardiovascular; Tachycardia

Topics: Coronary Disease; Digitalis; Digitalis Glycosides; Heart Diseases; Heart Failure; Heart Valve Diseases; Hypertension; Hypertension, Pulmonary; Hyperthyroidism; Pharmacology; Toxicology; Ventricular Fibrillation

Topics: Aortic Valve; Bicuspid Aortic Valve Disease; Coronary Disease; Digitalis; Disease; Electrocardiography; Heart Defects, Congenital; Heart Failure; Heart Valve Diseases; Humans

Topics: Acetyldigitoxins; Blood Coagulation; Digitalis; Digitalis Glycosides; Disease; Heart Diseases; Heart Valve Diseases; Hemodynamics; Humans; Mitral Valve; Rheumatic Heart Disease

Topics: Digitalis; Disease; Heart Diseases; Heart Valve Diseases; Humans; Injections, Intravenous; Kidney; Lanatosides; Mitral Valve; Renal Circulation

Topics: Digitalis; Digitalis Glycosides; Heart Valve Diseases; Humans; Rheumatic Fever; Rheumatic Heart Disease