digitoxin and Endocardial-Fibroelastosis

A 21-year-old woman with known endocardial fibroelastosis diagnosed when aged 3 months was admitted because of progressive dyspnoea. The physical examination revealed symptoms of heart failure, with pulmonary rales, mild hepatomegaly, and tachyarrhythmia.. The electrocardiogram showed atrial fibrillation, complete right bundle branch block and right ventricular hypertrophy. Echocardiography indicated hypertrophy and dilatation of the right ventricle (61 mm) with tricuspid regurgitation and hypoplasia of the left ventricle. Heart catheterization confirmed pulmonary hypertension (60/46 mmHg) as well as dilatation and hypokinesia of the right ventricle. Right ventricular biopsy showed severe myocardial hypertrophy resulting from secondary pulmonary hypertension, while no evidence of myocarditis or idiopathic dilated cardiomyopathy was found.. Symptoms of heart failure improved under medical treatment with digitalis, angiotensin-converting enzyme inhibitor and diuretics.. Primary endocardial fibroelastosis of the contracted type must be included in the differential diagnosis of heart failure occurring in young adults.

Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Atrial Fibrillation; Cardiac Catheterization; Diagnosis, Differential; Digitalis; Diuretics; Dyspnea; Echocardiography; Electrocardiography; Endocardial Fibroelastosis; Female; Heart Failure; Humans; Phytotherapy; Plants, Medicinal; Plants, Toxic

Topics: Anti-Bacterial Agents; Anticoagulants; Aortic Coarctation; Bradycardia; Chlorothiazide; Diet, Sodium-Restricted; Digitalis Glycosides; Digitoxin; Digoxin; Drug Tolerance; Electrocardiography; Endocardial Fibroelastosis; Furosemide; Heart Block; Heart Defects, Congenital; Heart Failure; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lanatosides; Myocarditis; Organomercury Compounds; Oxygen Inhalation Therapy; Potassium Chloride; Pulmonary Edema; Tachycardia; Tachycardia, Paroxysmal; Transposition of Great Vessels

Topics: Child, Preschool; Digitoxin; Electrocardiography; Endocardial Fibroelastosis; Female; Humans; Infant; Male; Prednisone

Topics: Ascites; Cardiomegaly; Chlorothiazide; Digitoxin; Diuretics; Electrocardiography; Endocardial Fibroelastosis; Heart Atria; Heart Failure; Humans; Organomercury Compounds; Pathology

Topics: Arteritis; Child; Digitoxin; Endocardial Fibroelastosis; Heart Failure; Hemoptysis; Hemosiderosis; Hemosiderosis, Pulmonary; Humans; Hydrochlorothiazide; Lung Diseases; Pathology; Prednisolone

Topics: Angiocardiography; Cardiomegaly; Child; Coronary Vessel Anomalies; Diagnosis, Differential; Digitalis; Digoxin; Drug Therapy; Electrocardiography; Endocardial Fibroelastosis; Glycogen Storage Disease; Humans; Infant; Mumps; Myocarditis; Skin Tests

Topics: Adrenal Cortex Hormones; Ascorbic Acid; Balsams; Central Nervous System Stimulants; Digitalis; Digitalis Glycosides; Electrocardiography; Endocardial Fibroelastosis; Humans; Infant; Liver Extracts; Oxygen Inhalation Therapy; Pathology; Penicillins; Radiography, Thoracic; Streptomycin; Tachycardia